D. Carini

发表

Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives.

W. Price, J. Duncia, J. Santella, 1991, Journal of medicinal chemistry.

Comparative QSAR: angiotensin II antagonists.

C. Hansch, R. Garg, A. Kurup, 2001, Chemical reviews.

Identification of selective inhibitors of cyclin dependent kinase 4.

G. Trainor, S. Cox, S. P. Seitz, 2001, Bioorganic & medicinal chemistry letters.

Nonpeptide angiotensin II receptor antagonists. VIII. Characterization of functional antagonism displayed by DuP 753, an orally active antihypertensive agent.

P. Timmermans, W. Price, J. Duncia, 1990, The Journal of pharmacology and experimental therapeutics.

Nonpeptide Angiotensin II Receptor Antagonist: Losartan

R. Lee, J. Duncia, R. Wexler, 1993 .

Nonpeptide angiotensin II receptor antagonists.

P. Timmermans, W. Price, J. Duncia, 1990, American journal of hypertension.

The discovery of a new class of highly specific nonpeptide angiotensin II receptor antagonists.

P. Timmermans, W. Price, J. Duncia, 1991, American journal of hypertension.

Identification of angiotensin II receptor subtypes.

P. Timmermans, L. Pease, J. Duncia, 1989, Biochemical and biophysical research communications.

Nonpeptide angiotensin II receptor antagonists. XI. Pharmacology of EXP3174: an active metabolite of DuP 753, an orally active antihypertensive agent.

P. Timmermans, W. Price, J. Duncia, 1990, The Journal of pharmacology and experimental therapeutics.

Discrimination of angiotensin II receptor subtypes by dithiothreitol.

J. Duncia, R. Wexler, T. Nguyen, 1989, European journal of pharmacology.

Nonpeptide Angiotensin II Receptor Antagonists: Studies With EXP9270 and DuP 753

P. Timmermans, W. Price, J. Duncia, 1990, Hypertension.

(N-acyl-N-alkyl)glycyl borolysine analogs: A new class of potent thrombin inhibitors

M. Abelman, P. Weber, R. Knabb, 1996 .

Hypotensive action of DuP 753, an angiotensin II antagonist, in spontaneously hypertensive rats. Nonpeptide angiotensin II receptor antagonists: X.

P. Timmermans, W. Price, J. Duncia, 1990, Hypertension.

Non-peptide angiotensin II receptor antagonists. II. Pharmacology of S-8308.

P. Timmermans, W. Price, D. Carini, 1988, European journal of pharmacology.

Nonpeptide angiotensin II receptor antagonists. I. Pharmacological characterization of 2-n-butyl-4-chloro-1-(2-chlorobenzyl)imidazole-5-acetic acid, sodium salt (S-8307).

P. Timmermans, W. Price, D. Carini, 1988, The Journal of pharmacology and experimental therapeutics.

In vitro pharmacology of DuP 753.

P. Timmermans, W. Price, J. Duncia, 1991, American journal of hypertension.

Nonpeptide angiotensin II receptor antagonists. IX. Antihypertensive activity in rats of DuP 753, an orally active antihypertensive agent.

P. Timmermans, W. Price, J. Duncia, 1990, The Journal of pharmacology and experimental therapeutics.

Balanced angiotensin II receptor antagonists. III. The effects of substitution at the imidazole 5-position.

P. Timmermans, J. Duncia, J. Santella, 1994 .

Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 1.

J R Pruitt, R. Knabb, R. Wexler, 1999, Journal of medicinal chemistry.

The discovery of DuP 753, a potent, orally active nonpeptide angiotensin II receptor antagonist

P. Timmermans, W. Price, J. Duncia, 1992, Medicinal research reviews.

DuP 532: a second generation of nonpeptide angiotensin II receptor antagonists.

P. Timmermans, W. Price, J. Duncia, 1991, Biochemical and biophysical research communications.

Practical synthesis and regioselective alkylation of methyl 4(5)-(pentafluoroethyl)-2-propylimidazole-5(4)-carboxylate to give DuP 532, a potent angiotensin II antagonist

M. Pierce, D. Carini, G. Wells, 1993 .

Nonpeptide angiotensin II receptor antagonists. VII. Cellular and biochemical pharmacology of DuP 753, an orally active antihypertensive agent.

P. Timmermans, W. Price, J. Duncia, 1990, The Journal of pharmacology and experimental therapeutics.

Scope and stereochemical course of the addition of (trimethylsilyl)allenes to ketones and aldehydes. A regiocontrolled synthesis of homopropargylic alcohols

D. Carini, R. Danheiser, Carrie A. Kwasigroch, 1986 .

(Trimethylsilyl)allenes as propargylic anion equivalents: synthesis of homopropargylic alcohols and ethers

D. Carini, R. Danheiser, 1980 .

Scope and stereochemical course of the (trimethylsilyl)cyclopentene annulation

A. Basak, D. Carini, R. Danheiser, 1983 .

Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. 3. Structure activity relationships at C3

Angela Smallwood, Chong-Hwan Chang, Steven P. Seitz, 2002 .

Nonpeptide angiotensin II receptor antagonists. III. Structure-function studies.

P. Timmermans, W. Price, J. Duncia, 1989, The Journal of pharmacology and experimental therapeutics.

(Trimethylsilyl)cyclopentene annulation: a regiocontrolled approach to the synthesis of five-membered rings

A. Basak, D. Carini, R. Danheiser, 1981 .

Inhibitors of HIV-1 attachment: The discovery and structure-activity relationships of tetrahydroisoquinolines as replacements for the piperazine benzamide in the 3-glyoxylyl 6-azaindole pharmacophore.

L. Hamann, N. Meanwell, Tao Wang, 2016, Bioorganic & medicinal chemistry letters.

The preparation of (perfluoroalkyl)imidazoles as nonpeptide angiotensin II receptor antagonists

P. Timmermans, R. Wexler, D. Carini, 1993 .

Angiotensin II receptors and angiotensin II receptor antagonists.

P. Timmermans, R. Wexler, D. Carini, 1993, Pharmacological reviews.

The discovery and development of angiotensin II antagonists.

J. Duncia, D. Christ, M. Pierce, 1998, Pharmaceutical biotechnology.

Nonpeptide angiotensin II receptor antagonists: N-[(benzyloxy)benzyl]imidazoles and related compounds as potent antihypertensives.

P. Timmermans, W. Price, J. Duncia, 1990, Journal of medicinal chemistry.

The discovery of potent nonpeptide angiotensin II receptor antagonists: a new class of potent antihypertensives.

P. Timmermans, W. Price, J. Duncia, 1990, Journal of medicinal chemistry.

In vivo pharmacology of DuP 753.

P. Timmermans, W. Price, J. Duncia, 1991, American journal of hypertension.

Potent imidazole angiotensinII antagonists: acyl sulfonamides and acyl sulfamides as tetrazole replacements

W. Greenlee, R. Chang, V. J. Lotti, 1994 .

Rationale for the chemical development of angiotensin II receptor antagonists.

P. Timmermans, J. Duncia, R. Wexler, 1992, American journal of hypertension.

Derives de 4-alkylimidazole

D. Carini, 1991 .

Discovery of losartan, the first angiotensin II receptor antagonist.

P. Timmermans, J. Duncia, R. Wexler, 1995, Journal of human hypertension.

Pharmacology and pharmacokinetics of a novel nonpeptide angiotensin II receptor antagonist--DMP 811.

P. Timmermans, W. Price, R. Wexler, 1995, Clinical and experimental hypertension.

Angiotensin II receptor heterogeneity.

L. Pease, J. Duncia, R. Wexler, 1991, American journal of hypertension.

Balanced angiotensin II receptor antagonists. I. The effects of biphenyl “ortho”-substitution on AT1/AT2 affinities

P. Timmermans, R. Olson, R. Wexler, 1994 .

Pharmacology of DuP 532, a selective and noncompetitive AT1 receptor antagonist.

P. Timmermans, R. Wexler, D. Carini, 1991, The Journal of pharmacology and experimental therapeutics.

Angiotensin II Receptor Antagonists From Discovery to Antihypertensive Drugs

P. Timmermans, W. Price, J. Duncia, 1991, Hypertension.

Nonpeptide angiotensin II receptor antagonists: a novel class of antihypertensive agents.

P. Timmermans, W. Price, J. Duncia, 1990, Blood vessels.

Nonpeptide angiotensin II receptor antagonists.

P. Timmermans, W. Price, J. Duncia, 1990, Trends in pharmacological sciences.

Emilia-Romagna Regional Blood System accreditation as an example of improvement through application of specific requirements: a retrospective analysis

D. Carini, V. Randi, E. Cattadori, 2021, BMJ open quality.

EXP 6803, A Nonpeptide Angiotensin II Receptor Antagonist

P. Timmermans, W. Price, J. Duncia, 1989 .

Indenopyrazoles as Cyclin-Dependent Kinase Inhibitors

S. P. Seitz, D. Carini, C. Burton, 2006 .