C. Almansa

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Synthesis and Structure−Activity Relationship of a New Series of Potent AT1 Selective Angiotensin II Receptor Antagonists: 5-(Biphenyl-4-ylmethyl)pyrazoles

C. Almansa, L. Gomez, F. Cavalcanti, 1997 .

Pharmacological characterization of high‐affinity σ1 receptor ligands with spirocyclic thienopyran and thienofuran scaffold

P. Bednarski, M. Düfer, B. Wünsch, 2019, The Journal of pharmacy and pharmacology.

Synthesis and biological evaluation of the 1-arylpyrazole class of σ(1) receptor antagonists: identification of 4-{2-[5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy]ethyl}morpholine (S1RA, E-52862).

D. Zamanillo, C. Laggner, J. Holenz, 2012, Journal of medicinal chemistry.

A New Pharmacophore Model for the Design of Sigma-1 Ligands Validated on a Large Experimental Dataset

J. Vela, C. Almansa, R. Pascual, 2019, Front. Pharmacol..

Co-crystals as a new approach to multimodal analgesia and the treatment of pain

J. Vela, C. Almansa, C. Plata-Salamán, 2019, Journal of pain research.

Differential Solution Behavior of the New API–API Co-Crystal of Tramadol–Celecoxib (CTC) versus Its Constituents and Their Combination

C. Almansa, Adriana Port, C. Plata-Salamán, 2019, Crystal Growth & Design.

Co-crystal of Tramadol Hydrochlorideâ€“Celecoxib (ctc): A Novel APIâ€“API Co-crystal for the Treatment of Pain

C. Almansa, Ramon MercÃ, Nicolas Tesson, 2017 .

In vitro pharmacological characterization of a new selective angiotensin AT1 receptor antagonist, UR-7280.

C. Almansa, F. Cavalcanti, A. F. de Arriba, 1996, European journal of pharmacology.

Selective sigma-1 receptor antagonists for the treatment of pain.

J. Vela, C. Almansa, 2014, Future medicinal chemistry.

Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioids

D. Zamanillo, X. Codony, L. Romero, 2022, Acta pharmaceutica Sinica. B.

Pyrazolo[3,4-d]pyrimidines as sigma-1 receptor ligands for the treatment of pain. Part 1: 4-acylamino derivatives.

J. Díaz, J. Corbera, Ana Montero, 2017, MedChemComm.

[(3-Pyridylalkyl)piperidylidene]benzocycloheptapyridine derivatives as dual antagonists of PAF and histamine.

C. Almansa, J. García-Rafanell, J. Forn, 1994, Journal of medicinal chemistry.

Versatile three component coupling for the synthesis of pyrazolopyridines and other pyrido fused systems

C. Almansa, E. Carceller, Marina Virgili, 2008 .

Synthesis and Structure−Activity Relationship of a New Series of COX-2 Selective Inhibitors: 1,5-Diarylimidazoles

Carmen Almansa, Robert Soliva, R. Soliva, 2003 .

Synthesis and SAR of a new series of COX-2-selective inhibitors: pyrazolo[1,5-a]pyrimidines.

C. Almansa, L. Gomez, F. Cavalcanti, 2001, Journal of medicinal chemistry.

Improved Synthesis of Tricyclo (5.2.1.04,10) Decane-2,5,8-Trione by a Pauson-Khand Intramolecular Bis-Annulation

A. Torrents, C. Almansa, E. Carceller, 1988 .

Synthesis and chiroptical properties of c3-perhydrotriquinacene derivatives

A. Moyano, C. Almansa, F. Serratosa, 1988 .

4-Aryl-1-oxa-4,9-diazaspiro[5.5]undecane derivatives as dual µ-opioid receptor agonists and σ1 receptor antagonists for the treatment of pain.

Mónica García, J. Vela, C. Almansa, 2019, Journal of medicinal chemistry.

Chemoenzymatic synthesis of 2,6-disubstituted tetrahydropyrans with high σ1 receptor affinity, antitumor and analgesic activity.

E. Laurini, D. Marson, S. Pricl, 2021, European journal of medicinal chemistry.

New water-soluble sulfonylphosphoramidic acid derivatives of the COX-2 selective inhibitor cimicoxib. A novel approach to sulfonamide prodrugs.

C. Almansa, F. Cavalcanti, J. García-Rafanell, 2004, Journal of medicinal chemistry.

Synthesis of tricyclo(5.2.1.04,10)decane-2,5,8-trione from deslongchamps's diketone

A. Moyano, C. Almansa, E. Carceller, 1986 .

Synthesis and biological evaluation of a new series of hexahydro-2H-pyrano[3,2-c]quinolines as novel selective σ1 receptor ligands.

J. Díaz, A. R. Fernández de Henestrosa, J. Benet‐Buchholz, 2013, Journal of medicinal chemistry.

Diphenylpropionic acids as new AT1 selective angiotensin II antagonists.

C. Almansa, L. Gomez, F. Cavalcanti, 1996, Journal of medicinal chemistry.

A Short, Efficient Synthesis of 6-Cyano-1-tetralones

C. Almansa, J. Forn, J. Bartrolí, 1993 .

Stereoselective Synthesis of Tris-endo-tricyclo [5.2.1.04,10]decane-2,5,8-triamine

A. Moyano, C. Almansa, A. Aguilera, 1991 .

Perhydrotriquinacenic hosts. 1. Synthesis, complexation and transport properties of tripodands of C3 symmetry.

A. Moyano, C. Almansa, F. Serratosa, 1991 .

Synthesis and SAR of a New Series of COX‐2‐Selective Inhibitors: Pyrazolo[1,5‐a]pyrimidines.

C. Almansa, F. Cavalcanti, J. García-Rafanell, 2001 .

Perhydrotriquinacenic hosts. 2. Synthesis and complexation properties of speleands of C3symmetry.

A. Moyano, C. Almansa, F. Serratosa, 1992 .

Synthesis and structure-activity relationship study of a new series of selective σ(1) receptor ligands for the treatment of pain: 4-aminotriazoles.

Rosalia Pascual, Carmen Almansa, Adriana Port, 2015, Journal of medicinal chemistry.

Theoretical studies on the inhibition mechanism of cyclooxygenase-2. Is there a unique recognition site?

Carmen Almansa, Robert Soliva, F. J. Luque, 2003, Journal of medicinal chemistry.

4-(2-pyridyl)-2,2-dimethylnaphthalen-1-ones as new potassium channel activators with increased airways selectivity

C. Almansa, F. Cavalcanti, J. García-Rafanell, 1995 .

Tricyclic Triazoles as σ1 Receptor Antagonists for Treating Pain.

A. I. Oliva, J. Díaz, J. Vela, 2021, Journal of medicinal chemistry.

Investigational sigma-1 receptor antagonists for the treatment of pain

J. Vela, C. Almansa, M. Merlos, 2015, Expert opinion on investigational drugs.

Pyrazolo[3,4-d]pyrimidines as sigma-1 receptor ligands for the treatment of pain. Part 2: Introduction of cyclic substituents in position 4.

J. Díaz, J. Corbera, Ana Montero, 2017, MedChemComm.

EST64454: a Highly Soluble σ1 Receptor Antagonist Clinical Candidate for Pain Management.

J. Díaz, R. Maldonado, A. Torrens, 2020, Journal of medicinal chemistry.

Synthesis and Structure-Affinity Relationships of Spirocyclic Benzopyrans with Exocyclic Amino Moiety.

E. Laurini, S. Pricl, B. Wünsch, 2019, Journal of medicinal chemistry.

Propionamide Derivatives as Dual μ-Opioid Receptor Agonists and σ1 Receptor Antagonists for the Treatment of Pain.

Mónica García, M. Pujol, J. Vela, 2021, Journal of medicinal chemistry.

Discovery of EST73502, a Dual μ-Opioid Receptor Agonist and σ1 Receptor Antagonist Clinical Candidate for the Treatment of Pain.

A. R. Fernández de Henestrosa, Mónica García, J. Vela, 2020, Journal of medicinal chemistry.

Pushing the Limits of Computational Structure-Based Drug Design with a Cryo-EM Structure: The Ca2+ Channel α2δ-1 Subunit as a Test Case

Martin Kotev, Rosalia Pascual, Carmen Almansa, 2018, J. Chem. Inf. Model..

Stereoselectivity in Intramolecular Cobalt-Mediated Bis-Annulations Leading to Triquinacene Derivatives

C. Almansa, E. Carceller, F. Serratosa, 1988 .

Synthesis, Chiroptical Properties and Synthetic Applications of Perhydrotriquinacene-1,4,7-Trione

A. Moyano, C. Almansa, M. A. Pericàs, 1989 .

Stereoselectivity in Intramolecular Cobalt-Mediated Bisannulations Leading to Triquinacene Derivatives.

C. Almansa, E. Carceller, F. Serratosa, 1989 .

Co-crystal of tramadol-celecoxib: preclinical and clinical evaluation of a novel analgesic

C. Almansa, M. Merlos, K. Smith, 2019, Expert opinion on investigational drugs.

Discovery of WLB-89462, a New Drug-like and Highly Selective σ2 Receptor Ligand with Neuroprotective Properties.

J. Vela, C. Almansa, M. Merlos, 2023, Journal of medicinal chemistry.

Piperazinyl Bicyclic Derivatives as Selective Ligands of the α2δ-1 Subunit of Voltage-Gated Calcium Channels.

J. Díaz, J. Vela, C. Almansa, 2021, ACS medicinal chemistry letters.

Bicyclic Diazepinones as Dual Ligands of the α2δ-1 Subunit of Voltage-Gated Calcium Channels and the Norepinephrine Transporter.

J. Díaz, J. Vela, C. Almansa, 2021, Journal of Medicinal Chemistry.

WLB-87848, a Selective σ1 Receptor Agonist, with an Unusually Positioned NH Group as Positive Ionizable Moiety and Showing Neuroprotective Activity.

C. Almansa, Ute Christmann, A. Dordal, 2024, Journal of medicinal chemistry.