Aynur O Aptula

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Mechanistic applicability domains for non-animal based prediction of toxicological endpoints. QSAR analysis of the schiff base applicability domain for skin sensitization.

Grace Patlewicz, David W Roberts, G. Patlewicz, 2006, Chemical research in toxicology.

Mechanistic applicability domain classification of a local lymph node assay dataset for skin sensitization.

Petra S Kern, Grace Patlewicz, David W Roberts, 2007, Chemical research in toxicology.

Electrophilic chemistry related to skin sensitization. Reaction mechanistic applicability domain classification for a published data set of 106 chemicals tested in the mouse local lymph node assay.

Grace Patlewicz, David W Roberts, G. Patlewicz, 2007, Chemical research in toxicology.

Skin sensitization: reaction mechanistic applicability domains for structure-activity relationships.

Grace Patlewicz, David W Roberts, G. Patlewicz, 2005, Chemical research in toxicology.

Comparative assessment of methods to develop QSARs for the prediction of the toxicity of phenols to Tetrahymena pyriformis.

Mark T D Cronin, Tatiana I Netzeva, M. Cronin, 2002, Chemosphere.

TIMES-SS--a promising tool for the assessment of skin sensitization hazard. A characterization with respect to the OECD validation principles for (Q)SARs and an external evaluation for predictivity.

Petra S Kern, Sabcho D Dimitrov, Grace Patlewicz, 2007, Regulatory toxicology and pharmacology : RTP.

Stepwise discrimination between four modes of toxic action of phenols in the Tetrahymena pyriformis assay.

Ralph Kühne, Ralf-Uwe Ebert, Gerrit Schüürmann, 2003, Chemical research in toxicology.

Structure-toxicity relationships for aliphatic chemicals evaluated with Tetrahymena pyriformis.

Mark T D Cronin, Tatiana I Netzeva, M. Cronin, 2002, Chemical research in toxicology.

TIMES-SS--a mechanistic evaluation of an external validation study using reaction chemistry principles.

Petra S Kern, Sabcho D Dimitrov, Grace Patlewicz, 2007, Chemical research in toxicology.

Chemical mechanisms for skin sensitization by aromatic compounds with hydroxy and amino groups.

David W Roberts, Steven J Enoch, S. Enoch, 2009, Chemical research in toxicology.

Determinants of skin sensitisation potential

David W Roberts, D. Roberts, A. Aptula, 2008, Journal of applied toxicology : JAT.

Mechanistic applicability domains for nonanimal-based prediction of toxicological end points: general principles and application to reactive toxicity.

David W Roberts, D. Roberts, A. Aptula, 2006, Chemical research in toxicology.

Chemical applicability domain of the Local Lymph Node Assay (LLNA) for skin sensitisation potency. Part 2. The biological variability of the murine Local Lymph Node Assay (LLNA) for skin sensitisation.

Anne Marie Api, David W Roberts, A. M. Api, 2016, Regulatory toxicology and pharmacology : RTP.

Experimental reactivity parameters for toxicity modeling: application to the acute aquatic toxicity of SN2 electrophiles to Tetrahymena pyriformis.

David W Roberts, D. Roberts, A. Aptula, 2010, Chemical research in toxicology.

Non-enzymatic glutathione reactivity and in vitro toxicity: a non-animal approach to skin sensitization.

Grace Patlewicz, David W Roberts, T W Schultz, 2006, Toxicology in vitro : an international journal published in association with BIBRA.

From experiment to theory: molecular orbital parameters to interpret the skin sensitization potential of 5-chloro-2-methylisothiazol-3-one and 2-methylisothiazol-3-one.

David W Roberts, Mark T D Cronin, Aynur O Aptula, 2005, Chemical research in toxicology.