A John Iafrate

发表

Tracking the Evolution of Resistance to ALK Tyrosine Kinase Inhibitors through Longitudinal Analysis of Circulating Tumor DNA.

Markus Riester, Cyril H Benes, S. Digumarthy, 2018, JCO precision oncology.

Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations.

Nikhil Wagle, Gad Getz, Mari Mino-Kenudson, 2015, Cancer discovery.

Polyclonal Secondary FGFR2 Mutations Drive Acquired Resistance to FGFR Inhibition in Patients with FGFR2 Fusion-Positive Cholangiocarcinoma.

Gad Getz, Ignaty Leshchiner, Dejan Juric, 2017, Cancer discovery.

First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations.

Alona Muzikansky, Thomas J Lynch, Bruce E Johnson, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

ALK molecular phenotype in non-small cell lung cancer: CT radiogenomic characterization.

Shota Yamamoto, Rahmi Oklu, Glen J Weiss, 2014, Radiology.

Acquired resistance to crizotinib from a mutation in CD74-ROS1.

Mari Mino-Kenudson, Ryohei Katayama, Sidra Mahmood, 2013, The New England journal of medicine.

Detection of mutations in EGFR in circulating lung-cancer cells.

Mehmet Toner, Alona Muzikansky, Daniel Irimia, 2008, The New England journal of medicine.

FGFR1 Amplification in Squamous Cell Carcinoma of The Lung

Mari Mino-Kenudson, David C Christiani, A. Iafrate, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Analytical Validation of the Next-Generation Sequencing Assay for a Nationwide Signal-Finding Clinical Trial: Molecular Analysis for Therapy Choice Clinical Trial.

Lisa M McShane, Robin D Harrington, Chih-Jian Lih, 2017, The Journal of molecular diagnostics : JMD.

Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

David N Louis, Ultan McDermott, Jeffrey W. Clark, 2010, EMBO molecular medicine.

Hotspots for copy number variation in chimpanzees and humans.

Junjun Zhang, Chris Tyler-Smith, Stephen W Scherer, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Proficiency Testing of Standardized Samples Shows Very High Interlaboratory Agreement for Clinical Next-Generation Sequencing-Based Oncology Assays.

Rakesh Nagarajan, Stephen B Montgomery, Annette S. Kim, 2018, Archives of pathology & laboratory medicine.

Inconsistency and features of single nucleotide variants detected in whole exome sequencing versus transcriptome sequencing: A case study in lung cancer.

Junfeng Xia, Peilin Jia, William Pao, 2015, Methods.

Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma.

Rebecca A Betensky, Matija Snuderl, David N Louis, 2011, Cancer cell.

Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.

Luca Toschi, A. Iafrate, P. Jänne, 2010, Cancer cell.

Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.

Rebecca A Betensky, Tracy T Batchelor, Patrick J Codd, 2007, Clinical cancer research : an official journal of the American Association for Cancer Research.

Genome Editing: A Tool For Research and Therapy: Towards a functional understanding of variants for molecular diagnostics using genome editing

J Keith Joung, Shengdar Q Tsai, J. Joung, 2014, Nature Medicine.

Standardized decision support in next generation sequencing reports of somatic cancer variants

Rodrigo Dienstmann, Fei Dong, Long P Le, 2014, Molecular oncology.

Tumor Heterogeneity and Lesion-Specific Response to Targeted Therapy in Colorectal Cancer.

Mari Mino-Kenudson, Giorgio Corti, Mauro Truini, 2016, Cancer discovery.

The challenges posed by cancer heterogeneity

Robert M Hoffman, John V Frangioni, Kornelia Polyak, 2012, Nature Biotechnology.

Therapeutic strategies to overcome crizotinib resistance in non-small cell lung cancers harboring the fusion oncogene EML4-ALK

Ryohei Katayama, Cyril Benes, A. Iafrate, 2011, Proceedings of the National Academy of Sciences.

Test performance evaluation of SARS-CoV-2 serological assays

Aashish Manglik, Mark S. Anderson, Nevan J Krogan, 2020, Nature Biotechnology.