M Cushman

发表

Design and synthesis of ellipticinium salts and 1,2-dihydroellipticines with high selectivities against human CNS cancers in vitro.

K D Paull, J F Barrett, K. Paull, 1994, Journal of medicinal chemistry.

Synthesis and evaluation of analogues of (Z)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as potential cytotoxic and antimitotic agents.

M. Cushman, E. Hamel, C M Lin, 1992, Journal of medicinal chemistry.

Synthesis of new indeno[1,2-c]isoquinolines: cytotoxic non-camptothecin topoisomerase I inhibitors.

Y Pommier, M Cushman, G Kohlhagen, 2000, Journal of medicinal chemistry.

Synthesis of a series of cytotoxic 2-acyl-1,2-dihydroellipticines which inhibit topoisomerase II.

J F Barrett, R. Devraj, J. Jurayj, 1996, Anti-cancer drug design.

Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2-methoxyestradiol, an endogenous mammalian metabolite of estradiol that inhibits tubulin polymerization by binding to the colchicine binding site.

J. Katzenellenbogen, M. Cushman, E. Hamel, 1995, Journal of medicinal chemistry.

Synthesis of analogs of 2-methoxyestradiol with enhanced inhibitory effects on tubulin polymerization and cancer cell growth.

Y. P. Sachdeva, J. Katzenellenbogen, M. Cushman, 1997, Journal of medicinal chemistry.

Synthesis and evaluation of hydroxylated flavones and related compounds as potential inhibitors of the protein-tyrosine kinase p56lck.

R. Geahlen, M. Cushman, M Cushman, 1991, Journal of natural products.

Design, synthesis, and biological evaluation of cosalane, a novel anti-HIV agent which inhibits multiple features of virus reproduction.

O. Weislow, J. Mcmahon, D. Clanton, 1994, Journal of medicinal chemistry.

Synthesis of a cosalane analog with an extended polyanionic pharmacophore conferring enhanced potency as an anti-HIV agent.

W. Rice, M. Cushman, M Cushman, 1998, Bioorganic & medicinal chemistry letters.

Synthesis and protein-tyrosine kinase inhibitory activities of flavonoid analogues.

R. Geahlen, M. Cushman, M Cushman, 1991, Journal of medicinal chemistry.

Design, synthesis, and biological evaluation of a series of lavendustin A analogues that inhibit EGFR and Syk tyrosine kinases, as well as tubulin polymerization.

R. Geahlen, M. Cushman, M Cushman, 2001, Journal of medicinal chemistry.

Design, synthesis, and biological evaluation of ellipticine-estradiol conjugates.

J F Barrett, J. Katzenellenbogen, R. Devraj, 1996, Journal of medicinal chemistry.

Condensation of imines with homophthalic anhydrides. A convergent synthesis of cis- and trans-13-methyltetrahydroprotoberberines.

M. Cushman, M Cushman, J. Gentry, 1977, The Journal of organic chemistry.

Synthesis and biochemical evaluation of a series of aminoflavones as potential inhibitors of protein-tyrosine kinases p56lck, EGFr, and p60v-src.

A. Kraker, R. Geahlen, H. Zhu, 1994, Journal of medicinal chemistry.

Extension of the polyanionic cosalane pharmacophore as a strategy for increasing anti-HIV potency.

E. De Clercq, C. Pannecouque, D. Schols, 1999, Journal of medicinal chemistry.

The condensation of succinic anhydrides with Schiff bases. Scope and mechanism.

M. Cushman, M Cushman, N. Castagnoli, 1971, The Journal of organic chemistry.

Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.

A K Chakraborti, C M Lin, E Hamel, 1991, Journal of medicinal chemistry.