T. Nagase

发表

Modulation of the mevalonate pathway and cell growth by pravastatin and d-limonene in a human hepatoma cell line (Hep G2).

Y. Matsuzawa, S. Kawata, H. Ishiguro, 1994, British Journal of Cancer.

Manumycin and gliotoxin derivative KT7595 block Ras farnesylation and cell growth but do not disturb lamin farnesylation and localization in human tumour cells.

Y. Matsuzawa, S. Kawata, H. Ishiguro, 1997, British Journal of Cancer.

Inhibition of cell growth of human hepatoma cell line (HepG2) by a farnesyl protein transferase inhibitor: A preferential suppression of ras farnesylation

Y. Matsuzawa, T. Ito, S. Kawata, 1996, International journal of cancer.

Suppression of Human Pancreatic Cancer Growth in BALB/c Nude Mice by Manumycin, a Farnesyl:protein Transferase Inhibitor

Y. Matsuzawa, S. Kawata, H. Ishiguro, 1996, Japanese journal of cancer research : Gann.

Reduced risk of hepatocellular carcinoma after interferon therapy in aged patients with chronic hepatitis C is limited to sustained virological responders

Y. Imai, N. Hayashi, A. Kasahara, 2010, Journal of viral hepatitis.

Efficacy of combination therapy of interferon-α with ursodeoxycholic acid in chronic hepatitis C: A randomized controlled clinical trial

Y. Matsuzawa, S. Kawata, S. Tamura, 1997, Journal of Gastroenterology.

Effect of farnesyltransferase overexpression on cell growth and transformation

Y. Matsuzawa, I. Matsumura, S. Kawata, 1999, International journal of cancer.

Increase in the active form of 3-hydroxy-3-methylglutaryl coenzyme A reductase in human hepatocellular carcinoma: possible mechanism for alteration of cholesterol biosynthesis.

Y. Matsuzawa, S. Kawata, S. Tamura, 1990, Cancer research.

A case of autoimmune cholangitis with autoimmune thrombocytopenic purpura.

Y. Matsuzawa, Y. Tomiyama, S. Kawata, 2000 .

Modulation ofthemevalonate pathwayandcell growth bypravastatin andd-limonene ina humanhepatoma cell line (HepG2)

Y. Matsuzawa, S. Kawata, H. Ishiguro, 1994 .

Gelation of Limulus Amoebocyte Lysate by Simple Polysaccharides

T. Mikami, T. Nagase, Shigeo Suzuki, 1982 .

Lethal Effect of Neutral Mannan Fraction of Bakers' Yeast in Mice

T. Mikami, C. Schuerch, T. Nagase, 1984, Microbiology and immunology.

Pyrogenicity of Yeast Mannans in Rabbits

T. Mikami, T. Nagase, Shigeo Suzuki, 1984, Microbiology and immunology.

Ribavirin dose reduction raises relapse rate dose‐dependently in genotype 1 patients with hepatitis C responding to pegylated interferon alpha‐2b plus ribavirin

Y. Imai, N. Hayashi, A. Kasahara, 2009, Journal of viral hepatitis.

Development of prostaglandin D2 receptor antagonist: discovery of highly potent antagonists.

H. Nakai, T. Nagase, M. Iwahashi, 2004, Bioorganic & medicinal chemistry.

Discovery of a new class of potent, selective, and orally active prostaglandin D2 receptor antagonists.

M. Toda, H. Nakai, T. Nagase, 2004, Bioorganic & medicinal chemistry.

3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 3: Synthesis, metabolic stability, and biological evaluation of optically active analogs.

M. Toda, H. Nakai, Y. Tobe, 2010, Bioorganic & medicinal chemistry.

TOTAL SYNTHESIS OF ACANTHACEREBROSIDE A AND ASTROCEREBROSIDE A VIA A CHIRAL EPOXIDE INTERMEDIATE DERIVED FROM L-QUEBRACHITOL

Seiichiro Ogawa, Katsuyuki Murai, T. Nagase, 1998 .

Discovery of novel N-acylsulfonamide analogs as potent and selective EP3 receptor antagonists.

M. Toda, H. Nakai, K. Yoshikawa, 2010, Bioorganic & medicinal chemistry letters.

Production of leukotrienes from mouse peritoneal macrophages by treatment with a neutral subfraction of bakers' yeast mannan.

T. Mikami, T. Nagase, M. Suzuki, 1988, Journal of pharmacobio-dynamics.

Mitogenic Effect of the Mannans from Saccharomyces cerevisiae on Mouse Spleen Lymphocytes

T. Mikami, T. Nagase, Tatsuji Matsumoto, 1982, Microbiology and immunology.

Lamivudine-to-entecavir switching treatment in type B chronic hepatitis patients without evidence of lamivudine resistance

Y. Imai, N. Hayashi, A. Kasahara, 2009, Journal of gastroenterology.

Factors contributing to antiviral effect of adefovir dipivoxil therapy added to ongoing lamivudine treatment in patients with lamivudine-resistant chronic hepatitis B

Y. Imai, N. Hayashi, A. Kasahara, 2009, Journal of Gastroenterology.

The efficacy of extended treatment with pegylated interferon plus ribavirin in patients with HCV genotype 1 and slow virologic response in Japan

Y. Imai, N. Hayashi, A. Kasahara, 2011, Journal of Gastroenterology.

Two cases of acute hepatitis B complicated with amebic liver abscess

Taku Yasumoto, T. Nagase, K. Kiyomizu, 2006 .

Hepatocellular Carcinoma (hcc) Causes Death in Patients with Cirrhosis and Is One of the Most Prevalent Malignant Tumours Effect of Pravastatin on Survival in Patients with Advanced Hepatocellular Carcinoma. a Randomized Controlled Trial

Y. Matsuzawa, S. Kawata, T. Nagase, 2022 .

Interleukin‐6 in transcatheter arterial embolization for patients with hepatocellular carcinoma. Effects of serine protease inhibitor

S. Kawata, S. Kiso, T. Nagase, 1994, Cancer.

3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 1: discovery and exploration of the carboxyamide side chain.

M. Toda, H. Nakai, K. Yoshikawa, 2010, Bioorganic & medicinal chemistry.

3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. part 2: optimization of the side chains to improve in vitro and in vivo potencies.

M. Toda, H. Nakai, K. Yoshikawa, 2010, Bioorganic & medicinal chemistry.

Discovery of a series of acrylic acids and their derivatives as chemical leads for selective EP3 receptor antagonists.

M. Toda, H. Nakai, T. Nagase, 2009, Bioorganic & medicinal chemistry.

A case of pediatric primary sclerosing cholangitis.

S. Kawata, S. Tamura, S. Tarui, 1991 .

Synthesis and evaluation of novel modified γ-lactam prostanoids as EP4 subtype-selective agonists.

M. Toda, T. Maruyama, T. Maruyama, 2012, Bioorganic & medicinal chemistry.

Analyses of polypeptides in the liver of a novel mutant (LEC rats) to hereditary hepatitis and hepatoma by two-dimensional gel electrophoresis: identification of P29/6.8 as carbonic anhydrase III and triosephosphate isomerase.

N. Taniguchi, T. Sugiyama, S. Kawata, 1991, Comparative biochemistry and physiology. B, Comparative biochemistry.

Identifications of Carbonic Anhydrase III and Triosephosphate Isomerase in the Liver Proteins in LEC Rats on Two-Dimensional Gel Electrophoresis

N. Taniguchi, T. Sugiyama, S. Higashiyama, 1991 .

Total synthesis of stevastelins : Structure confirmation of stevastelins B and B3, and structure revision of stevastelin C3

T. Nagase, N. Chida, Kazuo Kurosawa, 2006 .

Discovery of orally active prostaglandin D2 receptor antagonists.

M. Toda, H. Nakai, T. Nagase, 2004, Bioorganic & medicinal chemistry letters.