Joseph S Takahashi

发表

cAMP-Dependent Signaling as a Core Component of the Mammalian Circadian Pacemaker

J. Takahashi, E. Maywood, M. Hastings, 2008, Science.

Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1

Dina Schneidman-Duhovny, Greg L. Hura, Greg L Hura, 2017, Proceedings of the National Academy of Sciences.

Molecular components of the Mammalian circadian clock.

Ethan D Buhr, J. Takahashi, Ethan D. Buhr, 2013, Handbook of experimental pharmacology.

Rhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanism.

Seung-Hee Yoo, J. Takahashi, Aaron E. Schirmer, 2009, Molecular cell.

Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex

Hong Zhang, Seung-Hee Yoo, J. Takahashi, 2012, Science.

Large-scale mutagenesis of the mouse to understand the genetic bases of nervous system structure and function.

Jay Snoddy, Warren A Kibbe, Dan Goldowitz, 2004, Brain research. Molecular brain research.

Positional Cloning of the Mouse Circadian Clock Gene

Minoru Tanaka, D. P. King, J. Kornhauser, 1997, Cell.

Divergent and nonuniform gene expression patterns in mouse brain

Allan R. Jones, Ed S Lein, Michael J Hawrylycz, 2010, Proceedings of the National Academy of Sciences.

System-Driven and Oscillator-Dependent Circadian Transcription in Mice with a Conditionally Active Liver Clock

Ueli Schibler, Benoît Kornmann, Hermann Bujard, 2007, PLoS biology.

Time- and exercise-dependent gene regulation in human skeletal muscle

Nathan Salomonis, Erin L. McDearmon, Morris Schambelan, 2003, Genome Biology.

A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo.

Ook Joon Yoo, Ethan D Buhr, Seung-Hee Yoo, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Molecular components of the mammalian circadian clock.

J. Takahashi, Caroline H Ko, Joseph S Takahashi, 2006, Human molecular genetics.

Locomotor response to an open field during C57BL/6J active and inactive phases differences dependent on conditions of illumination

Orfeu M Buxton, J. Takahashi, A. Chang, 2000, Physiology & Behavior.

Functional Identification of the Mouse Circadian Clock Gene by Transgenic BAC Rescue

Anne-Marie Chang, D. P. King, J. Takahashi, 1997, Cell.

The orphan receptor Rev-erbalpha gene is a target of the circadian clock pacemaker.

Gérard Triqueneaux, Vincent Laudet, Franck Delaunay, 2004, Journal of molecular endocrinology.

Dissecting the Functions of the Mammalian Clock Protein BMAL1 by Tissue-Specific Rescue in Mice

Erin L. McDearmon, Hee-Kyung Hong, Jacqueline A Walisser, 2006, Science.

Second-generation high-throughput forward genetic screen in mice to isolate subtle behavioral mutants

J. Takahashi, H. Hong, Vivek Kumar, 2011, Proceedings of the National Academy of Sciences.

Suprachiasmatic nucleus: cell autonomy and network properties.

David K Welsh, D. Welsh, S. Kay, 2010, Annual review of physiology.

Finding New Clock Components: Past and Future

J. Takahashi, Joseph S Takahashi, 2004, Journal of biological rhythms.

CLOCK and BMAL1 regulate MyoD and are necessary for maintenance of skeletal muscle phenotype and function

Kenneth S Campbell, Erin L. McDearmon, Brenda Russell, 2010, Proceedings of the National Academy of Sciences.

The mouse Clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase-response curve amplitude.

Anne-Marie Chang, Ethan D Buhr, J. Takahashi, 2006, Proceedings of the National Academy of Sciences of the United States of America.

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues.

Ook Joon Yoo, Hee-Kyung Hong, Ethan D Buhr, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Photic and circadian expression of luciferase in mPeriod1-luc transgenic mice in vivo

Erik D Herzog, Edward W. Spitznagel, Gene Block, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex

Shannon N Nangle, Nobuya Koike, Hajime Tei, 2014, eLife.

BK calcium-activated potassium channels regulate circadian behavioral rhythms and pacemaker output

Richard W Aldrich, B. H. Miller, R. Aldrich, 2006, Nature Neuroscience.

In vivo single-cell detection of metabolic oscillations in stem cells.

Enrico Gratton, Chiara Stringari, Bogi Andersen, 2015, Cell reports.

Mammalian circadian biology: elucidating genome-wide levels of temporal organization.

J. Takahashi, P. Lowrey, Joseph S Takahashi, 2004, Annual review of genomics and human genetics.

Methods to record circadian rhythm wheel running activity in mice.

J. Takahashi, Joseph S Takahashi, Sandra M Siepka, 2005, Methods in enzymology.

Circadian transcriptional output in the SCN and liver of the mouse.

Satchidananda Panda, Steve Kay, S. Kay, 2003, Novartis Foundation symposium.

Hepatocyte circadian clock controls acetaminophen bioactivation through NADPH-cytochrome P450 oxidoreductase

Brian E. McIntosh, Erin L. McDearmon, Yan Liu, 2014, Proceedings of the National Academy of Sciences.

Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex.

J. Takahashi, M. Antoch, Renliang Zhang, 2005, Proceedings of the National Academy of Sciences of the United States of America.