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H. Hirasawa, K. Matsuda, T. Moriguchi, 2003, Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.

Relationship between the 4Ts scoring system and the antiplatelet factor 4/heparin antibodies test in critically ill patients

S. Oda, T. Nakada, Y. Matsumura, 2014, Acute medicine & surgery.

N. Takeyama, T. Hifumi, S. Kushimoto, 2022, Scientific Reports.

A CO2 removal system using extracorporeal lung and renal assist device with an acid and alkaline infusion

O. Nishida, S. Oda, K. Moriyama, 2019, Journal of Artificial Organs.

Private residence as a location of cardiac arrest may have a deleterious effect on the outcomes of out-of-hospital cardiac arrest in patients with an initial non-shockable cardiac rhythm: A multicentre retrospective cohort study.

T. Tagami, Keita Shibahashi, K. Sugiyama, 2020, Resuscitation.

Heart Rate and Mortality After Resuscitation in Patients With Out-of-Hospital Cardiac Arrest　- Insights From the SOS-KANTO Registry.

T. Tagami, R. Nakanishi, M. Takeda, 2022, Circulation journal : official journal of the Japanese Circulation Society.

Delayed aortic regurgitation due to traumatic pseudoaneurysm of the sinus of Valsalva

S. Oda, T. Nakada, Nozomi Takahashi, 2019, Acute medicine & surgery.

External validation of simplified out-of-hospital cardiac arrest and cardiac arrest hospital prognosis scores in a Japanese population: a multicentre retrospective cohort study

T. Tagami, Keita Shibahashi, K. Sugiyama, 2020, Emergency Medicine Journal.

Possibility of deterioration of respiratory status when steroids precede antiviral drugs in patients with COVID-19 pneumonia: A retrospective study

S. Sakao, T. Nakada, H. Kasai, 2021, PloS one.

Accuracy for Mortality Prediction With Additive Biomarkers Including Interleukin-6 in Critically Ill Patients: A Multicenter Prospective Observational Study

K. Matsuda, T. Moriguchi, J. Sasaki, 2020, Critical care explorations.

Case Report: Sustained mitochondrial damage in cardiomyocytes in patients with severe propofol infusion syndrome.

Yoshio Kobayashi, S. Oda, T. Nakada, 2020, F1000Research.

Case Report: Sustained mitochondrial damage in cardiomyocytes in patients with severe propofol infusion syndrome

S. Oda, T. Nakada, H. Takano, 2022, F1000Research.

Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike

K. Ishii, J. Zahradník, M. Seki, 2022, Cell.

Prediction algorithm for ICU mortality and length of stay using machine learning

Eiryo Kawakami, T. Nakada, Tadanaga Shimada, 2021, Scientific Reports.

The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

M. Kanai, Y. Okada, S. Fuke, 2022, Nature Communications.

Temporal trends of medical cost and cost-effectiveness in sepsis patients: a Japanese nationwide medical claims database

K. Fushimi, N. Shime, Y. Umemura, 2022, Journal of Intensive Care.

Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2–induced lung exudative vasculitis and predicts COVID-19 severity

T. Tsukamoto, I. Yoshino, K. Yokote, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Significance of lactate clearance in septic shock patients with high bilirubin levels

K. Walley, J. Russell, T. Nakada, 2020, Scientific Reports.

Effects of tranexamic acid on coagulofibrinolytic markers during the early stage of severe trauma: A propensity score–matched analysis

N. Takeyama, S. Kushimoto, S. Fujishima, 2022, Medicine.

Interhospital transportation of a COVID-19 patient undergoing veno-venous extracorporeal membrane oxygenation by helicopter

T. Nakada, R. Abe, N. Hattori, 2020, The American Journal of Emergency Medicine.

Disseminated intravascular coagulation immediately after trauma predicts a poor prognosis in severely injured patients

N. Takeyama, T. Hifumi, S. Kushimoto, 2021, Scientific Reports.

Prehospital lactate improves prediction of the need for immediate interventions for hemorrhage after trauma

Hiroaki Watanabe, T. Matsuoka, T. Aizimu, 2019, Scientific Reports.

AA genotype of IL‐8 −251A/T is associated with low PaO2/FiO2 in critically ill patients and with increased IL‐8 expression

K. Walley, J. Russell, P. Wacharasint, 2012, Respirology.

This information is current as in Septic Shock MortalityInducing Kinase Is Associated with B κ A Single Nucleotide Polymorphism in NF -

M. McConechy, K. Walley, J. Boyd, 2011 .

DOCK2 is involved in the host genetics and biology of severe COVID-19

M. Kanai, Y. Kamatani, Y. Okada, 2022, Nature.

Shortening of low-flow duration over time was associated with improved outcomes of extracorporeal cardiopulmonary resuscitation in in-hospital cardiac arrest

S. Oda, T. Nakada, K. Shinozaki, 2020, Journal of Intensive Care.

Development of a novel information and communication technology system to compensate for a sudden shortage of emergency department physicians

Kumiko Tanaka, T. Matsuoka, H. Fukuma, 2017, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

Prehospital ABC (Age, Bystander and Cardiogram) scoring system to predict neurological outcomes of cardiopulmonary arrest on arrival: post hoc analysis of a multicentre prospective observational study

M. Yasutake, T. Tagami, H. Yokota, 2022, Emergency Medicine Journal.

Characteristics and outcomes of frail patients with suspected infection in intensive care units: a descriptive analysis from a multicenter cohort study

N. Takeyama, T. Hifumi, S. Kushimoto, 2020, BMC Geriatrics.

Disseminated Intravascular Coagulation Immediately after Trauma Predicts a Poor Prognosis in Severely Injured Patients: A Sub-analysis of a Multicenter Prospective Study on Disseminated Intravascular Coagulation in Trauma

N. Takeyama, T. Hifumi, S. Kushimoto, 2020 .

mRNA induces RANTES production in trophoblast cells via TLR3 only when delivered intracellularly using lipid membrane encapsulation.

M. McConechy, P. von Dadelszen, J. Boyd, 2011, Placenta.

Prehospital diagnostic algorithm for acute coronary syndrome using machine learning: a prospective observational study

Yoshio Kobayashi, T. Nakada, R. Abe, 2022, Scientific Reports.

Demographics, Treatments, and Outcomes of Acute Respiratory Distress Syndrome: The Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis, and Trauma (Forecast) Study.

N. Takeyama, T. Hifumi, S. Kushimoto, 2020, Shock.

Impact of increased calls to rapid response systems on unplanned ICU admissions: Japanese database study.

S. Oda, S. Fujitani, T. Nakada, 2019, The American journal of emergency medicine.

Omeprazole-associated rhabdomyolysis

Kumiko Tanaka, S. Oda, T. Nakada, 2014, Critical Care.

Elevated oxygen demand in a case of COVID-19 with severe ARDS: a point for optimal oxygenation therapy including ECMO management

T. Oshima, S. Sakao, T. Nakada, 2020 .

Treatment of severe sepsis and septic shock by CHDF using a PMMA membrane hemofilter as a cytokine modulator.

H. Hirasawa, S. Oda, Masataka Nakamura, 2010, Contributions to nephrology.

Serum levels of tau protein increase according to the severity of the injury in DAI rat model

T. Oshima, S. Oda, T. Nakada, 2020, F1000Research.

Ineffective neutralization of the SARS-CoV-2 Mu variant by convalescent and vaccine sera

A. Kaneda, S. Nakagawa, Kei Sato, 2021, bioRxiv.

Results of the 2018 Japan Society for Blood Purification in Critical Care survey: current status and outcomes

O. Nishida, T. Moriguchi, H. Shiga, 2022, Renal Replacement Therapy.

Diagnostic Accuracy of Biomarkers for Early Multiple Organ Dysfunction in Critically Ill Patients: A Multicenter Prospective Observational Study

K. Matsuda, T. Moriguchi, J. Sasaki, 2020 .

Short- versus long-course antibiotic therapy for sepsis: a post hoc analysis of the nationwide cohort study

K. Fushimi, N. Shime, T. Abe, 2022, Journal of Intensive Care.

Early Elevation of Cell-free DNA After Acute Mesenteric Ischemia in Rats.

T. Miyasho, T. Oshima, S. Oda, 2021, The Journal of surgical research.

Characteristics of hospitalized patients with COVID-19 during the first to fifth waves of infection: a report from the Japan COVID-19 Task Force

M. Kanai, Y. Okada, S. Fuke, 2022, BMC infectious diseases.

Acquisition and Analysis of Microcirculation Image in Septic Model Rats

H. Haneishi, S. Oda, Kazuya Nakano, 2022, Sensors.

Normal-Range Blood Lactate Concentration in Septic Shock Is Prognostic and Predictive

Taka-aki Nakada, John H Boyd, James A Russell, 2012, Shock.

Hour-1 bundle adherence was associated with reduction of in-hospital mortality among patients with sepsis in Japan

N. Takeyama, T. Hifumi, S. Kushimoto, 2021, PloS one.

Blood purification for hypercytokinemia.

H. Hirasawa, K. Matsuda, S. Oda, 2006, Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.

Estimation of Blood Oxygen Saturation in the Circulation Circuit for Extracorporeal Membrane Oxygenation

Kazuya Nakano, Hideaki Haneishi, Takashi Ohnishi, 2019, IEEE Access.

Median arcuate ligament syndrome presenting as hemorrhagic shock.

S. Oda, T. Nakada, N. Hattori, 2013, The American journal of emergency medicine.

A Single Nucleotide Polymorphism in NF-κB Inducing Kinase Is Associated with Mortality in Septic Shock

M. McConechy, K. Walley, J. Russell, 2011, The Journal of Immunology.

Efficacy of Continuous Hemodiafiltration for Patients with Congestive Heart Failure

H. Hirasawa, S. Oda, H. Shiga, 2002, Blood Purification.

Implementation of earlier antibiotic administration in patients with severe sepsis and septic shock in Japan: a descriptive analysis of a prospective observational study

G. Phillips, H. Okudera, A. Rhodes, 2019, Critical Care.

Impact of Body Temperature Abnormalities on the Implementation of Sepsis Bundles and Outcomes in Patients With Severe Sepsis: A Retrospective Sub-Analysis of the Focused Outcome Research on Emergency Care for Acute Respiratory Distress Syndrome, Sepsis and Trauma Study

N. Takeyama, T. Hifumi, S. Kushimoto, 2019, Critical care medicine.

Treatment of Septic Shock with Continuous HDF Using 2 PMMA Hemofilters for Enhanced Intensity

H. Hirasawa, T. Oshima, S. Oda, 2012, The International journal of artificial organs.

Correlation between high blood IL-6 level, hyperglycemia, and glucose control in septic

H. Hirasawa, S. Oda, Masataka Nakamura, 2012 .

Fluid resuscitation in septic shock: A positive fluid balance and elevated central venous pressure are associated with increased mortality*

Taka-aki Nakada, Jason Forbes, K. Walley, 2011, Critical care medicine.

H. Hirasawa, K. Matsuda, S. Oda, 2004, The Journal of trauma.

Sepsis decreases lung SVEP1 expression in a murine model

K. Sekiguchi, M. Hatano, T. Nakada, 2023, F1000Research.

Genetic Polymorphisms in Sepsis and Cardiovascular Disease: Do Similar Risk Genes Suggest Similar Drug Targets?

K. Walley, J. Russell, E. Nakada, 2019, Chest.

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)

M. Egi, S. Taito, N. Shime, 2021, Journal of Intensive Care.

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016)

A. Matsuda, M. Egi, N. Shime, 2018, Journal of Intensive Care.

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J‐SSCG 2016)

A. Matsuda, M. Egi, N. Shime, 2018, Acute medicine & surgery.

Mapping the human genetic architecture of COVID-19

Mattia G. Bergomi, Christopher M. DeBoever, Matthew A. Wiles, 2021, Nature.

Outcome prediction in sepsis combined use of genetic polymorphisms - A study in Japanese population.

H. Uno, T. Tokuhisa, H. Hirasawa, 2011, Cytokine.

Detecting time-evolving phenotypic components of adverse reactions against BNT162b2 SARS-CoV-2 vaccine via non-negative tensor factorization

T. Shimamura, Eiryo Kawakami, H. Hanaoka, 2022, iScience.

Japan COVID-19 Task Force: a nation-wide consortium to elucidate host genetics of COVID-19 pandemic in Japan

M. Kanai, Y. Okada, S. Fuke, 2021, medRxiv.

Serum Procalcitonin Level and SOFA Score at Discharge from the Intensive Care Unit Predict Post-Intensive Care Unit Mortality: A Prospective Study

T. Oshima, S. Oda, T. Nakada, 2014, PloS one.

Virological characteristics of SARS-CoV-2 BA.2 variant

J. Zahradník, A. Kaneda, M. Seki, 2022, bioRxiv.

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J‐SSCG 2020)

M. Egi, S. Taito, N. Shime, 2021, Acute medicine & surgery.

Veno-venous extracorporeal membrane oxygenation (ECMO) for acute respiratory failure caused by liver abscess

T. Matsuoka, T. Nakada, K. Idoguchi, 2015, Journal of Artificial Organs.

Usefulness of interleukin 6 levels in the cerebrospinal fluid for the diagnosis of bacterial meningitis.

Kumiko Tanaka, S. Oda, T. Nakada, 2014, Journal of critical care.

Cardiac arrest due to airway obstruction in hereditary angioedema.

T. Matsuoka, T. Nakada, Y. Mizushima, 2015, The American journal of emergency medicine.

Novel information and communication technology system to improve surge capacity and information management in the initial hospital response to major incidents.

Eiji Hira, T. Matsuoka, T. Nakada, 2019, The American journal of emergency medicine.

TNFAIP2 Inhibits Early TNFa-Induced NF-κB Signaling and Decreases Survival in Septic Shock Patients

M. Wurfel, C. Fjell, K. Walley, 2015, Journal of Innate Immunity.

A Nonsynonymous Polymorphism of IRAK4 Associated with Increased Prevalence of Gram-Positive Infection and Decreased Response to Toll-Like Receptor Ligands

M. Wurfel, K. Walley, J. Russell, 2011, Journal of Innate Immunity.

Current Spectrum of Causative Pathogens in Sepsis: A Prospective Nationwide Cohort Study in Japan.

N. Takeyama, T. Hifumi, S. Kushimoto, 2020, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

Cytomegalovirus infection in immunocompetent critically ill patients

S. Oda, T. Nakada, M. Takeda, 2019, Journal of the Japanese Society of Intensive Care Medicine.

Suspected cholestatic liver injury induced by favipiravir in a patient with COVID-19

T. Nakada, I. Ishii, Misa Sayama, 2020, Journal of Infection and Chemotherapy.

Case Report: Urgent endovascular treatment of subclavian artery injury after blunt trauma

T. Matsuoka, H. Fukuma, T. Nakada, 2014, F1000Research.

Decreased total iron binding capacity upon intensive care unit admission predicts red blood cell transfusion in critically ill patients

S. Oda, T. Nakada, R. Abe, 2019, PloS one.

PCSK9 is a critical regulator of the innate immune response and septic shock outcome

M. Reilly, C. Fjell, J. Ferguson, 2014, Science Translational Medicine.

Interleukin-6 Levels Act as a Diagnostic Marker for Infection and a Prognostic Marker in Patients with Organ Dysfunction in Intensive Care Units

S. Oda, T. Nakada, W. Takahashi, 2016, Shock.

Veno-arterial extracorporeal membrane oxygenation for Streptococcus pyogenes toxic shock syndrome in pregnancy

S. Oda, T. Nakada, R. Abe, 2016, Journal of Artificial Organs.

Neutralization of the SARS-CoV-2 Mu Variant by Convalescent and Vaccine Serum

A. Kaneda, S. Nakagawa, A. Takaori-Kondo, 2021, The New England journal of medicine.

Association between increased blood interleukin-6 levels on emergency department arrival and prolonged length of intensive care unit stay for blunt trauma

T. Matsuoka, T. Nakada, K. Shinozaki, 2016, World Journal of Emergency Surgery.

Influence of toll-like receptor 4, CD14, tumor necrosis factor, and interleukine-10 gene polymorphisms on clinical outcome in Japanese critically ill patients.

M. Hatano, T. Tokuhisa, H. Hirasawa, 2005, The Journal of surgical research.

Differential pattern of cell-surface and soluble TREM-1 between sepsis and SIRS.

H. Hirasawa, S. Oda, Masataka Nakamura, 2013, Cytokine.

A common polymorphism in the 5' region of the human protein c gene binds USF1.

K. Walley, J. Russell, Katherine R. Thain, 2012, Thrombosis research.

Continuous Hemodiafiltration with PMMA Hemofilter in the Treatment of Patients with Septic Shock

H. Hirasawa, K. Matsuda, S. Oda, 2008, Molecular medicine.

Leucyl/cystinyl aminopeptidase gene variants in septic shock.

H. Hirasawa, K. Walley, J. Russell, 2011, Chest.

beta2-Adrenergic receptor gene polymorphism is associated with mortality in septic shock.

K. Walley, J. Russell, Katherine R. Thain, 2010, American journal of respiratory and critical care medicine.

VPS13D Gene Variant Is Associated with Altered IL-6 Production and Mortality in Septic Shock

Mark D. Wilkinson, M. McConechy, C. Fjell, 2015, Journal of Innate Immunity.

Blood Interleukin-6 Levels Predict Multiple Organ Dysfunction in Critically Ill Patients

K. Matsuda, T. Moriguchi, J. Sasaki, 2020, Shock.

Association between male sex and increased mortality after falls.

T. Matsuoka, T. Nakada, Shota Nakao, 2015, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

Identifying Sepsis Populations Benefitting from Anticoagulant Therapy: A Prospective Cohort Study Incorporating a Restricted Cubic Spline Regression Model

N. Takeyama, T. Hifumi, S. Kushimoto, 2019, Thrombosis and Haemostasis.

Variations in infection sites and mortality rates among patients in intensive care units with severe sepsis and septic shock in Japan

H. Okudera, Kenichi Yoshida, N. Takeyama, 2019, Journal of Intensive Care.

Proteome analysis of hemofilter adsorbates to identify novel substances of sepsis: a pilot study

F. Nomura, S. Oda, M. Satoh, 2017, Journal of Artificial Organs.

Mortality analysis among sepsis patients in and out of intensive care units using the Japanese nationwide medical claims database: a study by the Japan Sepsis Alliance study group

K. Fushimi, N. Shime, Y. Umemura, 2023, Journal of Intensive Care.

Epidemiology of sepsis and septic shock in intensive care units between sepsis-2 and sepsis-3 populations: sepsis prognostication in intensive care unit and emergency room (SPICE-ICU)

N. Takeyama, T. Hifumi, S. Kushimoto, 2020, Journal of Intensive Care.

Characteristics, management, and in-hospital mortality among patients with severe sepsis in intensive care units in Japan: the FORECAST study

H. Okudera, N. Takeyama, T. Hifumi, 2018, Critical Care.

Risk prediction of biomarkers for early multiple organ dysfunction in critically ill patients

K. Matsuda, T. Moriguchi, J. Sasaki, 2021, BMC Emergency Medicine.

Prognostic Accuracy of Quick SOFA is different according to the severity of illness in infectious patients.

N. Takeyama, T. Hifumi, S. Kushimoto, 2019, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Subsequent shock deliveries are associated with increased favorable neurological outcomes in cardiac arrest patients who had initially non-shockable rhythms

N. Yonemoto, N. Morimura, A. Yaguchi, 2015, Critical Care.

Trends in the incidence and outcome of sepsis using data from a Japanese nationwide medical claims database-the Japan Sepsis Alliance (JaSA) study group-

K. Fushimi, N. Shime, Y. Umemura, 2021, Critical Care.

IL17A genetic variation is associated with altered susceptibility to Gram-positive infection and mortality of severe sepsis

K. Walley, J. Russell, J. Boyd, 2011, Critical care.

Nighttime is associated with decreased survival and resuscitation efforts for out-of-hospital cardiac arrests: a prospective observational study

N. Yonemoto, T. Tagami, N. Morimura, 2016, Critical Care.

Antibody responses to BNT162b2 mRNA COVID-19 vaccine and their predictors among healthcare workers in a tertiary referral hospital in Japan

A. Kaneda, H. Matsubara, I. Yoshino, 2021, Clinical Microbiology and Infection.

Characteristics and outcomes of bacteremia among ICU-admitted patients with severe sepsis

H. Okudera, Kenichi Yoshida, N. Takeyama, 2020, Scientific Reports.

H. Hirasawa, K. Matsuda, S. Oda, 2004, Blood Purification.

Identification of a Nonsynonymous Polymorphism in the SVEP1 Gene Associated With Altered Clinical Outcomes in Septic Shock*

K. Walley, J. Russell, J. Boyd, 2015, Critical care medicine.

Genetic polymorphisms in sepsis

S. Oda, T. Nakada, Tadanaga Shimada, 2013 .

Association of angiotensin II type 1 receptor-associated protein gene polymorphism with increased mortality in septic shock*

H. Hirasawa, K. Walley, J. Boyd, 2011, Critical care medicine.

Pathophysiology of Coagulopathy Induced by Traumatic Brain Injury Is Identical to That of Disseminated Intravascular Coagulation With Hyperfibrinolysis

N. Takeyama, S. Kushimoto, S. Fujishima, 2021, Frontiers in Medicine.

Protocol to acquire time series data on adverse reactions following vaccination using a smartphone or web-based platform.

Eiryo Kawakami, T. Nakada, Y. Yamao, 2023, STAR protocols.

Development of Noninvasive in Vivo Approach to Assess Vascular Permeability in Inflammation Using Fluorescence Imaging

M. Hatano, S. Oda, T. Nakada, 2017, Shock.

Impact of blood glucose abnormalities on outcomes and disease severity in patients with severe sepsis: An analysis from a multicenter, prospective survey of severe sepsis

N. Takeyama, T. Hifumi, S. Kushimoto, 2020, PloS one.

Identifying Septic Shock Populations Benefitting from Polymyxin B Hemoperfusion: A Prospective Cohort Study Incorporating a Restricted Cubic Spline Regression Model.

N. Takeyama, T. Hifumi, S. Kushimoto, 2020, Shock.

Up-regulation of interleukin-10 mRNA expression in peripheral leukocytes predicts poor outcome and diminished human leukocyte antigen-DR expression on monocytes in septic patients.

M. Hatano, T. Tokuhisa, H. Hirasawa, 2008, The Journal of surgical research.

A prehospital diagnostic algorithm for strokes using machine learning: a prospective observational study

Y Hayashi, T Shimada, N Hattori, 2021, Scientific Reports.

Correlation between high blood IL-6 level, hyperglycemia, and glucose control in septic patients

H. Hirasawa, S. Oda, Masataka Nakamura, 2012, Critical Care.

Changes in atropine use for out-of-hospital cardiac arrest patients with non-shockable rhythm between 2002 and 2012.

N. Yonemoto, T. Tagami, H. Yokota, 2016, Resuscitation.

Risk modifiers of acute respiratory distress syndrome in patients with non-pulmonary sepsis: a retrospective analysis of the FORECAST study

H. Okudera, N. Takeyama, T. Hifumi, 2020, Journal of Intensive Care.

Reduction of unexpected serious adverse events after introducing medical emergency team

T. Oshima, S. Oda, T. Nakada, 2015, Acute medicine & surgery.

The significance of disseminated intravascular coagulation on multiple organ dysfunction during the early stage of acute respiratory distress syndrome.

N. Takeyama, T. Hifumi, S. Kushimoto, 2020, Thrombosis research.

Characteristics and outcomes of bacteremia among ICU-admitted patients with severe sepsis

H. Okudera, Kenichi Yoshida, N. Takeyama, 2020, Scientific Reports.

Epinephrine during resuscitation of traumatic cardiac arrest and increased mortality: a post hoc analysis of prospective observational study

T. Tagami, J. Sasaki, M. Takeda, 2019, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

Validation of National Early Warning Score for predicting 30‐day mortality after rapid response system activation in Japan

Kazuhiro Aoki, S. Fujitani, Kuniyoshi Hayashi, 2021, Acute medicine & surgery.

Prevalence and predictors of direct discharge home following hospitalization of patients with serious adverse events managed by the rapid response system in Japan: a multicenter, retrospective, observational study

A. Nakao, H. Naito, Tsuyoshi Nojima, 2021, Acute medicine & surgery.

A safe procedure for connecting a continuous renal replacement therapy device into an extracorporeal membrane oxygenation circuit

S. Oda, T. Nakada, R. Abe, 2017, Journal of Artificial Organs.

Changes in acute blood purification therapy in critical care: republication of the article published in the Japanese Journal of Artificial Organs

S. Oda, T. Nakada, R. Abe, 2019, Journal of Artificial Organs.

Estimation of Respiratory Rate from Thermography Using Respiratory Likelihood Index

T. Nakaguchi, T. Nakada, R. Abe, 2021, Sensors.

Serum S-100B is superior to neuron-specific enolase as an early prognostic biomarker for neurological outcome following cardiopulmonary resuscitation.

F. Nomura, H. Hirasawa, S. Oda, 2009, Resuscitation.

Adverse effect investigation using application software after vaccination against SARS-CoV-2 for healthcare workers

H. Chiba, T. Nakada, I. Ishii, 2022, Journal of Infection and Chemotherapy.

Population pharmacokinetic analysis of meropenem in critically ill patients with acute kidney injury treated with continuous hemodiafiltration.

S. Oda, T. Nakada, N. Hattori, 2020, Therapeutic drug monitoring.

Incidence and Impact of Dysglycemia in Patients with Sepsis Under Moderate Glycemic Control

N. Takeyama, T. Hifumi, S. Kushimoto, 2021, Shock.

IL-17A rs1974226 GG genotype is associated with increased susceptibility to Gram-positive infection and mortality of severe sepsis

J. Boyd, K. Walley, T. Nakada, 2012, Critical Care.

The IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock

K. Walley, J. Russell, P. Wacharasint, 2018, Journal of Innate Immunity.

Identification of factors affecting meropenem pharmacokinetics in critically ill patients: Impact of inflammation on clearance.

T. Nakada, N. Hattori, I. Ishii, 2021, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Role of disseminated intravascular coagulation in severe sepsis.

H. Okudera, N. Takeyama, T. Hifumi, 2019, Thrombosis research.

Clinical application of cytokine-related gene polymorphism analysis using a newly developed DNA chip in critically ill patients.

T. Tokuhisa, H. Hirasawa, S. Oda, 2009, Clinical biochemistry.

Significance of body temperature in elderly patients with sepsis

H. Okudera, Kenichi Yoshida, N. Takeyama, 2020, Critical Care.

Hyperoxemia during resuscitation of trauma patients and increased intensive care unit length of stay: inverse probability of treatment weighting analysis

N. Takeyama, T. Hifumi, S. Kushimoto, 2021, World Journal of Emergency Surgery.

22: POLYMORPHISM OF ANGIOPOIETIN-1 RS4324901 IS ASSOCIATED WITH INCREASED FLUID OVERLOAD AND MORTALITY OF SEPTIC SHOCK

K. Walley, J. Russell, J. Boyd, 2012 .

H. Imamura, N. Takeyama, T. Hifumi, 2023, Journal of Intensive Care.

A randomized prospective comparison of the Baxter and Modified Brooke formulas for acute burn resuscitation

Hitoshi Yamamura, S. Fujishima, O. Tasaki, 2021, Burns Open.

Optimal pressing strength and time for capillary refilling time

Toshiya Nakaguchi, Shigeto Oda, Hideaki Haneishi, 2019, Critical Care.

Prehospital stroke-scale machine-learning model predicts the need for surgical intervention

Y. Iwadate, Y. Yoshida, T. Nakada, 2023, Scientific reports.

Fluid resuscitation in septic shock: A positive fluid balance and elevated central venous pressure are associated with increased mortality*

K. Walley, J. Russell, J. Boyd, 2011 .

Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike

K. Ishii, J. Zahradník, M. Seki, 2022, Cell.

Mapping the human genetic architecture of COVID-19

Mattia G. Bergomi, Christopher M. DeBoever, Matthew A. Wiles, 2021, Nature.

Association between serum levels of interleukin-6 on ICU admission and subsequent outcomes in critically ill patients with acute kidney injury

T. Oshima, T. Aizimu, S. Oda, 2019 .

Association between serum levels of interleukin-6 on ICU admission and subsequent outcomes in critically ill patients with acute kidney injury

T. Oshima, T. Aizimu, S. Oda, 2019, BMC Nephrology.

Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity

M. Kanai, Y. Okada, S. Fuke, 2023, Nature Genetics.

Predictors of severe sepsis-related in-hospital mortality based on a multicenter cohort study

N. Takeyama, T. Hifumi, S. Kushimoto, 2021, Medicine.

The Japanese Clinical Practice Guideline for acute kidney injury 2016

T. Fukui, K. Iseki, Y. Yuzawa, 2018, Journal of Intensive Care.

History of diabetes may delay antibiotic administration in patients with severe sepsis presenting to emergency departments

N. Takeyama, T. Hifumi, Takehiro Sugiyama, 2020, Medicine.

Interleukin‐6 as a diagnostic marker for infection in critically ill patients: A systematic review and meta‐analysis

Masahiro Yoshida, T. Aizimu, S. Oda, 2019, The American journal of emergency medicine.

Efficient CO2 removal using extracorporeal lung and renal assist device

S. Oda, T. Nakada, Nozomi Takahashi, 2018, Journal of Artificial Organs.

A second update on mapping the human genetic architecture of COVID-19

M. A. Hakim Newton, Jack D. Sanders, Jonathan H. Morgan, 2022, Nature.

Association between low body mass index and increased 28-day mortality of severe sepsis in Japanese cohorts

H. Okudera, N. Takeyama, T. Hifumi, 2021, Scientific Reports.

Very Low Density Lipoprotein Receptor Sequesters Lipopolysaccharide Into Adipose Tissue During Sepsis.

H. Hirasawa, K. Walley, J. Russell, 2019, Critical care medicine.

Extremely severe anaemia in a critically ill patient who declined a blood transfusion

S. Oda, T. Nakada, R. Abe, 2015, Transfusion medicine.

Associations between fluid overload and outcomes in critically ill patients with acute kidney injury: a retrospective observational study

T. Nakada, Tadanaga Shimada, Takashi Shimazui, 2023, Scientific reports.

Serum levels of interleukin‐6 may predict organ dysfunction earlier than SOFA score

S. Oda, T. Nakada, Y. Matsumura, 2017, Acute medicine & surgery.

AA genotype of IL‐8 −251A/T is associated with low PaO2/FiO2 in critically ill patients and with increased IL‐8 expression

K. Walley, J. Russell, P. Wacharasint, 2012, Respirology.

Intrahospital transport of mechanically ventilated intensive care patients using new equipment attached to a transfer board

S. Oda, T. Nakada, Y. Matsumura, 2015, Acute medicine & surgery.

Leucyl/cystinyl aminopeptidase gene variants in septic shock.

H. Hirasawa, K. Walley, J. Russell, 2011, Chest.

Changes in acute blood purification therapy in critical care: republication of the article published in the Japanese Journal of Artificial Organs

S. Oda, T. Nakada, R. Abe, 2019, Journal of Artificial Organs.

Superiority of Supervised Machine Learning on Reading Chest X-Rays in Intensive Care Units

T. Nakaguchi, H. Yokota, T. Nakada, 2021, Frontiers in Medicine.

An epidemiological assessment of choking-induced out-of-hospital cardiac arrest: A post hoc analysis of the S OS-KANTO 2012 study.

T. Tagami, M. Takeda, N. Kitamura, 2022, Resuscitation.

beta2-Adrenergic receptor gene polymorphism is associated with mortality in septic shock.

M. McConechy, K. Walley, J. Russell, 2010, American journal of respiratory and critical care medicine.

Fibromuscular dysplasia presenting as hemorrhagic shock due to spontaneous rupture of a right gastroepiploic artery aneurysm.

T. Matsuoka, T. Nakada, K. Idoguchi, 2016, The American journal of emergency medicine.

Validation of semi-automatic citation screening software for creating clinical practice guidelines

N. Shime, T. Nakada, M. Sakuraya, 2022, medRxiv.

Machine learning algorithms for predicting days of high incidence for out-of-hospital cardiac arrest

T. Nakada, K. Shinozaki, Tadanaga Shimada, 2023, Scientific reports.

Investigation into Effect of Thrombomodulin Alfa for Septic Model Rats based on Microcirculation Image Analysis

Hideaki Haneishi, Takashi Ohnishi, Masashi Sekine, 2020, 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).

Prediction of the neurological outcomes post-cardiac arrest: A prospective validation of the CAST and rCAST.

M. Nishikimi, T. Nakada, S. Ohshimo, 2023, The American journal of emergency medicine.

Incidence and mortality of community-acquired and nosocomial infections in Japan: a nationwide medical claims database study

T. Nakada, Nozomi Takahashi, Y. Yamao, 2024, BMC infectious diseases.

Association between hospital spending and in-hospital mortality of patients with sepsis based on a Japanese nationwide medical claims database study

K. Fushimi, T. Abe, T. Aizimu, 2023, Heliyon.

COAGULOPATHY PARAMETERS PREDICTIVE OF OUTCOMES IN SEPSIS-INDUCED ACUTE RESPIRATORY DISTRESS SYNDROME: A SUBANALYSIS OF THE TWO PROSPECTIVE MULTICENTER COHORT STUDIES

N. Takeyama, T. Hifumi, S. Kushimoto, 2023, Shock.

Usefulness of interleukin 6 levels in the cerebrospinal fluid for the diagnosis of bacterial meningitis.

Kumiko Tanaka, S. Oda, T. Nakada, 2014, Journal of critical care.

Efficacy of therapeutic drug monitoring-based antibiotic regimen in critically ill patients: a systematic review and meta-analysis of randomized controlled trials

M. Egi, T. Nakada, Yutaka Kondo, 2023, Journal of Intensive Care.