John C. Williams

发表

Activating mutations of STAT5B and STAT3 in lymphomas derived from gamma delta-T or NK cells

Can Alkan, Kai Fu, Javeed Iqbal, 2022 .

Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.

Roger E. Moore, Jeremy D. King, D. Colcher, 2018, Bioconjugate chemistry.

Magic-angle-spinning NMR structure of the kinesin-1 motor domain assembled with microtubules reveals the elusive neck linker orientation

A. Gronenborn, T. Polenova, John C. Williams, 2022, Nature Communications.

Resonance Assignments and Secondary Structure Analysis of Dynein Light Chain 8 by Magic Angle Spinning NMR Spectroscopy.

Shangjin Sun, T. Polenova, Sivakumar Paramasivam, 2011, Canadian journal of chemistry.

The dynein light chain 8 binding motif of rabies virus phosphoprotein promotes efficient viral transcription

M. Schnell, G. Tan, John C. Williams, 2007, Proceedings of the National Academy of Sciences.

Dynein: An ancient motor protein involved in multiple modes of transport.

R. Vallee, John C Williams, Dileep Varma, 2004, Journal of neurobiology.

Crystal Structure of Human SCO1

E. Schon, W. Hendrickson, D. Glerum, 2005, Journal of Biological Chemistry.

Crystal Structure of Dynein Light Chain TcTex-1*

W. Hendrickson, John C. Williams, Hui Xie, 2005, Journal of Biological Chemistry.

Nature’s design – a blueprint for engineered therapeutic antibodies

U. Rodeck, John C. Williams, 2008, Cancer biology & therapy.

Meditope–Fab interaction: threading the hole

John C Williams, K. Avery, John C. Williams, 2017, Acta crystallographica. Section F, Structural biology communications.

L1CAM is an independent predictor of poor survival in endometrial cancer - An analysis of The Cancer Genome Atlas (TCGA).

C. Ouyang, C. Warden, John C. Williams, 2016, Gynecologic oncology.

Atomic-resolution structure of the CAP-Gly domain of dynactin on polymeric microtubules determined by magic angle spinning NMR spectroscopy

T. Polenova, Xingyu Lu, John C. Williams, 2015, Proceedings of the National Academy of Sciences.

Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes

P. Bjorkman, Ziyan Wu, John C Williams, 2022, bioRxiv.

The role of the linker between the SH2 domain and catalytic domain in the regulation and function of Src

Giulio Superti‐Furga, G. Superti-Furga, S. Gonfloni, 1997, The EMBO journal.

Structural Analysis of Dynein Intermediate and Light Chains

John C. Williams, C. M. Lightcap, Amanda E. Siglin, 2012 .

The LRF transcription factor regulates mature B cell development and the germinal center response in mice.

S. Tsuzuki, J. Teruya-Feldstein, Y. Ishikawa, 2011, The Journal of clinical investigation.

Identification of multiple potent neutralizing and non-neutralizing antibodies against Epstein-Barr virus gp350 protein with potential for clinical application and as reagents for mapping immunodominant epitopes.

Jinhui Wang, Xiwei Wu, John C Williams, 2019, Virology.

CTLA4 Promotes Tyk2-STAT3-Dependent B-cell Oncogenicity.

Hua Yu, A. Herrmann, T. Blankenstein, 2017, Cancer research.

Functional interaction between dynein light chain and intermediate chain is required for mitotic spindle positioning

J. Cooper, Jeffrey K. Moore, Jun Li, 2011, Molecular biology of the cell.

Internal Dynamics of Dynactin CAP-Gly Is Regulated by Microtubules and Plus End Tracking Protein EB1*

T. Polenova, John C. Williams, Si Yan, 2014, The Journal of Biological Chemistry.

A Platform To Enhance Quantitative Single Molecule Localization Microscopy

Victor A Kenyon, T. Jovanović-Talisman, Eliedonna E. Cacao, 2018, Journal of the American Chemical Society.

Three-dimensional structure of CAP-gly domain of mammalian dynactin determined by magic angle spinning NMR spectroscopy: conformational plasticity and interactions with end-binding protein EB1.

C. Schwieters, T. Polenova, John C. Williams, 2013, Journal of molecular biology.

Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells

Can Alkan, Kai Fu, Javeed Iqbal, 2015, Nature Communications.

Disruption of TWIST1-RELA binding by mutation and competitive inhibition to validate the TWIST1 WR domain as a therapeutic target

C. Glackin, John C. Williams, Cai M. Roberts, 2017, BMC Cancer.

Photocleavable Dimerizer for the Rapid Reversal of Molecular Trap Antagonists*

John C. Williams, D. Horne, Shubbir Ahmed, 2014, The Journal of Biological Chemistry.

Design and development of masked therapeutic antibodies to limit off-target effects: Application to anti-EGFR antibodies

U. Rodeck, John C Williams, C. Kari, 2009, Cancer biology & therapy.

Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development.

Yate-Ching Yuan, R. Jove, N. Vaidehi, 2011, ACS chemical biology.

Activating mutations of STAT 5 B and STAT 3 in lymphomas derived from gdT or NK cells

C. Alkan, L. Staudt, W. Chan, 2015 .

Solid-state NMR spectroscopy of protein complexes.

A. Gronenborn, Shangjin Sun, T. Polenova, 2012, Methods in molecular biology.

Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic MABS C225 and 425

I. Chaiken, U. Rodeck, C. Kari, 2008, Cancer biology & therapy.

Structure of an Arrestin2-Clathrin Complex Reveals a Novel Clathrin Binding Domain That Modulates Receptor Trafficking*

M. von Zastrow, J. Benovic, M. Puthenveedu, 2009, The Journal of Biological Chemistry.

Dynein and Dynactin Leverage Their Bivalent Character to Form a High-Affinity Interaction

M. Poenie, J. Cooper, J. Lear, 2013, PloS one.

RWD Domain as an E2 (Ubc9)-Interaction Module*

Weidong Hu, John C. Williams, Nigus D. Ambaye, 2015, The Journal of Biological Chemistry.

A time-saving strategy for MAS NMR spectroscopy by combining nonuniform sampling and paramagnetic relaxation assisted condensed data collection.

J. Hoch, Shangjin Sun, John C Williams, 2012, The journal of physical chemistry. B.

Solid-state and solution NMR studies of the CAP-Gly domain of mammalian dynactin and its interaction with microtubules.

Shangjin Sun, T. Polenova, John C. Williams, 2009, Journal of the American Chemical Society.

Antibody-based redirection of universal Fabrack-CAR T cells selectively kill antigen bearing tumor cells

Jonathan C. Hibbard, John C Williams, John C. Williams, 2022, Journal for ImmunoTherapy of Cancer.

Mechanically interlocked functionalization of monoclonal antibodies

Jeremy D. King, James W. Puckett, D. Colcher, 2018, Nature Communications.

Biochemical and Structural Characterization of the Pak1-LC8 Interaction*

J. Lear, U. Rodeck, Shangjin Sun, 2008, Journal of Biological Chemistry.

Arylphosphonium salts interact with DNA to modulate cytotoxicity.

John C. Williams, Karen H Almeida, E. Murphy, 2009, Mutation research.

Structural and thermodynamic characterization of a cytoplasmic dynein light chain–intermediate chain complex

Wayne A Hendrickson, Michael C Fitzgerald, R. Vallee, 2007, Proceedings of the National Academy of Sciences.

Observation of an E2 (Ubc9)-homodimer by crystallography

John C Williams, Weidong Hu, John C. Williams, 2016, Data in brief.

Using quantitative single molecule localization microscopy to optimize multivalent HER2-targeting ligands

T. Jovanović-Talisman, Eliedonna E. Cacao, K. Avery, 2023, Frontiers in Medicine.

Development of a High Affinity, Non-covalent Biologic to Add Functionality to Fabs

John C Williams, K. Avery, John C. Williams, 2015, Scientific Reports.

Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies

K. Avery, John C. Williams, D. Horne, 2013, Proceedings of the National Academy of Sciences.

The Crystal Structure of Peroxiredoxin Asp f3 Provides Mechanistic Insight into Oxidative Stress Resistance and Virulence of Aspergillus fumigatus

A. Brakhage, M. Strassburger, T. Heinekamp, 2016, Scientific Reports.

Matrix metalloproteinase-triggered denuding of engineered gold nanoparticles for selective cell uptake.

A. K. Suresh, J. Berlin, John C. Williams, 2013, Journal of materials chemistry. B.

Interaction with LC8 Is Required for Pak1 Nuclear Import and Is Indispensable for Zebrafish Development

Luis E. Arias-Romero, U. Rodeck, John C Williams, 2009, PloS one.

Development and application of in vivo molecular traps reveals that dynein light chain occupancy differentially affects dynein-mediated processes

R. Vallee, Yanqiu Zhao, J. Keen, 2010, Proceedings of the National Academy of Sciences.

Docking study of triphenylphosphonium cations as estrogen receptor alpha modulators.

Joseph P. Salisbury, John C. Williams, 2009 .

The 2.35 A crystal structure of the inactivated form of chicken Src: a dynamic molecule with multiple regulatory interactions.

G. Superti-Furga, S. Gonfloni, A. Weijland, 1997, Journal of molecular biology.

Mechanically interlocked functionalization of monoclonal antibodies

John C Williams, Jeremy D. King, James W. Puckett, 2018, Nature Communications.

The Crystal Structure of Peroxiredoxin Asp f3 Provides Mechanistic Insight into Oxidative Stress Resistance and Virulence of Aspergillus fumigatus

A. Brakhage, M. Strassburger, T. Heinekamp, 2016, Scientific Reports.

Engineering a high-affinity peptide binding site into the anti-CEA mAb M5A

K. Avery, John C. Williams, Gagandeep Singh, 2017, Protein engineering, design & selection : PEDS.

Refining the Quality of Monoclonal Antibodies: Grafting Unique Peptide-Binding Site in the Fab Framework.

Jeremy D. King, John C. Williams, 2018, Methods in molecular biology.