Christopher T. Veldkamp

发表

Recognition of a CXCR4 Sulfotyrosine by the Chemokine Stromal Cell-derived Factor-1α (SDF-1α/CXCL12)

Brian F. Volkman, Thomas P. Sakmar, Christoph Seibert, 2006 .

Polysialylation controls dendritic cell trafficking by regulating chemokine recognition

Karl Mechtler, Brian F. Volkman, Michael Sixt, 2016, Science.

Targeting SDF-1/CXCL12 with a ligand that prevents activation of CXCR4 through structure-based drug design.

B. Volkman, F. Peterson, Christopher T. Veldkamp, 2010, Journal of the American Chemical Society.

The dimeric form of CXCL12 binds to atypical chemokine receptor 1

B. Volkman, F. Peterson, A. Rot, 2021, Science Signaling.

Structural Insights into Molecular Recognition by Human Chemokine CCL19.

B. Volkman, F. Peterson, Yu Chen, 2022, Biochemistry.

CCR7 Sulfotyrosine Enhances CCL21 Binding

B. Volkman, R. Payne, A. Getschman, 2017, International journal of molecular sciences.

Differences in Sulfotyrosine Binding amongst CXCR1 and CXCR2 Chemokine Ligands

B. Volkman, A. Getschman, Christopher T. Veldkamp, 2017, International journal of molecular sciences.

Solution Structure of CCL19 and Identification of Overlapping CCR7 and PSGL-1 Binding Sites.

M. Sixt, F. Peterson, Harley Pyles, 2015, Biochemistry.

Selective Boosting of CCR7-Acting Chemokines; Short Peptides Boost Chemokines with Short Basic Tails, Longer Peptides Boost Chemokines with Long Basic Tails

M. Rosenkilde, B. Volkman, F. Peterson, 2022, International journal of molecular sciences.

Production of Recombinant Chemokines and Validation of Refolding.

Scott K. Johnson, B. Volkman, F. Peterson, 2016, Methods in enzymology.

The monomer–dimer equilibrium of stromal cell‐derived factor‐1 (CXCL 12) is altered by pH, phosphate, sulfate, and heparin

B. Volkman, F. Peterson, Christopher T. Veldkamp, 2005, Protein science : a publication of the Protein Society.

Recognition of a CXCR4 sulfotyrosine by the chemokine stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12).

Christoph Seibert, B. Volkman, F. Peterson, 2006, Journal of molecular biology.

Preparation and Analysis of N-Terminal Chemokine Receptor Sulfopeptides Using Tyrosylprotein Sulfotransferase Enzymes.

T. Sakmar, Christoph Seibert, Christopher T. Veldkamp, 2016, Methods in enzymology.

Sequential tyrosine sulfation of CXCR4 by tyrosylprotein sulfotransferases.

B. Chait, B. Volkman, F. Peterson, 2008, Biochemistry.

Structural Basis of CXCR4 Sulfotyrosine Recognition by the Chemokine SDF-1/CXCL12

Christoph Seibert, B. Volkman, F. Peterson, 2008, Science Signaling.

The solution structure of the forkhead box‐O DNA binding domain of Brugia malayi DAF‐16a

F. Peterson, A. Phillips, Christopher T. Veldkamp, 2014, Proteins.

Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways

N. Heveker, B. Volkman, S. Gravel, 2011, Proceedings of the National Academy of Sciences.

Solution structure of the cold-shock-like protein from Rickettsia rickettsii

J. Koch, F. Peterson, P. G. House, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus

M. Rosenkilde, B. Volkman, F. Vilhardt, 2021, Cellular and Molecular Life Sciences.

Structural basis for chemokine recognition by a G protein–coupled receptor and implications for receptor activation

N. Heveker, N. London, B. Volkman, 2017, Science Signaling.

Crystallographic Structure of Truncated CCL21 and the Putative Sulfotyrosine-Binding Site.

B. Volkman, Emmanuel W Smith, Yu Chen, 2016, Biochemistry.

Transferring the C-terminus of the chemokine CCL21 to CCL19 confers enhanced heparin binding.

Christopher T. Veldkamp, Alex J Griffith, Austin J Barmore, 2016, Biochemical and biophysical research communications.

Monomeric structure of the cardioprotective chemokine SDF‐1/CXCL12

B. Volkman, F. Peterson, Christopher T. Veldkamp, 2009, Protein science : a publication of the Protein Society.

A Versatile Toolkit for Semi-Automated Production of Fluorescent Chemokines to Study CCR7 Expression and Functions

D. Legler, Christopher T. Veldkamp, Marc Artinger, 2021, International journal of molecular sciences.

CCL19 with CCL21‐tail displays enhanced glycosaminoglycan binding with retained chemotactic potency in dendritic cells

M. Rosenkilde, D. Legler, Christopher T. Veldkamp, 2018, Journal of leukocyte biology.

Sulfotyrosine Recognition as Marker for Druggable Sites in the Extracellular Space

B. Volkman, F. Peterson, Christopher T. Veldkamp, 2011, International journal of molecular sciences.

On-column refolding of recombinant chemokines for NMR studies and biological assays.

B. Volkman, F. Peterson, Christopher T. Veldkamp, 2007, Protein expression and purification.

Heparin Oligosaccharides Inhibit Chemokine (CXC Motif) Ligand 12 (CXCL12) Cardioprotection by Binding Orthogonal to the Dimerization Interface, Promoting Oligomerization, and Competing with the Chemokine (CXC Motif) Receptor 4 (CXCR4) N Terminus*

R. Linhardt, B. Volkman, Fuming Zhang, 2012, The Journal of Biological Chemistry.

Solution structure of CCL21 and identification of a putative CCR7 binding site.

F. Peterson, D. McCaslin, Christopher T. Veldkamp, 2012, Biochemistry.

Chemokines in colitis: microRNA control

B. Volkman, Christopher T. Veldkamp, M. Dwinell, 2013, Gut.

NMR indicates the N-termini of PSGL1 and CCR7 bind competitively to the chemokine CCL21

F. Peterson, Christopher T. Veldkamp, A. M. Gray, 2023, Biochemistry and biophysics reports.

Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7

T. Frimurer, M. Rosenkilde, D. Legler, 2019, Front. Immunol..

Chemokines in colitis: microRNA control

B. Volkman, Christopher T. Veldkamp, M. Dwinell, 2013, Gut.

Chemokine Receptor N-Terminus Charge Dictates Reliance on Post-Translational Modifications for Effective Ligand Capture and Following Boosting by Defense Peptides

B. Volkman, F. Peterson, Christopher T. Veldkamp, 2024, International journal of molecular sciences.