Hao Wu

发表

Requirement of Both the Second and Third BIR Domains for the Relief of X-linked Inhibitor of Apoptosis Protein (XIAP)-mediated Caspase Inhibition by Smac*

R. Rich, D. Myszka, Yihua Huang, 2003, Journal of Biological Chemistry.

Anticancer flavonoids are mouse-selective STING agonists.

T. Mitchison, Lingyin Li, Z. Maliga, 2013, ACS chemical biology.

Discovery of MK‐8742: An HCV NS5A Inhibitor with Broad Genotype Activity

Qian Huang, D. Graham, C. Coburn, 2013, ChemMedChem.

A Cell-Based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders.

Weiping Tang, Haibo Xie, Hao Wu, 2020, Cell chemical biology.

Design, synthesis, and biological evaluation of 3-amino-2-oxazolidinone derivatives as potent quorum-sensing inhibitors of Pseudomonas aeruginosa PAO1.

Jun-hai Xiao, Jiahao Yu, Hao Wu, 2020, European journal of medicinal chemistry.

Neuroprotective Effects of 2-Substituted 1, 3-Selenazole Amide Derivatives on Amyloid-Beta-Induced Toxicity in a Transgenic Caenorhabditis Elegans Model of Alzheimer’s Disease

Hao Wu, Kai Jiang, Yuandong Yue, 2021, Neurotoxicity Research.

Synthesis and biological evaluation of FICZ analogues as agonists of aryl hydrocarbon receptor.

R. Peterson, Weiping Tang, G. Winston-McPherson, 2020, Bioorganic & medicinal chemistry letters.

Discovery of 3-morpholino-imidazole[1,5-a]pyrazine BTK inhibitors for rheumatoid arthritis.

T. Fischmann, K. Maloney, C. Garlisi, 2017, Bioorganic & medicinal chemistry letters.

Dual-Reporter System for Real-Time Monitoring of SARS-CoV-2 Main Protease Activity in Live Cells Enables Identification of an Allosteric Inhibition Path

H. Weinstein, R. Schwartz, Xiaohua Duan, 2022, ACS bio & med chem Au.

PHAPI/pp32 Suppresses Tumorigenesis by Stimulating Apoptosis*

Xuejun Jiang, W. Pan, Hao Wu, 2009, Journal of Biological Chemistry.

Discovery of Novel 7-Hydroxy-5-oxo-4,5-dihydrothieno[3,2-b]pyridine-6-carboxamide Derivatives with Potent and Selective Antifungal Activity against Cryptococcus Species.

Lan Yan, Hui Lu, Feng Yang, 2022, Journal of medicinal chemistry.

Discovery of novel BTK inhibitors with carboxylic acids.

T. Fischmann, K. Maloney, C. Garlisi, 2017, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of hydrazone and pyrazoline derivatives derived from androstenedione

Lianmei Zhao, Hao Wu, J. Pei, 2018, Research on Chemical Intermediates.

Design, synthesis, structure-function relationship, bioconversion, and pharmacokinetic evaluation of ertapenem prodrugs.

R. Soll, Hongshi Yu, P. Meinke, 2014, Journal of medicinal chemistry.

Synthesis, biological evaluation, and structure-activity relationship study of novel cytotoxic aza-caffeic acid derivatives.

Y. Lou, Yu Zhao, J. Stöckigt, 2010, Bioorganic & medicinal chemistry.

Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis.

V. Hornak, T. Fischmann, K. Maloney, 2016, ACS medicinal chemistry letters.

Design, synthesis, and evaluation of novel tetrazoles featuring isoxazole moiety as highly selective antifungal agents.

Hao Wu, Liping Li, Da-Zhi Zhang, 2023, European journal of medicinal chemistry.

A Dimeric Smac/Diablo Peptide Directly Relieves Caspase-3 Inhibition by XIAP

Xuejun Jiang, Junru Wang, Yuan Tian, 2007, Journal of Biological Chemistry.

Design, synthesis, and evaluation of novel 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonists.

Yongxin Han, S. Kargman, R. Lobell, 2009, Bioorganic & medicinal chemistry letters.

Development of Selective Histone Deacetylase 6 (HDAC6) Degraders Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase.

Weiping Tang, Hao Wu, Jing Zhang, 2020, ACS medicinal chemistry letters.

Development of the first small molecule histone deacetylase 6 (HDAC6) degraders.

Weiping Tang, Haibo Xie, Yan-ling Song, 2018, Bioorganic & medicinal chemistry letters.

Development of Multi-Functional Histone Deacetylase 6 Degraders with Potent Anti-Myeloma Activity.

Weiping Tang, Haibo Xie, C. Bařinka, 2019, Journal of medicinal chemistry.

Hydrolysis of 2′3′-cGAMP by ENPP1 and design of non-hydrolyzable analogs

T. Mitchison, J. Millán, Lingyin Li, 2014, Nature chemical biology.

Potent, non-covalent reversible BTK inhibitors with 8-amino-imidazo[1,5-a]pyrazine core featuring 3-position bicyclic ring substitutes.

T. Fischmann, K. Maloney, C. Garlisi, 2020, Bioorganic & medicinal chemistry letters.

Corrigendum: Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs.

T. Mitchison, J. Millán, Lingyin Li, 2015, Nature chemical biology.

Erratum: Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs.

T. Mitchison, J. Millán, Lingyin Li, 2015, Nature chemical biology.

A class of allosteric caspase inhibitors identified by high-throughput screening.

Xuejun Jiang, Christophe Antczak, Hakim Djaballah, 2012, Molecular cell.

Design, synthesis, and evaluation of prodrugs of ertapenem.

R. Soll, Hongshi Yu, P. Meinke, 2013, ACS medicinal chemistry letters.