Alexey Rak

发表

Solution structure of the ribosomal RNA binding protein S15 from Thermus thermophilus

Helena Berglund, A. Serganov, H. Berglund, 1997, Nature Structural Biology.

Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents

Thomas Bertrand, Bailin Zhang, Lionel Bert, 2015, Scientific Reports.

Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase.

Herbert Waldmann, Ilme Schlichting, Kirill Alexandrov, 2003, Molecules and Cells.

Chemical biology of protein lipidation: semi-synthesis and structure elucidation of prenylated RabGTPases.

Herbert Waldmann, Luc Brunsveld, Kirill Alexandrov, 2005, Organic & biomolecular chemistry.

NMR structure of bacterial ribosomal protein l20: implications for ribosome assembly and translational control.

M. Springer, M. Garber, A. Rak, 2002, Journal of molecular biology.

The use of virtual screening and differential scanning fluorimetry for the rapid identification of fragments active against MEK1.

Maryse Lowinski, A. Rak, F. Vallée, 2013, Bioorganic & medicinal chemistry letters.

Rab-subfamily-specific regions of Ypt7p are structurally different from other RabGTPases.

Kirill Alexandrov, Roger S Goody, R. Goody, 2002, Structure.

Structure of Rab GDP-Dissociation Inhibitor in Complex with Prenylated YPT1 GTPase

Herbert Waldmann, Susanna Kushnir, Kirill Alexandrov, 2003, Science.

Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule

Dietmar Hoffmann, Jean-Pierre Marquette, Magali Mathieu, 2014, The Journal of Biological Chemistry.

Discovery and optimization of pyrimidone indoline amide PI3Kβ inhibitors for the treatment of phosphatase and tensin homologue (PTEN)-deficient cancers.

Jean-Pierre Marquette, Magali Mathieu, Thomas Bertrand, 2014, Journal of medicinal chemistry.