P. Sonveaux

发表

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice.

Julien Verrax, Bernard Gallez, Pierre Sonveaux, 2008, The Journal of clinical investigation.

Tumor reoxygenation following administration of Mitogen-Activated Protein Kinase inhibitors: a rationale for combination with radiation therapy.

V. Grégoire, J. Verrax, P. Calderon, 2012, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Arterioles : Implications for Cancer Treatment Endothelin-1 Is a Critical Mediator of Myogenic Tone in Tumor

V. Grégoire, J. Balligand, O. Feron, 2004 .

PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing.

K. K. Chereddy, G. Vandermeulen, V. Préat, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Application of Electron Paramagnetic Resonance (EPR) Oximetry to Monitor Oxygen in Wounds in Diabetic Models

P. Porporato, D. Dufrane, B. Gallez, 2015, PloS one.

Common responses of tumors and wounds to hypoxia.

M. Dewhirst, P. Sonveaux, L. Brisson, 2015, Cancer journal.

Evidence of metabolic activity during low-temperature ovarian tissue preservation in different media

M. Dolmans, P. Sonveaux, A. L. Miranda-Vilela, 2020, Journal of Assisted Reproduction and Genetics.

Early reoxygenation in tumors after irradiation: determining factors and consequences for radiotherapy regimens using daily multiple fractions.

V. Grégoire, O. Feron, C. Bouzin, 2005, International journal of radiation oncology, biology, physics.

Hypoxia‐inducible factor 2 alpha impairs human cytotrophoblast syncytialization: New insights into placental dysfunction and fetal growth restriction

P. Baldin, P. Sonveaux, F. Debiève, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Thalidomide radiosensitizes tumors through early changes in the tumor microenvironment.

V. Grégoire, O. Feron, C. Baudelet, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology

F. Bontemps, L. Bertrand, I. Dewachter, 2017, Front. Physiol..

Metabolic and non-metabolic pathways that control cancer resistance to anthracyclines.

P. Sonveaux, Marine C. N. M. Blackman, T. Capeloa, 2020, Seminars in cell & developmental biology.

Combined effects of PLGA and vascular endothelial growth factor promote the healing of non-diabetic and diabetic wounds.

P. Carmeliet, K. K. Chereddy, G. Vandermeulen, 2015, Nanomedicine : nanotechnology, biology, and medicine.

NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment

M. Dewhirst, I. Batinic-Haberle, P. Porporato, 2010, Proceedings of the National Academy of Sciences.

Mitochondrial Alterations (Inhibition of Mitochondrial Protein Expression, Oxidative Metabolism, and Ultrastructure) Induced by Linezolid and Tedizolid at Clinically Relevant Concentrations in Cultured Human HL-60 Promyelocytes and THP-1 Monocytes

P. Tulkens, F. Van Bambeke, P. Sonveaux, 2017, Antimicrobial Agents and Chemotherapy.

Targeting the insulin-like growth factor-1 receptor in human cancer

M. Poirot, P. Sonveaux, 2013 .

MitoQ Inhibits Human Breast Cancer Cell Migration, Invasion and Clonogenicity

M. Murphy, C. Bouzin, P. Porporato, 2022, Cancers.

MitoQ Prevents Human Breast Cancer Recurrence and Lung Metastasis in Mice

C. Bouzin, P. Porporato, F. Duhoux, 2022, Cancers.

Contribution of macrophages in the contrast loss in iron oxide-based MRI cancer cell tracking studies

V. Haufroid, O. Feron, C. Bouzin, 2017, Oncotarget.

Irradiation promotes Akt-targeting therapeutic gene delivery to the tumor vasculature.

O. Feron, C. Bouzin, B. Gallez, 2007, International journal of radiation oncology, biology, physics.

Multiple biological activities of lactic acid in cancer: influences on tumor growth, angiogenesis and metastasis.

P. Porporato, P. Sonveaux, S. Dhup, 2012, Current pharmaceutical design.

Monocarboxylate transporter 1 deficiency impacts CD8+ T lymphocytes proliferation and recruitment to adipose tissue during obesity

N. Mitro, M. Audano, M. Ruscica, 2022, iScience.

Proton channels and exchangers in cancer.

S. Avnet, C. Stock, S. Fais, 2015, Biochimica et biophysica acta.

Cancer-Associated Fibroblasts Promote Prostate Cancer Malignancy via Metabolic Rewiring and Mitochondrial Transfer

E. Giannoni, P. Chiarugi, M. Parri, 2019, bioRxiv.

Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer

E. Giannoni, P. Chiarugi, M. Parri, 2019, bioRxiv.

Energy metabolism in osteoclast formation and activity.

S. Avnet, N. Baldini, N. Zini, 2016, The international journal of biochemistry & cell biology.

Paving the way for therapeutic prevention of tumor metastasis with agents targeting mitochondrial superoxide

P. Porporato, P. Sonveaux, 2015, Molecular & cellular oncology.

Nitric oxide as a radiosensitizer: Evidence for an intrinsic role in addition to its effect on oxygen delivery and consumption

V. Grégoire, O. Feron, C. Dessy, 2004, International journal of cancer.

Nitric oxide-mediated increase in tumor blood flow and oxygenation of tumors implanted in muscles stimulated by electric pulses.

V. Grégoire, O. Feron, B. Gallez, 2003, International journal of radiation oncology, biology, physics.

Insulin increases the sensitivity of tumors to irradiation: involvement of an increase in tumor oxygenation mediated by a nitric oxide-dependent decrease of the tumor cells oxygen consumption.

V. Grégoire, O. Feron, R. Demeure, 2002, Cancer research.

ROS production and angiogenic regulation by macrophages in response to heat therapy

M. Dewhirst, I. Batinic-Haberle, Ž. Vujašković, 2006, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

Selected Endothelial Responses after Ionizing Radiation Exposure Selected Endothelial Responses after Ionizing Radiation Exposure

A. Aerts, Bjorn Baselet, S. Baatout, 2018 .

Clinical and in Vitro Evidence against Placenta Infection at Term by Severe Acute Respiratory Syndrome Coronavirus 2

P. Baldin, O. Danhaive, P. Sonveaux, 2021, The American Journal of Pathology.

Interrogating the lactate dehydrogenase tetramerization site using (stapled) peptides.

T. Copetti, J. Messens, R. Frédérick, 2020, Journal of medicinal chemistry.

Caveolin-1 Expression Is Critical for VEGF-Induced Ischemic Hindlimb Collateralization and Nitric Oxide – Mediated Angiogenesis

V. Grégoire, J. Balligand, O. Feron, 2004 .

Extremely low frequency electromagnetic stimulation reduces ischemic stroke volume by improving cerebral collateral blood flow

C. Dessy, A. Bronckaers, B. Brône, 2022, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Electron paramagnetic resonance as a sensitive tool to assess the iron oxide content in cells for MRI cell labeling studies.

V. Haufroid, O. Feron, R. Muller, 2012, Contrast media & molecular imaging.

Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiation.

P. Courtoy, O. Feron, J. Collet, 2013, Developmental biology.

The Risk of Arterial Thrombosis in Patients With Chronic Myeloid Leukemia Treated With Second and Third Generation BCR-ABL Tyrosine Kinase Inhibitors May Be Explained by Their Impact on Endothelial Cells: An In-Vitro Study

J. Dogné, C. Bouvy, P. Sonveaux, 2020, Frontiers in Pharmacology.

An EPR Study Using Cyclic Hydroxylamines To Assess The Level of Mitochondrial ROS in Superinvasive Cancer Cells

P. Porporato, B. Gallez, P. Sonveaux, 2020, Cell Biochemistry and Biophysics.

Comparison of different methods for measuring the superoxide radical by EPR spectroscopy in buffer, cell lysates and cells

B. Gallez, P. Sonveaux, P. Lévêque, 2018, Free radical research.

Ketogenic diets slow melanoma growth in vivo regardless of tumor genetics and metabolic plasticity

G. Dallmann, B. Kofler, P. Sonveaux, 2022, Cancer & metabolism.

Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors

V. Grégoire, D. Labar, R. Frédérick, 2017, Oncotarget.

Mitochondrial Protein Cox7b Is a Metabolic Sensor Driving Brain-Specific Metastasis of Human Breast Cancer Cells

C. Beauloye, C. Michiels, P. Sonveaux, 2022, Cancers.

Rosiglitazone Protects Endothelial Cells From Irradiation-Induced Mitochondrial Dysfunction

W. D. De Vos, A. Aerts, Bjorn Baselet, 2020, Frontiers in Pharmacology.

Antitumor effects of in vivo caveolin gene delivery are associated with the inhibition of the proangiogenic and vasodilatory effects of nitric oxide

O. Feron, C. Bouzin, P. Martinive, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Gut microbiota-derived propionate reduces cancer cell proliferation in the liver

O. Feron, J. Verrax, Patrice D Cani, 2012, British Journal of Cancer.

Influence of Cell Detachment on the Respiration Rate of Tumor and Endothelial Cells

O. Feron, T. Copetti, B. Gallez, 2013, PloS one.

perspectives in the development of therapeutic strategies targeting cardiac or peripheral angiogenesis . Materials and Methods Cell Culture

J. Balligand, O. Feron, C. Dessy, 2001 .

EPR Investigations to Study the Impact of Mito-Metformin on the Mitochondrial Function of Prostate Cancer Cells

B. Gallez, O. Ouari, P. Sonveaux, 2022, Molecules.

Synthesis and characterization of a 5-membered ring cyclic hydroxylamine coupled to triphenylphosphonium to detect mitochondrial superoxide by EPR spectrometry

B. Gallez, P. Sonveaux, B. Driesschaert, 2019, Free radical research.

Monocarboxylate Transporter MCT1 Promotes Tumor Metastasis Independently of Its Activity as a Lactate Transporter.

C. Bouzin, P. Porporato, P. Sonveaux, 2017, Cancer research.

Direct Evidence of the Link Between Energetic Metabolism and Proliferation Capacity of Cancer Cells In Vitro.

P. Porporato, B. Gallez, P. Danhier, 2016, Advances in experimental medicine and biology.

Monocarboxylate transporters in the brain and in cancer☆

Pierre Sonveaux, Luc Pellerin, L. Pellerin, 2016, Biochimica et biophysica acta.

Lactate-Induced IL-8 Pathway in Endothelial Cells—Response

O. Feron, F. Végran, E. Seront, 2012 .

Inhibition of Mitochondrial Redox Signaling with MitoQ Prevents Metastasis of Human Pancreatic Cancer in Mice

M. Murphy, P. Porporato, F. Duhoux, 2022, Cancers.

Channels and transporters in cell metabolism.

J. Martinou, P. Sonveaux, P. Maechler, 2016, Biochimica et biophysica acta.

Reprogramming of tumor metabolism by targeting mitochondria improves tumor response to irradiation

V. Grégoire, O. Feron, G. Janssens, 2015, Acta oncologica.

Metabolic , Endocrine and Genitourinary Pathobiology Iodine Deficiency Induces a Thyroid Stimulating Hormone-Independent Early Phase of Microvascular Reshaping in the Thyroid

O. Feron, F. Soncin, I. Colin, 2010 .

Unconventional roles of lactate along the tumor and immune landscape

P. Chiarugi, L. Ippolito, P. Sonveaux, 2022, Trends in Endocrinology & Metabolism.

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer

R. Gillies, O. Feron, C. Supuran, 2017, Front. Pharmacol..

Ffar2 expression regulates leukaemic cell growth in vivo

O. Feron, Patrice D Cani, A. Neyrinck, 2017, British Journal of Cancer.

Anticancer Targets in the Glycolytic Metabolism of Tumors: A Comprehensive Review

T. Copetti, P. Porporato, P. Sonveaux, 2011, Front. Pharmacol..

Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway

Bjorn Baselet, P. Porporato, P. Sonveaux, 2015, Cellular and Molecular Life Sciences.

Synthesis and pharmacological evaluation of carboxycoumarins as a new antitumor treatment targeting lactate transport in cancer cells.

Antony E. Fernandes, O. Feron, A. Marchand, 2013, Bioorganic & medicinal chemistry.

Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction.

P. Sonveaux, F. Debiève, A. Sferruzzi-Perri, 2020, Human reproduction update.

A Fast Hydrogen Sulfide–Releasing Donor Increases the Tumor Response to Radiotherapy

V. Grégoire, B. Gallez, P. Danhier, 2015, Molecular Cancer Therapeutics.

Paclitaxel-loaded micelles enhance transvascular permeability and retention of nanomedicines in tumors.

V. Préat, A. des Rieux, F. Danhier, 2015, International journal of pharmaceutics.

Pathological effects of ionizing radiation: endothelial activation and dysfunction

A. Aerts, Bjorn Baselet, S. Baatout, 2018, Cellular and Molecular Life Sciences.

Lactate stimulates angiogenesis and accelerates the healing of superficial and ischemic wounds in mice

O. Feron, V. Préat, P. Porporato, 2012, Angiogenesis.

Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis.

Pierre Sonveaux, Carine Michiels, O. Feron, 2011, Cancer research.

Selective pro-apoptotic and antimigratory effects of polyphenol complex catechin:lysine 1:2 in breast, pancreatic and colorectal cancer cell lines.

J. Stéphenne, P. Sonveaux, F. Martel, 2019, European journal of pharmacology.

Mitochondria in cancer

P. Sonveaux, T. Capeloa, Luca X. Zampieri, 2020, Cell stress.

Mitochondria in cancer.

R. Rossignol, G. Gasparre, P. Sonveaux, 2017, Biochimica et biophysica acta. Bioenergetics.

Acute iodine deficiency induces a transient VEGF-dependent microvascular response in mammary glands involving HIF-1, ROS, and mTOR.

I. Colin, P. Sonveaux, M. Many, 2018, American journal of physiology. Cell physiology.

Assessment of melanoma extent and melanoma metastases invasion using electron paramagnetic resonance and bioluminescence imaging.

Philippe Leveque, Pierre Danhier, Bernard Gallez, 2011, Contrast media & molecular imaging.

Transport and peripheral bioactivities of nitrogen oxides carried by red blood cell hemoglobin: role in oxygen delivery.

T. McMahon, I. Lobysheva, P. Sonveaux, 2007, Physiology.

Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway

Bjorn Baselet, P. Porporato, P. Sonveaux, 2016, Cellular and Molecular Life Sciences.

A mitochondrial switch promotes tumor metastasis.

T. Copetti, C. Bouzin, P. Porporato, 2014, Cell reports.

Fitter Mitochondria Are Associated With Radioresistance in Human Head and Neck SQD9 Cancer Cells

P. Lambin, M. V. van Gisbergen, H. Smeets, 2020, Frontiers in Pharmacology.

Pro- and antitumor effects of mitochondrial reactive oxygen species

P. Porporato, P. Sonveaux, V. Payen, 2019, Cancer and Metastasis Reviews.

Cancer metabolism in space and time: Beyond the Warburg effect.

P. Porporato, L. Ippolito, P. Danhier, 2017, Biochimica et biophysica acta. Bioenergetics.

Monocarboxylate transporters in cancer

Pierre Sonveaux, P. Porporato, P. Sonveaux, 2019, Molecular metabolism.

Lactate Activates HIF-1 in Oxidative but Not in Warburg-Phenotype Human Tumor Cells

J. Verrax, T. Copetti, P. Porporato, 2012, PloS one.

Mitochondrial Transfer in Cancer: A Comprehensive Review

P. Sonveaux, Luca X. Zampieri, Justin D Rondeau, 2021, International journal of molecular sciences.

Systemic overexpression of angiopoietin-2 promotes tumor microvessel regression and inhibits angiogenesis and tumor growth.

M. Dewhirst, Yiting Cao, Chuan-Yuan Li, 2007, Cancer research.

Iodine-deficiency-induced long lasting angiogenic reaction in thyroid cancers occurs via a vascular endothelial growth factor-hypoxia inducible factor-1-dependent, but not a reactive oxygen species-dependent, pathway.

S. Baatout, I. Colin, J. Denef, 2012, Thyroid : official journal of the American Thyroid Association.

Lactate promotes glutamine uptake and metabolism in oxidative cancer cells

P. Porporato, P. Sonveaux, Christophe J. De Saedeleer, 2016, Cell cycle.

Metabolic changes associated with tumor metastasis, part 2: Mitochondria, lipid and amino acid metabolism

Bjorn Baselet, P. Porporato, P. Sonveaux, 2015, Cellular and Molecular Life Sciences.

Discovery of a novel lactate dehydrogenase tetramerization domain using epitope mapping and peptides

J. Wouters, J. Messens, E. Yildiz, 2021, The Journal of biological chemistry.

Irradiation-induced angiogenesis through the up-regulation of the nitric oxide pathway: implications for tumor radiotherapy.

Jean-Luc Balligand, Vincent Grégoire, Chantal Dessy, 2003, Cancer research.

Optimization of tumor radiotherapy with modulators of cell metabolism: toward clinical applications.

P. Porporato, B. Gallez, P. Danhier, 2013, Seminars in radiation oncology.

(+)-Catechin in a 1:2 Complex with Lysine Inhibits Cancer Cell Migration and Metastatic Take in Mice

P. Porporato, P. Danhier, P. Sonveaux, 2017, Front. Pharmacol..

Lactate Dehydrogenase B Controls Lysosome Activity and Autophagy in Cancer.

T. Copetti, C. Bouzin, Jorge Falces, 2016, Cancer cell.

Skin electroporation of a plasmid encoding hCAP-18/LL-37 host defense peptide promotes wound healing.

Robert E. W. Hancock, Gaëlle Vandermeulen, Véronique Préat, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

Prolonged inhibition and incomplete recovery of mitochondrial function in oxazolidinone-treated megakaryoblastic cell lines.

P. Tulkens, F. Van Bambeke, P. Sonveaux, 2019, International journal of antimicrobial agents.

Iodine deficiency-induced long lasting angiogenic reaction in thyroid cancers occurs via a VEGF-HIF-1, but not a ROS dependent pathway.

S. Baatout, I. Colin, J. Denef, 2012 .

Provascular strategy: targeting functional adaptations of mature blood vessels in tumors to selectively influence the tumor vascular reactivity and improve cancer treatment.

P. Sonveaux, 2008, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Long-term antigen exposure irreversibly modifies metabolic requirements for T cell function

Sabrina Bousbata, P. Porporato, P. Sonveaux, 2018, eLife.

Catabolism of Exogenous Lactate Reveals It as a Legitimate Metabolic Substrate in Breast Cancer

M. Dewhirst, S. Pizzo, J. Chi, 2013, PloS one.

Caveolin-1 Expression Is Critical for Vascular Endothelial Growth Factor–Induced Ischemic Hindlimb Collateralization and Nitric Oxide–Mediated Angiogenesis

Jean-Luc Balligand, Vincent Grégoire, Chantal Dessy, 2004, Circulation research.

Hsp90 and Caveolin Are Key Targets for the Proangiogenic Nitric Oxide–Mediated Effects of Statins

J. Balligand, C. Dessy, S. Moniotte, 2001, Circulation research.

Selected Endothelial Responses after Ionizing Radiation Exposure

A. Aerts, Bjorn Baselet, S. Baatout, 2017, Endothelial Dysfunction - Old Concepts and New Challenges.

Tumorigenesis and Neoplastic Progression Caveolin-1 Is Critical for the Maturation of Tumor Blood Vessels through the Regulation of Both Endothelial Tube Formation and Mural Cell Recruitment

C. Dessy, C. Bouzin, C. Baudelet, 2007 .

ROS and radiotherapy: more we care

P. Sonveaux, 2017, Oncotarget.

Targeting the Lactate Transporter MCT1 in Endothelial Cells Inhibits Lactate-Induced HIF-1 Activation and Tumor Angiogenesis

M. Dewhirst, F. Végran, J. Verrax, 2012, PloS one.

Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells.

A. Mai, S. Avnet, N. Baldini, 2016, American journal of cancer research.

Hsp90 Ensures the Transition from the Early Ca2+-dependent to the Late Phosphorylation-dependent Activation of the Endothelial Nitric-oxide Synthase in Vascular Endothelial Growth Factor-exposed Endothelial Cells*

J. Balligand, C. Dessy, P. Sonveaux, 2001, The Journal of Biological Chemistry.

MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases.

R. Gillies, S. Avnet, N. Baldini, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Glucose deprivation increases monocarboxylate transporter 1 (MCT1) expression and MCT1-dependent tumor cell migration

T. Copetti, P. Porporato, P. Sonveaux, 2014, Oncogene.

Functional Gene Analysis Reveals Cell Cycle Changes and Inflammation in Endothelial Cells Irradiated with a Single X-ray Dose

M. A. Benotmane, A. Aerts, R. Quintens, 2017, Front. Pharmacol..

Lactate stimulates CA IX expression in normoxic cancer cells

S. Pastoreková, P. Sonveaux, L. Brisson, 2017, Oncotarget.

Inhibition of the pentose phosphate pathway by dichloroacetate unravels a missing link between aerobic glycolysis and cancer cell proliferation

P. Porporato, B. Gallez, P. Danhier, 2015, Oncotarget.

Olaparib Is a Mitochondrial Complex I Inhibitor That Kills Temozolomide-Resistant Human Glioblastoma Cells

R. Rossignol, E. Sonveaux, F. Lefranc, 2021, International journal of molecular sciences.

Multimodal cell tracking of a spontaneous metastasis model: comparison between MRI, electron paramagnetic resonance and bioluminescence.

P. Porporato, J. Magat, B. Gallez, 2014, Contrast media & molecular imaging.

Analogues and homologues of N-palmitoylethanolamide, a putative endogenous CB(2) cannabinoid, as potential ligands for the cannabinoid receptors.

N. Delzenne, E. Hermans, P. Sonveaux, 1999, Biochimica et biophysica acta.

Involvement of nitric oxide in iodine deficiency-induced microvascular remodeling in the thyroid gland: role of nitric oxide synthase 3 and ryanodine receptors.

J. Balligand, I. Colin, P. Gilon, 2015, Endocrinology.

Differential Impact of Single-Dose Fe Ion and X-Ray Irradiation on Endothelial Cell Transcriptomic and Proteomic Responses

M. Durante, S. Tapio, C. Fournier, 2017, Front. Pharmacol..

Cancer heterogeneity is not compatible with one unique cancer cell metabolic map

J. Dumont, C. Maenhaut, M. Saiselet, 2016, Oncogene.

Pathological effects of ionizing radiation: endothelial activation and dysfunction

A. Aerts, Bjorn Baselet, S. Baatout, 2018, Cellular and Molecular Life Sciences.

Oxygen Regulation of Tumor Perfusion by S-Nitrosohemoglobin Reveals a Pressor Activity of Nitric Oxide

J. Stamler, M. Dewhirst, T. McMahon, 2005, Circulation research.

Antitumor Activity of 7-Aminocarboxycoumarin Derivatives, a New Class of Potent Inhibitors of Lactate Influx but Not Efflux

E. Seront, C. Bouzin, P. Sonveaux, 2014, Molecular Cancer Therapeutics.

Regulation of HIF-1alpha stability through S-nitrosylation.

M. Dewhirst, Chuan-Yuan Li, Ž. Vujašković, 2007, Molecular cell.

Modulation of the tumor vasculature functionality by ionizing radiation accounts for tumor radiosensitization and promotes gene delivery

V. Grégoire, J. Balligand, C. Dessy, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Glutamine activates STAT3 to control cancer cell proliferation independently of glutamine metabolism

P. Sonveaux, Martina Sboarina, Thibaut Vazeille, 2016, Oncogene.

Regulation of HIF-1α Stability through S-nitrosylation

Fang Li, Qian Huang, Mark W. Dewhirst, 2007 .

Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells.

B. Viollet, L. Bertrand, K. Sakamoto, 2014, Cardiovascular research.

An EPR Study Using Cyclic Hydroxylamines To Assess The Level of Mitochondrial ROS in Superinvasive Cancer Cells

P. Porporato, B. Gallez, P. Sonveaux, 2020, Cell Biochemistry and Biophysics.

Multimodality Imaging Identifies Distinct Metabolic Profiles In Vitro and In Vivo1

Anne Bol, Vincent Grégoire, Bernard Gallez, 2016, Neoplasia.

In Vitro and In Vivo Characterization of MCT1 Inhibitor AZD3965 Confirms Preclinical Safety Compatible with Breast Cancer Treatment

P. Sonveaux, O. Schakman, Marine C. N. M. Blackman, 2021, Cancers.

Mitochondria Participate in Chemoresistance to Cisplatin in Human Ovarian Cancer Cells

R. Rossignol, C. Bouzin, P. Sonveaux, 2020, Molecular Cancer Research.

Specific HIF-2α (Hypoxia-Inducible Factor-2) Inhibitor PT2385 Mitigates Placental Dysfunction In Vitro and in a Rat Model of Preeclampsia (RUPP)

L. Gatto, P. Baldin, A. Loriot, 2023, Hypertension.

Clinical and in Vitro Evidence against Placenta Infection at Term by Severe Acute Respiratory Syndrome Coronavirus 2

P. Baldin, O. Danhaive, P. Sonveaux, 2021, The American Journal of Pathology.

Reversal of temporal and spatial heterogeneities in tumor perfusion identifies the tumor vascular tone as a tunable variable to improve drug delivery

V. Grégoire, C. Bouzin, C. Baudelet, 2006, Molecular Cancer Therapeutics.

Endothelin-1 is a critical mediator of myogenic tone in tumor arterioles: implications for cancer treatment.

V. Grégoire, J. Balligand, C. Dessy, 2004, Cancer research.

Targeting Tumor Perfusion and Oxygenation to Improve the Outcome of Anticancer Therapy

Pierre Sonveaux, P. Sonveaux, B. Jordan, 2012, Front. Pharmacol..

Targeting tumor perfusion and oxygenation modulates hypoxia and cancer sensitivity to radiotherapy and systemic therapies

P. Sonveaux, B. Jordan, 2012 .

Nitric oxide delivery to cancer: why and how?

B. Gallez, P. Sonveaux, B. Jordan, 2009, European journal of cancer.

Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors.

C. Dessy, F. Végran, R. Boidot, 2012, Cancer research.

Statins Alleviate Tumor Hypoxia in Prostate Cancer Models by Decreasing Oxygen Consumption: An Opportunity for Radiosensitization?

B. Gallez, P. Sonveaux, B. Jordan, 2022, Biomolecules.

The Acidic Tumor Microenvironment Promotes the Reconversion of Nitrite into Nitric Oxide: Towards a New and Safe Radiosensitizing Strategy

A. Noël, C. Dessy, B. Gallez, 2008, Clinical Cancer Research.

Discovery of small molecules interacting at lactate dehydrogenases tetrameric interface using a biophysical screening cascade.

J. Wouters, R. Frédérick, P. Sonveaux, 2022, European journal of medicinal chemistry.

Small Molecule Therapeutics AntitumorActivity of 7-AminocarboxycoumarinDerivatives , a NewClass of Potent Inhibitors of Lactate In fl ux but Not Ef fl ux

E. Seront, C. Bouzin, P. Sonveaux, 2014 .

Lactate stimulates angiogenesis and accelerates the healing of superficial and ischemic wounds in mice

V. Préat, P. Porporato, J. Thissen, 2012, Angiogenesis.

Lactate does not activate NF-κB in oxidative tumor cells

T. Copetti, P. Sonveaux, J. Pérez-Escuredo, 2015, Front. Pharmacol..

Pro- and antitumor effects of mitochondrial reactive oxygen species

P. Porporato, P. Sonveaux, V. Payen, 2019, Cancer and Metastasis Reviews.

Metabolic changes associated with tumor metastasis, part 2: Mitochondria, lipid and amino acid metabolism

Bjorn Baselet, P. Porporato, P. Sonveaux, 2016, Cellular and Molecular Life Sciences.

Activated macrophages as a novel determinant of tumor cell radioresponse: the role of nitric oxide-mediated inhibition of cellular respiration and oxygen sparing.

D. Verellen, G. Storme, M. de Ridder, 2010, International journal of radiation oncology, biology, physics.

Targeting Endothelial Cell Metabolism by Inhibition of Pyruvate Dehydrogenase Kinase and Glutaminase-1

B. Gallez, P. Sonveaux, N. Joudiou, 2020, Journal of clinical medicine.

Involvement of mTOR and Regulation by AMPK in Early Iodine Deficiency-Induced Thyroid Microvascular Activation.

L. Bertrand, S. Horman, I. Colin, 2016, Endocrinology.

Metabolism and microenvironment in cancer plasticity

C. Supuran, A. Otto, S. Avnet, 2016, Cancer & Metabolism.

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Adaptations and Targets in Cancer

S. Pastoreková, S. Avnet, N. Baldini, 2019, Front. Oncol..

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Cancer Metabolism

S. Pastoreková, A. Otto, S. Avnet, 2018, Front. Oncol..

In vivo visualization and ex vivo quantification of murine breast cancer cells in the mouse brain using MRI cell tracking and electron paramagnetic resonance

V. Haufroid, C. Bouzin, P. Porporato, 2015, NMR in biomedicine.

Non‐invasive in vivo imaging of early metabolic tumor response to therapies targeting choline metabolism

V. Grégoire, P. Porporato, J. Magat, 2016, International journal of cancer.

Paracrine nitric oxide induces expression of cardiac sarcomeric proteins in adult progenitor cells through soluble guanylyl cyclase/cyclic-guanosine monophosphate and Wnt/β-catenin inhibition.

J. Balligand, S. Janssens, P. Gilon, 2016, Cardiovascular research.

Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis.

F. Végran, R. Boidot, C. Michiels, 2011, Cancer research.