Hiroki Sekine

发表

Roles of CNC Transcription Factors NRF1 and NRF2 in Cancer

H. Motohashi, Hiroki Sekine, 2021, Cancers.

Renal Anemia Model Mouse Established by Transgenic Rescue with an Erythropoietin Gene Lacking Kidney-Specific Regulatory Elements

Masayuki Yamamoto, I. Hirano, R. Shimizu, 2016, Molecular and Cellular Biology.

Unique and Overlapping Transcriptional Roles of Arylhydrocarbon Receptor Nuclear Translocator (Arnt) and Arnt2 in Xenobiotic and Hypoxic Responses*

Y. Fujii‐Kuriyama, Masayuki Yamamoto, J. Mimura, 2006, Journal of Biological Chemistry.

Hypoxia Signaling Cascade for Erythropoietin Production in Hepatocytes

K. Takeda, Masayuki Yamamoto, T. Miyata, 2015, Molecular and Cellular Biology.

An immortalized cell line derived from renal erythropoietin-producing (REP) cells demonstrates their potential to transform into myofibroblasts

S. Ito, Masayuki Yamamoto, I. Hirano, 2019, Scientific Reports.

Tumors sweeten macrophages with acids

Masayuki Yamamoto, H. Motohashi, Hiroki Sekine, 2018, Nature Immunology.

HIF-1α-prolyl hydroxylase: molecular target of nitric oxide in the hypoxic signal transduction pathway

Y. Fujii‐Kuriyama, T. Shuin, K. Sogawa, 2002 .

Hypoxia-inducible factor-1α and poly [ADP ribose] polymerase 1 cooperatively regulate Notch3 expression under hypoxia via a noncanonical mechanism

H. Kato, L. Poellinger, H. Masai, 2022, The Journal of biological chemistry.

SUMO Modification Regulates the Transcriptional Repressor Function of Aryl Hydrocarbon Receptor Repressor*

Y. Fujii‐Kuriyama, H. Okawa, J. Mimura, 2009, Journal of Biological Chemistry.

Glucocorticoid receptor signaling represses the antioxidant response by inhibiting histone acetylation mediated by the transcriptional activator NRF2

Hiroki Shima, K. Igarashi, H. Motohashi, 2017, The Journal of Biological Chemistry.

Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes

S. Ito, A. Fukamizu, Masayuki Yamamoto, 2017, Science Signaling.

PNPO-PLP Axis Senses Prolonged Hypoxia by Regulating Lysosomal Activity

K. Kinoshita, F. Katsuoka, F. Miura, 2022, bioRxiv.

The Mediator Subunit MED16 Transduces NRF2-Activating Signals into Antioxidant Gene Expression

Y. Katoh, Masayuki Yamamoto, Hiroki Shima, 2015, Molecular and Cellular Biology.

The Mediator Subunit MED 16 Transduces NRF 2-activating Signals into 1 Antioxidant Gene Expression 2 3

Y. Katoh, Hiroki Shima, K. Igarashi, 2015 .

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

K. Nakayama, N. Tanaka, Takafumi Suzuki, 2016, Nature Communications.

Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers

K. Kinoshita, A. Sakurada, Masayuki Yamamoto, 2020, Nature Communications.

Erythropoietin Synthesis in Renal Myofibroblasts Is Restored by Activation of Hypoxia Signaling.

S. Ito, K. Takeda, A. Nishiyama, 2016, Journal of the American Society of Nephrology : JASN.

O-GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1

Masayuki Yamamoto, Hiroki Shima, K. Igarashi, 2018, Molecular and Cellular Biology.

Hypersensitivity of Aryl Hydrocarbon Receptor-Deficient Mice to Lipopolysaccharide-Induced Septic Shock

Y. Fujii‐Kuriyama, K. Igarashi, J. Kanno, 2009, Molecular and Cellular Biology.

Contribution of NRF2 to sulfur metabolism and mitochondrial activity

T. Akaike, H. Motohashi, Hiroki Sekine, 2023, Redox biology.

Tumors sweeten macrophages with acids

Masayuki Yamamoto, H. Motohashi, Hiroki Sekine, 2018, Nature Immunology.

CEBPB is Required for NRF2-Mediated Drug Resistance in NRF2-Activated Non-Small Cell Lung Cancer Cells.

K. Kinoshita, F. Katsuoka, H. Motohashi, 2022, Journal of biochemistry.

Hypersensitivity of Aryl Hydrocarbon Receptor-Deficient Mice to Lipopolysaccharide-Induced Septic Shock

Y. Fujii‐Kuriyama, K. Igarashi, J. Kanno, 2009, Molecular and Cellular Biology.

HIF-1alpha-prolyl hydroxylase: molecular target of nitric oxide in the hypoxic signal transduction pathway.

Y. Fujii‐Kuriyama, T. Shuin, K. Sogawa, 2002, Biochemical and biophysical research communications.

Sulfur metabolic response in macrophage limits excessive inflammatory response by creating a negative feedback loop

T. Akaike, Hideyo Sato, H. Motohashi, 2023, Redox biology.

The anti-inflammatory and anti-oxidative effect of a classical hypnotic bromovalerylurea mediated by the activation of NRF2

H. Motohashi, Y. Nakajima, H. Takeda, 2023, Journal of biochemistry.

Unique and overlapping roles of NRF2 and NRF1 in transcriptional regulation

H. Motohashi, Hiroki Sekine, 2023, Journal of clinical biochemistry and nutrition.

Lactate dehydrogenase C is required for the protein expression of a sperm-specific isoform of lactate dehydrogenase A

D. Saigusa, Hiroki Shima, T. Arima, 2018, Journal of biochemistry.