Yong Zhang

发表

Metastatic Recurrence in a Pancreatic Cancer Patient Derived Orthotopic Xenograft (PDOX) Nude Mouse Model Is Inhibited by Neoadjuvant Chemotherapy in Combination with Fluorescence-Guided Surgery with an Anti-CA 19-9-Conjugated Fluorophore

I. Endo, M. Bouvet, R. Hoffman, 2014, PloS one.

Fluorescence-guided surgery, but not bright-light surgery, prevents local recurrence in a pancreatic cancer patient derived orthotopic xenograft (PDOX) model resistant to neoadjuvant chemotherapy (NAC).

I. Endo, M. Bouvet, R. Hoffman, 2015, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].

Protein-tyrosine Pseudokinase 7 (PTK7) Directs Cancer Cell Motility and Metastasis*

A. Strongin, R. Hoffman, N. Prigozhina, 2014, The Journal of Biological Chemistry.

Tumor-targeting Salmonella typhimurium A1-R regresses an osteosarcoma in a patient-derived xenograft model resistant to a molecular-targeting drug

I. Endo, S. Dry, R. Hoffman, 2016, Oncotarget.

Cancer-cell killing by engineered Salmonella imaged by multiphoton tomography in live mice.

K. König, R. Hoffman, A. Uchugonova, 2012, Anticancer research.

Tumor‐Targeting Salmonella typhimurium A1‐R Promotes Tumoricidal CD8+ T Cell Tumor Infiltration and Arrests Growth and Metastasis in a Syngeneic Pancreatic‐Cancer Orthotopic Mouse Model

I. Endo, M. Bouvet, R. Hoffman, 2018, Journal of cellular biochemistry.

Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models

M. Bouvet, R. Hoffman, J. Y. Lee, 2016, Oncotarget.

Photoimmunotherapy lowers recurrence after pancreatic cancer surgery in orthotopic nude mouse models.

Hisataka Kobayashi, M. Bouvet, R. Hoffman, 2015, The Journal of surgical research.

Efficacy of Salmonella typhimurium A1‐R Versus Chemotherapy on a Pancreatic Cancer Patient‐Derived Orthotopic Xenograft (PDOX)

I. Endo, M. Bouvet, R. Hoffman, 2014, Journal of cellular biochemistry.

Efficacy comparison of traditional Chinese medicine LQ versus gemcitabine in a mouse model of pancreatic cancer

Fang Liu, M. Bouvet, R. Hoffman, 2013, Journal of cellular biochemistry.

Comparison of efficacy of Salmonella typhimurium A1-R and chemotherapy on stem-like and non-stem human pancreatic cancer cells

I. Endo, M. Bouvet, R. Hoffman, 2013, Cell cycle.

Therapeutic efficacy of tumor-targeting Salmonella typhimurium A1-R on human colorectal cancer liver metastasis in orthotopic nude-mouse models

I. Endo, M. Bouvet, R. Hoffman, 2015, Oncotarget.

Comparison of the selective targeting efficacy of Salmonella typhimurium A1-R and VNP20009 on the Lewis lung carcinoma in nude mice

R. Hoffman, N. Zhang, Ming Zhao, 2015, Oncotarget.

Adjuvant treatment with tumor-targeting Salmonella typhimurium A1-R reduces recurrence and increases survival after liver metastasis resection in an orthotopic nude mouse model

I. Endo, M. Bouvet, R. Hoffman, 2015, Oncotarget.

Tumor-targeting Salmonella typhimurium A1-R arrests growth of breast-cancer brain metastasis

R. Hoffman, N. Zhang, Ming Zhao, 2014, Oncotarget.

Determination of the optimal route of administration of Salmonella typhimurium A1-R to target breast cancer in nude mice.

R. Hoffman, N. Zhang, Ming Zhao, 2012, Anticancer research.

Efficacy against lung metastasis with a tumor-targeting mutant of Salmonella typhimurium in immunocompetent mice

Fang Liu, R. Hoffman, Ming Zhao, 2012, Cell cycle.

Tumor-targeting Salmonella typhimurium A1-R prevents experimental human breast cancer bone metastasis in nude mice

N. Yamamoto, H. Tsuchiya, M. Bouvet, 2014, Oncotarget.

Salmonella typhimurium A1-R targeting of a chemotherapy-resistant BRAF-V600E melanoma in a patient-derived orthotopic xenograft (PDOX) model is enhanced in combination with either vemurafenib or temozolomide

S. Dry, M. Unno, R. Hoffman, 2017, Cell cycle.

Tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin eradicate soft tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) model

I. Endo, M. Bouvet, R. Hoffman, 2016, Oncotarget.

Imaging the Different Mechanisms of Prostate Cancer Cell-killing by Tumor-targeting Salmonella typhimurium A1-R.

R. Hoffman, A. Uchugonova, K. Koenig, 2015, Anticancer research.

Tumor-targeting Salmonella typhimurium A1-R decoys quiescent cancer cells to cycle as visualized by FUCCI imaging and become sensitive to chemotherapy

M. Bouvet, R. Hoffman, T. Fujiwara, 2014, Cell cycle.

Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy

I. Endo, M. Bouvet, R. Hoffman, 2016, Oncotarget.

Complementarity of variable-magnification and spectral-separation fluorescence imaging systems for noninvasive detection of metastasis and intravital detection of single cancer cells in mouse models.

R. Hoffman, N. Zhang, Ming Zhao, 2015, Anticancer research.

Establishment of a Patient-Derived Orthotopic Xenograft (PDOX) Model of HER-2-Positive Cervical Cancer Expressing the Clinical Metastatic Pattern

I. Endo, M. Bouvet, R. Hoffman, 2015, PloS one.

Patient-derived orthotopic xenograft (PDOX) nude mouse model of soft-tissue sarcoma more closely mimics the patient behavior in contrast to the subcutaneous ectopic model.

I. Endo, M. Bouvet, R. Hoffman, 2015, Anticancer research.

Morphological and gene-expression characterization of viable heterogeneous circulating tumor cells size-captured and cultured from triple-negative breast cancer mouse models

R. Hoffman, V. Bobek, K. Kološtová, 2016 .

Salmonella typhimurium A1-R tumor targeting in immunocompetent mice is enhanced by a traditional Chinese medicine herbal mixture.

R. Hoffman, N. Zhang, S. Su, 2013, Anticancer research.

Comparison of Efficacy and Toxicity of Traditional Chinese Medicine (TCM) Herbal Mixture LQ and Conventional Chemotherapy on Lung Cancer Metastasis and Survival in Mouse Models

Fang Liu, Ming Zhao, Lei Zhang, 2014, PloS one.

Real-time imaging of apoptosis induction of human breast cancer cells by the traditional Chinese medicinal herb tubeimu.

Meng Yang, R. Hoffman, S. Yano, 2012, Anticancer research.

Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models

I. Endo, M. Bouvet, R. Hoffman, 2014, Oncotarget.

Tumor-Targeting Salmonella typhimurium A1-R Arrests a Chemo-Resistant Patient Soft-Tissue Sarcoma in Nude Mice

I. Endo, M. Bouvet, R. Hoffman, 2015, PloS one.

Tumor-Targeting Salmonella typhimurium A1-R in Combination with Trastuzumab Eradicates HER-2-Positive Cervical Cancer Cells in Patient-Derived Mouse Models

I. Endo, M. Bouvet, R. Hoffman, 2015, PloS one.

Inhibition of spontaneous and experimental lung metastasis of soft-tissue sarcoma by tumor-targeting Salmonella typhimurium A1-R

N. Yamamoto, H. Tsuchiya, M. Bouvet, 2014, Oncotarget.

Precise surgery of in the lung in mouse models enabled by in situ fluorescence labelling with a adenovirus.

M. Bouvet, R. Hoffman, T. Fujiwara, 2015 .

Real‐Time GFP Intravital Imaging of the Differences in Cellular and Angiogenic Behavior of Subcutaneous and Orthotopic Nude‐Mouse Models of Human PC‐3 Prostate Cancer

N. Seki, M. Bouvet, R. Hoffman, 2016, Journal of cellular biochemistry.

Toxicology and efficacy of tumor-targeting Salmonella typhimurium A1-R compared to VNP 20009 in a syngeneic mouse tumor model in immunocompetent mice.

S. Dry, Xiaoen Wang, R. Hoffman, 2017, Oncotarget.

High efficacy of tumor-targeting Salmonella typhimurium A1-R on a doxorubicin- and dactolisib-resistant follicular dendritic-cell sarcoma in a patient-derived orthotopic xenograft PDOX nude mouse model

S. Dry, M. Bouvet, R. Hoffman, 2016, Oncotarget.

Fluorescence‐guided surgery of human prostate cancer experimental bone metastasis in nude mice using anti‐CEA DyLight 650 for tumor illumination

H. Tsuchiya, M. Bouvet, R. Hoffman, 2016, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Tumor-targeting Salmonella typhimurium A1-R inhibits human prostate cancer experimental bone metastasis in mouse models

M. Bouvet, R. Hoffman, H. Nakanishi, 2015, Oncotarget.

High-efficacy targeting of colon-cancer liver metastasis with Salmonella typhimurium A1-R via intra-portal-vein injection in orthotopic nude-mouse models

M. Unno, M. Bouvet, R. Hoffman, 2016, Oncotarget.

In Vitro Culture and Characterization of Human Lung Cancer Circulating Tumor Cells Isolated by Size Exclusion from an Orthotopic Nude-Mouse Model Expressing Fluorescent Protein

R. Hoffman, V. Bobek, K. Kološtová, 2014, Journal of Fluorescence.

Intraperitoneal administration of tumor-targeting Salmonella typhimurium A1-R inhibits disseminated human ovarian cancer and extends survival in nude mice

H. Tsuchiya, M. Bouvet, R. Hoffman, 2015, OncoTarget.

Efficacy of Tumor‐Targeting Salmonella Typhimurium A1‐R on Nude Mouse Models of Metastatic and Disseminated Human Ovarian Cancer

M. Bouvet, R. Hoffman, H. Matsubara, 2014, Journal of cellular biochemistry.

A patient-derived orthotopic xenograft (PDOX) mouse model of a cisplatinum-resistant osteosarcoma lung metastasis that was sensitive to temozolomide and trabectedin: implications for precision oncology

S. Dry, H. Tsuchiya, R. Hoffman, 2017, Oncotarget.

The irony of highly-effective bacterial therapy of a patient-derived orthotopic xenograft (PDOX) model of Ewing's sarcoma, which was blocked by Ewing himself 80 years ago

Thinzar M. Lwin, I. Endo, S. Dry, 2017, Cell cycle.

Tumor‐Targeting Salmonella typhimurium A1‐R Sensitizes Melanoma With a BRAF‐V600E Mutation to Vemurafenib in a Patient‐Derived Orthotopic Xenograft (PDOX) Nude Mouse Model

S. Dry, M. Unno, R. Hoffman, 2017, Journal of cellular biochemistry.

Tumor-targeting Salmonella typhimurium A1-R combined with temozolomide regresses malignant melanoma with a BRAF-V600E mutation in a patient-derived orthotopic xenograft (PDOX) model

S. Dry, M. Unno, R. Hoffman, 2016, Oncotarget.

Efficacy of Tumor-Targeting Salmonella A1-R on a Melanoma Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Model

M. Bouvet, R. Hoffman, Ming Zhao, 2016, PloS one.

Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model

I. Endo, S. Dry, M. Bouvet, 2016, Oncotarget.

Successful fluorescence-guided surgery on human colon cancer patient-derived orthotopic xenograft mouse models using a fluorophore-conjugated anti-CEA antibody and a portable imaging system.

Yukihiko Hiroshima, Robert M Hoffman, Michael Bouvet, 2014, Journal of laparoendoscopic & advanced surgical techniques. Part A.

VEGF-C ShRNA inhibits pancreatic cancer growth and lymphangiogenesis in an orthotopic fluorescent nude mouse model.

R. Hoffman, Yu Sun, Zhijian Yang, 2013, Anticancer research.

Spatial–temporal FUCCI imaging of each cell in a tumor demonstrates locational dependence of cell cycle dynamics and chemoresponsiveness

M. Bouvet, R. Hoffman, T. Fujiwara, 2014, Cell cycle.

Solid tumors provide niche-specific conditions that lead to preferential growth of Salmonella

S. Porwollik, R. Hoffman, P. Desai, 2016 .

Fluorescence-guided surgery of prostate cancer bone metastasis.

N. Sugimoto, N. Yamamoto, H. Tsuchiya, 2014, The Journal of surgical research.

Orthotopic Implantation of Intact Tumor Tissue Leads to Metastasis of OCUM-2MD3 Human Gastric Cancer in Nude Mice Visualized in Real Time by Intravital Fluorescence Imaging.

I. Endo, Xiaoen Wang, M. Bouvet, 2016, Anticancer research.

Ovarian Tumor Attachment, Invasion, and Vascularization Reflect Unique Microenvironments in the Peritoneum: Insights from Xenograft and Mathematical Models

Abbas Shirinifard, Bridget S. Wilson, Kimberly R. Kanigel Winner, 2013, Front. Oncol..

Fluorescence-Guided Surgery in Combination with UVC Irradiation Cures Metastatic Human Pancreatic Cancer in Orthotopic Mouse Models

I. Endo, M. Bouvet, R. Hoffman, 2014, PLoS ONE.

Fluorescent-Antibody Targeting of Insulin-Like Growth Factor-1 Receptor Visualizes Metastatic Human Colon Cancer in Orthotopic Mouse Models

M. Bouvet, R. Hoffman, T. Murakami, 2016, PloS one.

Real-time Non-invasive Spectral Imaging of Orthotopic Red Fluorescent Protein-expressing Lung Tumor Growth in Nude Mice.

R. Hoffman, N. Zhang, Ming Zhao, 2015, Anticancer research.

Photoimmunotherapy Inhibits Tumor Recurrence After Surgical Resection on a Pancreatic Cancer Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model

Yukihiko Hiroshima, Michael Bouvet, Hisataka Kobayashi, 2015, Annals of Surgical Oncology.

Near Infra-Red Photoimmunotherapy with Anti-CEA-IR700 Results in Extensive Tumor Lysis and a Significant Decrease in Tumor Burden in Orthotopic Mouse Models of Pancreatic Cancer

Yukihiko Hiroshima, Michael Bouvet, Hisataka Kobayashi, 2015, PloS one.

Cervical Cancer Patient-Derived Orthotopic Xenograft (PDOX) Is Sensitive to Cisplatinum and Resistant to Nab-paclitaxel.

Thinzar M. Lwin, I. Endo, M. Bouvet, 2017, Anticancer research.

Surgically-Induced Multi-organ Metastasis in an Orthotopic Syngeneic Imageable Model of 4T1 Murine Breast Cancer.

R. Hoffman, N. Zhang, Ming Zhao, 2015, Anticancer research.

Tumor-targeting Salmonella typhimurium A1-R Inhibits Osteosarcoma Angiogenesis in the In Vivo Gelfoam® Assay Visualized by Color-coded Imaging.

R. Hoffman, Ming Zhao, F. Kanaya, 2018, Anticancer research.

Fluorescence‐guided surgery improves outcome in an orthotopic osteosarcoma nude‐mouse model

H. Tsuchiya, M. Bouvet, R. Hoffman, 2014, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Multiphoton tomography visualizes collagen fibers in the tumor microenvironment that maintain cancer‐cell anchorage and shape

K. König, M. Bouvet, R. Hoffman, 2013, Journal of cellular biochemistry.

In Vitro Culture and Characterization of Human Lung Cancer Circulating Tumor Cells Isolated by Size Exclusion from an Orthotopic Nude-Mouse Model Expressing Fluorescent Protein

R. Hoffman, V. Bobek, K. Kološtová, 2014, Journal of Fluorescence.

Fluorescence-Guided Surgery of Liver Metastasis in Orthotopic Nude-Mouse Models

I. Endo, M. Bouvet, R. Hoffman, 2015, PloS one.

Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer.

Chin Wee Tan, Dharmesh D. Bhuva, Eric C Greenwald, 2023, Cell chemical biology.

Precise navigation surgery of tumours in the lung in mouse models enabled by in situ fluorescence labelling with a killer-reporter adenovirus

M. Bouvet, R. Hoffman, T. Fujiwara, 2015, BMJ Open Respiratory Research.

Intraoperative imaging of metastatic lymph nodes using a fluorophore-conjugated antibody in a HER2/neu-expressing orthotopic breast cancer mouse model.

Jin-hai Tang, R. Hoffman, Yu Sun, 2013, Anticancer research.

Spatial–temporal FUCCI imaging of each cell in a tumor demonstrates locational dependence of cell cycle dynamics and chemoresponsiveness

M. Bouvet, R. Hoffman, T. Fujiwara, 2014, Cell cycle.

Polyethylene Glycol (PEG) Linked to Near Infrared (NIR) Dyes Conjugated to Chimeric Anti-Carcinoembryonic Antigen (CEA) Antibody Enhances Imaging of Liver Metastases in a Nude-Mouse Model of Human Colon Cancer

Yukihiko Hiroshima, Michael Bouvet, Robert M. Hoffman, 2014, PloS one.