S. Malik

发表

Differential Targeting of Gßγ-Subunit Signaling with Small Molecules

Alan V. Smrcka, Dianqing Wu, J. Bidlack, 2006, Science.

Differential targeting of Gbetagamma-subunit signaling with small molecules.

Dianqing Wu, J. Bidlack, Dianqing Wu, 2006, Science.

Phospholipase Cε Hydrolyzes Perinuclear Phosphatidylinositol 4-Phosphate to Regulate Cardiac Hypertrophy

B. Blaxall, A. Smrcka, D. Yule, 2013, Cell.

Transverse tubule remodeling enhances Orai1-dependent Ca2+ entry in skeletal muscle

T. Takano, A. Michelucci, S. Boncompagni, 2019, eLife.

Compartmentalized cyclic nucleotides have opposing effects on regulation of hypertrophic phospholipase Cε signaling in cardiac myocytes.

Xiaodong Cheng, C. Nash, A. Smrcka, 2018, Journal of molecular and cellular cardiology.

Differential role of MEK5alpha and MEK5beta in BMK1/ERK5 activation.

J. Abe, W. Che, J. Yang, 2004, The Journal of biological chemistry.

Differential Role of MEK5α and MEK5β in BMK1/ERK5 Activation*

J. Abe, W. Che, J. Yang, 2003, Journal of Biological Chemistry.

Dual Topology of the Melanocortin-2 Receptor Accessory Protein Is Stable

S. Malik, P. M. Hinkle, Z. Maben, 2016, Front. Endocrinol..

Postdevelopmental knockout of Orai1 improves muscle pathology in a mouse model of Duchenne muscular dystrophy

A. Michelucci, M. García-Castañeda, R. Dirksen, 2022, The Journal of general physiology.

Missense mutations in inositol 1,4,5-trisphosphate receptor type 3 result in leaky Ca2+ channels and activation of store-operated Ca2+ entry

A. Liston, D. Yule, S. Malik, 2022, iScience.

Regulation of Epidermal Growth Factor-induced Connexin 43 Gap Junction Communication by Big Mitogen-activated Protein Kinase 1/ERK5 but Not ERK1/2 Kinase Activation*

Chen Yan, J. Abe, Jiing-Dwan Lee, 2003, The Journal of Biological Chemistry.

Interleukin-1beta inhibits gamma-aminobutyric acid type A (GABA(A)) receptor current in cultured hippocampal neurons.

S. Malik, S. Wang, J. Yang, 2000, The Journal of pharmacology and experimental therapeutics.

Regulatory Interactions between the Amino Terminus of G-protein βγ Subunits and the Catalytic Domain of Phospholipase Cβ2*

M. Ghosh, A. Smrcka, Tabetha M. Bonacci, 2005, Journal of Biological Chemistry.

Epac2‐dependent mobilization of intracellular Ca2+ by glucagon‐like peptide‐1 receptor agonist exendin‐4 is disrupted in β‐cells of phospholipase C‐ɛ knockout mice

O. Chepurny, G. Holz, C. Leech, 2010, The Journal of physiology.

Mouse model of severe recessive RYR1-related myopathy.

J. Dowling, A. Michelucci, M. García-Castañeda, 2019, Human molecular genetics.

Phospholipase Cϵ Scaffolds to Muscle-specific A Kinase Anchoring Protein (mAKAPβ) and Integrates Multiple Hypertrophic Stimuli in Cardiac Myocytes*

A. Smrcka, S. Malik, M. Kapiloff, 2011, The Journal of Biological Chemistry.

Stimulation of Cellular Signaling and G Protein Subunit Dissociation by G Protein βγ Subunit-binding Peptides*

R. Neubig, K. Griendling, M. Ghosh, 2003, Journal of Biological Chemistry.

Stimulation of cellular signaling and G protein subunit dissociation by G protein betagamma subunit-binding peptides.

R. Neubig, K. Griendling, M. Ghosh, 2003, The Journal of biological chemistry.

G protein βγ subunits regulate cardiomyocyte hypertrophy through a perinuclear Golgi phosphatidylinositol 4-phosphate hydrolysis pathway

R. Irannejad, P. Wedegaertner, A. Smrcka, 2015, Molecular biology of the cell.

Disease-associated mutations in inositol 1,4,5-trisphosphate receptor subunits impair channel function

D. Yule, S. Malik, K. Alzayady, 2020, The Journal of Biological Chemistry.

Adenylyl Cyclase 5 Regulation by Gβγ Involves Isoform-Specific Use of Multiple Interaction Sites

C. Dessauer, Rachna Sadana, A. Smrcka, 2015, Molecular Pharmacology.

Induction of Ca++ influx and intracellular Ca++ release in isolated rat aorta and mesenteric resistance vessels by norepinephrine activation of alpha-1 receptors.

S. Malik, C. Cauvin, 1984, The Journal of pharmacology and experimental therapeutics.

Potassium conservation is impaired in mice with reduced renal expression of Kir4.1.

Junhui Zhang, G. Porter, Tong Wang, 2018, American journal of physiology. Renal physiology.

Epac and Phospholipase Cϵ Regulate Ca2+ Release in the Heart by Activation of Protein Kinase Cϵ and Calcium-Calmodulin Kinase II*

B. Blaxall, R. Dirksen, A. Smrcka, 2009, Journal of Biological Chemistry.

Phospholipase Cε is a nexus for Rho and Rap-mediated G protein-coupled receptor-induced astrocyte proliferation

J. Brown, A. Smrcka, S. Malik, 2007, Proceedings of the National Academy of Sciences.

Epac-mediated Activation of Phospholipase Cϵ Plays a Critical Role in β-Adrenergic Receptor-dependent Enhancement of Ca2+ Mobilization in Cardiac Myocytes*

Huan Wang, K. Kaproth-Joslin, B. Blaxall, 2007, Journal of Biological Chemistry.

Phosphatidylinositol 4-phosphate is a major source of GPCR-stimulated phosphoinositide production

A. Anantharam, A. Smrcka, D. Yule, 2018, Science Signaling.

Knock down of spinal NMDA receptors reduces NMDA and formalin evoked behaviors in rat

M. Garry, J. Yang, S. Malik, 2000, Neuroreport.

Epac-mediated activation of phospholipase C(epsilon) plays a critical role in beta-adrenergic receptor-dependent enhancement of Ca2+ mobilization in cardiac myocytes.

Huan Wang, K. Kaproth-Joslin, B. Blaxall, 2007, The Journal of biological chemistry.

Adrenocorticotropic Hormone (ACTH) Responses Require Actions of the Melanocortin-2 Receptor Accessory Protein on the Extracellular Surface of the Plasma Membrane*

S. Malik, P. M. Hinkle, Z. Maben, 2015, The Journal of Biological Chemistry.

Dynamic regulation of neutrophil polarity and migration by the heterotrimeric G protein subunits Gαi-GTP and Gβγ

Chinmay R. Surve, Minsoo Kim, A. Smrcka, 2016, Science Signaling.

Interleukin-1 b Inhibits g-Aminobutyric Acid Type A ( GABAA ) Receptor Current in Cultured Hippocampal Neurons

J. Yang, S. Malik, Sam Wang, 2000 .

Ric-8 Enhances G Protein βγ-Dependent Signaling in Response to βγ-Binding Peptides in Intact Cells

M. Ghosh, G. Tall, A. Smrcka, 2005, Molecular Pharmacology.

Ric-8 enhances G protein betagamma-dependent signaling in response to betagamma-binding peptides in intact cells.

M. Ghosh, G. Tall, A. Smrcka, 2005, Molecular pharmacology.

M3 Muscarinic Receptor Interaction with Phospholipase C β3 Determines Its Signaling Efficiency*

M. Adjobo-Hermans, G. Tall, A. Smrcka, 2014, The Journal of Biological Chemistry.

Regulation of Store-Operated Ca2+ Entry by IP3 Receptors Independent of Their Ability to Release Ca2+

Colin W. Taylor, G. Hasan, D. Yule, 2021, bioRxiv.

Regulation of store-operated Ca2+ entry by IP3 receptors independent of their ability to release Ca2+

G. Hasan, D. Yule, S. Malik, 2023, bioRxiv.

CREB regulates the expression of Type 1 Inositol 1,4,5-trisphosphate receptors.

D. Yule, S. Malik, L. Wagner, 2021, Journal of cell science.

Epac2‐dependent mobilization of intracellular Ca2+ by glucagon‐like peptide‐1 receptor agonist exendin‐4 is disrupted in β‐cells of phospholipase C‐ɛ knockout mice

O. Chepurny, G. Holz, C. Leech, 2010, Journal of Physiology.

Phospholipase Cϵ Scaffolds to Muscle-specific A Kinase Anchoring Protein (mAKAPβ) and Integrates Multiple Hypertrophic Stimuli in Cardiac Myocytes*

A. Smrcka, S. Malik, M. Kapiloff, 2011, The Journal of Biological Chemistry.