M. van den Broeck

发表

Estimation of the genetic contribution of presenilin-1 and -2 mutations in a population-based study of presenile Alzheimer disease.

A Hofman, A. Hofman, J. Hardy, 1998, Human molecular genetics.

PRNP Val129 homozygosity increases risk for early‐onset Alzheimer's disease

A. Hofman, C. V. van Duijn, M. Cruts, 2003, Annals of neurology.

TheTNFRSF6 gene is not implicated in familial early-onset Alzheimer's disease

L. Feuk, A. Brookes, C. V. van Duijn, 2001, Human Genetics.

Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family.

K. Sleegers, C. van Broeckhoven, S. Engelborghs, 2007, Archives of neurology.

Linkage and association studies identify a novel locus for Alzheimer disease at 7q36 in a Dutch population-based sample.

K. Sleegers, C. van Broeckhoven, C. V. van Duijn, 2005, American journal of human genetics.

Progranulin genetic variability contributes to amyotrophic lateral sclerosis

C. Broeckhoven, K. Sleegers, W. Robberecht, 2008, Neurology.

High-density SNP haplotyping suggests altered regulation of tau gene expression in progressive supranuclear palsy.

G. Schellenberg, S. Melquist, D. Dickson, 2005, Human molecular genetics.

Relative contribution of simple mutations vs. copy number variations in five Parkinson disease genes in the Belgian population

C. van Broeckhoven, S. Engelborghs, P. D. De Deyn, 2009, Human mutation.

The C9orf72 repeat size correlates with onset age of disease, DNA methylation and transcriptional downregulation of the promoter

C. Broeckhoven, C. van Broeckhoven, S. Engelborghs, 2015, Molecular Psychiatry.

Early cognitive decline is associated with prion protein codon 129 polymorphism

A. Hofman, J. Houwing-Duistermaat, C. V. van Duijn, 2003, Annals of neurology.

Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration

F. Jessen, G. Frisoni, T. Strom, 2014, Acta Neuropathologica.

Distinct clinical characteristics of C9orf72 expansion carriers compared with GRN, MAPT, and nonmutation carriers in a Flanders-Belgian FTLD cohort.

C. van Broeckhoven, S. Engelborghs, R. Vandenberghe, 2013, JAMA neurology.

TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort

K. Sleegers, C. van Broeckhoven, S. Engelborghs, 2011, Brain : a journal of neurology.

Mutations other than null mutations producing a pathogenic loss of progranulin in frontotemporal dementia

K. Sleegers, C. van Broeckhoven, S. Engelborghs, 2007, Human mutation.

Clinical variability and onset age modifiers in an extended Belgian GRN founder family

B. Bergmans, K. Sleegers, C. van Broeckhoven, 2018, Neurobiology of Aging.

Dose dependent effect of APOE epsilon4 on behavioral symptoms in frontal lobe dementia.

C. van Broeckhoven, S. Engelborghs, P. Mariën, 2006, Neurobiology of aging.

Novel PSEN1 Mutation in a Bulgarian Patient With Very Early-Onset Alzheimer’s Disease, Spastic Paraparesis, and Extrapyramidal Signs

C. van Broeckhoven, M. Cruts, S. Mehrabian, 2009, American journal of Alzheimer's disease and other dementias.

Octapeptide repeat insertions in the prion protein gene and early onset dementia

J. Houwing-Duistermaat, K. Sleegers, C. V. van Duijn, 2004, Journal of Neurology, Neurosurgery & Psychiatry.

Clinical heterogeneity in 3 unrelated families linked to VCP p.Arg159His

S. Engelborghs, R. Vandenberghe, M. Cruts, 2009, Neurology.

Clinical features of TBK1 carriers compared with C9orf72, GRN and non-mutation carriers in a Belgian cohort

C. van Broeckhoven, S. Engelborghs, R. Vandenberghe, 2015, Brain : a journal of neurology.

Genetic contribution of FUS to frontotemporal lobar degeneration

K. Sleegers, C. van Broeckhoven, S. Engelborghs, 2010, Neurology.

alpha-Synuclein promoter confers susceptibility to Parkinson's disease.

M. Farrer, M. Hulihan, S. Lincoln, 2004, Annals of neurology.