Sigal Saphier

发表

A biomimetic platform for studying root-environment interaction

A. Iyer-Pascuzzi, P. Bucki, P. Kumari, 2019, Plant and Soil.

Gastro intestinal tracking and gastric emptying of solid dosage forms in rats using X-ray imaging.

Y. Karton, Sigal Saphier, R. Brandeis, 2010, International journal of pharmaceutics.

Utilizing the CF2H moiety as a H-bond-donating group in drug discovery.

Sigal Saphier, Y. Zafrani, E. Gershonov, 2020, Future medicinal chemistry.

Polysaccharide-thickened aqueous fluoride solutions for rapid destruction of the nerve agent VX. Introducing the opportunity for extensive decontamination scenarios.

Sigal Saphier, I. Columbus, Y. Zafrani, 2014, Environmental science & technology.

Bacterial reduction as means for colonic drug delivery: can other chemical groups provide an alternative to the azo bond?

S. Margel, Sigal Saphier, A. Haft, 2012, Journal of medicinal chemistry.

Difluoromethyl Bioisostere: Examining the "Lipophilic Hydrogen Bond Donor" Concept.

D. Marciano, Sigal Saphier, G. Sod-Moriah, 2017, Journal of medicinal chemistry.

CF2H, a Functional Group-Dependent Hydrogen-Bond Donor: Is It a More or Less Lipophilic Bioisostere of OH, SH, and CH3?

D. Marciano, Sigal Saphier, G. Sod-Moriah, 2019, Journal of medicinal chemistry.

Component mobility by a minute quantity of the appropriate solvent as a principal motif in the acceleration of solid-supported reactions.

D. Marciano, Sigal Saphier, G. Fridkin, 2015, The Journal of organic chemistry.

The Effect of Anesthetic Regimens on Intestinal Absorption of Passively Absorbed Drugs in Rats

Z. Klausner, Sigal Saphier, G. Yacov, 2020, Pharmaceutical Research.

Modulation of the H-Bond Basicity of Functional Groups by α-Fluorine-Containing Functions and its Implications for Lipophilicity and Bioisosterism.

Y. Eichen, A. Pevzner, Sigal Saphier, 2021, Journal of medicinal chemistry.

Studying Lipophilicity Trends of Phosphorus Compounds by 31P-NMR Spectroscopy: A Powerful Tool for the Design of P-Containing Drugs.

Y. Eichen, Z. Klausner, A. Pevzner, 2022, Journal of medicinal chemistry.

Chemoselective N-Difluoromethylation of Functionalized Tertiary Amines.

Sigal Saphier, Y. Zafrani, Moran Madmon, 2016, The Journal of organic chemistry.

Efficient heterogeneous and environmentally friendly degradation of nerve agents on a tungsten-based POM.

Sigal Saphier, D. Mizrahi, I. Columbus, 2010, Journal of hazardous materials.

Novel salicylazo polymers for colon drug delivery: dissolving polymers by means of bacterial degradation.

Y. Karton, Sigal Saphier, 2010, Journal of pharmaceutical sciences.

A biomimetic platform for studying root-environment interaction

A. Iyer-Pascuzzi, P. Bucki, P. Kumari, 2019, Plant and Soil.

Poly(vinyl alcohol)‐methacrylate with CRGD peptide: A photocurable biocompatible hydrogel

O. Shoseyov, Tal Ben-Shalom, E. Epstein, 2021, Journal of tissue engineering and regenerative medicine.

An efficient sol-gel reactor for antibody-catalyzed transformations

E. Keinan, D. Avnir, F. Grynszpan, 1997 .

The Effect of Anesthetic Regimens on Intestinal Absorption of Passively Absorbed Drugs in Rats

Z. Klausner, Sigal Saphier, G. Yacov, 2020, Pharmaceutical Research.

Species-specific lipophilicities of fluorinated diketones in complex equilibria systems and their potential as multifaceted reversible covalent warheads

Y. Eichen, Sigal Saphier, Galit Parvari, 2023, Communications chemistry.

Placing CF2 in the Center: Major Physicochemical Changes Upon a Minor Structural Alteration in Gem-Difunctional Compounds.

Y. Eichen, A. Pevzner, Sigal Saphier, 2022, Chemistry.

Gastro intestinal tracking and gastric emptying of solid dosage forms in rats using X-ray imaging.

Y. Karton, Sigal Saphier, R. Brandeis, 2010, International journal of pharmaceutics.

Addressing the Opioids Lipophilicity Challenge via a Straightforward and Simultaneous 1H NMR-Based logP/D Determination, Both Separately and in Mixtures.

Y. Eichen, Sigal Saphier, Galit Parvari, 2024, Journal of medicinal chemistry.