Ellen Sapp

Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease

N. Aronin, E. Sapp, K. Chase, 2009, Neurobiology of Disease.

Mutant Huntingtin Impairs Vesicle Formation from Recycling Endosomes by Interfering with Rab11 Activity

Kevin Fogarty, Lawrence M. Lifshitz, Clive Standley, 2009, Molecular and Cellular Biology.

Mutant Huntingtin Fragments Form Oligomers in a Polyglutamine Length-dependent Manner in Vitro and in Vivo*

Leslie M Thompson, Justin Legleiter, L. Thompson, 2010, The Journal of Biological Chemistry.

Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis

Z. Qin, N. Aronin, E. Sapp, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

R. Carraway, J. Vonsattel, C. Schwarz, 1995, Neuron.

Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing.

Anastasia Khvorova, Lakshmi Raj, Reka A Haraszti, 2016, Molecular therapy : the journal of the American Society of Gene Therapy.

Aberrant Rab11-Dependent Trafficking of the Neuronal Glutamate Transporter EAAC1 Causes Oxidative Stress and Cell Death in Huntington's Disease

N. Aronin, E. Sapp, Marian DiFiglia, 2010, The Journal of Neuroscience.

Huntingtin cleavage product A forms in neurons and is reduced by gamma-secretase inhibitors

Dimitri Krainc, D. Curtis, D. Krainc, 2010, Molecular Neurodegeneration.

CAG expansion affects the expression of mutant huntingtin in the Huntington's disease brain

Nahida Matta, J. Penney, A. Young, 1995, Neuron.

Wild-Type and Mutant Huntingtins Function in Vesicle Trafficking in the Secretory and Endocytic Pathways

C. Schwarz, J. Velier, Manho Kim, 1998, Experimental Neurology.