C F Barbas

发表

Custom DNA-binding proteins come of age: polydactyl zinc-finger proteins.

D J Segal, C. Barbas, C. Barbas, 2001, Current opinion in biotechnology.

A binary plasmid system for shuffling combinatorial antibody libraries.

D R Burton, C. Barbas, R. Lerner, 1992, Proceedings of the National Academy of Sciences of the United States of America.

CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range.

D R Burton, C. Barbas, D. Burton, 1995, Journal of molecular biology.

Synergistic neutralization of a chimeric SIV/HIV type 1 virus with combinations of human anti-HIV type 1 envelope monoclonal antibodies or hyperimmune globulins.

D R Burton, C. Barbas, J. Sodroski, 1997, AIDS research and human retroviruses.

In vitro antigen challenge of human antibody libraries for vaccine evaluation: the human immunodeficiency virus type 1 envelope

D R Burton, H J Ditzel, J. Binley, 1996, Journal of virology.

A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals.

D R Burton, C. Barbas, R. Lerner, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Aldol sensors for the rapid generation of tunable fluorescence by antibody catalysis.

B List, C. Barbas, R. Lerner, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks.

D J Segal, C. Barbas, D. Segal, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Surface plasmon resonance based kinetic studies of zinc finger-DNA interactions.

C. Barbas, H. Wu, H Wu, 1995, Journal of immunological methods.

Immune Versus Natural Selection : Antibody Aldolases with Enzymic Rates But Broader Scope

A Heine, B List, C. Barbas, 2022 .

High-affinity self-reactive human antibodies by design and selection: targeting the integrin ligand binding site.

J W Smith, C. Barbas, L. Languino, 1993, Proceedings of the National Academy of Sciences of the United States of America.

In vitro evolution of a neutralizing human antibody to human immunodeficiency virus type 1 to enhance affinity and broaden strain cross-reactivity.

D R Burton, R. M. Hendry, C. Barbas, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Design of polydactyl zinc-finger proteins for unique addressing within complex genomes.

D J Segal, C. Barbas, D. Segal, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Antibodies without immunization.

D R Burton, C. Barbas, R. Lerner, 1992, Science.

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences.

D J Segal, C. Barbas, D. Segal, 1999, Proceedings of the National Academy of Sciences of the United States of America.

In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library.

C. Barbas, R. Lerner, Angray S. Kang, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1

D R Burton, C. Barbas, J. Sodroski, 1994, Journal of virology.

Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries.

D R Burton, C. Barbas, D. Burton, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Positive and negative regulation of endogenous genes by designed transcription factors.

C. Barbas, R. Beerli, B. Dreier, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Human antibodies to HIV-1 by recombinant DNA methods.

D R Burton, C F Barbas, 1993, Chemical immunology.

Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity.

D R Burton, C. Barbas, D. Burton, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Recombinant human monoclonal antibody IgG1b12 neutralizes diverse human immunodeficiency virus type 1 primary isolates.

E A Emini, D R Burton, C. Barbas, 1997, AIDS research and human retroviruses.

Human antibodies from combinatorial libraries.

D R Burton, C. Barbas, D. Burton, 1994, Advances in immunology.

Neutralizing recombinant human antibodies to a conformational V2- and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure.

D R Burton, H J Ditzel, R. M. Hendry, 1995, Journal of immunology.

Development of Zinc Finger Domains for Recognition of the 5′-ANN-3′ Family of DNA Sequences and Their Use in the Construction of Artificial Transcription Factors*

D J Segal, C. Barbas, D. Segal, 2001, The Journal of Biological Chemistry.

Methods for the generation of chicken monoclonal antibody fragments by phage display.

R. Fuller, C. Barbas, P. Steinberger, 2000, Journal of immunological methods.

Recombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitro.

C. Barbas, F. Chiodi, E. Norrby, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Molecular profile of an antibody response to HIV-1 as probed by combinatorial libraries.

G R Pilkington, C. Barbas, N. Haigwood, 1993, Journal of molecular biology.

Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces.

C. Barbas, R. Lerner, S. Benkovic, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problem.

C. Barbas, R. Lerner, D. Hoekstra, 1992, Proceedings of the National Academy of Sciences of the United States of America.

On the use of combinatorial antibody libraries to clone the "fossil record" of an individual's immune response.

D R Burton, C. Barbas, R. Lerner, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Design of novel sequence-specific DNA-binding proteins.

D J Segal, C. Barbas, D. Segal, 2000, Current opinion in chemical biology.

Direct selection of antibodies that coordinate metals from semisynthetic combinatorial libraries.

C. Barbas, R. Lerner, J. Rosenblum, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Phage display of combinatorial antibody libraries.

C. Barbas, C F Barbas, C. Rader, 1997, Current opinion in biotechnology.

Efficient Aldolase Catalytic Antibodies That Use the Enamine Mechanism of Natural Enzymes

R. Lerner, C. Barbas, C F Barbas, 1995, Science.

Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task.

A Heine, B List, R. Fuller, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Human immunodeficiency virus type 1 mutants that escape neutralization by human monoclonal antibody IgG1b12. off

D R Burton, C. Barbas, J. Moore, 1997, Journal of virology.

Human combinatorial antibody libraries to hepatitis B surface antigen.

D R Burton, C. Barbas, R. Lerner, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains.

D J Segal, C. Barbas, D. Segal, 2000, Journal of molecular biology.

Generation and Characterization of a Recombinant Human CCR5-specific Antibody

C. Barbas, P. Steinberger, C F Barbas, 2000, The Journal of Biological Chemistry.

Recombinant human respiratory syncytial virus (RSV) monoclonal antibody Fab is effective therapeutically when introduced directly into the lungs of RSV-infected mice.

D R Burton, C. Barbas, D. Burton, 1994, Proceedings of the National Academy of Sciences of the United States of America.