J E Savage

2-Substituted tryptamines: agents with selectivity for 5-HT(6) serotonin receptors.

B. Roth, S. Hufeisen, R. Glennon, 2000, Journal of medicinal chemistry.

Evidence for Possible Involvement of 5-HT2B Receptors in the Cardiac Valvulopathy Associated With Fenfluramine and Other Serotonergic Medications

B. Roth, S. Hufeisen, J. Savage, 2000, Circulation.

A highly conserved aspartic acid (Asp-155) anchors the terminal amine moiety of tryptamines and is involved in membrane targeting of the 5-HT(2A) serotonin receptor but does not participate in activation via a "salt-bridge disruption" mechanism.

B. Roth, R. Glennon, W. Kroeze, 2000, The Journal of pharmacology and experimental therapeutics.