Linda O Elliott

Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP).

M. Distefano, W. Fairbrother, K. Deshayes, 2003, Biochemistry.

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis.

Vishva M Dixit, V. Dixit, J. Blankenship, 2007, Cell.

Orally bioavailable antagonists of inhibitor of apoptosis proteins based on an azabicyclooctane scaffold.

Vickie Tsui, Frederick Cohen, Harvey Wong, 2009, Journal of medicinal chemistry.

Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.

K. Das, G. Salvesen, W. Fairbrother, 2005, The Biochemical journal.

Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).

Zhaoyang Wen, Brigitte Maurer, Vickie Tsui, 2012, Journal of medicinal chemistry.