Wayne J Fairbrother

发表

Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP).

M. Distefano, W. Fairbrother, K. Deshayes, 2003, Biochemistry.

Exploring Protein–Protein Interactions with Phage Display

Sachdev S Sidhu, S. Sidhu, W. Fairbrother, 2003, Chembiochem : a European journal of chemical biology.

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis.

Vishva M Dixit, V. Dixit, J. Blankenship, 2007, Cell.

c-IAP1 and c-IAP2 Are Critical Mediators of Tumor Necrosis Factor α (TNFα)-induced NF-κB Activation*

W. Fairbrother, K. Deshayes, K. Zobel, 2008, Journal of Biological Chemistry.

Orally bioavailable antagonists of inhibitor of apoptosis proteins based on an azabicyclooctane scaffold.

Vickie Tsui, Frederick Cohen, Harvey Wong, 2009, Journal of medicinal chemistry.

ICEBERG A Novel Inhibitor of Interleukin-1β Generation

Vishva M Dixit, V. Dixit, S. Shriver, 2000, Cell.

Structure of IL-33 and its interaction with the ST2 and IL-1RAcP receptors--insight into heterotrimeric IL-1 signaling complexes.

Andreas Lingel, Thomas M Weiss, Christian Wiesmann, 2009, Structure.

Convergent recognition of the IgE binding site on the high-affinity IgE receptor.

Charles Eigenbrot, G. Nakamura, C. Eigenbrot, 2004, Structure.

The Inhibitor of Apoptosis Proteins as Therapeutic Targets in Cancer

W. Fairbrother, D. Vučić, Domagoj Vucic, 2007, Clinical Cancer Research.

Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.

K. Das, G. Salvesen, W. Fairbrother, 2005, The Biochemical journal.

Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).

Zhaoyang Wen, Brigitte Maurer, Vickie Tsui, 2012, Journal of medicinal chemistry.