J. Studts

发表

Microchip zone electrophoresis for high-throughput analysis of monoclonal antibody charge variants.

T. Wheeler, Jingfu Sun, S. Pleiner, 2014, Analytical chemistry.

Cross‐scale quality assessment of a mechanistic cation exchange chromatography model

G. Wang, J. Hubbuch, J. Studts, 2020, Biotechnology progress.

Crystal structures and functional studies of T4moD, the toluene 4-monooxygenase catalytic effector protein.

B. Fox, A. Orville, J. Studts, 2005, Biochemistry.

Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase.

B. Fox, R. Steffan, J. Studts, 1997, Biochemistry.

Aromatic hydroxylation catalyzed by toluene 4-monooxygenase in organic solvent/aqueous buffer mixtures

B. Fox, J. Dordick, J. Studts, 2001, Applied biochemistry and biotechnology.

Introduction and clearance of beta‐glucan in the downstream processing of monoclonal antibodies

J. Studts, Simon Kluters, Karin Steinhauser, 2021, Biotechnology progress.

Recombinant toluene-4-monooxygenase: catalytic and Mössbauer studies of the purified diiron and rieske components of a four-protein complex.

B. Fox, R. Steffan, J. Studts, 1996, Biochemistry.

Prediction and Reduction of the Aggregation of Monoclonal Antibodies

F. Rousseau, A. Gils, P. Schulz, 2017, Journal of molecular biology.

Integrated process model for the prediction of biopharmaceutical manufacturing chromatography and adjustment steps.

J. Hubbuch, Till Briskot, J. Studts, 2022, Journal of chromatography. A.

Optimized expression and purification of toluene 4-monooxygenase hydroxylase.

B. Fox, R. Steffan, J. Studts, 2000, Protein expression and purification.

Integrated Process Model Applications Linking Bioprocess Development to Quality by Design Milestones

C. Herwig, T. Zahel, J. Studts, 2021, Bioengineering.

Development of a High-Throughput Assay to Measure Histidine Decarboxylase Activity

Elda Gautschi, L. Patnaude, J. Studts, 2006, Journal of biomolecular screening.

Structural Basis of Chemokine Sequestration by a Herpesvirus Decoy Receptor

Tracy M. Handel, Daved H. Fremont, C. Nelson, 2002, Cell.

Structural Basis of Constitutive Activity and a Unique Nucleotide Binding Mode of Human Pim-1 Kinase*

Jun Li, B. Farmer, K. Qian, 2005, Journal of Biological Chemistry.

Crystallization and preliminary analysis of xenobiotic reductase A and ligand complexes from Pseudomonas putida II-B.

B. Fox, G. Chambliss, A. Orville, 2004, Acta crystallographica. Section D, Biological crystallography.

Oncogenic potential of the DNA replication licensing protein CDT1

D. Fremont, Kyunghee Choi, E. Moon, 2002, Oncogene.

Molecular basis of MAPK-activated protein kinase 2:p38 assembly

Bennett T. Farmer, B. Farmer, C. Pargellis, 2007, Proceedings of the National Academy of Sciences.

Expression, purification, crystallization and preliminary crystallographic analysis of human Pim-1 kinase.

B. Farmer, K. Qian, K. Barringer, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Modeling the Gibbs-Donnan effect during ultrafiltration and diafiltration processes using the Poisson–Boltzmann theory in combination with a basic Stern model

J. Hubbuch, Till Briskot, J. Studts, 2022, Journal of Membrane Science.

Boosting antibody developability through rational sequence optimization

Daniel Seeliger, Patrick Garidel, Michaela Blech, 2015, mAbs.

Mass spectrometric evaluation of upstream and downstream process influences on host cell protein patterns in biopharmaceutical products

T. Schwab, D. Waldera-Lupa, K. Krapfenbauer, 2019, Biotechnology progress.

The impact of endotoxin masking on the removal of endotoxin during manufacturing of a biopharmaceutical drug product.

S. Combe, J. Studts, M. Nägele, 2022, Journal of Chromatography A.

Combined participation of hydroxylase active site residues and effector protein binding in a para to ortho modulation of toluene 4-monooxygenase regiospecificity.

B. Fox, J. Studts, Kevin H. Mitchell, 2002, Biochemistry.

Threonine 201 in the diiron enzyme toluene 4-monooxygenase is not required for catalysis.

B. Fox, R. Steffan, J. Studts, 2000, Biochemistry.

In-line product quality monitoring during biopharmaceutical manufacturing using computational Raman spectroscopy

G. Wang, J. Studts, Jiarui Wang, 2023, mAbs.

A multiscale modeling method for therapeutic antibodies in ion exchange chromatography

T. Schwab, J. Hubbuch, Jan-Hendrik Grosch, 2022, Biotechnology and bioengineering.

Modeling the impact of amino acid substitution in a monoclonal antibody on cation exchange chromatography

M. Blech, J. Hubbuch, J. Studts, 2021, Biotechnology and bioengineering.

In silico process characterization for biopharmaceutical development following the quality by design concept

G. Wang, J. Hubbuch, J. Studts, 2021, Biotechnology progress.

Analysis of complex protein elution behavior in preparative ion exchange processes using a colloidal particle adsorption model.

G. Wang, G. Malmquist, J. Hubbuch, 2021, Journal of chromatography. A.

Straightforward method for calibration of mechanistic cation exchange chromatography models for industrial applications.

Gang Wang, Jürgen Hubbuch, David Saleh, 2020, Biotechnology progress.

Modeling of biopharmaceutical UF/DF from laboratory to manufacturing scale

J. Hubbuch, Till Briskot, J. Studts, 2023, Comput. Chem. Eng..

Connected mechanistic process modeling to predict a commercial biopharmaceutical downstream process

J. Hubbuch, Till Briskot, J. Studts, 2023, Computers and Chemical Engineering.

Solution structure of the toluene 4-monooxygenase effector protein (T4moD).

B. Fox, J. Markley, J. Studts, 2001, Biochemistry.

Crystallization and preliminary analysis of native and N-terminal truncated isoforms of toluene-4-monooxygenase catalytic effector protein.

B. Fox, A. Orville, J. Studts, 2003, Acta crystallographica. Section D, Biological crystallography.