H. Väänänen

P. Laippala, S. Kivelä, H. Luukinen, 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Downregulation of Small GTPase Rab7 Impairs Osteoclast Polarization and Bone Resorption* 210

V. Parikka, H. Väänänen, Haibo Zhao, 2001, The Journal of Biological Chemistry.

The regulation of pHi in osteoclasts is dependent on the culture substrate and on the stage of the resorption cycle.

P. Lehenkari, H. Väänänen, T. Linna, 1997, Biochemical and biophysical research communications.

Spatial organization of microfilaments and vitronectin receptor, alpha v beta 3, in osteoclasts. A study using confocal laser scanning microscopy.

M. Horton, M. Helfrich, H. Väänänen, 1993, Journal of cell science.

Estrogen responsiveness of bone formation in vitro and altered bone phenotype in aged estrogen receptor-alpha-deficient male and female mice.

J. Risteli, V. Parikka, P. Härkönen, 2005, European journal of endocrinology.

The Critical Role of IL-34 in Osteoclastogenesis

K. Buki, H. Väänänen, Zhi Chen, 2011, PloS one.

Tartrate-resistant acid phosphatase 5b (TRACP 5b) as a marker of bone resorption.

H. Väänänen, J. Halleen, S. Tiitinen, 2006, Clinical laboratory.

The effects of acute hyperinsulinemia on bone metabolism

H. Koistinen, P. Nuutila, M. Bucci, 2015, Endocrine connections.

Serum osteocalcin is not associated with glucose but is inversely associated with leptin across generations of nondiabetic women.

T. Törmäkangas, M. Alen, H. Tian, 2012, The Journal of clinical endocrinology and metabolism.

Influence of estrogen-progestin replacement therapy and exercise on lumbar spine mobility and low back symptoms in a healthy early postmenopausal female population: a 2-year randomized controlled trial

J. Heikkinen, H. Väänänen, E. Kyllönen, 1998, European Spine Journal.

Breast cancer cells with inhibition of p38α have decreased MMP-9 activity and exhibit decreased bone metastasis in mice

E. Rosenthal, H. Väänänen, C. Suarez‐Cuervo, 2004, Clinical & Experimental Metastasis.

Short‐Term Intravenous Bisphosphonates in Prevention of Postmenopausal Bone Loss

J. Heikkinen, K. Laitinen, H. Väänänen, 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Evidence for the role of osteocytes in the initiation of targeted remodeling.

H. Higaki, K. Kurata, T. Heino, 2009, Technology and health care : official journal of the European Society for Engineering and Medicine.

Death of osteocytes turns off the inhibition of osteoclasts and triggers local bone resorption.

T. Hentunen, H. Väänänen, M. Mulari, 2005, Biochemical and biophysical research communications.

Estrogen and bone metabolism.

P. Härkönen, H. Väänänen, 1996, Maturitas.

Carbonic anhydrase III as a serum marker for diagnosis of rhabdomyolysis.

K. Huttunen, H. Väänänen, H. Syrjälä, 1990, Clinical chemistry.

Influence of estrogen-progestin treatment on back pain and disability among slim premenopausal women with low lumbar spine bone mineral density. A 2-year placebo-controlled randomized trial.

J. Heikkinen, H. Väänänen, E. Kyllönen, 1999, Spine.

Estrogen and the selective estrogen receptor modulator (SERM) protection against cell death in estrogen receptor alpha and beta expressing U2OS cells

T. Guo, L. Kangas, P. Härkönen, 2008, Molecular and Cellular Endocrinology.

Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro

L. Kangas, P. Härkönen, T. Hentunen, 2007, British journal of pharmacology.

A Novel Immunoassay for The Determination of Tartrate‐Resistant Acid Phosphatase 5b From Rat Serum

P. Vihko, H. Väänänen, J. Halleen, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Urinary osteocalcin as a marker of bone metabolism.

P. Gerdhem, S. Käkönen, K. Pettersson, 2005, Clinical chemistry.

Alteration in the Mechanical Competence and Structural Properties in the Femoral Neck and Vertebrae of Ovariectomized Rats

J. Tuukkanen, H. Väänänen, Z. Peng, 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Calcitonin promotes osteoclast survival in vitro

P. Härkönen, J. Mönkkönen, E. Valve, 1996, Molecular and Cellular Endocrinology.

Calcitonin, prostaglandin E2, and dibutyryl cyclic adenosine 3',5'-monophosphate disperse the specific microfilament structure in resorbing osteoclasts.

Paivi, H. Väänänen, P. Lakkakorpi, 1990, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Associations Between Homocysteine, Bone Turnover, BMD, Mortality, and Fracture Risk in Elderly Women

P. Gerdhem, K. Pettersson, A. Isaksson, 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Biochemical markers of bone turnover are influenced by recently sustained fracture.

P. Gerdhem, K. Pettersson, K. Obrant, 2005, Bone.

Bone-resorbing osteoclasts reveal a dynamic division of basal plasma membrane into two different domains.

J. Salo, P. Lehenkari, K. Metsikkö, 1996, Journal of cell science.

Effect of running exercise on the bone loss induced by orchidectomy in the rat

J. Tuukkanen, H. Väänänen, Z. Peng, 1994, Calcified Tissue International.

Osteoclast-derived serum tartrate-resistant acid phosphatase 5b in Albers-Schonberg disease (type II autosomal dominant osteopetrosis).

M. Econs, S. Waguespack, H. Väänänen, 2004, Clinical chemistry.

Serum Tartrate-Resistant Acid Phosphatase 5b, but not 5a, Correlates with Other Markers of Bone Turnover and Bone Mineral Density

H. Suominen, J. Heikkinen, H. Väänänen, 2002, Calcified Tissue International.

Removal of osteoclast bone resorption products by transcytosis.

P. Lehenkari, P. Lehenkari, K. Metsikkö, 1997, Science.

Estrogen protects primary osteocytes against glucocorticoid-induced apoptosis

P. Härkönen, T. Hentunen, H. Väänänen, 2005, Apoptosis.

Omeprazole, a specific inhibitor of H+−K+-ATPase, inhibits bone resorptionin vitro

J. Tuukkanen, H. Väänänen, Juha Tuukkanen, 1986, Calcified Tissue International.

Conditioned medium of estrogen-treated osteoblasts inhibits osteoclast maturation and function in vitro.

P. Härkönen, J. Mönkkönen, H. Väänänen, 1999, Bone.

Intracellular Machinery for Matrix Degradation in Bone‐Resorbing Osteoclasts

P. Vihko, H. Väänänen, J. Halleen, 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The Effect of Oral Glucose Tolerance Test on Serum Osteocalcin and Bone Turnover Markers in Young Adults

O. Mäkitie, E. Kajantie, S. Andersson, 2011, Calcified Tissue International.

Characterization of Serum Tartrate‐Resistant Acid Phosphatase and Development of a Direct Two‐Site Immunoassay

M. Karp, S. Käkönen, K. Pettersson, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A Dual‐Label Immunofluorometric Assay for Human Osteocalcin

M. Karp, S. Käkönen, K. Pettersson, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Epitope mapping of nine monoclonal antibodies against osteocalcin: Combinations into two‐site assays affect both assay specificity and sample stability

M. Karp, S. Käkönen, K. Pettersson, 1996, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Ovariectomy-Induced Bone Loss Can be Affected by Different Intensities of Treadmill Running Exercise in Rats

J. Tuukkanen, H. Väänänen, Z. Peng, 1997, Calcified Tissue International.

Overexpression of Human Hydroxysteroid (17β) Dehydrogenase 2 Induces Disturbance in Skeletal Development in Young Male Mice

M. Poutanen, H. Väänänen, Zhongyi Shen, 2008, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Estrogen and Testosterone Use Different Cellular Pathways to Inhibit Osteoclastogenesis and Bone Resorption

P. Härkönen, T. Hentunen, H. Väänänen, 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Osteoclast recruiting activity in bone matrix.

O. Vuolteenaho, T. Hentunen, H. Väänänen, 1994, Bone and mineral.

Serum carbonic anhydrase III and myoglobin concentrations in acute myocardial infarction.

T. Takala, V. Myllylä, H. Väänänen, 1990, Clinical chemistry.

Intracellular Fragmentation of Bone Resorption Products by Reactive Oxygen Species Generated by Osteoclastic Tartrate-resistant Acid Phosphatase*

P. Lehenkari, P. Lehenkari, S. Reddy, 1999, The Journal of Biological Chemistry.

Intracellular membrane trafficking pathways in bone-resorbing osteoclasts revealed by cloning and subcellular localization studies of small GTP-binding rab proteins.

H. Väänänen, O. Ettala, Haibo Zhao, 2002, Biochemical and biophysical research communications.

Localization of Carbonic Anhydrase Isozymes in Calcified Tissues

H. Väänänen, E. Parvinen, 1991 .

Successful treatment of the post-traumatic osteolysis of distal clavicle with alendronate

K. Mattila, K. Parkkola, H. Väänänen, 2006 .

Tartrate-resistant acid phosphatase 5B circulates in human serum in complex with alpha2-macroglobulin and calcium.

P. Vihko, H. Väänänen, J. Halleen, 2003, Biochemical and biophysical research communications.

Tartrate‐Resistant Acid Phosphatase 5b: A Novel Serum Marker of Bone Resorption

H. Suominen, H. Väänänen, J. Halleen, 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Inhibition of intravacuolar acidification by antisense RNA decreases osteoclast differentiation and bone resorption in vitro.

C. Löwik, H. Väänänen, S. Papapoulos, 1999, Journal of cell science.

Overexpression of cathepsin K accelerates the resorption cycle and osteoblast differentiation in vitro.

E. Vuorio, R. Kiviranta, H. Väänänen, 2009, Bone.

Pathogenesis of osteoporosis

H. Väänänen, 2007, Calcified Tissue International.

Serum tartrate-resistant acid phosphatase 5b is a specific and sensitive marker of bone resorption.

M. Seibel, H. Woitge, H. Väänänen, 2001, Clinical chemistry.

Characterization of High-density Apolipoprotein Particles A-i and A-i:a-ii Isolated from Humans with Cholesteryl Ester Transfer Protein Deficiency. Eur Serum Tartrate-resistant Acid Phosphatase 5b Is a Spe- Cific and Sensitive Marker Of

M. Seibel, H. Woitge, H. Väänänen, 2022 .

Inhibition of the osteoclast V‐ATPase by small interfering RNAs

Yingwei Hu, Pirkko Muhonen, H. Väänänen, 2005, FEBS letters.

COMMENTARY The cell biology of osteoclast function

H. Väänänen, J. Halleen, M. Mulari, 2000 .

Rapid screening method for osteoclast differentiation in vitro that measures tartrate-resistant acid phosphatase 5b activity secreted into the culture medium.

J. Mönkkönen, T. Hentunen, H. Väänänen, 2000, Clinical chemistry.

Can Elevated Serum Tracp-5B Levels Predict Stress Fractures? A Cohort Study

H. Pihlajamäki, H. Väänänen, M. Mulari, 2009, Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society.

Recombinant VSV G proteins reveal a novel raft-dependent endocytic pathway in resorbing osteoclasts.

Yi Sun, K. Metsikkö, H. Väänänen, 2008, Experimental cell research.

Improved methods for testing antiresorptive compounds in human osteoclast cultures

H. Väänänen, J. Rissanen, J. Halleen, 2008, Journal of Bone and Mineral Metabolism.

Sequence and TLR9 independent increase of TRACP expression by antisense DNA and siRNA molecules.

S. Avnet, Pirkko Muhonen, H. Väänänen, 2007, Biochemical and biophysical research communications.

Effects of proteolysis and reduction on phosphatase and ROS-generating activity of human tartrate-resistant acid phosphatase.

O. Mäentausta, S. Hamilton, H. Väänänen, 2006, Archives of biochemistry and biophysics.

Serum TRACP 5b Is a Useful Marker for Monitoring Alendronate Treatment: Comparison With Other Markers of Bone Turnover

T. Lehtimäki, P. Kannus, I. Vuori, 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Macrophages overexpressing tartrate-resistant acid phosphatase show altered profile of free radical production and enhanced capacity of bacterial killing.

D. Hume, A. Cassady, H. Väänänen, 2005, Biochemical and biophysical research communications.

Characteristics of clodronate-induced apoptosis in osteoclasts and macrophages.

P. Härkönen, J. Mönkkönen, H. Väänänen, 1996, Molecular pharmacology.

Comparison of muscle strength and bone mineral density in healthy postmenopausal women. A cross-sectional population study.

J. Heikkinen, H. Väänänen, E. Kyllönen, 2020, Scandinavian journal of rehabilitation medicine.

Endocytic pathway from the basal plasma membrane to the ruffled border membrane in bone-resorbing osteoclasts.

H. Väänänen, H. Palokangas, M. Mulari, 1997, Journal of cell science.

Novel perspectives on the transcytotic route in osteoclasts

H. Väänänen, M. Mulari, P. Lakkakorpi, 2013, BoneKEy reports.

Cystatin B as an intracellular modulator of bone resorption.

A. Rinne, P. Saukko, R. Rinne, 2006, Matrix biology : journal of the International Society for Matrix Biology.

Pharmacological Sequestration of Intracellular Cholesterol in Late Endosomes Disrupts Ruffled Border Formation in Osteoclasts

H. Väänänen, Haibo Zhao, H Kalervo Väänänen, 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Osteoblast-like Cells Complete Osteoclastic Bone Resorption and Form New Mineralized Bone Matrix In Vitro

P. Härkönen, H. Väänänen, M. Mulari, 2004, Calcified Tissue International.

Potential Function for the ROS‐Generating Activity of TRACP

H. Väänänen, J. Halleen, S. Alatalo, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Identification of novel proteolytic forms of osteocalcin in human urine.

P. Gerdhem, S. Käkönen, K. Pettersson, 2003, Biochemical and biophysical research communications.

Tartrate-resistant acid phosphatase facilitates hydroxyl radical formation and colocalizes with phagocytosed Staphylococcus aureus in alveolar macrophages.

V. Parikka, H. Väänänen, J. Halleen, 2001, Biochemical and biophysical research communications.

Two‐Site Immunoassays for Osteoclastic Tartrate‐Resistant Acid Phosphatase Based on Characterization of Six Monoclonal Antibodies

M. Karp, Pirjo Laaksonen, S. Käkönen, 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

How do osteoclasts resorb bone

Yin-kun Liu, P. Lehenkari, H. Väänänen, 1998 .

Carbonic anhydrases in calcified tissues.

P. Härkönen, T. Hentunen, H. Väänänen, 2000, EXS.

Carbonic anhydrase isoenzymes in isolated rat peripheral monocytes, tissue macrophages, and osteoclasts.

M. Leppilampi, H. Väänänen, K. Sundquist, 1987, Bone.

The effects of bisphosphonates on the resorption cycle of isolated osteoclasts

P. Lehenkari, H. Väänänen, K. Selander, 1994, Calcified Tissue International.

Carbonic anhydrase II plays a major role in osteoclast differentiation and bone resorption by effecting the steady state intracellular pH and Ca2+.

P. Lehenkari, J. Tuukkanen, T. Hentunen, 1998, Experimental cell research.

A study using confocal laser scanning microscopy

M. Horton, M. Helfrich, H. Väänänen, 1993 .

Spatial organization of microfilaments and vitronectin receptor , v 3 , in osteoclasts A study using confocal laser scanning microscopy

M. Horton, M. Helfrich, H. Väänänen, 2022 .

The cell biology of osteoclast function.

H. Väänänen, J. Halleen, M. Mulari, 2000, Journal of cell science.

Osteoclast Ruffled Border Has Distinct Subdomains for Secretion and Degraded Matrix Uptake

H. Väänänen, M. Mulari, Haibo Zhao, 2003, Traffic.

Beta 1 integrins and osteoclast function: involvement in collagen recognition and bone resorption.

M. Horton, S. Nesbitt, D. Mendrick, 1996, Bone.

Myoglobin/carbonic anhydrase III ratio: highly specific and sensitive early indicator for myocardial damage in acute myocardial infarction.

H. Väänänen, H. Syrjälä, J. Vuori, 1996, Clinical chemistry.

The use of myoglobin/carbonic anhydrase III ratio as a marker for myocardial damage in patients with renal failure.

K. Huttunen, H. Väänänen, J. Vuori, 1997, Clinica chimica acta; international journal of clinical chemistry.

Demonstration of the Predominant Urine Osteocalcin Fragments Detectable by Two‐Site Immunoassays

M. Karp, S. Käkönen, K. Pettersson, 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Estrogen enhances differentiation of osteoblasts in mouse bone marrow culture.

P. Härkönen, M. Perälä-Heape, J. Salo, 1998, Bone.

Consecutive expression of carbonic anhydrase isoenzymes during development of rat liver and skeletal muscle differentiation.

J. Slot, H. Väänänen, E. Parvinen, 1989, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

The mechanical strength of bone in different rat models of experimental osteoporosis.

T. Jämsä, J. Tuukkanen, H. Väänänen, 1994, Bone.

Phosphatase and oxygen radical-generating activities of mammalian purple acid phosphatase are functionally independent.

G. Schneider, Y. Lindqvist, P. Vihko, 2002, Biochemical and biophysical research communications.

Role of fibroblast growth factor receptors (FGFR) and FGFR like-1 (FGFRL1) in mesenchymal stromal cell differentiation to osteoblasts and adipocytes

P. Härkönen, H. Väänänen, K. Ivaska, 2017, Molecular and Cellular Endocrinology.

Transient 100 nM dexamethasone treatment reduces inter- and intraindividual variations in osteoblastic differentiation of bone marrow-derived human mesenchymal stem cells.

H. Aro, J. Alm, T. Hentunen, 2012, Tissue engineering. Part C, Methods.

Inhibition of bone resorption in vitro by antisense RNA and DNA molecules targeted against carbonic anhydrase II or two subunits of vacuolar H(+)-ATPase.

H. Väänänen, T. Laitala, Tiina, 1994, The Journal of clinical investigation.

Regulation of tartrate resistant acid phosphatase (Trap) in osteoclasts

H. Väänänen, 2001 .

Studies on the protein tyrosine phosphatase activity of tartrate-resistant acid phosphatase.

P. Vihko, H. Väänänen, J. Stepan, 1998, Archives of biochemistry and biophysics.

Presence and specific concentration of carbonic anhydrase II in matrix vesicles.

H. Anderson, D. Morris, D. Stechschulte, 1992, Bone and mineral.

Quantification of carbonic anhydrase III and myoglobin in different fiber types of human psoas muscle

T. Takala, S. Rasi, H. Väänänen, 2004, Histochemistry.

Immobilization induces carbonic anhydrase III in type II fibers of rat skeletal muscle.

T. Takala, S. Jeffery, H. Väänänen, 1991, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Cytoskeletal changes in osteoclasts during the resorption cycle

H. Väänänen, P. Lakkakorpi, H. Kalervo Väänänen, 1996, Microscopy research and technique.

Serum tartrate-resistant acid phosphatase 5b (TRACP 5b) as a marker of skeletal changes in prostate cancer

E. Salminen, H. Väänänen, J. Halleen, 2005, Acta oncologica.

Long-term effects of ovariectomy on the mechanical properties and chemical composition of rat bone.

J. Tuukkanen, H. Väänänen, Z. Peng, 1997, Bone.

Calcification of cartilage matrix in chondrocyte cultures derived from rachitic rat growth plate cartilage.

H. Anderson, D. Morris, H. Väänänen, 1983, Metabolic bone disease & related research.

Resorption-cycle-dependent polarization of mRNAs for different subunits of V-ATPase in bone-resorbing osteoclasts.

G. E. Dean, M. Howell, H. Väänänen, 1996, Molecular biology of the cell.

Purification of vacuolar ATPase with bafilomycin C1 affinity chromatography.

A. Koskinen, H. Väänänen, T. Rautiala, 1993, Biochemical and biophysical research communications.

Purification and localization of human carbonic anhydrase

H. Väänänen, M. Paloniemi, J. Vuori, 2004, Histochemistry.

Effect of impact exercise on bone metabolism

R. Korpelainen, J. Leppäluoto, T. Jämsä, 2009, Osteoporosis International.

A Rationale for Osteoclast Selectivity of Inhibiting the Lysosomal V-ATPase a3 Isoform

H. Väänänen, J. Nyman, Jonas Nyman, 2010, Calcified Tissue International.

Differential regulation of carbonic anhydrase II by androgen and estrogen in dorsal and lateral prostate of the rat.

P. Härkönen, S. Mäkelä, E. Valve, 1991, Endocrinology.

Effects of recombinant human osteogenic protein-1 on the differentiation of osteoclast-like cells and bone resorption.

P. Lehenkari, J. Tuukkanen, T. Hentunen, 1995, Biochemical and biophysical research communications.

Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite.

I. Hassinen, P. Lehenkari, J. Mönkkönen, 2002, Molecular pharmacology.

Immunohistochemical localization of alkaline phosphatase in the chicken epiphyseal growth cartilage

H. Väänänen, 1980, Histochemistry.

Mesenchymal stem cells.

H. Väänänen, 2005, Annals of medicine.

Carbonic anhydrase II and H+-ATPase in osteoclasts of four osteopetrotic mutations in the rat

H. Väänänen, Jr, K. Sundquist, 1999, Histochemistry and Cell Biology.

Conditioned medium from osteocytes stimulates the proliferation of bone marrow mesenchymal stem cells and their differentiation into osteoblasts.

T. Hentunen, T. Heino, H. Väänänen, 2004, Experimental cell research.

Regulation of osteoblast differentiation: a novel function for fibroblast growth factor 8.

P. Härkönen, T. Hentunen, E. Valve, 2006, Endocrinology.

Calcium incorporation in matrix vesicles isolated from chicken epiphyseal cartilage

H. Väänänen, 2006, Calcified Tissue International.

Release of Intact and Fragmented Osteocalcin Molecules from Bone Matrix during Bone Resorption in Vitro*

K. Pettersson, T. Hentunen, H. Väänänen, 2004, Journal of Biological Chemistry.

The effect of training on the recovery from immobilization-induced bone loss in rats.

J. Tuukkanen, H. Väänänen, Z. Peng, 1992, Acta physiologica Scandinavica.

Estrogen Reduces the Depth of Resorption Pits by Disturbing the Organic Bone Matrix Degradation Activity of Mature Osteoclasts.

J. Risteli, P. Lehenkari, V. Parikka, 2001, Endocrinology.

Effect of Postmenopausal Estrogen Treatment on Some Diagnostic Salivary Variables

J. Heikkinen, H. Väänänen, M. Larmas, 1993, Annals of the New York Academy of Sciences.

Decreased bone resorption, osteoclast differentiation, and expression of vacuolar H+-ATPase in antisense DNA-treated mouse metacarpal and calvaria cultures ex vivo.

H. Väänänen, T. Laitala-Leinonen, 1999, Antisense & nucleic acid drug development.

RNA Interference Tolerates 2′‐Fluoro Modifications at the Argonaute2 Cleavage Site

Pirkko Muhonen, A. Azhayev, H. Väänänen, 2007, Chemistry & biodiversity.

Osteoclast lineage and function.

Tiina Laitala-Leinonen, H. Väänänen, H Kalervo Väänänen, 2008, Archives of biochemistry and biophysics.

Urinary osteocalcin and serum pro‐C‐type natriuretic peptide predict linear catch‐up growth in infants

J. Rehfeld, L. Dunkel, J. Goetze, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Monocyte–Macrophage System as a Target for Estrogen and Selective Estrogen Receptor Modulators

P. Härkönen, PIRKKO L. HÄRKÖNEN, H. KALERVO VÄÄNÄNEN, 2006, Annals of the New York Academy of Sciences.

Membrane-bound carbonic anhydrases in osteoclasts.

C. Supuran, S. Pastoreková, S. Parkkila, 2007, Bone.

Isolated primary osteocytes express functional gap junctions in vitro

K. Metsikkö, T. Hentunen, H. Väänänen, 2006, Cell and Tissue Research.

High active isoenzyme of carbonic anhydrase in rat calvaria osteoclasts

H. Väänänen, E. Parvinen, 1983, Histochemistry.

Alendronate-induced disruption of actin cytoskeleton and inhibition of migration/invasion are associated with cofilin downregulation in PC-3 prostate cancer cells

S. Virtanen, P. Härkönen, E. Löyttyniemi, 2018, Oncotarget.

Carbonic anhydrase in the type I skeletal muscle fibers of the rat. An immunohistochemical study.

H. Väänänen, T. Kumpulainen, L. Korhonen, 1982, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Effect of immobilization on carbonic anhydrase III and myoglobin content in human leg muscle.

T. Takala, J. Puranen, H. Väänänen, 1991, Acta physiologica Scandinavica.

Liberation of muscle carbonic anhydrase into serum during extensive exercise.

T. Takala, M. Leppilampi, H. Väänänen, 1986, Journal of applied physiology.

Matrix vesicle calcification in rat epiphyseal growth plate cartilage prepared anhydrously for electron microscopy.

H. Anderson, D. Morris, H. Väänänen, 1983, Metabolic bone disease & related research.

Androgen regulation of carbonic anhydrase II, a major soluble protein in rat lateral prostate tissue.

P. Härkönen, H. Väänänen, 1988, Biology of reproduction.

Immunoelectron microscopic localization of carbonic anhydrase III in rat skeletal muscle

T. Takala, D. Morris, H. Väänänen, 2004, Histochemistry.

Muscle-specific carbonic anhydrase III is a more sensitive marker of muscle damage than creatine kinase in neuromuscular disorders.

T. Takala, U. Tolonen, H. Väänänen, 1988, Archives of neurology.

Carbonic anhydrase III: a new histochemical marker for myoepithelial cells.

H. Väänänen, H. Autio–Harmainen, 1987, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Immunohistochemical demonstration of extracellular carbonic anhydrase in epiphyseal growth cartilage

H. Väänänen, T. Kumpulainen, 2006, Calcified Tissue International.

Immunohistochemical localization of carbonic anhydrase isoenzymes I and II in human bone, cartilage and giant cell tumor

H. Väänänen, 2004, Histochemistry.

Possible Role of Direct Rac1-Rab7 Interaction in Ruffled Border Formation of Osteoclasts*

Yi Sun, H. Väänänen, O. Ettala, 2005, Journal of Biological Chemistry.

Effect of clodronate treatment on established bone loss in ovariectomized rats.

H. Väänänen, Z. Peng, K. Kippo, 1998, Bone.

Clodronate Prevents Osteopenia and Loss of Trabecular Connectivity in Estrogen‐Deficient Rats

J. Tuukkanen, H. Väänänen, K. Kippo, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The Effect of Orally Administered Clodronate on Bone Mineral Density and Bone Geometry in Ovariectomized Rats Materials and Methods

H. Väänänen, Z. Peng, K. Kippo, 2022 .

Osteoclast Function: Biology and Mechanisms

H. Väänänen, Haibo Zhao, 2008 .

FGF‐8 is involved in bone metastasis of prostate cancer

A. Bjartell, P. Härkönen, E. Valve, 2008, International journal of cancer.

Degradation of hydroxyapatite in vivo and in vitro requires osteoclastic sodium-bicarbonate co-transporter NBCn1.

T. Kwon, H. Väänänen, T. Laitala-Leinonen, 2010, Matrix biology : journal of the International Society for Matrix Biology.

Biochemical Markers of Bone Metabolism and Prediction of Fracture in Elderly Women

Anders Isaksson, Kim Pettersson, P. Gerdhem, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Osteoclasts and a small population of peripheral blood cells share common surface antigens

J. Tuukkanen, T. Hentunen, H. Väänänen, 1990, Calcified Tissue International.

The osteoclast clear zone is a specialized cell-extracellular matrix adhesion structure.

M Horton, M. Horton, H. Väänänen, 1995, Journal of cell science.

Vitronectin receptor has a role in bone resorption but does not mediate tight sealing zone attachment of osteoclasts to the bone surface

M. Horton, M. Helfrich, H. Väänänen, 1991, The Journal of cell biology.

Inhibition of bone resorption in vitro by a peptide containing the cadherin cell adhesion recognition sequence HAV is due to prevention of sealing zone formation.

H. Väänänen, J. Ilvesaro, P. Lakkakorpi, 1998, Experimental cell research.

Osteocyte-derived HB-GAM (pleiotrophin) is associated with bone formation and mechanical loading.

H. Rauvala, K. Kurata, Y. Matsusue, 2009, Bone.

HRT and exercise: effects on bone density, muscle strength and lipid metabolism. A placebo controlled 2-year prospective trial on two estrogen-progestin regimens in healthy postmenopausal women.

J. Heikkinen, H. Väänänen, E. Kyllönen, 1997, Maturitas.

Overexpression of vascular endothelial growth factor C increases growth and alters the metastatic pattern of orthotopic PC-3 prostate tumors

P. Härkönen, H. Väänänen, J. Tuomela, 2009, BMC Cancer.

Serum TRACP 5 b and ICTP as Markers of Bone Metastases in Breast Cancer

H. Helenius, E. Salminen, H. Väänänen, 2008 .

Bone Marrow Cell Differentiation Induced by Mechanically Damaged Osteocytes in 3D Gel‐Embedded Culture

Kosaku Kurata, Hidehiko Higaki, H. Higaki, 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Bone morphogenetic protein 3b expressing reindeer antler.

J. Tuukkanen, J. Ryhänen, H. Väänänen, 2002, Journal of biomedical materials research.

Bone turnover markers and prediction of fracture: A prospective follow‐up study of 1040 elderly women for a mean of 9 years

P. Gerdhem, K. Obrant, H. Väänänen, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Serial assessment of serum bone metabolism markers identifies women with the highest rate of bone loss and osteoporosis risk.

P. Gerdhem, K. Obrant, H. Väänänen, 2008, The Journal of clinical endocrinology and metabolism.

Urinary osteocalcin is a useful marker for monitoring the effect of alendronate therapy.

P. Kannus, A. Heinonen, K. Pettersson, 2005, Clinical chemistry.

Development and evaluation of three immunofluorometric assays that measure different forms of osteocalcin in serum.

M. Karp, Pirjo Laaksonen, S. Käkönen, 2000, Clinical chemistry.

Skeletal Changes in Transgenic Male Mice Expressing Human Cytochrome P450 Aromatase

M. Poutanen, S. Mäkelä, Xiangdong Li, 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The Effects of Tamoxifen and Toremifene on Bone Cells Involve Changes in Plasma Membrane Ion Conductance

M. Weckström, P. Lehenkari, V. Parikka, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Serum TRACP 5b and ICTP as markers of bone metastases in breast cancer.

H. Helenius, E. Salminen, H. Väänänen, 2006, Anticancer research.

Clinical performance of six different serum tartrate-resistant acid phosphatase assays for monitoring alendronate treatment.

Sulin Cheng, A. Nenonen, K. Uusi-Rasi, 2008, Clinical laboratory.

Immunocytochemical localization of mitochondrial carbonic anhydrase in rat tissues.

S. Dodgson, H. Väänänen, N. Carter, 1991, Journal of Histochemistry and Cytochemistry.

FGF‐8b induces growth and rich vascularization in an orthotopic PC‐3 model of prostate cancer

P. Härkönen, K. Pettersson, H. Väänänen, 2009, Journal of cellular biochemistry.

Intracellular membrane trafficking in bone resorbing osteoclasts

H. Väänänen, M. Mulari, J. Vääräniemi, 2003, Microscopy research and technique.

Comparative effects of estrogen and antiestrogens on differentiation of osteoblasts in mouse bone marrow culture

P. Härkönen, H. Väänänen, Q. Qu, 1999, Journal of cellular biochemistry.

Bisphosphonates clodronate and etidronate in the prevention of ovariectomy‐induced osteopenia in growing rats

V. Lepola, P. Jalovaara, H. Väänänen, 1996, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Clodronate Prevents Bone Loss in Aged Ovariectomized Rats

H. Väänänen, Z. Peng, I. Pasanen, 1997, Calcified Tissue International.

Characterization of Circulating Human Osteoclast Progenitors: Development of In Vitro Resorption Assay

T. Hentunen, H. Väänänen, M. Husheem, 2005, Calcified Tissue International.

Mechanism of bone turnover.

H. Väänänen, 1993, Annals of medicine.

Rab13 Is Upregulated During Osteoclast Differentiation and Associates with Small Vesicles Revealing Polarized Distribution in Resorbing Cells

P. Härkönen, H. Väänänen, M. Mulari, 2012, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Osteocyte-derived HB-GAM (pleiotrophin) is associated with bone formation and mechanical loading.

H. Rauvala, Y. Matsusue, T. Heino, 2009, Bone.

Matrix vesicles in chicken epiphyseal cartilage. Separation from lysosomes and the distribution of inorganic pyrophosphatase activity

H. Väänänen, L. Korhonen, 1979, Calcified Tissue International.

Osteocytes inhibit osteoclastic bone resorption through transforming growth factor-β: Enhancement by estrogen*This paper has been presented in part as an abstract at the 27th European Symposium on Calcified Tissues, Tampere, Finland, 6–10 May 2000.

T. Hentunen, T. Heino, H. Väänänen, 2002 .

The Effect of Oral Glucose Tolerance Test on Serum Osteocalcin and Bone Turnover Markers in Young Adults

O. Mäkitie, E. Kajantie, H. Väänänen, 2012, Calcified Tissue International.