C. Tom

Human Huntington's Disease iPSC-Derived Cortical Neurons Display Altered Transcriptomics, Morphology, and Maturation.

V. Mattis, Yizhou Wang, Jie Tang, 2018, Cell reports.

Bioenergetic deficits in Huntington’s disease iPSC-derived neural cells and rescue with glycolytic metabolites

Amanda J. Kedaigle, E. Fraenkel, M. MacDonald, 2019, Human molecular genetics.

Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice

Amanda J. Kedaigle, E. Fraenkel, M. MacDonald, 2017, Nature Neuroscience.

Neonatal immune-tolerance in mice does not prevent xenograft rejection

J. Kordower, H. Dodiya, C. Svendsen, 2014, Experimental Neurology.

Inducible Expression of GDNF in Transplanted iPSC-Derived Neural Progenitor Cells

Joshua J. Breunig, D. Saxon, C. Svendsen, 2018, Stem cell reports.

HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity.

M. Hayden, C. Ross, C. Svendsen, 2015, Human molecular genetics.

Optimization of trans-Splicing for Huntington's Disease RNA Therapy

C. Lorson, V. Mattis, H. Rindt, 2017, Front. Neurosci..

The Interaction of Aging and Cellular Stress Contributes to Pathogenesis in Mouse and Human Huntington Disease Neurons

M. Hayden, V. Mattis, N. Caron, 2020, Frontiers in Aging Neuroscience.

The interaction of aging and oxidative stress contributes to pathogenesis in mouse and human Huntington disease neurons

M. Hayden, V. Mattis, N. Caron, 2019, bioRxiv.

Huntington’s Disease Patient-Derived Astrocytes Display Electrophysiological Impairments and Reduced Neuronal Support

C. Svendsen, V. Mattis, N. Allen, 2019, Front. Neurosci..

Survival of iPSC-derived grafts within the striatum of immunodeficient mice: Importance of developmental stage of both transplant and host recipient

V. Mattis, Elana A. Meer, C. Bresee, 2017, Experimental Neurology.

ERα signaling regulates MMP3 expression to induce FasL cleavage and osteoclast apoptosis

C. Tom, M. Mayorga, Gustavo A. Miranda-Carboni, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Characterization of Neurodevelopmental Abnormalities in iPSC-Derived Striatal Cultures from Patients with Huntington’s Disease

V. Mattis, C. Tom, Pranav P Mathkar, 2019, Journal of Huntington's disease.