Mark Wade

Hdmx Modulates the Outcome of P53 Activation in Human Tumor Cells*

Mengjia Tang, G. Wahl, J. Stommel, 2006, Journal of Biological Chemistry.

A stapled p53 helix overcomes HDMX-mediated suppression of p53.

Tina N. Davis, Andrew L Kung, G. Wahl, 2010, Cancer cell.

MDM2, MDMX and p53 in oncogenesis and cancer therapy

G. Wahl, M. Wade, Yao-Cheng Li, 2013, Nature Reviews Cancer.

High-Throughput Silencing Using the CRISPR-Cas9 System

M. Wade, Mark Wade, 2015, Journal of biomolecular screening.

Targeting Mdm2 and Mdmx in Cancer Therapy: Better Living through Medicinal Chemistry?

G. Wahl, M. Wade, Mark Wade, 2009, Molecular Cancer Research.

Multiplex detection of protein-protein interactions using a next generation luciferase reporter.

M. Mattioli, M. Wade, Yao-Cheng Li, 2016, Biochimica et biophysica acta.

c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability.

G. Wahl, S. Kern, G. Hampton, 2002, Molecular cell.

Quantitative analyses reveal the importance of regulated Hdmx degradation for P53 activation

G. Wahl, M. Wade, Yunyuan V. Wang, 2007, Proceedings of the National Academy of Sciences.