Zhonghua Pei

发表

Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors.

Gang Liu, Hongyu Zhao, Cristina M Rondinone, 2004, Bioorganic & medicinal chemistry letters.

A Highly Efficient Approach to a Selective and Cell Active PTP1B inhibitors

Gang Liu, Hongyu Zhao, Charles W. Hutchins, 2003 .

Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors.

Gang Liu, C. Abad-Zapatero, Xiaofen Li, 2003, Bioorganic & medicinal chemistry letters.

Selective protein tyrosine phosphatase 1B inhibitors: targeting the second phosphotyrosine binding site with non-carboxylic acid-containing ligands.

Gang Liu, Cristina M Rondinone, P. Hajduk, 2003, Journal of medicinal chemistry.

Inhibition of protein tyrosine phosphatase 1B as a potential treatment of diabetes and obesity.

Gang Liu, Gang Liu, T. Lubben, 2004, Current pharmaceutical design.

Discovery of Potent Antagonists of Leukocyte Function‐Associated Antigen‐1/Intercellular Adhesion Molecule‐1 Interaction. Part 3. Amide (C‐Ring) Structure—Activity Relationship and Improvement of Overall Properties of Arylthio Cinnamides.

Zhonghua Pei, 2001 .

Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B.

Gang Liu, P. Hajduk, S. Fesik, 2003, Journal of medicinal chemistry.

Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Compound 12 Using a Linked-Fragment Strategy

Gang Liu, Charles W. Hutchins, Stephen W. Fesik, 2003 .

Discovery of a potent, selective protein tyrosine phosphatase 1B inhibitor using a linked-fragment strategy.

Gang Liu, P. Hajduk, S. Fesik, 2003, Journal of the American Chemical Society.

Potent, selective inhibitors of protein tyrosine phosphatase 1B.

Gang Liu, P. Hajduk, C. Abad-Zapatero, 2003, Bioorganic & medicinal chemistry letters.

Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors.

Hing L Sham, Zhonghua Pei, Thomas H Lubben, 2006, Journal of medicinal chemistry.

Crystal structures of DPP-IV (CD26) from rat kidney exhibit flexible accommodation of peptidase-selective inhibitors.

Vincent S Stoll, K. Longenecker, V. Stoll, 2006, Biochemistry.

Fragment screening and assembly: a highly efficient approach to a selective and cell active protein tyrosine phosphatase 1B inhibitor.

Gang Liu, Hongyu Zhao, Cristina M Rondinone, 2003, Journal of medicinal chemistry.