J. Ardell

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Autonomic regulation therapy via left or right cervical vagus nerve stimulation in patients with chronic heart failure: results of the ANTHEM-HF trial.

Imad Libbus, Kamal Sharma, B. KenKnight, 2014, Journal of cardiac failure.

Electroceutical Targeting of the Autonomic Nervous System.

L. Fisher, J. Ardell, Charles C Horn, 2019, Physiology.

Left vagal stimulation induces dynorphin release and suppresses substance P release from the rat thoracic spinal cord during cardiac ischemia.

J. Ardell, Fang Hua, C.A. Williams, 2004, American journal of physiology. Regulatory, integrative and comparative physiology.

Spinal cord activation differentially modulates ischaemic electrical responses to different stressors in canine ventricles

R. Cardinal, M. Vermeulen, B. Linderoth, 2004, Autonomic Neuroscience.

Brain-Heart Afferent-Efferent Traffic

J. Ardell, V. Dusi, 2020 .

Parasympathetic control of the heart. II. A novel interganglionic intrinsic cardiac circuit mediates neural control of heart rate.

J. Ardell, A. Gray, T. A. Johnson, 2004, Journal of applied physiology.

Functional interdependence of discrete vagal projections to SA and AV nodes.

W. C. Randall, J. Ardell, M. O'Toole, 1986, The American journal of physiology.

Parasympathetic ganglia innervating the canine atrioventricular nodal region.

W. C. Randall, J. Ardell, D. Calderwood, 1986, Journal of the autonomic nervous system.

Vagal postganglionic innervation of the canine sinoatrial node.

W. C. Randall, J. Ardell, R. Wurster, 1987, Journal of the autonomic nervous system.

Gross and microscopic anatomy of the canine intrinsic cardiac nervous system

D. Hopkins, J. Ardell, J. Armour, 1994, The Anatomical record.

Therapeutic responsiveness to vagus nerve stimulation in patients receiving beta-blockade for heart failure with reduced ejection fraction

L. DiCarlo, I. Anand, R. Premchand, 2021, International journal of cardiology. Heart & vasculature.

Cardiac innervation and sudden cardiac death.

Y. Aizawa, K. Fukuda, K. Shivkumar, 2015, Circulation research.

Alpha-adrenoceptor blockade modifies neurally induced atrial arrhythmias.

R. Cardinal, A. Vinet, T. Kus, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Stochastic behavior of atrial and ventricular intrinsic cardiac neurons.

G. Kember, J. Ardell, J. Armour, 2006, Journal of applied physiology.

Ablation of posterior atrial ganglionated plexus potentiates sympathetic tachycardia to behavioral stress.

W. C. Randall, D. Randall, J. Ardell, 1998, The American journal of physiology.

Ablation of posterior atrial ganglionated plexus potentiates sympathetic tachycardia to behavioral stress.

W. C. Randall, D. Randall, J. Ardell, 1998, American journal of physiology. Regulatory, integrative and comparative physiology.

Remodeling of the guinea pig intrinsic cardiac plexus with chronic pressure overload.

J. Ardell, J. Hardwick, Caitlin N. Baran, 2009, American journal of physiology. Regulatory, integrative and comparative physiology.

Chronic myocardial infarction induces phenotypic and functional remodeling in the guinea pig cardiac plexus.

J. Ardell, J. Hardwick, E. M. Southerland, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

guinea pig intrinsic cardiac neurone excitability Neurally released pituitary adenylate cyclase-activating polypeptide enhances

J. D. Tompkins, J. Ardell, D. Hoover, 2008 .

Neurally released pituitary adenylate cyclase‐activating polypeptide enhances guinea pig intrinsic cardiac neurone excitability

J. D. Tompkins, J. Ardell, D. Hoover, 2007, The Journal of physiology.

Cardiac responses to exercise in the dog before and after destruction of the sinoatrial node

W. C. Randall, J. Ardell, D. Calderwood, 2006, European Journal of Applied Physiology and Occupational Physiology.

Impact of Autonomic Regulation Therapy in Patients with Heart Failure: ANTHEM-HFrEF Pivotal Study Design.

J. Butler, L. DiCarlo, H. Klein, 2019, Circulation. Heart failure.

Fast in vivo detection of myocardial norepinephrine levels in the beating porcine heart

K. Shivkumar, M. Vaseghi, J. Ardell, 2020, American journal of physiology. Heart and circulatory physiology.

&bgr;1-Adrenergic Receptor Blockade Attenuates Angiotensin II–Mediated Catecholamine Release Into the Cardiac Interstitium in Mitral Regurgitation

L. Dell’Italia, A. R. Dillon, Chih-Chang Wei, 2003, Circulation.

Advances in Our Clinical Understanding of Autonomic Regulation Therapy Using Vagal Nerve Stimulation in Patients Living With Heart Failure

J. Butler, J. Massaro, M. Cowie, 2022, Frontiers in Physiology.

Long-term follow-up of patients with heart failure and reduced ejection receiving autonomic regulation therapy in the ANTHEM-HF pilot study.

B. KenKnight, L. DiCarlo, S. Mittal, 2020, International journal of cardiology.

Phosphodiesterase 2A as a therapeutic target to restore cardiac neurotransmission during sympathetic hyperactivity.

M. Zaccolo, D. Paterson, K. Shivkumar, 2018, JCI insight.

Extended Follow-Up of Patients With Heart Failure Receiving Autonomic Regulation Therapy in the ANTHEM-HF Study.

B. KenKnight, L. DiCarlo, T. Rector, 2016, Journal of cardiac failure.

Short-Acting β-Adrenergic Antagonist Esmolol Given at Reperfusion Improves Survival After Prolonged Ventricular Fibrillation

R. Ideker, G. Walcott, William M. Smith, 2004, Circulation.

Cardiac sympathectomy and spinal cord stimulation attenuate reflex-mediated norepinephrine release during ischemia preventing ventricular fibrillation.

K. Shivkumar, R. Foreman, J. Ardell, 2019, JCI insight.

Myocardial infarction induces structural and functional remodelling of the intrinsic cardiac nervous system

Pradeep S Rajendran, K. Shivkumar, O. Ajijola, 2016, The Journal of physiology.

Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies

Charless C. Fowlkes, J. D. Tompkins, Rosemary C Challis, 2018, Nature Communications.

Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies

Charless C. Fowlkes, J. D. Tompkins, Rosemary C Challis, 2018, bioRxiv.

The effects of albumin administration on microvascular permeability at the site of burn injury.

A. Taylor, J. Ardell, J. Ferrara, 1994, The Journal of trauma.

Measure of synchrony in the activity of intrinsic cardiac neurons

V. Jacquemet, J. Ardell, J. Armour, 2014, Physiological measurement.

Stellate ganglion stimulation causes spatiotemporal changes of ventricular repolarization in pig.

T. Opthof, R. Coronel, M. Janse, 2020, Heart rhythm.

Autonomic regulation therapy to enhance myocardial function in heart failure patients: the ANTHEM‐HFpEF study

B. KenKnight, L. DiCarlo, S. Mittal, 2017, ESC heart failure.

Structural and function organization of intrathoracic extracardiac autonomic projections to the porcine heart: implications for targeted neuromodulation therapy.

K. Shivkumar, M. Dacey, J. Ardell, 2022, Heart rhythm.

Central vs. peripheral neuraxial sympathetic control of porcine ventricular electrophysiology.

Pradeep S Rajendran, Wei Zhou, A. Mahajan, 2016, American journal of physiology. Regulatory, integrative and comparative physiology.

Selective Modulation of Heart and Respiration by Optical Control of Vagus Nerve Axons Innervating the Heart

Gregory L. Futia, Arjun K. Fontaine, Pradeep S Rajendran, 2020, bioRxiv.

Vagus nerve stimulation mitigates intrinsic cardiac neuronal remodeling and cardiac hypertrophy induced by chronic pressure overload in guinea pig.

B. KenKnight, J. Ardell, J. Armour, 2016, American journal of physiology. Heart and circulatory physiology.

Vagal stimulation targets select populations of intrinsic cardiac neurons to control neurally induced atrial fibrillation.

V. Jacquemet, K. Shivkumar, A. Vinet, 2016, American journal of physiology. Heart and circulatory physiology.

Vagus nerve stimulation mitigates intrinsic cardiac neuronal and adverse myocyte remodeling postmyocardial infarction.

B. KenKnight, J. Ardell, J. Armour, 2015, American journal of physiology. Heart and circulatory physiology.

Differential cardiac responses induced by nicotine sensitive canine atrial and ventricular neurones.

D. Hopkins, J. Ardell, J. Armour, 1993, Cardiovascular research.

Autonomic interactions for control of atrial rate are maintained after SA nodal parasympathectomy.

J. Ardell, D. Schmacht, A. S. McGuirt, 1997, The American journal of physiology.

Spatially divergent cardiac responses to nicotinic stimulation of ganglionated plexus neurons in the canine heart

R. Cardinal, P. Pagé, M. Vermeulen, 2009, Autonomic Neuroscience.

Remodeling of intrinsic cardiac neurons: effects of β-adrenergic receptor blockade in guinea pig models of chronic heart disease.

J. Ardell, A. Girasole, J. Hardwick, 2012, American journal of physiology. Regulatory, integrative and comparative physiology.

Abstract 15586: Optimum Heart Rate Response to Autonomic Regulation Therapy is Frequency Dependent

B. KenKnight, J. Ardell, B. Amurthur, 2013 .

Rapid measurement of cardiac neuropeptide dynamics by capacitive immunoprobe in the porcine heart.

K. Shivkumar, M. Dacey, J. Ardell, 2020, American journal of physiology. Heart and circulatory physiology.

Activated cranial cervical cord neurons affect left ventricular infarct size and the potential for sudden cardiac death

R. Foreman, J. Ardell, C.A. Williams, 2012, Autonomic Neuroscience.

Spinal cord neural network interactions: implications for sympathetic control of the porcine heart.

M. Sunshine, A. Mahajan, J. Ardell, 2020, American journal of physiology. Heart and circulatory physiology.

Thoracic spinal cord neuromodulation obtunds dorsal root ganglion afferent neuronal transduction of the ischemic ventricle.

J. Ardell, J. Armour, Sarah M Ardell, 2019, American journal of physiology. Heart and circulatory physiology.

Foundational concepts for cardiac neuromodulation

K. Shivkumar, J. Ardell, 2018 .

Thoracic spinal cord and cervical vagosympathetic neuromodulation obtund nodose sensory transduction of myocardial ischemia

J. Ardell, J. Armour, D. Hoover, 2017, Autonomic Neuroscience.

Bioelectronic neuromodulation of the paravertebral cardiac efferent sympathetic outflow and its effect on ventricular electrical indices.

Pradeep S Rajendran, K. Shivkumar, J. Ardell, 2017, Heart rhythm.

Targeted stellate decentralization: Implications for sympathetic control of ventricular electrophysiology.

K. Shivkumar, K. Yamakawa, J. Ardell, 2016, Heart rhythm.

Heart failure: Mechanisms of spinal cord neuromodulation for heart disease

J. Ardell, 2016, Nature Reviews Cardiology.

Angiotensin receptors alter myocardial infarction-induced remodeling of the guinea pig cardiac plexus.

J. Ardell, J. Hardwick, E. M. Southerland, 2015, American journal of physiology. Regulatory, integrative and comparative physiology.

Network interactions within the canine intrinsic cardiac nervous system: implications for reflex control of regional cardiac function

V. Jacquemet, A. Vinet, J. Ardell, 2013, The Journal of physiology.

Effects of chronic cardiac decentralization on functional properties of canine intracardiac neurons in vitro.

J. Ardell, J. Armour, J. Leger, 2001, American journal of physiology. Regulatory, integrative and comparative physiology.

Innervation and Neuronal Control of the Mammalian Sinoatrial Node a Comprehensive Atlas

J. D. Tompkins, Pradeep S Rajendran, I. Efimov, 2021, Circulation research.

Intrinsic cardiac nervous system in tachycardia induced heart failure.

R. Cardinal, L. Dell’Italia, R. Arora, 2003, American journal of physiology. Regulatory, integrative and comparative physiology.

Calcitonin Gene-Related Peptide In Vivo Positive Inotropy Is Attributable to Regional Sympatho-Stimulation and Is Blunted in Congestive Heart Failure

D. Kass, Robert H. Helm, N. Paolocci, 2005, Circulation research.

Sympatho-Stimulation and Is Blunted in Congestive Heart Failure Calcitonin Gene-Related Peptide In Vivo Positive Inotropy Is Attributable to Regional

D. Kass, Robert H. Helm, N. Paolocci, 2005 .

Dynamicremodeling of theguineapigintrinsiccardiacplexusinducedby chronic myocardial infarction

J. Ardell, E. Beaumont, J. Hardwick, 2014 .

Dynamic remodeling of the guinea pig intrinsic cardiac plexus induced by chronic myocardial infarction

J. Ardell, E. Beaumont, J. Hardwick, 2014, Autonomic Neuroscience.

Beta1-adrenoceptor blockade mitigates excessive norepinephrine release into cardiac interstitium in mitral regurgitation in dog.

R. Cardinal, L. Dell’Italia, I. Aban, 2006, American journal of physiology. Heart and circulatory physiology.

Sympathetic modulation of electrical activation in normal and infarcted myocardium: implications for arrhythmogenesis.

D. Ennis, M. Fishbein, R. Lux, 2017, American journal of physiology. Heart and circulatory physiology.

Differential autonomic control of SAN and AVN regions of the canine heart: structure and function.

W. C. Randall, J. Ardell, R. Wurster, 1988, Progress in clinical and biological research.

Activity of in vivo atrial and ventricular neurons in chronically decentralized canine hearts.

D. Hopkins, J. Ardell, J. Armour, 1991, The American journal of physiology.

Endogenous myocardial norepinephrine is not essential for ischemic preconditioning in rabbit heart.

J. Downey, M. Cohen, J. Ardell, 1996, The American journal of physiology.

Cardiac vanilloid receptor-1 afferent depletion enhances stellate ganglion neuronal activity and efferent sympathetic response to cardiac stress.

Pradeep S Rajendran, K. Shivkumar, O. Ajijola, 2018, American journal of physiology. Heart and circulatory physiology.

Sympathetic neural recording-It is all in the details.

K. Shivkumar, J. Ardell, 2017, Heart rhythm.

Remodeling of stellate ganglion neurons after spatially targeted myocardial infarction: Neuropeptide and morphologic changes.

K. Shivkumar, O. Ajijola, D. Yagishita, 2015, Heart rhythm.

Effects of transient coronary artery occlusion on canine intrinsic cardiac neuronal activity

B. Hanna, J. Ardell, J. Armour, 1993, Integrative physiological and behavioral science : the official journal of the Pavlovian Society.

Vagus nerve stimulation using a miniaturized wirelessly powered stimulator in pigs

A. Babakhani, H. Lyu, A. Bari, 2022, Scientific Reports.

Neurochemical diversity of afferent neurons that transduce sensory signals from dog ventricular myocardium

J. Ardell, J. Armour, D. Hoover, 2008, Autonomic Neuroscience.

Neurohumoral Control of Cardiac Function

J. Ardell, 2001 .

ENCORE: Extension of the ANTHEM-HF Study Evaluating Autonomic Regulation Therapy in Reduced Ejection Fraction Heart Failure

B. KenKnight, L. DiCarlo, T. Rector, 2015 .

Effects of left atrial and airway pressures on airway blood flow.

S. Barman, A. Taylor, J. Ardell, 1993, Respiration physiology.

Altered pulmonary microvascular reactivity to norepinephrine in canine pacing-induced heart failure.

J. Ardell, M. Townsley, W. Johnson, 1994, Circulation research.

Angiotensin II modulates catecholamine release into interstitial fluid of canine myocardium in vivo.

L. Dell’Italia, J. Ardell, J. Armour, 2001, American journal of physiology. Heart and circulatory physiology.

LONG-TERM FOLLOW-UP OF REDUCED EJECTION FRACTION HEART FAILURE PATIENTS RECEIVING AUTONOMIC REGULATION THERAPY IN THE ANTHEM-HF PILOT STUDY

B. KenKnight, L. DiCarlo, S. Mittal, 2019, Journal of the American College of Cardiology.

Effect of superoxide dismutase on acute reperfusion injury of the rabbit brain

A. Taylor, J. Ardell, E. Taşdemiroğlu, 2005, Acta Neurochirurgica.

The cardiac neuronal hierarchy and susceptibility to arrhythmias.

J. Ardell, 2011, Heart rhythm.

Long-term modulation of the intrinsic cardiac nervous system by spinal cord neurons in normal and ischaemic hearts

R. Arora, B. Linderoth, R. Foreman, 2002, Autonomic Neuroscience.

Pathological effects of chronic myocardial infarction on peripheral neurons mediating cardiac neurotransmission

K. Shivkumar, E. Aliotta, O. Ajijola, 2016, Autonomic Neuroscience.

Bioelectronic block of paravertebral sympathetic nerves mitigates post-myocardial infarction ventricular arrhythmias.

Pradeep S Rajendran, K. Shivkumar, J. Ardell, 2017, Heart rhythm.

Abstract 19667: Vagus Nerve Stimulation Normalizes Autonomic Neural Processing and Reduces Cardiac Hypertrophy in a Canine Model of Preserved Ejection Fraction Heart Failure

Pradeep S Rajendran, B. KenKnight, S. Girouard, 2016 .

CHRONIC AUTONOMIC REGULATION THERAPY MITIGATES ADVERSE REMODELING INDUCED BY PRESSURE OVERLOAD IN THE GUINEA PIG HEART

B. KenKnight, J. Ardell, E. Beaumont, 2014 .

Selective ganglionic blockade of vagal inputs to sinoatrial and/or atrioventricular regions.

W. C. Randall, J. Ardell, R. Wurster, 1987, The Journal of pharmacology and experimental therapeutics.

Premature ventricular contractions activate vagal afferents and alter autonomic tone: implications for premature ventricular contraction-induced cardiomyopathy.

M. Vaseghi, J. Ardell, J. Armour, 2019, American journal of physiology. Heart and circulatory physiology.

Cervical Segments Inputs in Monkeys: Neuronal Processing in High Spinal Inhibitory Effects of Cardiopulmonary Afferent

A. Mohr, A. Farmer, Q. Aziz, 2015 .

Remodeling of Stellate Ganglion Neurons following Spatially Targeted Myocardial Infarction: Neuropeptide and Morphologic Changes

K. Shivkumar, O. Ajijola, D. Yagishita, 2015 .

Effect of phorbol myristate acetate-induced lung injury on airway blood flow.

S. Barman, A. Taylor, J. Ardell, 1995, Respiration physiology.

Effects of hypertonic saline and dextran 70 resuscitation on microvascular permeability after burn.

A. Taylor, J. Ardell, J. Ferrara, 1992, The American journal of physiology.

Canine intrinsic cardiac neurons involved in cardiac regulation possess NK1, NK2, and NK3 receptors.

J. Ardell, J. Armour, D. Hoover, 1998, American journal of physiology. Regulatory, integrative and comparative physiology.

Vagally-mediated heart block after myocardial infarction associated with plasticity of epicardial neurons controlling the atrioventricular node

J. D. Tompkins, K. Shivkumar, J. Ardell, 2022, Frontiers in Synaptic Neuroscience.

Renal Dysfunction in Heart Failure

J. Ardell, J. Hadaya, 2022, JACC. Basic to translational science.

Effects of antioxidants on the blood-brain barrier and postischemic hyperemia

A. Taylor, J. Ardell, E. Taşdemiroğlu, 2005, Acta Neurochirurgica.

Angiotensin II potentiates adrenergic and muscarinic modulation of guinea pig intracardiac neurons.

J. Ardell, A. Girasole, J. Hardwick, 2011, American journal of physiology. Regulatory, integrative and comparative physiology.

Redistribution of organ blood flow after hemorrhage and resuscitation in full-term piglets.

R. Powell, J. Ardell, J. Ferrara, 1994, Journal of pediatric surgery.

Neuromodulation therapy does not influence blood flow distribution or left-ventricular dynamics during acute myocardial ischemia

B. Linderoth, R. Foreman, J. Ardell, 2001, Autonomic Neuroscience.

Spinal opiate modulation of cardiovascular reflexes in the exercising dog

J. Ardell, R. Wurster, G. Pomeroy, 1986, Brain Research.

Indomethacin-induced blood flow distribution in premature and full-term piglets.

R. Powell, J. Ardell, J. Ferrara, 1993, Journal of pediatric surgery.

Translational neurocardiology: preclinical models and cardioneural integrative aspects

D. O'Leary, G. Billman, K. Sunagawa, 2016, The Journal of physiology.

Premature Ventricular Contraction Coupling Interval Variability Destabilizes Cardiac Neuronal and Electrophysiological Control: Insights From Simultaneous Cardioneural Mapping

Marmar Vaseghi, Kalyanam Shivkumar, Siamak Salavatian, 2017, Circulation. Arrhythmia and electrophysiology.

Myocardial ischemia induces the release of substance P from cardiac afferent neurons in rat thoracic spinal cord.

J. Ardell, Fang Hua, A. Reifsteck, 2004, American journal of physiology. Heart and circulatory physiology.

RNA Sequencing Reveals Novel Transcripts from Sympathetic Stellate Ganglia During Cardiac Sympathetic Hyperactivity

D. Paterson, K. Shivkumar, O. Ajijola, 2018, Scientific Reports.

Organ blood flow redistribution in response to hypoxemia in neonatal piglets.

R. Powell, J. Ardell, W. Roberts, 1998, Journal of investigative surgery : the official journal of the Academy of Surgical Research.

Increased arrhythmia susceptibility in type 2 diabetic mice related to dysregulation of ventricular sympathetic innervation.

C. Jungen, V. Nikolaev, J. Ardell, 2019, American journal of physiology. Heart and circulatory physiology.

Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies

Charless C. Fowlkes, G. Salama, V. Gradinaru, 2018, bioRxiv.

Sympathetic nerve discharge in chronic spinal cat.

G. L. Gebber, J. Ardell, S. Barman, 1982, American Journal of Physiology.

Interactions within the intrinsic cardiac nervous system contribute to chronotropic regulation.

D. Randall, J. Ardell, David R. Brown, 2003, American journal of physiology. Regulatory, integrative and comparative physiology.

Differential sympathetic regulation of automatic, conductile, and contractile tissue in dog heart.

W. C. Randall, J. Ardell, E. Taşdemiroğlu, 1988, The American journal of physiology.

Selective vagal innervation of the heart.

W. C. Randall, R D Wurster, W C Randall, 1986, Annals of clinical and laboratory science.

Nerve-sparing dissection as alternative to anesthesia of carotid sinus nerve in preparation for carotid endarterectomy.

S. Barman, R. Cantu, J. Ardell, 1989, Texas Heart Institute journal.

Development of a protocol to provide prolonged general anesthesia to pregnant sows.

J. Ardell, J. Ferrara, W. Roberts, 1994, Journal of investigative surgery : the official journal of the Academy of Surgical Research.

Selective vagal innervation of sinoatrial and atrioventricular nodes in canine heart.

W. C. Randall, J. Ardell, 1986, The American journal of physiology.

Brain-Heart Afferent-Efferent Traffic

J. Ardell, V. Dusi, Veronica Dusi, 2020, Brain and Heart Dynamics.

Neurocardiology: Structure-Based Function.

J. Ardell, J. Armour, 2016, Comprehensive Physiology.

Innervation and Neuronal Control of the Mammalian Sinoatrial Node: A Comprehensive Atlas

I. Efimov, J. Schwaber, R. Vadigepalli, 2020, bioRxiv.

A single cell transcriptomics map of paracrine networks in the intrinsic cardiac nervous system

J. Schwaber, R. Vadigepalli, K. Shivkumar, 2021, iScience.

A spatially-tracked single cell transcriptomics map of neuronal networks in the intrinsic cardiac nervous system

J. Schwaber, R. Vadigepalli, K. Shivkumar, 2020, bioRxiv.

Selective parasympathectomy of automatic and conductile tissues of the canine heart.

W. C. Randall, J. Ardell, 1985, The American journal of physiology.

Neural Control of Cardiac Function in Health and Disease

K. Shivkumar, O. Ajijola, M. Vaseghi, 2017 .

Autonomic Modulation for Cardiovascular Disease

J. Ardell, J. Hadaya, Joseph E. Hadaya, 2020, Frontiers in Physiology.

Functional interdependence of neurons in a single canine intrinsic cardiac ganglionated plexus

G Kember, G. Kember, J A Armour, 2000, The Journal of physiology.

The heart reinnervates after transplantation.

R. Cardinal, M. Wilkinson, R Cardinal, 2000, The Annals of thoracic surgery.

- Adrenoceptor blockade modifies neurally induced atrial arrhythmias

R. Cardinal, A. Vinet, T. Kus, 2008 .

Parasympathetic control of the heart. III. Neuropeptide Y-immunoreactive nerve terminals synapse on three populations of negative chronotropic vagal preganglionic neurons.

J. Lauenstein, J. Ardell, A. Gray, 2004, Journal of applied physiology.

Neuroscientific Therapies for Atrial Fibrillation.

K. Shivkumar, S. Stavrakis, J. Ardell, 2021, Cardiovascular research.

Vagal Neuromodulation for Atrial Arrhythmias.

K. Shivkumar, J. Ardell, 2017, JACC. Clinical electrophysiology.

Myocardial infarction reduces cardiac nociceptive neurotransmission through the vagal ganglia

Zulfiqar A. Lokhandwala, M. Vaseghi, J. Ardell, 2022, JCI insight.

Effects of graded thermal injury on microvascular permeability at the site of injury.

L. Flint, A. Taylor, J. Ardell, 1994, The Journal of surgical research.

Effects of pentafraction administration on microvascular permeability alterations induced by graded thermal injury.

L. Flint, A. Taylor, J. Ardell, 1994, Surgery.

Defining the neural fulcrum for chronic vagus nerve stimulation: implications for integrated cardiac control

B. KenKnight, J. Ardell, J. Armour, 2017, The Journal of physiology.

The Effect of Superoxide Dismutase on Rabbit Brain Reperfusion Injury

J. Ardell, E. Taşdemiroğlu, R. Chronister, 1989 .

Regional blood flow response to hypothermia in premature, newborn, and neonatal piglets.

R. Powell, J. Ardell, J. Ferrara, 1999, Journal of pediatric surgery.

Role of bradykinin in protection of ischemic preconditioning in rabbit hearts.

J. Downey, Yongge Liu, M. Cohen, 1995, Circulation research.

Calming the Nervous Heart: Autonomic Therapies in Heart Failure.

K. Shivkumar, J. Ardell, Peter Hanna, 2018, Cardiac failure review.

Differential selectivity of cardiac neurons in separate intrathoracic autonomic ganglia.

G. Kember, J. Ardell, J. Armour, 1998, American journal of physiology. Regulatory, integrative and comparative physiology.

Autonomic Regulation Therapy in Heart Failure

K. Shivkumar, J. Ardell, U. Buckley, 2015, Current Heart Failure Reports.

Basic and clinical neurocardiology

J. Andrew Armour, Jeffrey L. Ardell, J. Ardell, 2004 .

Neuromodulation targets intrinsic cardiac neurons to attenuate neuronally mediated atrial arrhythmias.

J. Ardell, J. Armour, D. Hoover, 2012, American journal of physiology. Regulatory, integrative and comparative physiology.

Dorsal spinal cord stimulation obtunds the capacity of intrathoracic extracardiac neurons to transduce myocardial ischemia

R. Cardinal, M. Vermeulen, J. Ardell, 2009, American journal of physiology. Regulatory, integrative and comparative physiology.

Preemptive, but not reactive, spinal cord stimulation mitigates transient ischemia-induced myocardial infarction via cardiac adrenergic neurons.

B. Linderoth, R. Foreman, J. Ardell, 2007, American journal of physiology. Heart and circulatory physiology.

Spinal cord stimulation suppresses bradycardias and atrial tachyarrhythmias induced by mediastinal nerve stimulation in dogs.

R. Cardinal, P. Pagé, M. Vermeulen, 2006, American journal of physiology. Regulatory, integrative and comparative physiology.

Modulation of intrinsic cardiac neurons by spinal cord stimulation: implications for its therapeutic use in angina pectoris.

S. S. Hull, K. Barron, B. Linderoth, 2000, Cardiovascular research.

Pulmonary and systemic blood flow contributions to upper airways in canine lung.

S. Barman, A. Taylor, J. Ardell, 1988, The American journal of physiology.

Differential responses accompanying sequential stimulation and ablation of vagal branches to dog heart.

W. C. Randall, D. Becker, J. Ardell, 1985, The American journal of physiology.

Recurrent myocardial infarction: Mechanisms of free-floating adaptation and autonomic derangement in networked cardiac neural control

K. Shivkumar, G. Kember, J. Ardell, 2017, PloS one.

Cardiac autonomic control in health and disease

K. Shivkumar, J. Ardell, 2016, The Journal of physiology.

Regional blood flow to canine parietal pleura and internal intercostal muscle.

J. Ardell, M. Townsley, D. Negrini, 1991, Journal of applied physiology.

Central-peripheral neural network interactions evoked by vagus nerve stimulation: functional consequences on control of cardiac function.

Pradeep S Rajendran, B. KenKnight, J. Ardell, 2015, American journal of physiology. Heart and circulatory physiology.

Chronic spinal cord stimulation modifies intrinsic cardiac synaptic efficacy in the suppression of atrial fibrillation

R. Cardinal, M. Vermeulen, J. Ardell, 2014, Autonomic Neuroscience.

Cardiovascular responses to graded reductions in hindlimb perfusion in exercising dogs.

L. Rowell, A. M. Scher, C. Wyss, 1983, The American journal of physiology.

Effects of dopamine and dobutamine on regional blood flow distribution in the neonatal piglet.

R. Powell, J. Ardell, J. Ferrara, 1995, Annals of surgery.

Vagal Nerve Stimulation Therapy: What Is Being Stimulated?

M. Zamir, G. Kember, J. Ardell, 2014, PloS one.

heterogeneity simulated in three dimensions Vascular tree structure affects lung blood flow

R. Glenny, M. Tawhai, K. Burrowes, 2015 .

Vascular tree structure affects lung blood flow heterogeneity simulated in three dimensions.

J. Ardell, J C Parker, J L Ardell, 1997, Journal of applied physiology.

Chronic decentralization of the heart differentially remodels canine intrinsic cardiac neuron muscarinic receptors.

J. Ardell, J. Armour, F. M. Smith, 2001, American journal of physiology. Heart and circulatory physiology.

Regional pulmonary blood flow during rest, tilt, and exercise in unanesthetized dogs.

S. Barman, J. Ardell, J C Parker, 1995, Journal of applied physiology.

N. Gurel, J. Ardell, J. Hadaya, 2022, Autonomic Neuroscience.

C2 spinal cord stimulation induces dynorphin release from rat T4 spinal cord: potential modulation of myocardial ischemia-sensitive neurons.

J. Ardell, Fang Hua, Xiaohui Ding, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Modulation of cardiac ischemia-sensitive afferent neuron signaling by preemptive C2 spinal cord stimulation: effect on substance P release from rat spinal cord.

Ryan J. McAuley, J. Ardell, Fang Hua, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Pre‐emptive, but not reactive, spinal cord stimulation mitigates transient ischemia induced myocardial infarction

J. Ardell, E. M. Southerland, J. Armour, 2006 .

Time-Resolved In Vivo Measurement of Neuropeptide Dynamics by Capacitive Immunoprobe in Porcine Heart.

J. Ardell, Shyue-An Chan, Corey Smith, 2022, Journal of visualized experiments : JoVE.

Inflammation, oxidative stress, and glial cell activation characterize stellate ganglia from humans with electrical storm.

N. Khanlou, K. Shivkumar, O. Ajijola, 2017, JCI insight.

Optical vagus nerve modulation of heart and respiration via heart-injected retrograde AAV

Gregory L. Futia, Arjun K. Fontaine, J. Caldwell, 2021, Scientific Reports.

Background pharmacological therapy in the ANTHEM‐HF: comparison to contemporary trials of novel heart failure therapies

B. KenKnight, L. DiCarlo, S. Mittal, 2019, ESC heart failure.

Vagal Nerve Stimulation Reduces Ventricular Arrhythmias and Mitigates Adverse Neural Cardiac Remodeling Post–Myocardial Infarction

K. Shivkumar, O. Ajijola, J. Ardell, 2023, JACC. Basic to translational science.

Spinal neuromodulation mitigates myocardial ischemia-induced sympathoexcitation by suppressing the intermediolateral nucleus hyperactivity and spinal neural synchrony

R. Foreman, J. Ardell, J. Armour, 2023, Frontiers in Neuroscience.

Neuronal Control of the Heart

R. Foreman, J. Ardell, 2009 .

Myocardial infarction induces structural and functional remodelling of the intrinsic cardiac nervous system

K. Shivkumar, O. Ajijola, M. Vaseghi, 2016, The Journal of physiology.

Central-peripheral neural network interactions evoked by vagus nerve stimulation: functional consequences on control of cardiac function.

B. KenKnight, J. Ardell, Pradeep S. Rajendran, 2015, American journal of physiology. Heart and circulatory physiology.

Recording and identification of cardiac neuron activity in the right atrium ganglionated plexus

Vincent Jacquemet, Eric Beaumont, Alain Vinet, 2013, Computing in Cardiology 2013.

Central vs. peripheral neuraxial sympathetic control of porcine ventricular electrophysiology.

Wei Zhou, A. Mahajan, K. Shivkumar, 2016, American journal of physiology. Regulatory, integrative and comparative physiology.

Sensory transduction of the ischemic myocardium.

J. Ardell, 2010, American journal of physiology. Heart and circulatory physiology.

Sensory Transduction of the Ischemic Myocardium Editorial Focus

J. Ardell, 2022 .

Mechanism of ventricular premature beats elicited by left stellate ganglion stimulation during acute ischaemia of the anterior left ventricle

T. Opthof, M. Janse, K. Shivkumar, 2020, Cardiovascular research.

A combined cuff electrode array for organ-specific selective stimulation of vagus nerve enabled by Electrical Impedance Tomography

K. Aristovich, J. Ardell, E. Ravagli, 2023, Frontiers in Medical Technology.

Scalable and reversible axonal neuromodulation of the sympathetic chain for cardiac control.

N. Bhadra, K. Shivkumar, N. Gurel, 2021, American journal of physiology. Heart and circulatory physiology.

Pathological effects of chronic myocardial infarction on peripheral neurons mediating cardiac neurotransmission

K. Shivkumar, E. Aliotta, O. Ajijola, 2016, Autonomic Neuroscience.

Thoracic spinal cord neuromodulation obtunds dorsal root ganglion afferent neuronal transduction of the ischemic ventricle.

J. Ardell, S. Salavatian, J. Armour, 2019, American journal of physiology. Heart and circulatory physiology.

Comparing the Memory Effects of 50-Hz Low-Frequency and 10-kHz High-Frequency Thoracic Spinal Cord Stimulation on Spinal Neural Network in a Myocardial Infarction Porcine Model.

J. Ardell, S. Salavatian, Y. Kuwabara, 2024, Neuromodulation : journal of the International Neuromodulation Society.

Redistribution of organ blood flow after hemorrhage and resuscitation in full-term piglets.

J. Ardell, W. Roberts, D. Dyess, 1994, Journal of pediatric surgery.