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Antitumor Activity of Targeted and Cytotoxic Agents in Murine Subcutaneous Tumor Models Correlates with Clinical Response

Harvey Wong, Cornelis E C A Hop, F. Theil, 2012, Clinical Cancer Research.

Interplay of Dissolution, Solubility, and Nonsink Permeation Determines the Oral Absorption of the Hedgehog Pathway Inhibitor GDC-0449 in Dogs: An Investigation Using Preclinical Studies and Physiologically Based Pharmacokinetic Modeling

Harvey Wong, Xiling Song, Cornelis E C A Hop, 2010, Drug Metabolism and Disposition.

A reversed sulfonamide series of selective RORc inverse agonists.

Bohdan Waszkowycz, Emanuela Gancia, Peter Lockey, 2014, Bioorganic & medicinal chemistry letters.

Systemic concentrations can limit the oral absorption of poorly soluble drugs: an investigation of non-sink permeation using physiologically based pharmacokinetic modeling.

Po-Chang Chiang, Harvey Wong, H. Wong, 2013, Molecular pharmaceutics.

Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).

Zhaoyang Wen, Brigitte Maurer, Vickie Tsui, 2012, Journal of medicinal chemistry.

Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety.

Xianrui Zhao, Ignacio Aliagas, Ronen Marmorstein, 2015, ACS medicinal chemistry letters.

SAHA Enhances Synaptic Function and Plasticity In Vitro but Has Limited Brain Availability In Vivo and Does Not Impact Cognition

Kimberly Scearce-Levie, Dani Brunner, Qiang Zhou, 2013, PloS one.