Alan Hruza

Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors.

Shuxia Zhao, Leigh Zawel, Stephen Fawell, 2013, Cancer discovery.

Structure-guided discovery of cyclin-dependent kinase inhibitors.

Emma Lees, David Parry, Kamil Paruch, 2008, Biopolymers.

Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry.

Ali Nahvi, Corey Strickland, J. Burchard, 2018, ACS chemical biology.

Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2.

Brian McKittrick, Yaolin Wang, Emma Lees, 2007, Bioorganic & medicinal chemistry letters.

Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity.

Marc Poirier, Michael W. Miller, Christian Mirescu, 2017, Journal of medicinal chemistry.

Structure of the Insulin Receptor-Insulin Complex by Single Particle CryoEM analysis

Bridget Carragher, Clinton S. Potter, Venkata P. Dandey, 2018, Nature.