Zhen-Yu J. Sun

发表

Solution structure of the CD3εδ ectodomain and comparison with CD3εγ as a basis for modeling T cell receptor topology and signaling

Gerhard Wagner, Ellis L. Reinherz, Amr Fahmy, 2004 .

Fast Assignment of 15N-HSQC Peaks using High-Resolution 3D HNcocaNH Experiments with Non-Uniform Sampling

Jeffrey C. Hoch, Gerhard Wagner, Dominique P. Frueh, 2005, Journal of biomolecular NMR.

TCR Mechanobiology: Torques and Tunable Structures Linked to Early T Cell Signaling

Gerhard Wagner, Ellis L. Reinherz, Matthew J. Lang, 2012, Front. Immun..

Structural analysis of human CEACAM1 oligomerization

G. Petsko, N. Beauchemin, R. Blumberg, 2022, Communications Biology.

High resolution X-ray and NMR structural study of human T-cell immunoglobulin and mucin domain containing protein-3

G. Petsko, G. Wagner, V. Kuchroo, 2018, Scientific Reports.

Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling

Clayton K. Collings, H. Seo, C. Woolf, 2019, Cell.

A nanobody that recognizes a 14-residue peptide epitope in the E2 ubiquitin-conjugating enzyme UBC6e modulates its activity

H. Ploegh, G. Wagner, Ross W. Cheloha, 2019, bioRxiv.

Autoinhibitory interaction in the multidomain adaptor protein Nck: possible roles in improving specificity and functional diversity.

G. Wagner, K. Takeuchi, Zhen-Yu J. Sun, 2010, Biochemistry.

Accelerated acquisition of high resolution triple-resonance spectra using non-uniform sampling and maximum entropy reconstruction.

A. Stern, J. Hoch, G. Wagner, 2004, Journal of magnetic resonance.

Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1α

D. Livingston, G. Wagner, A. Kung, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Importance of the CD3γ Ectodomain Terminal β-Strand and Membrane Proximal Stalk in Thymic Development and Receptor Assembly1

E. Reinherz, G. Wagner, W. Marissen, 2007, The Journal of Immunology.

Stalk in Thymic Development and Receptor-Strand and Membrane Proximal β Terminal Ectodomain γ Importance of the CD 3

E. Reinherz, G. Wagner, W. Marissen, 2007 .

Mechanisms Contributing to T Cell Receptor Signaling and Assembly Revealed by the Solution Structure of an Ectodomain Fragment of the CD3ϵγ Heterodimer

E. Reinherz, G. Wagner, Zhen-Yu J. Sun, 2001, Cell.

Specificity and Affinity of Sialic Acid Binding by the Rhesus Rotavirus VP8* Core

S. Harrison, P. Dormitzer, G. Wagner, 2002, Journal of Virology.

The rhesus rotavirus VP4 sialic acid binding domain has a galectin fold with a novel carbohydrate binding site

Gerhard Wagner, S. Harrison, P. Dormitzer, 2002, The EMBO journal.

Nitrogen-detected CAN and CON experiments as alternative experiments for main chain NMR resonance assignments

G. Wagner, D. Frueh, G. Heffron, 2010, Journal of biomolecular NMR.

Structure of a Heterophilic Adhesion Complex between the Human CD2 and CD58 (LFA-3) Counterreceptors

Gerhard Wagner, Jia-huai Wang, Ellis L Reinherz, 1999, Cell.

Viruses inhibit TIR gcADPR signaling to overcome bacterial defense

Gil Amitai, R. Sorek, P. J. Kranzusch, 2022, bioRxiv.

Structural basis for negative regulation of hypoxia-inducible factor-1α by CITED2

Gerhard Wagner, Andrew L Kung, G. Wagner, 2003, Nature Structural Biology.

A Zinc Clasp Structure Tethers Lck to T Cell Coreceptors CD4 and CD8

S. Blacklow, G. Wagner, M. Eck, 2003, Science.

Generation of Long-Lived Bone Marrow Plasma Cells Secreting Antibodies Specific for the HIV-1 gp41 Membrane-Proximal External Region in the Absence of Polyreactivity

J. C. Love, Todd M. Gierahn, D. Irvine, 2016, Journal of Virology.

Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy

K. Shah, H. Seo, R. Abdi, 2020, Cell.

Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75

A. Engelman, G. Wagner, P. Cherepanov, 2005, Nature Structural &Molecular Biology.

Structure of the VP16 Transactivator Target in ARC/Mediator

R. E. Luna, G. Wagner, A. Näär, 2010, Nature Structural &Molecular Biology.

Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity.

E. Reinherz, G. Wagner, K. Takeuchi, 2008, Journal of molecular biology.

A PHD Finger Motif in the C Terminus of RAG2 Modulates Recombination Activity*[boxs]

Sheryl K Elkin, G. Prestwich, Junying Yuan, 2005, Journal of Biological Chemistry.

Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization

E. Reinherz, G. Wagner, P. Kwong, 2011, Nature Structural &Molecular Biology.

Identification of potential microRNAs in glioblastoma using bioinformatic analysis and prognostic evaluation

Xiaofei Wang, Zhen-Yu J. Sun, Xuan Ding, 2020, Translational cancer research.

HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane.

V. Brusic, E. Reinherz, G. Wagner, 2008, Immunity.

Solution Structure of the Cuz1 AN1 Zinc Finger Domain: An Exposed LDFLP Motif Defines a Subfamily of AN1 Proteins

G. Wagner, H. Arthanari, M. Allan, 2016, PloS one.

Solution Structure of the Cuz1 AN1 Zinc Finger Domain: An Exposed LDFLP Motif Defines a Subfamily of AN1 Proteins

G. Wagner, H. Arthanari, M. Allan, 2016, PloS one.

Functional glycan‐free adhesion domain of human cell surface receptor CD58: design, production and NMR studies

E. Reinherz, V. Dötsch, G. Wagner, 1999, The EMBO journal.

Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface

E. Reinherz, G. Wagner, Jia-huai Wang, 2009, Proceedings of the National Academy of Sciences.

Covalently circularized nanodiscs for studying membrane proteins and viral entry

Andreas Plückthun, Thomas Walz, Gerhard Wagner, 2016, Nature Methods.

Auto-inhibitory interaction in the multidomain adaptor protein Nck: possible roles in improving specificity and functional diversity

G. Wagner, Zhen-Yu J Sun, K. Takeuchi, 2011 .

Conformational Stabilization and Rapid Labeling of a 29-Residue Peptide by a Small Molecule Reaction Partner.

B. Pentelute, Zhen-Yu J. Sun, Alexander J. Mijalis, 2019, Biochemistry.

Topological analysis of the gp41 MPER on lipid bilayers relevant to the metastable HIV-1 envelope prefusion state

E. Reinherz, G. Wagner, Jia-huai Wang, 2019, Proceedings of the National Academy of Sciences.

Disruption of helix-capping residues 671 and 674 reveals a role in HIV-1 entry for a specialized hinge segment of the membrane proximal external region of gp41.

V. Brusic, E. Reinherz, G. Wagner, 2014, Journal of molecular biology.

Immunogenicity of Membrane-bound HIV-1 gp41 Membrane-proximal External Region (MPER) Segments Is Dominated by Residue Accessibility and Modulated by Stereochemistry*

D. Irvine, E. Reinherz, G. Wagner, 2013, The Journal of Biological Chemistry.

Cryo-EM structure of an activated GPCR–G protein complex in lipid nanodiscs

Hao Wu, A. Plückthun, G. Wagner, 2020, Nature Structural & Molecular Biology.

High-Resolution Molecular and Antigen Structure of the VP8* Core of a Sialic Acid-Independent Human Rotavirus Strain

P. Dormitzer, B. Prasad, N. Monnier, 2006, Journal of Virology.

Sequence and structure evolved separately in a ribosomal ubiquitin variant

H. Ploegh, G. Wagner, Zhen-Yu J Sun, 2007, The EMBO journal.

Stereochemistry Residue Accessibility and Modulated by Region ( MPER ) Segments Is Dominated by HIV-1 gp 41 Membrane-proximal External Immunogenicity of Membrane-bound Immunology :

D. Irvine, E. Reinherz, G. Wagner, 2013 .

The αβ T Cell Receptor Is an Anisotropic Mechanosensor*

E. Reinherz, G. Wagner, C. Castro, 2009, The Journal of Biological Chemistry.

Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium

G. Petsko, V. Kuchroo, E. Sundberg, 2021, Communications Biology.

Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium

G. Petsko, G. Wagner, V. Kuchroo, 2020, bioRxiv.

Distinctive CD3 Heterodimeric Ectodomain Topologies Maximize Antigen-Triggered Activation of αβ T Cell Receptors

E. Reinherz, G. Wagner, Zhen-Yu J Sun, 2010, The Journal of Immunology.

Solution structure of the CD3epsilondelta ectodomain and comparison with CD3epsilongamma as a basis for modeling T cell receptor topology and signaling.

E. Reinherz, G. Wagner, Amr F Fahmy, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Generation of Long-Lived Bone Marrow Plasma Cells Secreting Antibodies Specific for the HIV-1 gp 41 Membrane-Proximal External Region in the Absence of Citation

J. C. Love, Todd M. Gierahn, D. Irvine, 2016 .

Non-uniformly sampled double-TROSY hNcaNH experiments for NMR sequential assignments of large proteins.

Gerhard Wagner, Dominique P Frueh, Jeffrey C Hoch, 2006, Journal of the American Chemical Society.

Structural and Functional Analysis of Human Cytomegalovirus US3 Protein

H. Ploegh, G. Wagner, S. Misaghi, 2004, Journal of Virology.

NMR resonance assignments of the catalytic domain of human serine/threonine phosphatase calcineurin in unligated and PVIVIT-peptide-bound states

G. Wagner, K. Takeuchi, Zhen-Yu J. Sun, 2015, Biomolecular NMR assignments.

NMR resonance assignments of the catalytic domain of human serine/threonine phosphatase calcineurin in unligated and PVIVIT-peptide-bound states

K. Takeuchi, Zhen-Yu J. Sun, M. Gal, 2014, Biomolecular NMR Assignments.

Structure of the calcineurin-NFAT complex: defining a T cell activation switch using solution NMR and crystal coordinates.

G. Wagner, M. Roehrl, K. Takeuchi, 2007, Structure.

Homotetrameric Structure of the SNAP-23 N-terminal Coiled-coil Domain*

M. Eck, H. Song, Yingwu Xu, 2003, The Journal of Biological Chemistry.

Alternate 13C-12C labeling for complete mainchain resonance assignments using C alpha direct-detection with applicability toward fast relaxing protein systems.

G. Wagner, Zhen-Yu J Sun, K. Takeuchi, 2008, Journal of the American Chemical Society.

Heterodimeric CD3epsilongamma extracellular domain fragments: production, purification and structural analysis.

Gerhard Wagner, Ellis L. Reinherz, E. Reinherz, 2000, Journal of molecular biology.

Multiple Conformations in the Ligand-binding Site of the Yeast Nuclear Pore-targeting Domain of Nup116p*

P. Silver, G. Wagner, J. Hogle, 2005, Journal of Biological Chemistry.

High-resolution 3D CANCA NMR experiments for complete mainchain assignments using C(alpha) direct detection.

S. Hyberts, G. Wagner, D. Frueh, 2010, Journal of the American Chemical Society.

Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2.

A. Kung, M. Eck, Zhen-Yu J. Sun, 2003, Nature structural biology.

High-resolution aliphatic side-chain assignments in 3D HCcoNH experiments with joint H–C evolution and non-uniform sampling

J. Hoch, S. Hyberts, G. Wagner, 2005, Journal of biomolecular NMR.

CACA-TOCSY with alternate 13C–12C labeling: a 13Cα direct detection experiment for mainchain resonance assignment, dihedral angle information, and amino acid type identification

G. Wagner, D. Frueh, Zhen-Yu J Sun, 2010, Journal of biomolecular NMR.

Three conformational states of the p300 CH1 domain define its functional properties.

Zhen-Yu J. Sun, S. Freedman, Ravina Dial, 2003, Biochemistry.