Bettina Groschel

发表

Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo

D. Irvine, W. Schief, S. Crotty, 2020, Immunity.

Modulating the quantity of HIV Env-specific CD4 T cell help promotes rare B cell responses in germinal centers

W. Schief, S. Crotty, M. Jenkins, 2020, The Journal of experimental medicine.

B cells expressing authentic naive human VRC01-class BCRs can be primed and recruited to germinal centers in multiple independent mouse models

W. Schief, D. Nemazee, S. Crotty, 2020, bioRxiv.

B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models

Allan C. deCamp, W. Schief, D. Nemazee, 2020, Proceedings of the National Academy of Sciences.

Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM

D. Baker, John P. Moore, D. Burton, 2021, Nature Communications.

A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity

D. Irvine, D. Burton, A. Belcher, 2021, Science Immunology.

From Structure to Sequence: Identification of polyclonal antibody families using cryoEM

W. Schief, A. Ward, S. Crotty, 2021, bioRxiv.

Use of the ecf1 gene to detect Shiga toxin-producing Escherichia coli in beef samples.

Bettina Groschel, K. Livezey, M. M. Becker, 2015, Journal of food protection.

Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors

Jordan R. Willis, J. Diedrich, J. Yates, 2022, Immunity.

B cells expressing IgM B cell receptors of HIV-1 neutralizing antibodies discriminate antigen affinities by sensing binding association rates

Md. Alamgir Hossain, W. Schief, L. Verkoczy, 2022, Cell reports.

Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses

D. Burton, K. Kirsch, W. Schief, 2022, Immunity.

6-Benzylamino 4-oxo-1,4-dihydro-1,8-naphthyridines and 4-oxo-1,4-dihydroquinolines as HIV integrase inhibitors.

Huanming Chen, A. Pinkerton, Samedy Ouk, 2011, Bioorganic & medicinal chemistry letters.

Lentiviral Vectors Interfering with Virus-Induced CD4 Down-Modulation Potently Block Human Immunodeficiency Virus Type 1 Replication in Primary Lymphocytes

D. Trono, J. Lama, Bettina Groschel, 2004, Journal of Virology.

Lymphocytes Virus Type 1 Replication in Primary Potently Block Human Immunodeficiency Virus-Induced CD 4 Down-Modulation Lentiviral Vectors Interfering with

D. Trono, J. Lama, Bettina Groschel, 2004 .

Cell Cycle Arrest in G2/M Promotes Early Steps of Infection by Human Immunodeficiency Virus

F. Bushman, Bettina Groschel, 2005, Journal of Virology.

Vaccination induces HIV broadly neutralizing antibody precursors in humans

Allan C. deCamp, Jordan R. Willis, D. Montefiori, 2022, Science.

Highly mutated antibodies capable of neutralizing N276 glycan-deficient HIV after a single immunization with an Env trimer

Xiaozhen Hu, W. Schief, O. Kalyuzhniy, 2022, Cell reports.

Highly Mutated Antibodies Capable of Neutralizing N276-Glycan Deficient HIV after a Single Immunization with an Env Trimer

W. Schief, O. Kalyuzhniy, M. Appel, 2021, SSRN Electronic Journal.

From structure to sequence: Antibody discovery using cryoEM

W. Schief, A. Ward, S. Crotty, 2022, Science advances.

DeGlyPHER: An Ultrasensitive Method for the Analysis of Viral Spike N-Glycoforms.

J. Diedrich, J. Yates, W. Schief, 2021, Analytical chemistry.

An ultrasensitive method for analysis of viral spike N-glycoforms

J. Diedrich, J. Yates, W. Schief, 2021, bioRxiv.

Multiplexed CRISPR/CAS9‐mediated engineering of pre‐clinical mouse models bearing native human B cell receptors

K. Kirsch, W. Schief, Yumiko Adachi, 2020, The EMBO journal.

6-Benzylamino 4-oxo-1,4-dihydro-1,8-naphthyridines and 4-oxo-1,4-dihydroquinolines as HIV integrase inhibitors.

Huanming Chen, A. Pinkerton, Samedy Ouk, 2011, Bioorganic & medicinal chemistry letters.

Diverse competitor B cell responses to a germline-targeting priming immunogen in human Ig loci transgenic mice

Daniel W. Kulp, J. Diedrich, W. Schief, 2024, bioRxiv.

A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates

D. Montefiori, W. Schief, R. Veazey, 2023, Nature communications.

mRNA-LNP prime boost evolves precursors toward VRC01-like broadly neutralizing antibodies in preclinical humanized mouse models

Jordan R. Willis, W. Schief, O. Kalyuzhniy, 2024, Science Immunology.