M. Kubitz

发表

Enhancing Humoral Responses Against HIV Envelope Trimers via Nanoparticle Delivery with Stabilized Synthetic Liposomes

Dong Soo Yun, Darrell J Irvine, William R Schief, 2018, Scientific Reports.

HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen

Joseph G. Jardine, Oleksandr Kalyuzhniy, Yumiko Adachi, 2016, Science.

Rosetta Antibody Design (RAbD): A General Framework for Computational Antibody Design

Brian D. Weitzner, Roland L. Dunbrack, Xiaozhen Hu, 2017, bioRxiv.

Identification of human antibody fragment clones specific for tetanus toxoid in a bacteriophage lambda immunoexpression library.

M. Alting-Mees, J. Short, A. Greener, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Long-lasting germinal center responses to a priming immunization with continuous proliferation and somatic mutation

D. Irvine, D. Burton, D. Montefiori, 2021, bioRxiv.

Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo

D. Nemazee, J. Paulson, N. Bovin, 2010, The Journal of experimental medicine.

Long-primed germinal centres with enduring affinity maturation and clonal migration

D. Irvine, D. Burton, D. Montefiori, 2022, Nature.

Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors

Jordan R. Willis, J. Diedrich, J. Yates, 2022, Immunity.

FusionGeneinGaucherDisease Implications fortheMolecular Anatomy,Pathogenesis, andDiagnosis ofthisDisorder

A. Zimran, C. West, J. Sorge, 1990 .

Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses

D. Burton, K. Kirsch, W. Schief, 2022, Immunity.

PREDICTION OF SEVERITY OF GAUCHER'S DISEASE BY IDENTIFICATION OF MUTATIONS AT DNA LEVEL

E. Beutler, A. Zimran, C. West, 1989, The Lancet.

Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design

Andreia M. Serra, D. Burton, I. Wilson, 2017, PLoS pathogens.

Global site-specific N-glycosylation analysis of HIV envelope glycoprotein

John R Yates, Yumiko Adachi, James C Paulson, 2017, Nature Communications.

Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice

Daniel W. Kulp, D. Burton, M. Nussenzweig, 2016, Cell.

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

David Nemazee, Joseph G. Jardine, Oleksandr Kalyuzhniy, 2016, Cell.

Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design

D. Burton, I. Wilson, W. Schief, 2016, PLoS pathogens.

Vaccination induces HIV broadly neutralizing antibody precursors in humans

Allan C. deCamp, Jordan R. Willis, D. Montefiori, 2022, Science.

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

Dong Soo Yun, Daniel W. Kulp, D. Irvine, 2016, Immunity.

RosettaAntibodyDesign (RAbD): A general framework for computational antibody design

Brian D. Weitzner, Roland L. Dunbrack, Jared Adolf-Bryfogle, 2017, bioRxiv.

A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses

Daniel W. Kulp, Jordan R. Willis, Xiaozhen Hu, 2019, Science.

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding

Daniel W. Kulp, Jordan R. Willis, Xiaozhen Hu, 2017, Nature Communications.

Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen

David Nemazee, Joseph G. Jardine, Oleksandr Kalyuzhniy, 2015, Science.

Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice

Daniel W. Kulp, D. Burton, A. Bradley, 2016, Science.

A glucocerebrosidase fusion gene in Gaucher disease. Implications for the molecular anatomy, pathogenesis, and diagnosis of this disorder.

E. Beutler, A. Zimran, C. West, 1990, The Journal of clinical investigation.

Enhancing Humoral Responses Against HIV Envelope Trimers via Nanoparticle Delivery with Stabilized Synthetic Liposomes

Dong Soo Yun, Daniel W. Kulp, D. Irvine, 2018, Scientific Reports.

Long-primed germinal centres with enduring affinity maturation and clonal migration

D. Irvine, D. Burton, D. Montefiori, 2022, Nature.

Expression of a heterodimeric Fab antibody protein in one cloning step.

J. Sorge, M. Kubitz, R. Mullinax, 1992, BioTechniques.

Correction: Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design

D. Burton, I. Wilson, W. Schief, 2016, PLoS pathogens.

Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo

D. Nemazee, J. Paulson, N. Bovin, 2010, The Journal of Experimental Medicine.

Diverse competitor B cell responses to a germline-targeting priming immunogen in human Ig loci transgenic mice

Daniel W. Kulp, J. Diedrich, W. Schief, 2024, bioRxiv.

A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates

D. Montefiori, W. Schief, R. Veazey, 2023, Nature communications.

Affinity gaps among B cells in germinal centers drive the selection of MPER precursors

W. Schief, O. Kalyuzhniy, Yumiko Adachi, 2024, Nature immunology.

mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies

W. Schief, O. Kalyuzhniy, Yumiko Adachi, 2024, Science.

mRNA-LNP prime boost evolves precursors toward VRC01-like broadly neutralizing antibodies in preclinical humanized mouse models

Jordan R. Willis, W. Schief, O. Kalyuzhniy, 2024, Science Immunology.