B. MacLachlan

发表

In Silico and Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility

S. Wells, A. Sewell, P. Rizkallah, 2018, Front. Immunol..

A pocket guide on how to structure SARS-CoV-2 drugs and therapies

J. Vivian, D. Littler, B. S. Gully, 2020, Biochemical Society transactions.

Neutrophilia, lymphopenia and myeloid dysfunction: a living review of the quantitative changes to innate and adaptive immune cells which define COVID-19 pathology

Jelena S. Bezbradica, Calliope A. Dendrou, Q. Sattentau, 2021, Oxford open immunology.

CD4+ T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features

A. Sewell, G. Dolton, P. Rizkallah, 2020, Cell reports.

Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope

T. Elliott, A. Sewell, G. Dolton, 2019, The Journal of Biological Chemistry.

Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C

J. Rossjohn, C. Retière, J. Vivian, 2021, Nature Communications.

The Role of the HLA Class I α2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1

J. Rossjohn, J. Vivian, Philippa M. Saunders, 2021, The Journal of Immunology.

Seven mysteries of LAG-3: a multi-faceted immune receptor of increasing complexity

A. Godkin, A. Gallimore, B. MacLachlan, 2021, Immunotherapy advances.

Molecular characterisation of CD4+ T cell responses to tumour antigens

B. MacLachlan, 2016 .

The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function

J. Rossjohn, A. Purcell, J. Vivian, 2020, Proceedings of the National Academy of Sciences.

Molecular characterization of HLA class II binding to the LAG‐3 T cell co‐inhibitory receptor

D. Cole, A. Greenshields-Watson, A. Godkin, 2020, European journal of immunology.

The nature of the human T cell response to the cancer antigen 5T4 is determined by the balance of regulatory and inflammatory T cells of the same antigen-specificity: implications for vaccine design

R. Hargest, A. Christian, A. Greenshields-Watson, 2018, Cancer Immunology, Immunotherapy.

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens

A. Sewell, P. Rizkallah, D. Cole, 2017, Journal of visualized experiments : JoVE.

Molecular Rules Underpinning Enhanced Affinity Binding of Human T Cell Receptors Engineered for Immunotherapy

A. Sewell, M. W. van der Kamp, C. Pudney, 2020, Molecular therapy oncolytics.

Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+ T cell immunity

A. Sewell, P. Rizkallah, A. Greenshields-Watson, 2023, Cell reports.

The role and uses of antibodies in COVID-19 infections: a living review

Jelena S. Bezbradica, Q. Sattentau, C. Fielding, 2021, Oxford open immunology.

Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope

T. Elliott, A. Sewell, G. Dolton, 2019, The Journal of Biological Chemistry.