K. Freeman

发表

Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation.

Mustafa Ozen, Michael Ittmann, B. Foster, 2003, Cancer research.

Regenerative protein thymosin β‐4 is a novel regulator of purinergic signaling

B. Zetter, B. R. Bowman, K. Freeman, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice.

M. Ittmann, B. Welm, J. Rosen, 2003, Cancer research.

Inducible dimerization of FGFR1

B. Welm, J. Rosen, A. Contreras, 2002, The Journal of cell biology.

703 Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary

B. Welm, J. Rosen, A. Contreras, 2002 .

Improved artificial death switches based on caspases and FADD.

T. Khan, D. Spencer, Elizabeth Pham, 1999, Human gene therapy.

An inducible system for the study of FGF signalling in early amphibian development.

B. Welm, J. Rosen, D. Spencer, 2003, Developmental biology.

Beta-thymosins in cancer: implications for the clinic.

J. Banyard, K. Freeman, 2009, Future oncology.

Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition.

Leif E. Peterson, M. Ittmann, Rile Li, 2007, Cancer cell.

MYCN induces neuroblastoma in primary neural crest cells

J. Rehg, D. Finkelstein, J. García-López, 2017, Oncogene.

Synthetic activation of caspases: artificial death switches.

D. Spencer, K. Freeman, R. A. MacCorkle, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Therapeutically targeting oncogenic CRCs facilitates induced differentiation of NB by RA and the BET bromodomain inhibitor

K. Freeman, Mellessa M. Miller, Satyanarayana Alleboina, 2021, Molecular therapy oncolytics.

A Cell Motility Screen Reveals Role for MARCKS-Related Protein in Adherens Junction Formation and Tumorigenesis

K. Freeman, A. Finlayson, 2009, PloS one.

Large 1p36 Deletions Affecting Arid1a Locus Facilitate Mycn-Driven Oncogenesis in Neuroblastoma

P. Northcott, J. Rehg, D. Finkelstein, 2020, Cell reports.

Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2

N. Greenberg, S. Winter, D. Spencer, 2007, Oncogene.

Antagonizing Bcl-2 Family Members Sensitizes Neuroblastoma and Ewing’s Sarcoma to an Inhibitor of Glutamine Metabolism

R. Olsen, K. Freeman, Z. Yin, 2015, PloS one.

XPO1 inhibition with selinexor synergizes with proteasome inhibition in neuroblastoma by targeting nuclear export of IkB

S. Master, B. Pawel, Y. Landesman, 2021, Translational oncology.

Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer

M. Roussel, Taosheng Chen, A. Shelat, 2020, Cancer Research.

Regenerative protein thymosin (cid:1) -4 is a novel regulator of purinergic signaling

B. Zetter, B. R. Bowman, K. Freeman, 2011 .

Metabolic reprogramming of cancer cells by JMJD 6-mediated pre-mRNA splicing is associated 1 with therapeutic response to splicing inhibitor 2 3

Shondra M. Pruett-Miller, Ji-Hoon Cho, D. Finkelstein, 2023 .

Gene-Editing Techniques

K. Freeman, 2019, Success in Academic Surgery: Basic Science.

Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor

Shondra M. Pruett-Miller, Ji-Hoon Cho, D. Finkelstein, 2023, bioRxiv.