C. Perruzzi

发表

Osteopontin expression and distribution in human carcinomas.

E. Manseau, H. Dvorak, B. Berse, 1994, The American journal of pathology.

A secreted phosphoprotein marker for neoplastic transformation of both epithelial and fibroblastic cells

H. Dvorak, C. Perruzzi, D. Senger, 1983, Nature.

Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid.

H. Dvorak, A. Dvorak, S. J. Galli, 1983, Science.

RhoB differentially controls Akt function in tumor cells and stromal endothelial cells during breast tumorigenesis.

A. Toker, G. Prendergast, O. Kocher, 2013, Cancer research.

Adhesive properties of osteopontin: regulation by a naturally occurring thrombin-cleavage in close proximity to the GRGDS cell-binding domain.

L. Water, A. Papadopoulos-Sergiou, C. Perruzzi, 1994, Molecular biology of the cell.

The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis.

M. Detmar, V. Koteliansky, A. D. de Fougerolles, 2002, The American journal of pathology.

The α1β1 and α2β1 Integrins Provide Critical Support for Vascular Endothelial Growth Factor Signaling, Endothelial Cell Migration, and Tumor Angiogenesis

M. Detmar, V. Koteliansky, A. D. Fougerolles, 2002 .

Secreted phosphoprotein markers for neoplastic transformation of human epithelial and fibroblastic cells.

C. Perruzzi, D. Senger, 1985, Cancer research.

Cell migration promoted by a potent GRGDS-containing thrombin-cleavage fragment of osteopontin.

C. Perruzzi, D. Senger, 1996, Biochimica et biophysica acta.

Thrombospondin-1 modulates VEGF-A-mediated Akt signaling and capillary survival in the developing retina.

B. Hopkins, J. Lawler, P. Bornstein, 2009, American journal of physiology. Heart and circulatory physiology.

Thrombospondin‐1 modulates vascular endothelial growth factor activity at the receptor level

H. Dvorak, J. Nagy, J. Lawler, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Elevated expression of secreted phosphoprotein I (osteopontin, 2ar) as a consequence of neoplastic transformation.

C. Perruzzi, D. Senger, A. Papadopoulos, 1989, Anticancer research.

The (cid:1) 1 (cid:2) 1 and (cid:1) 2 (cid:2) 1 Integrins Provide Critical Support for Vascular Endothelial Growth Factor Signaling, Endothelial Cell Migration, and Tumor Angiogenesis

M. Detmar, V. Koteliansky, A. D. Fougerolles, 2001 .

Functional Overlap and Cooperativity Among αv and β1 Integrin Subfamilies During Skin Angiogenesis

V. Koteliansky, A. D. Fougerolles, C. Perruzzi, 2003 .

Akt promotes Endocardial-Mesenchyme Transition

L. Benjamin, T. Camenisch, C. Perruzzi, 2009, Journal of angiogenesis research.

Osteopontin at the Tumor/Host Interface

L. Brown, L. Water, A. Papadopoulos-Sergiou, 1995, Annals of the New York Academy of Sciences.

Overexpression of MyrAkt1 in Endothelial Cells Leads to Erythropoietin- and BMP4-Independent Splenic Erythropoiesis in Mice

W. Aird, L. Benjamin, C. Perruzzi, 2013, PloS one.

Correction: Overexpression of MyrAkt1 in Endothelial Cells Leads to Erythropoietin- and BMP4-Independent Splenic Erythropoiesis in Mice

W. Aird, L. Benjamin, C. Perruzzi, 2013, PloS one.

Priming of the vascular endothelial growth factor signaling pathway by thrombospondin-1, CD36, and spleen tyrosine kinase.

R. Khosravi‐Far, J. Lawler, Keli Song, 2011, Blood.

VEGF-A/VEGFR Inhibition Restores Hematopoietic Homeostasis in the Bone Marrow and Attenuates Tumor Growth.

S. Rafii, W. Aird, L. Benjamin, 2016, Cancer research.

Palomid 529, a novel small-molecule drug, is a TORC1/TORC2 inhibitor that reduces tumor growth, tumor angiogenesis, and vascular permeability.

Q. Xue, B. Hopkins, L. Benjamin, 2008, Cancer research.

Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins.

M. Detmar, K. Claffey, J. Benes, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Expression and distribution of osteopontin in human tissues: widespread association with luminal epithelial surfaces.

E. Manseau, H. Dvorak, B. Berse, 1992, Molecular biology of the cell.

Purification of a human milk protein closely similar to tumor-secreted phosphoproteins and osteopontin.

D. Tenen, C. Perruzzi, D. Senger, 1989, Biochimica et biophysica acta.

Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.

M. Neeman, I. Shiojima, H. Dvorak, 2006, Cancer cell.

RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription

Santosh A. Khedkar, G. Prendergast, M. Klagsbrun, 2013, Nature Communications.

A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines.

H. Dvorak, J. Feder, C. Perruzzi, 1986, Cancer research.

Low IGF-I suppresses VEGF-survival signaling in retinal endothelial cells: Direct correlation with clinical retinopathy of prematurity

Lois E. H. Smith, D. Leroith, B. Carlsson, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor

Lois E. H. Smith, Samuel E. Driver, S. Soker, 1999, Nature Medicine.

Secreted phosphoproteins associated with neoplastic transformation: close homology with plasma proteins cleaved during blood coagulation.

D. Tenen, C. Perruzzi, D. Senger, 1988, Cancer research.

Molecular profiling of angiogenesis markers.

Lois E. H. Smith, K. Desai, I. Ali, 2002, The American journal of pathology.

Akt1 and akt3 exert opposing roles in the regulation of vascular tumor growth.

Q. Xue, D. Lev, L. Benjamin, 2014, Cancer research.

Technical Advance Molecular Profiling of Angiogenesis Markers

Lois E. H. Smith, K. Desai, I. Ali, 2002 .

Vascular tumors have increased p70 S6-kinase activation and are inhibited by topical rapamycin

D. Lev, T. Phung, C. Perruzzi, 2013, Laboratory Investigation.

T24 human bladder carcinoma cells with activated Ha-ras protooncogene: nontumorigenic cells susceptible to malignant transformation with carcinogen.

I. Ali, C. Perruzzi, D. Senger, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Functional overlap and cooperativity among alphav and beta1 integrin subfamilies during skin angiogenesis.

V. Koteliansky, A. D. de Fougerolles, C. Perruzzi, 2003, The Journal of investigative dermatology.

Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin.

M. Detmar, K. Claffey, S. Ledbetter, 1996, The American journal of pathology.

Expression and distribution of osteopontin in human tissues: widespread association with luminal epithelial surfaces.

E. Manseau, H. Dvorak, B. Berse, 1992, Molecular biology of the cell.

Palomid 529, a novel small-molecule drug, is a TORC1/TORC2 inhibitor that reduces tumor growth, tumor angiogenesis, and vascular permeability.

Q. Xue, B. Hopkins, L. Benjamin, 2008, Cancer research.