B. Woolbright

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Osteopontin is an initial mediator of inflammation and liver injury during obstructive cholestasis after bile duct ligation in mice.

Hartmut Jaeschke, H. Jaeschke, A. Ramachandran, 2014, Toxicology letters.

Disruption of Estrogen Receptor Alpha in Rats Results in Faster Initiation of Compensatory Regeneration Despite Higher Liver Injury After Carbon Tetrachloride Treatment

Hartmut Jaeschke, Udayan Apte, H. Jaeschke, 2017, International journal of toxicology.

Prostaglandin E2 as a Therapeutic Target in Bladder Cancer: From Basic Science to Clinical Trials.

John A. Taylor, B. Woolbright, C. Pilbeam, 2020, Prostaglandins & other lipid mediators.

Critical Factors in the Assessment of Cholestatic Liver Injury In Vitro.

H. Jaeschke, B. Woolbright, 2015, Methods in molecular biology.

Inflammation: Cause or consequence of chronic cholestatic liver injury.

B. Woolbright, 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

INFLAMMATION AND CELL DEATH DURING CHOLESTASIS: THE EVOLVING ROLE OF BILE ACIDS.

H. Jaeschke, B. Woolbright, 2019, Gene expression.

Bladder cancer, inflammageing and microbiomes

M. Ingersoll, John A. Taylor, S. Umar, 2022, Nature Reviews Urology.

Sortilin 1 Loss-of-Function Protects Against Cholestatic Liver Injury by Attenuating Hepatic Bile Acid Accumulation in Bile Duct Ligated Mice

H. Jaeschke, Tiangang Li, B. Woolbright, 2018, Toxicological sciences : an official journal of the Society of Toxicology.

Alcoholic Hepatitis: Lost in Translation

H. Jaeschke, B. Woolbright, 2017, Journal of clinical and translational hepatology.

Generation of Pro- and Anti-Inflammatory Mediators after Acetaminophen Overdose in Surviving and Non-Surviving Patients.

Mitchell R. McGill, H. Jaeschke, Nga T. Nguyen, 2022, Toxicology letters.

Mechanisms of Inflammatory Liver Injury and Drug-Induced Hepatotoxicity

H. Jaeschke, B. Woolbright, 2018, Current Pharmacology Reports.

Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis.

H. Jaeschke, K. Dorko, S. Kumer, 2015, Toxicology and applied pharmacology.

Therapeutic targets for cholestatic liver injury

H. Jaeschke, B. Woolbright, 2016, Expert opinion on therapeutic targets.

Bladder cancer, inflammageing and microbiomes

M. Ingersoll, John A. Taylor, S. Umar, 2022, Nature Reviews Urology.

Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy.

H. Jaeschke, B. Copple, J. Luyendyk, 2014, Journal of hepatology.

Bile Acid‐Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human Hepatocytes

Mitchell R. McGill, H. Jaeschke, Hui-min Yan, 2016, Basic & clinical pharmacology & toxicology.

Lithocholic acid feeding results in direct hepato-toxicity independent of neutrophil function in mice.

H. Jaeschke, M. Trauner, Feng Li, 2014, Toxicology letters.

Specific regulation of CYP27B1 and VDR in proximal versus distal renal cells.

A. Bajwa, B. Woolbright, M. Beckman, 2008, Archives of biochemistry and biophysics.

Lysosomal Instability and Cathepsin B Release during Acetaminophen Hepatotoxicity

Mitchell R. McGill, H. Jaeschke, A. Ramachandran, 2012, Basic & clinical pharmacology & toxicology.

Correction to: Direct Amplification of Tissue Factor:Factor VIIa Procoagulant Activity by Bile Acids Drives Intrahepatic Coagulation.

H. Jaeschke, J. Luyendyk, M. Olyaee, 2019, Arteriosclerosis, thrombosis, and vascular biology.

Human Wharton's Jelly-derived mesenchymal stem cells prevent acetaminophen-induced liver injury in a mouse model unlike human dermal fibroblasts

H. Jaeschke, A. Ramachandran, U. Apte, 2022, Archives of Toxicology.

Genomic heterogeneity in bladder cancer: challenges and possible solutions to improve outcomes

H. Al-Ahmadie, D. McConkey, L. Dyrskjøt, 2020, Nature Reviews Urology.

Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity.

Mitchell R. McGill, T. Asselah, H. Jaeschke, 2017, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Role of the inflammasome in acetaminophen-induced liver injury and acute liver failure.

H. Jaeschke, B. Woolbright, 2017, Journal of hepatology.

Fosciclopirox suppresses growth of high-grade urothelial cancer by targeting the γ-secretase complex

P. Rangarajan, R. Jensen, S. Anant, 2021, Cell Death & Disease.

Current strategies to minimize hepatic ischemia-reperfusion injury by targeting reactive oxygen species.

H. Jaeschke, B. Woolbright, 2012, Transplantation reviews.

Metabolic Flexibility in Cancer: Targeting the Pyruvate Dehydrogenase Kinase:Pyruvate Dehydrogenase Axis

Robert A. Harris, John A. Taylor, B. Woolbright, 2019, Molecular Cancer Therapeutics.

Mechanisms of Acetaminophen-Induced Liver Injury

H. Jaeschke, B. Woolbright, 2017 .

Plasma biomarkers of liver injury and inflammation demonstrate a lack of apoptosis during obstructive cholestasis in mice.

Hartmut Jaeschke, H. Jaeschke, R. Jenkins, 2013, Toxicology and applied pharmacology.

Metabolic changes in bladder cancer.

John A. Taylor, B. Woolbright, M. Ayres, 2018, Urologic oncology.

MIF family proteins in genitourinary cancer: tumorigenic roles and therapeutic potential

John A. Taylor, B. Woolbright, S. Weir, 2019, Nature Reviews Urology.

The Role of Pyruvate Dehydrogenase Kinase-4 (PDK4) in Bladder Cancer and Chemoresistance

John A. Taylor, D. Choudhary, Erika Abbott, 2018, Molecular Cancer Therapeutics.

Differential susceptibility to acetaminophen-induced liver injury in sub-strains of C57BL/6 mice: 6N versus 6J.

H. Jaeschke, M. Bourdi, B. Woolbright, 2016, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Glycodeoxycholic acid levels as prognostic biomarker in acetaminophen-induced acute liver failure patients.

William M. Lee, Mitchell R. McGill, H. Jaeschke, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Mice deficient in pyruvate dehydrogenase kinase 4 are protected against acetaminophen-induced hepatotoxicity.

H. Jaeschke, A. Ramachandran, B. Woolbright, 2019, Toxicology and applied pharmacology.

Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity

H. Jaeschke, A. Ramachandran, W. Ding, 2018, Archives of Toxicology.

Mechanisms of Inflammatory Liver Injury and Drug-Induced Hepatotoxicity

H. Jaeschke, B. Woolbright, 2018, Current Pharmacology Reports.

Mechanisms of Inflammatory Liver Injury and Drug-Induced Hepatotoxicity

H. Jaeschke, B. Woolbright, 2018, Current Pharmacology Reports.

Is Keratin-18 only a Marker of Cell Death in Acute-On-Chronic Liver Failure?

H. Jaeschke, B. Woolbright, 2018, Journal of laboratory and precision medicine.

Biomarkers of Mitochondrial Injury After Acetaminophen Overdose

H. Jaeschke, B. Woolbright, 2018 .

Novel insight into mechanisms of cholestatic liver injury.

Hartmut Jaeschke, H. Jaeschke, B. Woolbright, 2012, World journal of gastroenterology.

Pyruvate Dehydrogenase Kinase 4 Deficiency Increases Tumorigenesis in a Murine Model of Bladder Cancer

John A. Taylor, Katie Dennis, B. Woolbright, 2023, Cancers.

Role of MIF1/MIF2/CD74 interactions in bladder cancer

Xiaogang Li, J. Warrick, John A. Taylor, 2022, The Journal of pathology.

SATB1 and bladder cancer: Is there a functional link?

John A. Taylor, D. Choudhary, B. Woolbright, 2017, Urologic oncology.

Plasma biomarkers to study mechanisms of liver injury in patients with hypoxic hepatitis

Mitchell R. McGill, H. Jaeschke, R. Jenkins, 2017, Liver international : official journal of the International Association for the Study of the Liver.

Xenobiotic and Endobiotic Mediated Interactions Between the Cytochrome P450 System and the Inflammatory Response in the Liver.

H. Jaeschke, B. Woolbright, 2015, Advances in pharmacology.

Mechanistic Biomarkers in Liver Diseases

Hartmut Jaeschke, Mitchell R. McGill, H. Jaeschke, 2017 .

Caspase inhibitors for the treatment of liver disease: friend or foe?

H. Jaeschke, W. Ding, B. Woolbright, 2017, Expert review of gastroenterology & hepatology.

Caspase Inhibition Prevents Tumor Necrosis Factor-α-Induced Apoptosis and Promotes Necrotic Cell Death in Mouse Hepatocytes in Vivo and in Vitro.

Mitchell R. McGill, H. Jaeschke, W. Ding, 2016, The American journal of pathology.

Late Protective Effect of Netrin-1 in the Murine Acetaminophen Hepatotoxicity Model.

H. Jaeschke, A. Ramachandran, B. Woolbright, 2020, Toxicological sciences : an official journal of the Society of Toxicology.

The impact of sterile inflammation in acute liver injury

H. Jaeschke, B. Woolbright, 2017, Journal of clinical and translational research.

Natural products as a means of overcoming cisplatin chemoresistance in bladder cancer

John A. Taylor, B. Woolbright, G. Rajendran, 2020, Cancer drug resistance.

Measuring Apoptosis and Necrosis in Cholestatic Liver Injury.

H. Jaeschke, B. Woolbright, 2019, Methods in molecular biology.

Molecular subtyping of bladder cancer: current trends and future directions in 2019

John A. Taylor, B. Woolbright, W. Smelser, 2019, Current opinion in urology.

Tumor M2-PK: A novel urine marker of bladder cancer

G. Kaushik, S. Anant, John A. Taylor, 2019, PloS one.

PDK2: An Underappreciated Regulator of Liver Metabolism

Robert A. Harris, B. Woolbright, 2021, Livers.

Sterile inflammation in acute liver injury: myth or mystery?

H. Jaeschke, B. Woolbright, 2015, Expert review of gastroenterology & hepatology.

Cell Death and Prognosis of Mortality in Alcoholic Hepatitis Patients Using Plasma Keratin-18.

H. Jaeschke, S. Weinman, B. Woolbright, 2017, Gene expression.

Role of heme oxygenase 1 in TNF/TNF receptor-mediated apoptosis after hepatic ischemia/reperfusion in rats. Shock 39: 380-388, 2013.

H. Jaeschke, B. Woolbright, 2013, Shock.

Heme oxygenase‐1 and platelets in hepatic ischemia reperfusion injury

H. Jaeschke, B. Woolbright, 2013, Journal of gastroenterology and hepatology.

Microcystin‐LR induced liver injury in mice and in primary human hepatocytes is caused by oncotic necrosis

H. Jaeschke, S. Kumer, B. Woolbright, 2017, Toxicon : official journal of the International Society on Toxinology.

Lack of Direct Cytotoxicity of Extracellular ATP against Hepatocytes: Role in the Mechanism of Acetaminophen Hepatotoxicity.

Mitchell R. McGill, H. Jaeschke, K. Dorko, 2015, Journal of clinical and translational research.

Acetaminophen-induced injury and acute liver failure as a clinically relevant model Acetaminophen- (APAP) induced acute liver failure (ALF) is a major cause of morbidity and mortality in the US (1)

H. Jaeschke, B. Woolbright, 2016 .

Neurologic cues modulate immune‐mediated liver injury and regeneration

H. Jaeschke, B. Woolbright, 2016, Hepatology.

Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy.

H. Jaeschke, B. Copple, J. Luyendyk, 2014, Journal of hepatology.

Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity

H. Jaeschke, A. Ramachandran, W. Ding, 2018, Archives of Toxicology.

Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity.

Mitchell R. McGill, T. Asselah, H. Jaeschke, 2017, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Differential susceptibility to acetaminophen-induced liver injury in sub-strains of C57BL/6 mice: 6N versus 6J.

H. Jaeschke, M. Bourdi, B. Woolbright, 2016, Food and Chemical Toxicology.

Direct Amplification of TF (Tissue Factor).

H. Jaeschke, J. Luyendyk, M. Olyaee, 2019, Arteriosclerosis, thrombosis, and vascular biology.

Direct amplification of tissue factor:factor VIIa procoagulant activity by bile acids drives intrahepatic coagulation

J. Luyendyk, M. Olyaee, A. Kopec, 2019 .

Plasma biomarkers of liver injury and inflammation demonstrate a lack of apoptosis during obstructive cholestasis in mice.

H. Jaeschke, B. Woolbright, M. Bajt, 2013, Toxicology and applied pharmacology.

Lack of Direct Cytotoxicity of Extracellular ATP against Hepatocytes: Role in the Mechanism of Acetaminophen Hepatotoxicity.

Mitchell R. McGill, H. Jaeschke, K. Dorko, 2015, Journal of clinical and translational research.

Lack of direct cytotoxicity of extracellular ATP against hepatocytes: role in the mechanism of acetaminophen hepatotoxicity

Mitchell R. McGill, H. Jaeschke, K. Dorko, 2015, Journal of clinical and translational research.

Understanding the microbiome as a mediator of bladder cancer progression and therapeutic response.

B. Woolbright, Mahgol Golshani, John A Taylor, 2024, Urologic oncology.

Aging induces changes in cancer formation and microbial content in a murine model of bladder cancer.

Cuncong Zhong, Erika Abbott, B. Woolbright, 2024, GeroScience.

Preclinical models of bladder cancer: BBN and beyond.

B. Woolbright, John A Taylor, David Matye, 2024, Nature reviews. Urology.