J. Chapman

发表

Osteopontin Is Required for the Early Onset of High Fat Diet-Induced Insulin Resistance in Mice

Dorothy D. Sears, D. Sears, J. Ofrecio, 2010, PloS one.

12/15-Lipoxygenase Is Required for the Early Onset of High Fat Diet-Induced Adipose Tissue Inflammation and Insulin Resistance in Mice

Dorothy D. Sears, D. Sears, J. Ofrecio, 2009, PloS one.

Demonstration of Proof of Mechanism and Pharmacokinetics and Pharmacodynamic Relationship with 4′-Cyano-biphenyl-4-sulfonic Acid (6-Amino-pyridin-2-yl)-amide (PF-915275), an Inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1, in Cynomolgus Monkeys

A. Fanjul, P. Rejto, P. Stewart, 2008, Journal of Pharmacology and Experimental Therapeutics.

Multi-tissue, selective PPARγ modulation of insulin sensitivity and metabolic pathways in obese rats.

Dorothy D. Sears, S. Subramaniam, D. Sears, 2011, American journal of physiology. Endocrinology and metabolism.

Rat glutathione S-transferase M4-4: an isoenzyme with unique structural features including a redox-reactive cysteine-115 residue that forms mixed disulphides with glutathione.

M. Tien, H. Cheng, Y. Patskovsky, 2001, The Biochemical journal.

Selective modulation of promoter recruitment and transcriptional activity of PPARgamma.

Dorothy D. Sears, J. Olefsky, D. Sears, 2007, Biochemical and biophysical research communications.

Differing cardioprotective efficacy of the Na+/Ca2+ exchanger inhibitors SEA0400 and KB-R7943.

J. Chapman, G. Deshmukh, M. Deninno, 2003, American journal of physiology. Heart and circulatory physiology.

A novel nonpeptidic caspase-3/7 inhibitor, (S)-(+)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin reduces myocardial ischemic injury.

A. Milici, J. Chapman, H. Stukenbrok, 2002, European journal of pharmacology.

Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia.

T. Ganz, E. Nemeth, M. Nasoff, 2015, Blood.

Isozyme-nonselective N-Substituted Bipiperidylcarboxamide Acetyl-CoA Carboxylase Inhibitors Reduce Tissue Malonyl-CoA Concentrations, Inhibit Fatty Acid Synthesis, and Increase Fatty Acid Oxidation in Cultured Cells and in Experimental Animals*

D. Hargrove, D. Dalvie, J. Chapman, 2003, Journal of Biological Chemistry.

Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1).

Justin Chapman, Laura Lingardo, Dario R Alessi, 2010, The Biochemical journal.

Functional Heterogeneity of CD11c-positive Adipose Tissue Macrophages in Diet-induced Obese Mice*

Dorothy D. Sears, S. Watkins, J. Olefsky, 2010, The Journal of Biological Chemistry.

Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals.

J. Olefsky, J. Chapman, J. Neels, 2008, Cell Metabolism.

Sphingomyelin-derived lipids differentially regulate the extracellular signal-regulated kinase 2 (ERK-2) and c-Jun N-terminal kinase (JNK) signal cascades in airway smooth muscle.

S. Pyne, N. Pyne, J. Chapman, 1996, European journal of biochemistry.

Viral‐Mediated Gene Delivery Of Constitutively Activated GΑS Alters Vasoreactivity

K. Neve, R. Neve, S. Mader, 2000 .

Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals.

J. Olefsky, J. Chapman, J. Neels, 2008, Cell metabolism.