M. Horsch

发表

Identification of coexpressed gene clusters in a comparative analysis of transcriptome and proteome in mouse tissues.

A. Harder, M. D. de Angelis, J. Beckers, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Health Effects of Ambient Particulate Matter—Biological Mechanisms and Inflammatory Responses to In Vitro and In Vivo Particle Exposures

Susanne Krauss-Etschmann, Johannes Beckers, Silvia Diabaté, 2008 .

High Mobility Group N Proteins Modulate the Fidelity of the Cellular Transcriptional Profile in a Tissue- and Variant-specific Manner*

H. Fuchs, D. Busch, I. Ovcharenko, 2013, The Journal of Biological Chemistry.

Specificity assessment from fractionation experiments (SAFE): a novel method to evaluate microarray probe specificity based on hybridisation stringencies.

Volkmar Liebscher, Johannes Beckers, Martin Hrabé de Angelis, 2003, Nucleic acids research.

Mitochondrial Dysfunction and Decrease in Body Weight of a Transgenic Knock-in Mouse Model for TDP-43*

H. Fuchs, S. Koob, A. Reichert, 2014, The Journal of Biological Chemistry.

T Cells + and CD 8 + of CD 4 Differential Kinetics of Antigen Dependency

R. Obst, J. Beckers, J. Ellwart, 2014 .

Systemic first-line phenotyping.

H. Fuchs, D. Busch, E. Wolf, 2009, Methods in molecular biology.

The German Mouse Clinic: a platform for systemic phenotype analysis of mouse models.

H. Fuchs, D. Busch, K. Schughart, 2009, Current pharmaceutical biotechnology.

The German Mouse Clinic – Running an Open Access Platform

H. Fuchs, M. Angelis, D. Busch, 2011 .

Mouse phenotyping.

H. Fuchs, D. Busch, E. Wolf, 2011, Methods.

Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice

H. Fuchs, E. Wolf, M. H. Angelis, 2016, Journal of Inherited Metabolic Disease.

"Sighted C3H" mice--a tool for analysing the influence of vision on mouse behaviour?

H. Fuchs, W. Wurst, M. Kallnik, 2008, Frontiers in bioscience : a journal and virtual library.

Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia

H. Fuchs, E. Wolf, J. Taipale, 2011, Journal of Cell Science.

Innovations in phenotyping of mouse models in the German Mouse Clinic

H. Fuchs, D. Busch, H. Höfler, 2012, Mammalian Genome.

Standardized, Systemic Phenotypic Analysis of Umod C93F and Umod A227T Mutant Mice

H. Fuchs, D. Busch, E. Wolf, 2013, PloS one.

Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia

H. Fuchs, D. Hladik, M. Irmler, 2019, Experimental eye research.

A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes

J. Mason, H. Fuchs, D. Busch, 2020, Mammalian Genome.

Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression

W. Rottbauer, H. Fuchs, D. Busch, 2016, Nature Communications.

Pitx3 directly regulates Foxe3 during early lens development.

P. Carlsson, J. Beckers, J. Graw, 2013, The International journal of developmental biology.

Murine tissue factor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality.

H. Fuchs, A. Akhmedov, E. Wolf, 2019, Haematologica.

Uncoupling Malt1 threshold function from paracaspase activity results in destructive autoimmune inflammation.

M. Kriegsmann, W. Weichert, W. Wurst, 2014, Cell reports.

Mouse Genetics and Metabolic Mouse Phenotyping

H. Fuchs, M. Angelis, D. Busch, 2012 .

Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain.

H. Fuchs, D. Busch, F. Staal, 2011, Blood.

Restless Legs Syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon

C. Gieger, M. Waldenberger, H. Fuchs, 2014, Genome research.

Cardioprotection and lifespan extension by the natural polyamine spermidine

Stephan J Sigrist, Christian Mühlfeld, Slaven Stekovic, 2016, Nature Medicine.

Pleiotropic effects in Eya3 knockout mice

H. Fuchs, E. Wolf, W. Wurst, 2008, BMC Developmental Biology.

Dll1 Haploinsufficiency in Adult Mice Leads to a Complex Phenotype Affecting Metabolic and Immunological Processes

Gerhard K. H. Przemeck, H. Fuchs, D. Busch, 2009, PloS one.

Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling.

A. Harder, J. Beckers, F. Lottspeich, 2005, Gene expression patterns : GEP.

Systematic gene expression profiling of mouse model series reveals coexpressed genes

H. Fuchs, M. D. de Angelis, J. Beckers, 2008, Proteomics.

Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis.

H. Fuchs, E. Wolf, M. D. de Angelis, 2013, Molecular metabolism.

Comparative analysis of nuclear transfer embryo-derived mouse embryonic stem cells. Part II: gene regulation.

J. Beckers, A. Dinnyés, M. Horsch, 2012, Cellular reprogramming.

Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression

H. Fuchs, E. Wolf, G. Kollias, 2017, Scientific Reports.

Functional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancers

D. Landsman, H. Fuchs, A. van der Velde, 2015, Genome research.

Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia

Gerhard K. H. Przemeck, H. Fuchs, T. Wieland, 2016, Mammalian Genome.

MiR‐34a deficiency accelerates medulloblastoma formation in vivo

H. Fuchs, M. H. Angelis, W. Wurst, 2015, International journal of cancer.

Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis.

K. Suhre, G. Kastenmüller, J. Adamski, 2016, Archives of biochemistry and biophysics.

Rapamycin extends murine lifespan but has limited effects on aging.

H. Fuchs, D. Busch, H. Höfler, 2013, The Journal of clinical investigation.

Introducing the German Mouse Clinic: open access platform for standardized phenotyping

Werner Müller, Christian Zybill, Valérie Gailus-Durner, 2005, Nature Methods.

Prion-induced Activation of Cholesterogenic Gene Expression by Srebp2 in Neuronal Cells*

J. Beckers, G. Hajj, S. Brodesser, 2009, The Journal of Biological Chemistry.

Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines

H. Fuchs, J. Beckers, V. Gailus-Durner, 2015, PloS one.

Peroxidasin is essential for eye development in the mouse

H. Fuchs, J. Beckers, V. Gailus-Durner, 2014, Human molecular genetics.

Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels

H. Fuchs, E. Wolf, M. Muckenthaler, 2015, BioMetals.

Cardiopulmonary dysfunction in the Osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms

Gerhard K. H. Przemeck, H. Fuchs, W. Wurst, 2012, Human molecular genetics.

Loss of the Actin Remodeler Eps8 Causes Intestinal Defects and Improved Metabolic Status in Mice

H. Fuchs, E. Wolf, C. Tacchetti, 2010, PloS one.

Overexpressed vs mutated Kras in murine fibroblasts: a molecular phenotyping study

B. Seliger, J. Beckers, M. Hrabě de Angelis, 2009, British Journal of Cancer.

SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities.

H. Fuchs, D. Busch, E. Wolf, 2013, DNA repair.

Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice

H. Fuchs, A. Walch, M. Aichler, 2016, PloS one.

Prdm6 Is Essential for Cardiovascular Development In Vivo

Gerhard K. H. Przemeck, M. Dyer, H. Dodt, 2013, PloS one.

A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes

J. Mason, H. Fuchs, D. Busch, 2020, Mammalian Genome.

Health effects of ambient particulate matter--biological mechanisms and inflammatory responses to in vitro and in vivo particle exposures.

Susanne Krauss-Etschmann, Johannes Beckers, Silvia Diabaté, 2008, Inhalation toxicology.

The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations

Gerhard K. H. Przemeck, H. Fuchs, D. Busch, 2016, G3: Genes, Genomes, Genetics.

Differential Kinetics of Antigen Dependency of CD4+ and CD8+ T Cells

R. Obst, J. Beckers, J. Ellwart, 2014, The Journal of Immunology.

Identification and validation of novel ERBB2 (HER2, NEU) targets including genes involved in angiogenesis

Johannes Beckers, Felix Herrmann, Martin Hrabé de Angelis, 2005, International journal of cancer.

Novel allele of crybb2 in the mouse and its expression in the brain.

Wolfgang Wurst, Johannes Beckers, Marion Horsch, 2008, Investigative ophthalmology & visual science.

Cell line dependent RNA expression profiles of prion-infected mouse neuronal cells.

Johannes Beckers, Marion Horsch, A. Stengel, 2005, Journal of molecular biology.

Assessment of a systematic expression profiling approach in ENU-induced mouse mutant lines

Martin Hrabé de Angelis, Johannes Beckers, Marion Horsch, 2004, Mammalian Genome.

Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia

Gerhard K. H. Przemeck, H. Fuchs, T. Wieland, 2016, Mammalian Genome.

The hepatic phosphatidylcholine transporter ABCB4 as modulator of glucose homeostasis

H. Fuchs, E. Wolf, F. Lammert, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1I27N mutant mice

H. Fuchs, S. Hölter, J. Beckers, 2017, Journal of Biomedical Science.

CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection

H. Fuchs, D. Busch, T. Laajala, 2016, PloS one.

alters enhancer function in the developing telencephalon Meis 1 Restless Legs Syndrome-associated intronic common variant in Material Supplemental

C. Gieger, M. Waldenberger, H. Fuchs, 2014 .

Generation of Mice Lacking DUF1220 Protein Domains: Effects on Fecundity and Hyperactivity

J. Sikela, W. Wurst, M. D. de Angelis, 2014, Mammalian Genome.

Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice

H. Fuchs, D. Busch, E. Wolf, 2016, PloS one.

Innovations in phenotyping of mouse models in the German Mouse Clinic

H. Fuchs, D. Busch, H. Höfler, 2012, Mammalian Genome.

Requirement of the RNA-editing Enzyme ADAR2 for Normal Physiology in Mice*

H. Fuchs, D. Busch, P. Seeburg, 2011, The Journal of Biological Chemistry.

Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1I27N mutant mice

H. Fuchs, E. Wolf, S. Hölter, 2017, Journal of Biomedical Science.

Microphthalmia, parkinsonism, and enhanced nociception in Pitx3416insG mice

H. Fuchs, M. Angelis, M. Rosemann, 2010, Mammalian Genome.