Kazuhiko Yamada

D. Sachs, J. Madsen, S. Houser, 2004, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

The Role of Regulatory Cells in Miniature Swine Rendered Tolerant to Cardiac Allografts by Donor Kidney Cotransplantation

D. Sachs, J. Madsen, Kazuhiko Yamada, 2003, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Protection of Pancreatic Islets Using Theranostic Silencing Nanoparticles in a Baboon Model of Islet Transplantation

A. Moore, Y. Ariyoshi, Ping Wang, 2020, Diabetes.

α1,3-Galactosyltransferase Gene-Knockout Pig Heart Transplantation in Baboons with Survival Approaching 6 Months

D. Sachs, K. Kuwaki, S. Robson, 2005, Transplantation.

Pig islet xenograft rejection in a mouse model with an established human immune system

G. Weir, Shumei Wang, Yong-Guang Yang, 2008, Xenotransplantation.

Immunomodulatory activity of lenvatinib contributes to antitumor activity in the Hepa1‐6 hepatocellular carcinoma model

Y. Funahashi, J. Matsui, Yu Kato, 2018, Cancer science.

The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of xenocorneal transplantation

R. Pierson, Y. Takeuchi, L. Scobie, 2014, Xenotransplantation.

Transgenic expression of human CD47 reduces phagocytosis of porcine endothelial cells and podocytes by baboon and human macrophages

D. Sachs, M. Sykes, D. Ayares, 2019, Xenotransplantation.

GalT‐KO pig lungs are highly susceptible to acute vascular rejection in baboons, which may be mitigated by transgenic expression of hCD47 on porcine blood vessels

T. Nagayasu, D. Sachs, M. Sykes, 2018, Xenotransplantation.

Tolerance in xenotransplantation

D. Sachs, M. Sykes, Kazuhiko Yamada, 2007, Current opinion in organ transplantation.

T‐cell‐mediated immunological barriers to xenotransplantation

S. Robson, J. Scalea, Kazuhiko Yamada, 2012, Xenotransplantation.

Peroxisome proliferator‐activated receptor δ as a molecular target to regulate lung cancer cell growth

Y. Yano, T. Yano, H. Hagiwara, 2005 .

Absence of Replication of Porcine Endogenous Retrovirus and Porcine Lymphotropic Herpesvirus Type 1 with Prolonged Pig Cell Microchimerism after Pig-to-Baboon Xenotransplantation

D. Sachs, D. Cooper, A. Griesemer, 2008, Journal of Virology.

Effect of acerola cherry extract on cell proliferation and activation of ras signal pathway at the promotion stage of lung tumorigenesis in mice.

I. Nagamine, H. Sakurai, T. Yano, 2002, Journal of nutritional science and vitaminology.

Catechin and caffeine contents in green tea at different harvest periods and their metabolism in miniature swine

Kazuhiko Yamada, H. Sahara, Y. Minami, 2019, Food science & nutrition.

Regulatory T cells generated by the kidney may mediate the beneficial immune effects of combining kidneywith heart transplantation

D. Sachs, J. Madsen, Kazuhiko Yamada, 2004 .

Down-regulation of p27Kip1 Promotes Cell Proliferation of Rat Neonatal Cardiomyocytes Induced by Nuclear Expression of Cyclin D1 and CDK4

K. Nakayama, T. Kamura, S. Ogawa, 2004, Journal of Biological Chemistry.

Strain and Age-Related Changes in the Localization of Intestinal CD161+ Natural Killer Cells and CD8+ Intraepithelial Lymphocytes along the Longitudinal Crypt Axis in Inbred Rats

S. Ishizuka, H. Hara, Hong-lin Xu, 2005, Bioscience, biotechnology, and biochemistry.

Relationship between formation of aberrant crypts and acute responses of colonic epithelial cells to genotoxic treatment among inbred rat strains.

S. Ishizuka, A. Takeuchi, Kazuhiko Yamada, 2003, Cancer letters.

ROLE OF THE THYMUS IN TRANSPLANTATION TOLERANCE IN MINIATURE SWINE: IV. THE THYMUS IS REQUIRED DURING THE INDUCTION PHASE, BUT NOT THE MAINTENANCE PHASE, OF RENAL ALLOGRAFT TOLERANCE1

D. Sachs, P. Gianello, F. Ierino, 2004, Transplantation.

Role of the Thymus in Transplantation Tolerance in Miniature Swine. I. Requirement of the Thymus for Rapid and Stable Induction of Tolerance to Class I–mismatched Renal Allografts

R. Colvin, D. Sachs, P. Gianello, 1997, The Journal of experimental medicine.

Antidonor CTL Reactivity Lymphocytes from Tolerant Swine Inhibit Antigen-Activated Peripheral Blood Renal Allografts in Miniature Swine : Donor Peripheral Tolerance to Class I Mismatched

D. Sachs, F. Ierino, Kazuhiko Yamada, 1998 .

Effect of the Diabetic State on Islet Engraftment and Function in a Large Animal Model of Islet–Kidney Transplantation

D. Sachs, A. Griesemer, A. Shimizu, 2017, Cell transplantation.

Intra-bone Bone Marrow Transplantation in Pig-to-Nonhuman Primates for the Induction of Tolerance Across Xenogeneic Barriers.

Y. Ariyoshi, Kazuhiko Yamada, Thomas Pomposelli, 2020, Methods in molecular biology.

Xenotransplantation: immunological hurdles and progress toward tolerance

M. Sykes, A. Griesemer, Kazuhiko Yamada, 2014, Immunological reviews.

Achieving tolerance in pig-to-primate xenotransplantation: reality or fantasy.

D. Sachs, M. Sykes, Kazuhiko Yamada, 2009, Transplant immunology.

Vascularized islet-cell transplantation in miniature swine. I. Preparation of vascularized islet kidneys

D. Sachs, H. Kitamura, J. O'neil, 2002, Transplantation.

Xenogeneic thymus transplantation in a pig-to-baboon model1

R. Colvin, J. Wain, D. Sachs, 2003, Transplantation.

Bone marrow is a source of regenerated cardiomyocytes in doxorubicin-induced cardiomyopathy and granulocyte colony-stimulating factor enhances migration of bone marrow cells and attenuates cardiotoxicity of doxorubicin under electron microscopy.

S. Kitamura, S. Fukuhara, S. Tomita, 2004, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Bone marrow mononuclear cell transplantation had beneficial effects on doxorubicin-induced cardiomyopathy.

M. Hamamoto, S. Kitamura, S. Fukuhara, 2004, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Xenograft Tolerance and Immune Function of Human T Cells Developing in Pig Thymus Xenografts

M. Sykes, H. Kalscheuer, Kazuhiko Yamada, 2014, The Journal of Immunology.

Role of Persistence of Antigen and Indirect Recognition in the Maintenance of Tolerance to Renal Allografts

D. Sachs, P. Gianello, A. Griesemer, 2008, Transplantation.

Vascularized composite islet-kidney transplantation in a miniature swine model

D. Sachs, A. Griesemer, Kazuhiko Yamada, 2007, Cell Biochemistry and Biophysics.

Indirect recognition of allopeptides promotes the development of cardiac allograft vasculopathy

J. Madsen, M. Sayegh, S. Houser, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Blockade of CD28-B7, But Not CD40-CD154, Prevents Costimulation of Allogeneic Porcine and Xenogeneic Human Anti-Porcine T Cell Responses1

D. Sachs, J. Madsen, M. Sayegh, 2000, The Journal of Immunology.

Responses and Xenogeneic Human Anti-Porcine T Cell Prevents Costimulation of Allogeneic Porcine Blockade of CD28-B7, But Not CD40-CD154,

D. Sachs, J. Madsen, M. Sayegh, 2000 .

Xenogeneic Human Anti-Porcine T Cell Prevents Costimulation of Allogeneic Porcine Blockade of CD 28B 7 , But Not CD 40-CD 154 ,

D. Sachs, J. Madsen, M. Sayegh, 2000 .

Role of the Thymus and Kidney Graft in the Maintenance of Tolerance to Heart Grafts in Miniature Swine

D. Sachs, J. Madsen, S. Houser, 2005, Transplantation.

Vascularized Composite Allograft Transplant Survival in Miniature Swine: Is MHC Tolerance Sufficient for Acceptance of Epidermis?

C. Cetrulo, D. Leonard, D. Sachs, 2013, Transplantation.

Peroxisome proliferator-activated receptor delta as a molecular target to regulate lung cancer cell growth.

Y. Yano, T. Yano, H. Hagiwara, 2005, FEBS letters.

Linked Suppression across an MHC-Mismatched Barrier in a Miniature Swine Kidney Transplantation Model1

D. Sachs, A. Griesemer, M. Okumi, 2006, The Journal of Immunology.

Porcine Cytomegalovirus Infection Is Associated With Early Rejection of Kidney Grafts in a Pig to Baboon Xenotransplantation Model

D. Sachs, R. Wilkinson, J. Fishman, 2014, Transplantation.

Current progress in xenogeneic tolerance

J. Scalea, Kazuhiko Yamada, 2012, Current opinion in organ transplantation.

Effective long-term immunosuppression in rats by subcutaneously implanted sustained-release tacrolimus pellet: Effect on spinally grafted human neural precursor survival

F. Rypáček, M. Hefferan, M. Marsala, 2013, Experimental Neurology.

Antibody reactivity with new antigens revealed in multi‐transgenic triple knockout pigs may cause early loss of pig kidneys in baboons

D. Sachs, M. Sykes, D. Ayares, 2020, Xenotransplantation.

Class I Barrier in Swine Thymic Transplantation Across an MHC

R. Colvin, D. Sachs, M. Sykes, 1999 .

Pigs as xenogeneic donors

A. Griesemer, M. Okumi, Kazuhiko Yamada, 2005 .

Allosensitization Does Not Increase the Risk of Xenoreactivity to α1,3-Galactosyltransferase Gene-Knockout Miniature Swine in Patients on Transplantation Waiting Lists

S. Saidman, D. Sachs, D. Cooper, 2006, Transplantation.

Progress in islet xenotransplantation: Immunologic barriers, advances in gene editing, and tolerance induction strategies for xenogeneic islets in pig-to-primate transplantation

Yu Hisadome, Kazuhiko Yamada, Daniel L. Eisenson, 2022, Frontiers in Transplantation.

Prolonged survival of GalT‐KO swine skin on baboons

D. Sachs, A. Shimizu, Kazuhiko Yamada, 2010, Xenotransplantation.

Preparation of hybrid porcine thymus containing non‐human primate thymic epithelial cells in miniature swine

M. Sykes, Y. Ariyoshi, A. Shimizu, 2019, Xenotransplantation.

Occurrence of specific humoral non‐responsiveness to swine antigens following administration of GalT‐KO bone marrow to baboons

D. Sachs, M. Sykes, A. Griesemer, 2010, Xenotransplantation.

Intra‐bone bone marrow transplantation from hCD47 transgenic pigs to baboons prolongs chimerism to >60 days and promotes increased porcine lung transplant survival

D. Sachs, M. Sykes, D. Ayares, 2019, Xenotransplantation.

Reversal of age-related thymic involution by an LHRH agonist in miniature swine.

D. Sachs, A. Griesemer, M. Okumi, 2010, Transplant immunology.

Variable relationship between chimerism and tolerance after hematopoietic cell transplantation without myelosuppressive conditioning1

D. Sachs, D. Neville, Y. Fuchimoto, 2002, Transplantation.

Model Tolerance in a Kidney Transplantation Relationship Between Chimerism and

D. Sachs, Y. Fuchimoto, A. Shimizu, 1999 .

Progress in Xenotransplantation: Immunologic Barriers, Advances in Gene Editing, and Successful Tolerance Induction Strategies in Pig-To-Primate Transplantation

Yu Hisadome, Kazuhiko Yamada, Daniel L. Eisenson, 2022, Frontiers in Immunology.

Tolerogenicity of Donor Major Histocompatibility Complex–Matched Skin Grafts in Previously Tolerant Massachusetts General Hospital Miniature Swine

D. Sachs, A. Griesemer, J. Scalea, 2012, Transplantation.

Role of the Thymus in Transplantation Tolerance in Miniature Swine: V. Deficiency of the Graft-to-Thymus Pathway of Tolerance Induction in Recipients of Cardiac Transplants

D. Sachs, S. Houser, M. Okumi, 2006, Transplantation.

Vascularized thymic lobe transplantation in miniature swine: thymopoiesis and tolerance induction across fully MHC-mismatched barriers.

D. Sachs, R. Barth, J. LaMattina, 2004, Proceedings of the National Academy of Sciences of the United States of America.

&agr;1,3-Galactosyltransferase Gene-Knockout Miniature Swine Produce Natural Cytotoxic Anti-Gal Antibodies

D. Sachs, R. Hawley, D. Cooper, 2004, Transplantation.

Protective Effect of Neutralization of the Extracellular High-Mobility Group Box 1 on Renal Ischemia-Reperfusion Injury in Miniature Swine

E. Clayman, A. Shimizu, Kazuhiko Yamada, 2014, Transplantation.

Vascularized islet cell transplantation in miniature Swine: islet-kidney allografts correct the diabetic hyperglycemia induced by total pancreatectomy.

D. Sachs, J. O'neil, R. Barth, 2002, Diabetes.

Differential regulation of cyclin D1 and D2 in protecting against cardiomyocyte proliferation

Kazuhiko Yamada, S. Kitajima, M. Tamamori‐Adachi, 2008, Cell cycle.

Expression of human CD47 in pig glomeruli prevents proteinuria and prolongs graft survival following pig‐to‐baboon xenotransplantation

D. Sachs, M. Sykes, D. Amarnath, 2021, Xenotransplantation.

Xenogeneic thymokidney and thymic tissue transplantation in a pig-to-baboon model: I. evidence for pig-specific T-cell unresponsiveness1

R. Colvin, D. Sachs, M. Sykes, 2003, Transplantation.

of Composite Thymokidneys to Transplantation II. Induction of Tolerance by Thymic Transplantation in Miniature Swine.

R. Colvin, D. Sachs, A. Shimizu, 2013 .

Thymic transplantation in miniature swine: III. induction of tolerance by transplantation of composite thymokidneys across fully major histocompatibility complex-mismatched barriers

D. Sachs, H. Kitamura, R. Barth, 2003, Transplantation.

Vascularized thymic lobe transplantation in miniature swine: I. Vascularized thymic lobe allografts support thymopoiesis1

D. Sachs, H. Kitamura, R. Barth, 2002, Transplantation.

Inducing Tolerance by Thymus Transplantation

D. Sachs, R. Barth, Kazuhiko Yamada, 2001 .

THYMIC TRANSPLANTATION IN MINIATURE SWINE

R. Colvin, D. Sachs, F. Ierino, 1999 .

Advances in xenotransplantation: is the Gal knockout pig essential to clinical success?

M. Sykes, Kazuhiko Yamada, 2007 .

Upregulation of CD80 on glomerular podocytes plays an important role in development of proteinuria following pig‐to‐baboon xeno‐renal transplantation – an experimental study

M. Lanaspa, C. Rivard, D. Sachs, 2018, Transplant international : official journal of the European Society for Organ Transplantation.

Assessing the Effect of Immunosuppression on Engraftment of Pancreatic Islets

D. Sachs, M. Okumi, A. Shimizu, 2013, Transplantation.

First Experience With the Use of a Recombinant CD3 Immunotoxin as Induction Therapy in Pig-to-Primate Xenotransplantation: The Effect of T-Cell Depletion on Outcome

D. Sachs, J. Scalea, A. Shimizu, 2011, Transplantation.

Quantification of Baboon Thymopoiesis in Porcine Thymokidney Xenografts by the Signal-Joining T-Cell Receptor Excision Circle Assay

D. Sachs, R. Hawley, A. Griesemer, 2011, Transplantation.

XENOGENEIC THYMUS TRANSPLANTATION IN A PIG-TO-

R. Colvin, J. Wain, D. Sachs, 2003 .

Xenogeneic thymic replacement to achieve immune restoration in HIV infection

R. Johnson, D. Sachs, M. Sykes, 2003 .

GalT-KO pigs: is the cup half empty or half full?

R. Colvin, D. Sachs, M. Sykes, 2007, Transplantation.

INDUCTION OF TRANSPLANTATION TOLERANCE WITH A SHORT COURSE OF TACROLIMUS(FK506): I. Rapid and Stable Tolerance to Two-Haplotype Fully MHC-Mismatched Kidney Allografts in Miniature Swine 1

H. Kitamura, R. Barth, J. LaMattina, 2001, Transplantation.

RAPID COMMUNICATION INDUCTION OF TRANSPLANTATION TOLERANCE WITH A SHORT COURSE OF TACROLIMUS (FK506)

D. Sachs, H. Kitamura, R. Barth, 2001 .

Vascularized Thymic Lobe Transplantation in a Pig-to-Baboon Model: A Novel Strategy for Xenogeneic Tolerance Induction and T-cell Reconstitution

D. Sachs, D. Neville, M. Sykes, 2005, Transplantation.

Pathologic characteristics of transplanted kidney xenografts.

R. Colvin, D. Sachs, S. Robson, 2012, Journal of the American Society of Nephrology : JASN.

Cardiovascular , Pulmonary and Renal Pathology Thrombotic Microangiopathy Associated with Humoral Rejection of Cardiac Xenografts from 1 , 3-Galactosyltransferase Gene-Knockout Pigs in Baboons

R. Colvin, D. Sachs, K. Kuwaki, 2010 .

GalT knockout pig to baboon xenotransplantation

D. Sachs, Kazuhiko Yamada, 2006 .

Localization of Ca2+ binding proteins in lymphatic tissues.

M. Yamakawa, T. Tsunoda, T. Ogata, 1995 .

Thrombotic microangiopathic glomerulopathy in human decay accelerating factor-transgenic swine-to-baboon kidney xenografts.

R. Colvin, D. Sachs, J. LaVelle, 2005, Journal of the American Society of Nephrology : JASN.

Leukocytapheresis therapy, performed with leukocyte removal filter, for inflammatory bowel disease

K. Amano, T. Shimoyama, Kazuhiko Yamada, 1995, Journal of Gastroenterology.

Rituximab treatment prevents the early development of proteinuria following pig-to-baboon xeno-kidney transplantation.

A. Shimizu, Kazuhiko Yamada, M. Tasaki, 2014, Journal of the American Society of Nephrology : JASN.

Transcriptional Coactivator p300/CBP-Associated Factor and p300/CBP-Associated Factor Type B Are Required for Normal Estrogen Response of the Mouse Uterus

J. Yamauchi, Kazuhiko Yamada, M. Hanai, 2004, Bioscience, biotechnology, and biochemistry.

Co-transplantation of Vascularized Thymic Graft with Kidney in Pig-to-Nonhuman Primates for the Induction of Tolerance Across Xenogeneic Barriers.

Y. Ariyoshi, Kazuhiko Yamada, M. Sekijima, 2020, Methods in molecular biology.

Towards human organ generation using interspecies blastocyst complementation: Challenges and perspectives for therapy

Munemasa Mori, Kazuhiko Yamada, A. Miura, 2023, Frontiers in Cell and Developmental Biology.

Intestinal Mucormycosis in a Hemodialysis Patient Treated with Desferrioxamine

Kazuhiko Yamada, T. Kaneko, M. Hotchi, 1991, Acta pathologica japonica.

Xenotransplantation: Where Are We with Potential Kidney Recipients? Recent Progress and Potential Future Clinical Trials

M. Lanaspa, Richard J. Johnson, Kazuhiko Yamada, 2017, Current Transplantation Reports.

Activation of Cytomegalovirus in Pig-to-Primate Organ Xenotransplantation

David K. C. Cooper, Amitinder Kaur, N. Mueller, 2002, Journal of Virology.

Lenvatinib plus anti-PD-1 antibody combination treatment activates CD8+ T cells through reduction of tumor-associated macrophage and activation of the interferon pathway

H. Kitano, Samik Ghosh, Ayako Yachie-Kinoshita, 2019, PloS one.

α-Fetoprotein Producing Undifferentiated Carcinoma of the Bladder

Kazuhiko Yamada, Y. Fujioka, M. Akimoto, 1994 .

Upregulation of CD59: Potential Mechanism of Accommodation in a Large Animal Model

A. Griesemer, M. Okumi, A. Shimizu, 2009, Transplantation.

Long-Term Acceptance of Fully Allogeneic Cardiac Grafts by Cotransplantation of Vascularized Thymus in Miniature Swine

D. Sachs, S. Houser, M. Okumi, 2006, Transplantation.

Systems Analysis of ATF3 in Stress Response and Cancer Reveals Opposing Effects on Pro-Apoptotic Genes in p53 Pathway

J. Miyoshi, Hiroshi Tanaka, Kazuhiko Yamada, 2011, PloS one.

Survival of syngeneic and allogeneic iPSC–derived neural precursors after spinal grafting in minipigs

Shawn P. Driscoll, F. Gage, A. Muotri, 2018, Science Translational Medicine.

Differential usage of alternate promoters of the human stress response gene ATF3 in stress response and cancer cells

Toshiki Watanabe, Masashi Watanabe, Qin Liu, 2009, Nucleic acids research.

Cytoplasmic Inheritance of Transplantation Antigens in Animals Produced by Nuclear Transfer

D. Sachs, M. Okumi, Kazuhiko Yamada, 2009, Transplantation.

Absence of interaction between porcine endogenous retrovirus and porcine cytomegalovirus in pig‐to‐baboon renal xenotransplantation in vivo

D. Sachs, R. Wilkinson, J. Fishman, 2018, Xenotransplantation.

Meeting Report: The Fifth International Samuel Strober Workshop on Clinical Immune Tolerance

J. Mathew, J. Levitsky, M. Mapara, 2023, Transplantation.

Development of Antidonor Antibody Directed Toward Non–Major Histocompatibility Complex Antigens in Tolerant Animals

D. Sachs, P. Gianello, J. Scalea, 2014, Transplantation.

Activation of porcine cytomegalovirus, but not porcine lymphotropic herpesvirus, in pig-to-baboon xenotransplantation.

N. Mueller, D. Sachs, D. Cooper, 2004, The Journal of infectious diseases.

Reduced Efficacy of Ganciclovir Against Porcine and Baboon Cytomegalovirus in Pig‐to‐Baboon Xenotransplantation

N. Mueller, D. Sachs, D. Cooper, 2003, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Signal Joint T-Cell Receptor Excision Circle Assay in Miniature Swine

D. Sachs, Kazuhiko Yamada, P. Vallabhajosyula, 2011, Transplantation.

Hepatocyte Growth Factor Sustains T Regulatory Cells and Prolongs the Survival of Kidney Allografts in Major Histocompatibility Complex-Inbred CLAWN-Miniature Swine

D. Sachs, A. Ido, H. Tsubouchi, 2012, Transplantation.

Mechanisms of Tolerance: Role of the Thymus and Persistence of Antigen in Calcineurin-Induced Tolerance of Renal Allografts in MGH Miniature Swine

J. Scalea, Kazuhiko Yamada, I. Hanekamp, 2011 .

Tolerance and Long-Lasting Peripheral Chimerism After Allogeneic Intestinal Transplantation in MGH Miniature Swine

A. Griesemer, A. Shimizu, Kazuhiko Yamada, 2010, Transplantation.

Porcine CFSE mixed lymphocyte reaction and PKH-26 cell-mediated lympholysis assays.

A. Griesemer, M. Okumi, Kazuhiko Yamada, 2008, Transplant immunology.

Long-Term Acceptance of Renal Allografts following Prenatal Inoculation with Adult Bone Marrow

D. Sachs, W. Lee, D. Mathes, 2005, Transplantation.

Xenotransplantation and Kidney Regenerative Technology

Kazuhiko Yamada, M. Tasaki, J. Shah, 2017 .

Induction of cytotoxicity in human lung adenocarcinoma cells by 6‐O‐carboxypropyl‐α‐tocotrienol, a redox‐silent derivative of α‐tocotrienol

Y. Yano, T. Yano, Kazuhiko Yamada, 2005 .

Thymic Transplantation in Miniature Swine. II. Induction of Tolerance by Transplantation of Composite Thymokidneys to Thymectomized Recipients1

R. Colvin, D. Sachs, F. Ierino, 2000, The Journal of Immunology.

Remaining Physiological Barriers in Porcine Kidney Xenotransplantation: Potential Pathways behind Proteinuria as well as Factors Related to Growth Discrepancies following Pig-to-Kidney Xenotransplantation

M. Lanaspa, Richard J. Johnson, Kazuhiko Yamada, 2018, Journal of immunology research.

The Protective Effects of Carbon Monoxide Against Hepatic Warm Ischemia–Reperfusion Injury in MHC-Inbred Miniature Swine

A. Shimizu, Kazuhiko Yamada, H. Sahara, 2019, Journal of Gastrointestinal Surgery.

Immunomodulatory Strategies Directed Toward Tolerance of Vascularized Composite Allografts

C. Cetrulo, D. Leonard, R. Colvin, 2015, Transplantation.

E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling

T. Owa, H. Kouji, Yuji Yamamoto, 2021, Cancer Research.

Detection of regulatory cells as an assay for allograft tolerance in miniature swine.

D. Sachs, C. Baron, D. Mathes, 2004, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Regulatory mechanism of peripheral tolerance: in vitro evidence for dominant suppression of host responses during the maintenance phase of tolerance to renal allografts in miniature swine.

D. Sachs, F. Ierino, Kazuhiko Yamada, 2003, Transplant immunology.

Induction of tolerance to heart transplants by simultaneous cotransplantation of donor kidneys may depend on a radiation-sensitive renal-cell population

D. Sachs, J. Madsen, S. Houser, 2003, Transplantation.

Degradation of p21Cip1 through Anaphase-promoting Complex/Cyclosome and Its Activator Cdc20 (APC/CCdc20) Ubiquitin Ligase Complex-mediated Ubiquitylation Is Inhibited by Cyclin-dependent Kinase 2 in Cardiomyocytes*

T. Aso, T. Yasukawa, T. Okazaki, 2011, The Journal of Biological Chemistry.

Expression patterns of connexin 26 and connexin 43 mRNA in canine benign and malignant mammary tumours.

T. Yano, H. Hagiwara, Kazuhiko Yamada, 2006, Veterinary journal.

The rejuvenating effects of leuprolide acetate on the aged baboon's thymus.

D. Sachs, J. Scalea, A. Shimizu, 2014, Transplant immunology.

Pathology of renal xenograft rejection in pig to non‐human primate transplantation

A. Shimizu, Kazuhiko Yamada, 2006, Clinical transplantation.

Production of cloned NIBS (Nippon Institute for Biological Science) and α‐1, 3‐galactosyltransferase knockout MGH miniature pigs by somatic cell nuclear transfer using the NIBS breed as surrogates

T. Nunoya, D. Sachs, A. Shimizu, 2013, Xenotransplantation.

Thymic rejuvenation and the induction of tolerance by adult thymic grafts

Akira Shimizu, D. Sachs, A. Griesemer, 2006, Proceedings of the National Academy of Sciences.

Hydrogen sulfide prevents renal ischemia-reperfusion injury in CLAWN miniature swine.

Y. Ariyoshi, Kazuhiko Yamada, H. Sahara, 2017, The Journal of surgical research.

Thymic transplantation in pig-to-nonhuman primates for the induction of tolerance across xenogeneic barriers.

J. Scalea, Kazuhiko Yamada, 2012, Methods in molecular biology.

Beneficial Effects of Perioperative Low-Dose Inhaled Carbon Monoxide on Pulmonary Allograft Survival in MHC-Inbred CLAWN Miniature Swine

H. Wada, H. Date, J. Scalea, 2010, Transplantation.

Histopathology of xenografts in pig to non‐human primate discordant xenotransplantation

A. Shimizu, Kazuhiko Yamada, 2010, Clinical transplantation.

Human anti‐pig T‐cell mediated cytotoxicity

D. Sachs, Kazuhiko Yamada, J. Seebach, 1996 .

(2) Cotransplantation of vascularized thymus and kidney from GalT‐KO pigs to baboons

D. Sachs, M. Sykes, A. Griesemer, 2007 .

Pig-to-nonhuman primate organ xenotransplantation

D. Sachs, D. Cooper, M. Ezzelarab, 2005 .

Induction of cytotoxicity in human lung adenocarcinoma cells by 6-O-carboxypropyl-alpha-tocotrienol, a redox-silent derivative of alpha-tocotrienol.

Y. Yano, T. Yano, Kazuhiko Yamada, 2005, International Journal of Cancer.

The expression of cytokines and their receptors in lymphoid tissues.

M. Yamakawa, T. Tsunoda, T. Ogata, 1995 .

Cardiomyocyte proliferation and protection against post-myocardial infarction heart failure by cyclin D1 and Skp2 ubiquitin ligase.

K. Nakayama, M. Isobe, Y. Maejima, 2008, Cardiovascular research.

T‐cell differentiation of human and  non‐human primate CD34+ hematopoietic progenitor cells using porcine thymic stroma

R. Johnson, M. Rosenzweig, K. Yamada, 2001, Xenotransplantation.

A Strategy to Simultaneously Cure Type 1 Diabetes and Diabetic Nephropathy by Transplant of Composite Islet-Kidney Grafts

Ping Wang, Kazuhiko Yamada, Thomas Pomposelli, 2021, Frontiers in Endocrinology.

Carbon monoxide reduces pulmonary ischemia-reperfusion injury in miniature swine.

Akira Shimizu, M. Okumi, A. Shimizu, 2010, The Journal of thoracic and cardiovascular surgery.

Monitoring of Allogeneic Islet Grafts in Nonhuman Primates Using MRI

Anna Moore, Christian Schuetz, Lingling Wei, 2015, Transplantation.

Role of Intrinsic Factors in the Growth of Transplanted Organs Following Transplantation.

Kazuhiko Yamada, T. Tanabe, J. Shah, 2017, Journal of immunobiology.

Editorial: Xenotransplantation for the therapy of diabetes: A new look

R. Bottino, Kazuhiko Yamada, 2023, Frontiers in Endocrinology.

Role of Intrinsic (Graft) Versus Extrinsic (Host) Factors in the Growth of Transplanted Organs Following Allogeneic and Xenogeneic Transplantation

D. Sachs, A. Shimizu, A. Shimizu, 2017, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Medical Gas (Carbon Monoxide, Hydrogen Sulfide) Therapy Prolongs Survival of the Fully MHC-Disparate Lung Graft From Brain-Dead Donors in Miniature Swine

Kazuhiko Yamada, H. Sahara, 2014 .

Rejection of Cardiac Xenografts Transplanted from α1,3‐Galactosyltransferase Gene‐Knockout (GalT‐KO) Pigs to Baboons

D. Sachs, K. Kuwaki, S. Robson, 2008, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

The Induction of Tolerance of Renal Allografts by Adoptive Transfer in Miniature Swine

D. Sachs, M. Okumi, A. Shimizu, 2013, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

ROLE OF THE THYMUS IN TRANSPLANTATION TOLERANCE IN MINIATURE SWINE: IV. THE THYMUS IS REQUIRED DURING THE INDUCTION PHASE, BUT NOT THE MAINTENANCE PHASE, OF RENAL ALLOGRAFT TOLERANCE1

R. Hetzer, M. Loebe, E. Potapov, 2004, Transplantation.

Pig kidney transplantation in baboons: anti-Gal(alpha)1-3Gal IgM alone is associated with acute humoral xenograft rejection and disseminated intravascular coagulation.

R. Colvin, D. Sachs, S. Robson, 2001, Transplantation.

Abrogation of Renal Allograft Tolerance in MGH Miniature Swine: The Role of Intra‐Graft and Peripheral Factors in Long‐Term Tolerance

A. Shimizu, Kazuhiko Yamada, C. Leguern, 2014, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Results of Gal‐Knockout Porcine Thymokidney Xenografts

D. Sachs, M. Sykes, S. Robson, 2009, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

T‐cell‐mediated immunological barriers to xenotransplantation

S. Robson, J. Scalea, Kazuhiko Yamada, 2012, Xenotransplantation.

High Incidence of Xenogenic Bone Marrow Engraftment in Pig‐to‐Baboon Intra‐Bone Bone Marrow Transplantation

I. Wamala, D. Sachs, E. Clayman, 2015, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Occurrence of specific humoral non‐responsiveness to swine antigens following administration of GalT‐KO bone marrow to baboons

D. Sachs, M. Sykes, A. Griesemer, 2010, Xenotransplantation.

Porcine kidney and heart transplantation in baboons undergoing a tolerance induction regimen and antibody adsorption.

R. Colvin, D. Sachs, A. Cosimi, 1999, Transplantation.

Potential of aspirin to inhibit thrombotic microangiopathy in alpha1,3-galactosyltransferase gene-knockout pig hearts after transplantation in baboons.

D. Sachs, K. Kuwaki, S. Robson, 2005, Transplantation proceedings.

Bortezomib, C1‐Inhibitor and Plasma Exchange Do Not Prolong the Survival of Multi‐Transgenic GalT‐KO Pig Kidney Xenografts in Baboons

Y. Takeuchi, L. Scobie, M. Daha, 2015, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Bone marrow transplantation from α1,3‐galactosyltransferase gene‐knockout pigs in baboons

M. Denaro, D. Sachs, K. Kuwaki, 2004, Xenotransplantation.

Predictors of Organ Allograft Tolerance Following Hematopoietic Cell Transplantation

D. Sachs, K. Yamada, Kazuhiko Yamada, 2006, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

The effects of brain death and ischemia on tolerance induction are organ‐specific

R. Colvin, G. LaMuraglia, D. Sachs, 2018, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Role of Bone Marrow Maturity, Insulin‐Like Growth Factor 1 Receptor, and Forkhead Box Protein N1 in Thymic Involution and Rejuvenation

A. Shimizu, K. Yamada, Kazuhiko Yamada, 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

IL-2 PRODUCTION INHIBITORY ACTIVITY OF THE SERA IN TRYPANOSOMA BRUCEI GAMBIENSE INFECTED MICE

T. Komatsu, Kazuhiko Yamada, S. Shinka, 1989 .

Induction of tolerance to renal allografts across single-haplotype MHC disparities in miniature swine.

Kazuhiko Yamada, J. Fishbein, D. Vitiello, 1995, Transplantation.

Mixed chimerism and tolerance without whole body irradiation in a large animal model.

R. Colvin, D. Sachs, D. Neville, 2000, The Journal of clinical investigation.

Role of the thymus in transplantation tolerance in miniature swine. III. Surgical manipulation of the thymus interferes with stable induction of tolerance to class I-mismatched renal allografts.

R. Colvin, D. Sachs, P. Gianello, 1999, Transplantation.

Mechanisms of Tolerance: Role of the Thymus and Persistence of Antigen in Calcineurin-Induced Tolerance of Renal Allografts in MGH Miniature Swine

J. Scalea, Kazuhiko Yamada, I. Hanekamp, 2011 .

Role of Persistence of Antigen and Indirect Recognition in the Maintenance of Tolerance to Renal Allografts

D. Sachs, P. Gianello, A. Griesemer, 2008, Transplantation.

Role of the thymus in transplantation tolerance in miniature swine: II. Effect of steroids and age on the induction of tolerance to class I mismatched renal allografts.

R. Colvin, D. Sachs, P. Gianello, 1999, Transplantation.

Tolerogenicity of Donor Major Histocompatibility Complex–Matched Skin Grafts in Previously Tolerant Massachusetts General Hospital Miniature Swine

D. Sachs, A. Griesemer, J. Scalea, 2012, Transplantation.

Carbon monoxide reduces pulmonary ischemia-reperfusion injury in miniature swine.

M. Okumi, A. Shimizu, Kazuhiko Yamada, 2010, The Journal of thoracic and cardiovascular surgery.

Intragraft events preceding chronic renal allograft rejection in a modified tolerance protocol.

R. Colvin, D. Sachs, A. Shimizu, 2000, Kidney international.

Transplantation tolerance prevents cardiac allograft vasculopathy in major histocompatibility complex class I-disparate miniature swine.

D. Sachs, J. Madsen, M. Pins, 1998, Transplantation.

Mechanisms of tolerance induction and prevention of cardiac allograft vasculopathy in miniature swine: the effect of augmentation of donor antigen load.

D. Sachs, J. Madsen, H. Aretz, 2000, The Journal of thoracic and cardiovascular surgery.

Mechanism of tolerance to class I-mismatched renal allografts in miniature swine: regulation of interleukin-2 receptor alpha-chain expression on CD8 peripheral blood lymphocytes of tolerant animals.

D. Sachs, F. Ierino, T. Lorf, 1998, Transplantation.

Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha1,3-galactosyltransferase gene-knockout pigs in baboons.

Kazuhiko Yamada, Simon C. Robson, Henk-Jan Schuurman, 2008, The American journal of pathology.

Kidney‐Induced Cardiac Allograft Tolerance in Miniature Swine is Dependent on MHC‐Matching of Donor Cardiac and Renal Parenchyma

C. Cetrulo, D. Leonard, R. Colvin, 2015, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.