Hang-zi Chen

发表

Orphan receptor TR3 attenuates the p300-induced acetylation of retinoid X receptor-alpha.

Wen-xiu Zhao, M. Tian, Bi-xing Zhao, 2007, Molecular endocrinology.

A unique pharmacophore for activation of the nuclear orphan receptor Nur77 in vivo and in vitro.

Y. Wang, Juan Wang, Yan Chen, 2010, Cancer research.

Orphan receptor TR3 enhances p53 transactivation and represses DNA double-strand break repair in hepatoma cells under ionizing radiation.

Y. Wang, Jie Luo, Qiao Wu, 2011, Molecular Endocrinology.

Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis

Jiahuai Han, Dawang Zhou, Bo Zhou, 2018, Cell Research.

The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8

Dawang Zhou, Bo Zhou, Qiao Wu, 2021, Cell Research.

Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression

Xianming Deng, Qiao Wu, Tianwei Lin, 2020, Proceedings of the National Academy of Sciences.

Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity.

Y. Wang, Qiao Wu, Tianwei Lin, 2015, Chemistry & biology.

Enhancement of Hypothalamic STAT3 Acetylation by Nuclear Receptor Nur77 Dictates Leptin Sensitivity

Yan Chen, Qiao Wu, Qian Xiao, 2015, Diabetes.

Akt phosphorylates the TR3 orphan receptor and blocks its targeting to the mitochondria.

Bing Zhang, Wen-xiu Zhao, Bi-xing Zhao, 2008, Carcinogenesis.

The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling

Jiahuai Han, Y. Wang, Jie Luo, 2012, EMBO molecular medicine.

Negative regulation of transcription coactivator p300 by orphan receptor TR3

Jie Luo, Gui-deng Li, Hang-zi Chen, 2007, Nucleic acids research.

Orphan receptor TR3 participates in cisplatin-induced apoptosis via Chk2 phosphorylation to repress intestinal tumorigenesis.

Y. Wang, Qiao Wu, Hang-zi Chen, 2012, Carcinogenesis.

The orphan nuclear receptor TR3/Nur77 regulates ER stress and induces apoptosis via interaction with TRAPγ.

Qiao Wu, Hang-zi Chen, Wei-jia Wang, 2013, The international journal of biochemistry & cell biology.

A novel function of p53 in TR3-MDM2 cross-talk

Hang-zi Chen, Qiao Wu, 2007, Cell Research.

HK1 from hepatic stellate cell–derived extracellular vesicles promotes progression of hepatocellular carcinoma

Dawang Zhou, Tianwei Lin, Ya-ying Huang, 2022, Nature Metabolism.

Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor Microenvironment.

Dawang Zhou, Qiao Wu, Hang-zi Chen, 2020, Molecular cell.

Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation

Qiao Wu, S. Zhang, K. Chien, 2017, Nature Communications.

p53 mediates the negative regulation of MDM2 by orphan receptor TR3

Bi-xing Zhao, Gui-deng Li, Bo Liu, 2006, The EMBO journal.

The orphan receptor TR3 suppresses intestinal tumorigenesis in mice by downregulating Wnt signalling

Qiao Wu, Bo Liu, Hang-zi Chen, 2011, Gut.

A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis.

L. Hui, Xiaodong Wang, Qiao Wu, 2020, Cell reports.

Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway.

Jiahuai Han, Y. Wang, Yan Chen, 2014, Nature chemical biology.

Nuclear Receptor Nur77 Facilitates Melanoma Cell Survival under Metabolic Stress by Protecting Fatty Acid Oxidation.

Qiao Wu, K. Chien, Xiang Chen, 2018, Molecular cell.

Extracellular vesicles in the tumor immune microenvironment.

Hang-zi Chen, Pei-pei Hou, 2021, Cancer letters.

Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.

Jiahuai Han, Yan Chen, Qiao Wu, 2015, Nature chemical biology.

Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression.

A. Cowin, K. Chien, Hang-zi Chen, 2018, Cancer research.

Nur77-activated lncRNA WFDC21P attenuates hepatocarcinogenesis via modulating glycolysis

Qiao Wu, Hang-zi Chen, Y. Ai, 2020, Oncogene.

Regulation of the orphan receptor TR3 nuclear functions by c-Jun N terminal kinase phosphorylation.

Bo Liu, Hang-zi Chen, Qiao Wu, 2007, Endocrinology.

Therapeutic potency of compound RMY-205 for pulmonary fibrosis induced by SARS-CoV-2 nucleocapsid protein

Tianwei Lin, Hang-zi Chen, Baocan Wang, 2023, Cell Chemical Biology.

A feedback regulatory loop between methyltransferase PRMT1 and orphan receptor TR3

Y. Wang, Hang-zi Chen, Qiao Wu, 2008, Nucleic acids research.

Cytosporone B is an agonist for nuclear orphan receptor Nur77.

B. Weimer, Si-Yang Song, Sheng-Cai Lin, 2008, Nature chemical biology.

The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK.

Qiao Wu, Tianwei Lin, Yuan Wang, 2012, Nature chemical biology.

Orphan receptor TR3 is essential for the maintenance of stem-like properties in gastric cancer cells.

Hang-zi Chen, Jianchun Cai, Wei-jia Wang, 2013, Cancer letters.

Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P

F. Liu, Bo Zhou, Hang-zi Chen, 2023, Cell Research.

Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity.

Y. Wang, Qiao Wu, Tianwei Lin, 2015, Chemistry & biology.

Full-length GSDME mediates pyroptosis independent from cleavage.

Bo Zhou, Hang-zi Chen, Qi-tao Chen, 2024, Nature cell biology.