B. Hirakawa

发表

Intestinal Toxicity in Rats Following Administration of CDK4/6 Inhibitors Is Independent of Primary Pharmacology

Shuyan Lu, B. Jessen, Dalia Kalabat, 2018, Molecular Cancer Therapeutics.

Responses of the steroidogenic pathway from exposure to methyl-tert-butyl ether and tert-butanol.

E. Mihaich, B. Hirakawa, A. de Peyster, 2014, Toxicology.

Antisense Inhibition of S6 Kinase 1 Produces Improved Glucose Tolerance and Is Well Tolerated for 4 Weeks of Treatment in Rats

G. Alton, J. Heyen, B. Hirakawa, 2010, Pharmacology.

Characterization of IDN-6556 (3-{2-(2-tert-Butyl-phenylaminooxalyl)-amino]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic Acid): a Liver-Targeted Caspase Inhibitor

N. Hoglen, B. Hirakawa, C. Fisher, 2004, Journal of Pharmacology and Experimental Therapeutics.

Reversible lysine-targeted probes reveal residence time-based kinase selectivity

A. Burlingame, J. Taunton, J. Lapek, 2022, Nature Chemical Biology.

miR-208a as a Biomarker of Isoproterenol-induced Cardiac Injury in Sod2+/− and C57BL/6J Wild-type Mice

W. Evering, B. Hirakawa, G. Stevens, 2014, Toxicologic pathology.

Pan-FGFR inhibition leads to blockade of FGF23 signaling, soft tissue mineralization, and cardiovascular dysfunction.

E. Blasi, D. Trajkovic, B. Hirakawa, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

RTP801 gene expression is differentially upregulated in retinopathy and is silenced by PF-04523655, a 19-Mer siRNA directed against RTP801.

T. R. Johnson, P. Vicini, Dalia Kalabat, 2014, Investigative ophthalmology & visual science.

Reversible lysine-targeted probes reveal residence time-based kinase selectivity

A. Burlingame, J. Taunton, J. Lapek, 2022, Nature Chemical Biology.

A tyrosine kinase inhibitor‐induced myocardial degeneration in rats through off‐target phosphodiesterase inhibition

B. Jessen, Wenyue Hu, B. Hirakawa, 2012, Journal of applied toxicology : JAT.

First-in-class pan caspase inhibitor developed for the treatment of liver disease.

N. Chen, J. Díaz, K. Valentino, 2005, Journal of medicinal chemistry.

Characterization of the caspase inhibitor IDN-1965 in a model of apoptosis-associated liver injury.

K. Valentino, K. Tomaselli, A. Srinivasan, 2001, The Journal of pharmacology and experimental therapeutics.

Characterization of IDN-6556: a liver-targeted caspase inhibitor

N. Hoglen, B. Hirakawa, C. Fisher, 2004 .

Toxicogenomic Analysis of Cardiotoxicity in Rats

B. Jessen, B. Hirakawa, A. Peyster, 2008 .

Effect of the multitargeted tyrosine kinase inhibitors imatinib, dasatinib, sunitinib, and sorafenib on mitochondrial function in isolated rat heart mitochondria and H9c2 cells.

B. Jessen, L. Marroquin, J. Hynes, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Phenotypic Characterization of Targeted Knockdown of Cyclin-Dependent Kinases in the Intestinal Epithelial Cells.

Shuyan Lu, B. Jessen, Wenyue Hu, 2020, Toxicological sciences : an official journal of the Society of Toxicology.

Evaluation of JAK inhibition with topical tofacitinib in an experimental autoimmune uveitis model (EAU)

B. Hirakawa, Yi Zhang, Jing-Feng Huang, 2013 .

Dose-Related Gene Silencing of RTP801 With the siRNA PF04523655 in Long Evans Rat Models of STZ Induced Diabetes and Laser Induced CNV

T. R. Johnson, R. Schachar, A. Basile, 2010 .

Digoxin Is Not a Substrate for Organic Anion-Transporting Polypeptide Transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but Is a Substrate for a Sodium-Dependent Transporter Expressed in HEK293 Cells

Mitchell E Taub, Harma Ellens, Caroline A. Lee, 2011, Drug Metabolism and Disposition.

Running Title : Digoxin and OATP

Caroline A. Lee, H. Ellens, R. Sane, 2011 .