R. Jacobs

发表

Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell ‘stemness’ via the bone morphogenetic protein pathway

D. Hommes, H. Morreau, H. Verspaget, 2011, Gut.

A Meta-Analysis of SMAD4 Immunohistochemistry as a Prognostic Marker in Colorectal Cancer

J. Hardwick, P. W. Voorneveld, L. Kodach, 2015, Translational oncology.

Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK.

D. Hommes, J. Hoogenboom, H. Morreau, 2014, Gastroenterology.

The activities of Smad and Gli mediated signalling pathways in high-grade conventional osteosarcoma.

A. Cleton-Jansen, P. Hogendoorn, P. ten Dijke, 2012, European journal of cancer.

Key elements of the BMP/SMAD pathway co‐localize with CDX2 in intestinal metaplasia and regulate CDX2 expression in human gastric cell lines

G. R. van den Brink, I. van Seuningen, P. Paulo, 2008, The Journal of pathology.

Intestinal Tumorigenesis Is Not Affected by Progesterone Signaling in Rodent Models

D. Hommes, G. R. van den Brink, J. Heijmans, 2011, PloS one.

Statin Use After Diagnosis of Colon Cancer and Patient Survival.

R. Herings, P. Kuppen, C. V. D. van de Velde, 2017, Gastroenterology.

Evaluation of the prognostic value of pSMAD immunohistochemistry in colorectal cancer

H. Morreau, C. V. van Noesel, N. D. de Miranda, 2013, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer

D. Hommes, H. Verspaget, G. R. van den Brink, 2010, Carcinogenesis.

Patient Experiences and Outcomes of a Telehealth Clinical Care Pathway for Postoperative Inflammatory Bowel Disease Patients.

D. Hommes, R. Jacobs, A. Lightner, 2020, Telemedicine journal and e-health : the official journal of the American Telemedicine Association.

Healthy cotwins share gut microbiome signatures with their inflammatory bowel disease twins and unrelated patients.

Jingyuan Fu, A. Zhernakova, C. Wijmenga, 2021, Gastroenterology.

Cholesterol metabolism and colorectal cancers.

J. Hardwick, R. Jacobs, P. Voorneveld, 2012, Current opinion in pharmacology.

The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC

R. Tollenaar, D. Geraets, D. Hommes, 2014, British Journal of Cancer.

Reduced expression of bone morphogenetic protein receptor IA in pancreatic cancer is associated with a poor prognosis.

H. Morreau, S. Lam, K. Korkmaz, 2013, British journal of cancer.

Deficits in geriatric assessment associate with disease activity and -burden in older patients with inflammatory bowel disease.

F. V. van Deudekom, S. Mooijaart, P. Maljaars, 2021, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Kinome-wide analysis of the effect of statins in colorectal cancer

M. Peppelenbosch, J. Heijmans, M. Wildenberg, 2021, British Journal of Cancer.

The potential of statins for individualized colorectal cancer chemoprevention.

J. Hardwick, L. Kodach, R. Jacobs, 2011, Current drug targets.

Statin use is associated with a reduced incidence of colorectal cancer expressing SMAD4

H. Putter, R. Herings, H. Morreau, 2021, British Journal of Cancer.

Cholesterol metabolism and colorectal cancers.

J. Hardwick, R. Jacobs, P. Voorneveld, 2012, Current opinion in pharmacology.

Correction: Kinome-wide analysis of the effect of statins in colorectal cancer

M. Peppelenbosch, J. Heijmans, M. Wildenberg, 2021, British Journal of Cancer.

Deficits in geriatric assessment are important in relation to fatigue in older patients with Inflammatory Bowel Disease.

S. Mooijaart, A. van der Meulen-de Jong, R. Jacobs, 2024, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Frailty Screening is Associated with Hospitalization and Decline in Quality of Life and Functional Status in Older Patients with Inflammatory Bowel Disease

S. Mooijaart, A. van der Meulen-de Jong, R. Jacobs, 2023, Journal of Crohn's & colitis.