Y. Kanegae

发表

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

T. Noda, T. Akiyama, H. Shibata, 1997, Science.

BabA-mediated Adherence Is a Potentiator of the Helicobacter pylori Type IV Secretion System Activity*

C. Sasakawa, R. Haas, H. Mimuro, 2011, The Journal of Biological Chemistry.

Keratinocyte growth factor gene transduction ameliorates pulmonary fibrosis induced by bleomycin in mice.

K. Kurahashi, T. Goto, T. Yazawa, 2011, American journal of respiratory cell and molecular biology.

Keratinocyte growth factor gene transduction ameliorates acute lung injury and mortality in mice.

Yoshitsugu Yamada, K. Kurahashi, T. Goto, 2007, Human gene therapy.

Enhanced and specific gene expression via tissue-specific production of Cre recombinase using adenovirus vector.

S. Kaneko, H. Nakabayashi, T. Tamaoki, 1998, Biochemical and biophysical research communications.

Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability

T. Abe, Toru Suzuki, A. Yanagiya, 2020, RNA biology.

Establishment of a tamoxifen-inducible Cre-driver mouse strain for widespread and temporal genetic modification in adult mice

T. Ichise, N. Yoshida, Seiji Shiozawa, 2016, Experimental animals.

Simultaneous on/off regulation of transgenes located on a mammalian chromosome with Cre-expressing adenovirus and a mutant loxP.

Y. Kanegae, I. Saito, A. Okuda, 2003, Nucleic acids research.

Ligand-independent signaling by overexpressed CD30 drives NF-κB activation in Hodgkin–Reed-Sternberg cells

Shigeo Mori, Toshiki Watanabe, Y. Morishita, 2002, Oncogene.

Enhancement of retrovirus-mediated gene transduction efficiency by transient overexpression of the amphotropic receptor, GLVR-2.

H. Wakimoto, M. Aoyagi, H. Hamada, 1995, Nucleic acids research.

Correction of ornithine transcarbamylase deficiency in adult spf(ash) mice and in OTC-deficient human hepatocytes with recombinant adenoviruses bearing the CAG promoter.

J. Miyazaki, F. Endo, I. Matsuda, 1996, Human gene therapy.

Induction of photoreceptor-specific phenotypes in adult mammalian iris tissue

R. Kageyama, Masayo Takahashi, M. Haruta, 2001, Nature Neuroscience.

Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome.

Y. Kanegae, I. Saito, Y. Sato, 1996, Proceedings of the National Academy of Sciences of the United States of America.

The pathogenesis linked to coenzyme Q10 insufficiency in iPSC-derived neurons from patients with multiple-system atrophy

H. Okano, S. Tsuji, S. Okamoto, 2018, Scientific Reports.

Quantitative analysis of repeat adenovirus-mediated gene transfer into injured canine femoral arteries.

A. Takeshita, H. Ueno, H. Yamamoto, 1995, Arteriosclerosis, thrombosis, and vascular biology.

Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B‐positive structures

T. Mizushima, S. Kageyama, M. Komatsu, 2014, EMBO reports.

Gene therapy for hepatocellular carcinoma using two recombinant adenovirus vectors with alpha-fetoprotein promoter and Cre/lox P system.

S. Kaneko, K. Kobayashi, T. Tamaoki, 2001, Journal of virological methods.

Acetophenone 4-nitrophenylhydrazone inhibits Hepatitis B virus replication by modulating capsid assembly.

A. Nomoto, Y. Kanegae, I. Saito, 2021, Virus research.

Efficient genome replication of hepatitis B virus using adenovirus vector: a compact pregenomic RNA-expression unit

A. Nomoto, Tetsuro Suzuki, Y. Kanegae, 2017, Scientific Reports.

A New System for Stringent, High-Titer Vesicular Stomatitis Virus G Protein-Pseudotyped Retrovirus Vector Induction by Introduction of Cre Recombinase into Stable Prepackaging Cell Lines

Taiji Ito, H. Iba, F. Cosset, 1998, Journal of Virology.

Adenovirus vector expressing keratinocyte growth factor using CAG promoter impairs pulmonary function of mice with elastase‐induced emphysema

H. Oki, K. Kurahashi, T. Goto, 2017, Microbiology and immunology.

Gene therapy for α‐fetoprotein‐producing human hepatoma cells by adenovirus‐mediated transfer of the herpes simplex virus thymidine kinase gene

Keng, H. Wakimoto, Y. Shiratori, 1996, Hepatology.

Enforced dual‐specificity tyrosine‐regulated kinase 2 expression by adenovirus‐mediated gene transfer inhibits tumor growth and metastasis of colorectal cancer

Kiyotsugu Yoshida, S. Yoshida, K. Eto, 2021, Cancer science.

Direct involvement of the ubiquitin-conjugating enzyme Ubc9/Hus5 in the degradation of IκBα

S. Inoue, I. Verma, M. Pando, 1997 .

NF-κB signaling activation via increases in BRD2 and BRD4 confers resistance to the bromodomain inhibitor I-BET151 in U937 cells.

Hisashi Yamada, M. Akiyama, Y. Kanegae, 2018, Leukemia research.

Conditional gene expression in hepatitis C virus transgenic mice without induction of severe liver injury using a non-inflammatory Cre-expressing adenovirus.

M. Kohara, Y. Kanegae, I. Saito, 2011, Virus research.

Forced expression of DYRK2 exerts anti-tumor effects via apoptotic induction in liver cancer.

M. Saruta, Kiyotsugu Yoshida, S. Hirooka, 2019, Cancer letters.

CNOT3 suppression promotes necroptosis by stabilizing mRNAs for cell death-inducing proteins

Toru Suzuki, T. Natsume, Tadashi Yamamoto, 2015, Scientific Reports.

Transplantation of genetically marked cardiac muscle cells.

S. Kitamura, S. Gojo, Y. Kanegae, 1997, The Journal of thoracic and cardiovascular surgery.

Autophagy regulates lipid metabolism through selective turnover of NCoR1

Shujiro Okuda, J. Auwerx, M. Suematsu, 2019, Nature Communications.

Effect of Mitochondrial and/or Cytosolic Glycerol 3-Phosphate Dehydrogenase Overexpression on Glucose-Stimulated Insulin Secretion From MIN6 and HIT Cells

J. Miyazaki, T. Asano, H. Katagiri, 1996, Diabetes.

Percutaneous transluminal gene transfer into canine myocardium in vivo by replication-defective adenovirus.

A. Takeshita, H. Ueno, H. Yamamoto, 1995, Cardiovascular research.

Highly regulated expression of adeno-associated virus large Rep proteins in stable 293 cell lines using the Cre/loxP switching system.

H. Mizukami, K. Ozawa, M. Urabe, 1999, The Journal of general virology.

Interleukin-2 gene transduction into freshly isolated lung adenocarcinoma cells with adenoviral vectors.

N. Saijo, Y. Heike, M. Takahashi, 1997, Human gene therapy.

Long-term acceptance of allografts by in vivo gene transfer of regulatable adenovirus vector containing CTLA4IgG and loxP.

K. Tanaka, S. Todo, M. Murakami, 2001, Human gene therapy.

Origin and evolutionary characteristics of antigenic reassortant influenza A (H1N2) viruses isolated from man in China.

K. Omoe, C. Zhao, Y. Kanegae, 1992, The Journal of general virology.

Trans-complemented hepatitis C virus particles as a versatile tool for study of virus assembly and infection.

K. Ishii, Y. Matsuura, T. Wakita, 2012, Virology.

Expression of pIX gene induced by transgene promoter: possible cause of host immune response in first-generation adenoviral vectors.

M. Kanaoka, Y. Kanegae, I. Saito, 2007, Human gene therapy.

Adoptive immunotherapy with murine tumor-specific T lymphocytes engineered to secrete interleukin 2.

H. Wakimoto, M. Aoyagi, H. Hamada, 1994, Cancer research.

Evolutionary pathways of N 2 neuraminidases of swine and human influenza A viruses : origin of the neuraminidase genes of two reassortants ( H 1 N 2 ) isolated from pigs

T. Gojobori, S. Itamura, Y. Kanegae, 2007 .

Evolutionary pathways of N2 neuraminidases of swine and human influenza A viruses: origin of the neuraminidase genes of two reassortants (H1N2) isolated from pigs.

T. Gojobori, S. Itamura, Y. Kanegae, 1991, The Journal of general virology.

Activities of various FLP recombinases expressed by adenovirus vectors in mammalian cells.

Y. Kanegae, I. Saito, S. Kondo, 2009, Journal of molecular biology.

Efficient gene activation in cultured mammalian cells mediated by FLP recombinase-expressing recombinant adenovirus.

J. Chiba, Y. Kanegae, I. Saito, 2001, Nucleic acids research.

Cancer gene therapy using a pro-apoptotic gene, caspase-3

M. Narita, S. Shimizu, M. Nomura, 1999, Gene Therapy.

Highly efficient adenovirus-mediated gene transfer into renal cells in culture.

K. Kurokawa, Y. Kanegae, I. Saito, 1995, Kidney international.

Efficient production of adenovirus vector lacking genes of virus-associated RNAs that disturb cellular RNAi machinery

Y. Kanegae, I. Saito, Hiromitsu Fukuda, 2013, Scientific Reports.

Practical Range of Effective Dose for Cre Recombinase‐Expressing Recombinant Adenovirus without Cell Toxicity in Mammalian Cells

Yoshitsugu Yamada, Y. Kanegae, I. Saito, 2005, Microbiology and immunology.

Efficient Conditional Transgene Expression in Hepatitis C Virus cDNA Transgenic Mice Mediated by the Cre/loxP System*

H. Yonekawa, M. Koike, M. Kohara, 1998, The Journal of Biological Chemistry.

Influence of loxP insertion upstream of the cis‐acting packaging domain on adenovirus packaging efficiency

Y. Kanegae, I. Saito, M. Ishimura, 2012, Microbiology and immunology.

Persistent and secondary adenovirus-mediated hepatic gene expression using adenovirus vector containing CTLA4IgG.

M. Murakami, T. Yoshiki, A. Kitabatake, 1998, Human gene therapy.

Suppression of lysosomal acid alpha‐glucosidase impacts the modulation of transcription factor EB translocation in pancreatic cancer

K. Yanaga, Y. Shimada, T. Ohashi, 2021, Cancer science.

Transgenesis by adenovirus-mediated gene transfer into mouse zona-free eggs

T. Tsukui, Y. Kanegae, I. Saito, 1996, Nature Biotechnology.

Adenovirus vector technology: An efficient method for constructing recombinant adenovirus and on/off switching of gene expression

Y. Kanegae, I. Saito, Y. Sato, 1996, Acta paediatrica Japonica : Overseas edition.

[Recent progress in adenovirus vectors: focusing on VA-deleted AdV].

Y. Kanegae, I. Saito, S. Kondo, 2013, Uirusu.

Origin and evolutionary pathways of the H1 hemagglutinin gene of avian, swine and human influenza viruses: cocirculation of two distinct lineages of swine virus

K. Shortridge, K. Shortridge, Y. Kanegae, 2005, Archives of Virology.

Construction and characterization of adenoviral vector expressing biologically active brain-derived neurotrophic factor.

S. Furukawa, K. Yagi, N. Ohishi, 1995, Biochemical and biophysical research communications.

DNA Substrates Influence the Recombination Efficiency Mediated by FLP Recombinase Expressed in Mammalian Cells

J. Chiba, Y. Kanegae, I. Saito, 2001, Microbiology and immunology.

Possible Mechanism of Adenovirus Generation from a Cloned Viral Genome Tagged with Nucleotides at Its Ends

Y. Kanegae, I. Saito, Hiromitsu Fukuda, 2006, Microbiology and immunology.

Reciprocal Role of ERK and Nf-κb Pathways in Survival and Activation of Osteoclasts

Kozo Nakamura, Sakae Tanaka, I. Verma, 2000, The Journal of cell biology.

Postsynaptic expression of Ca2+-permeable AMPA-type glutamate receptor channels by viral-mediated gene transfer.

H. Okado, S. Ozawa, I. Saito, 1999, Brain research. Molecular brain research.

Evolutionary pattern of the hemagglutinin gene of influenza B viruses isolated in Japan: cocirculating lineages in the same epidemic season

Y. Kanegae, A. Oya, S. Sugita, 1990, Journal of virology.

Role of Rel/NF-κB transcription factors during the outgrowth of the vertebrate limb

I. Verma, Y. Kanegae, A. T. Tavares, 1998, Nature.

Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase.

S. Sugano, M. Tanaka, T. Sakaki, 1995, Nucleic acids research.

The pathogenesis linked to coenzyme Q10 insufficiency in iPSC-derived neurons from patients with multiple-system atrophy

H. Okano, S. Tsuji, S. Okamoto, 2018, Scientific Reports.

Critical role of CREBH‐mediated induction of transforming growth factor β2 by hepatitis C virus infection in fibrogenic responses in hepatic stellate cells

Masahiro Yamamoto, H. Shimano, T. Matsuura, 2017, Hepatology.

Induction of apoptosis after switch-on of the hepatitis B virus X gene mediated by the Cre/loxP recombination system.

K. Koike, T. Tsutsumi, H. Yotsuyanagi, 1999, The Journal of general virology.

Copy number of adenoviral vector genome transduced into target cells can be measured using quantitative PCR: application to vector titration.

Y. Kanegae, I. Saito, S. Kondo, 2012, Biochemical and biophysical research communications.

[Gene engineering of the adenovirus vector].

Yumi Kanegae, Miho Terashima, Saki Kondo, 2007, Uirusu.

Retrograde and anterograde labeling of cerebellar afferent projection by the injection of recombinant adenoviral vectors into the mouse cerebellar cortex

T. Terashima, H. Okado, Y. Kanegae, 1997, Anatomy and Embryology.

A neural cell-type-specific expression system using recombinant adenovirus vectors.

K. Mikoshiba, J. Aruga, Y. Kanegae, 1996, Human gene therapy.

Abstract of the 18th annual meeting of the Japan Neuroscience Society Tokyo, Japan, December 6–8, 1994 Communication 7. Cell biologyGene transfer into neurons by viral vectors

N. Hirokawa, T. Nakata, S. Terada, 1994 .

Short term but highly efficient Cas9 expression mediated by excisional system using adenovirus vector and Cre

K. Akimoto, Y. Kanegae, Miyuki Agawa, 2021, Scientific Reports.

α-Catenin is essential in intestinal adenoma formation

T. Noda, T. Akiyama, H. Shibata, 2007, Proceedings of the National Academy of Sciences.

A simple and efficient method for purification of infectious recombinant adenovirus.

Y. Kanegae, I. Saito, M. Makimura, 1994, Japanese journal of medical science & biology.

Comparison of efficiency between FLPe and Cre for recombinase‐mediated cassette exchange in vitro and in adenovirus vector production

Y. Kanegae, I. Saito, S. Kondo, 2011, Genes to cells : devoted to molecular & cellular mechanisms.

Complete Rescue of Lethal Albino c 14CoS Mice by Null Mutation of 4-Hydroxyphenylpyruvate Dioxygenase and Induction of Apoptosis of Hepatocytes in These Mice by in VivoRetrieval of the Tyrosine Catabolic Pathway*

J. Miyazaki, Tetsurou Yamamoto, I. Matsuda, 1997, The Journal of Biological Chemistry.

Autophagy regulates lipid metabolism through selective turnover of NCoR1

Shujiro Okuda, J. Auwerx, M. Suematsu, 2019, Nature Communications.

Efficient gene activation system on mammalian cell chromosomes using recombinant adenovirus producing Cre recombinase.

Y. Kanegae, I. Saito, Y. Sato, 1996, Gene.

Efficient Sequential Gene Regulation via FLP‐ and Cre‐Recombinase Using Adenovirus Vector in Mammalian Cells Including Mouse ES Cells

N. Yoshida, Seiji Shiozawa, Y. Kanegae, 2006, Microbiology and immunology.

Successful gene therapy via intraarticular injection of adenovirus vector containing CTLA4IgG in a murine model of type II collagen-induced arthritis.

M. Murakami, A. Kitabatake, H. Okamoto, 2001, Human gene therapy.

Recording the Fragrance of 15 Types of Medicinal Herbs and Comparing Them by Similarity Using the Electronic Nose FF-2A

Y. Kanegae, Y. Manome, N. Akiyama, 2022, Chemosensors.

Preferable sites and orientations of transgene inserted in the adenovirus vector genome: The E3 site may be unfavorable for transgene position

Y. Kanegae, I. Saito, S. Kondo, 2015, Gene Therapy.

Single-domain intrabodies against hepatitis C virus core inhibit viral propagation and core-induced NFκB activation.

Yumi Kanegae, Mitsuru Sato, Ryosuke Suzuki, 2016, The Journal of general virology.

Molecular evolution of hemagglutinin genes of H1N1 swine and human influenza A viruses

T. Gojobori, S. Itamura, Y. Kanegae, 2005, Journal of Molecular Evolution.

Gene targeting with a replication-defective adenovirus vector

I. Kobayashi, Y. Kanegae, I. Saito, 1995, Journal of virology.

High-level expression by tissue/cancer-specific promoter with strict specificity using a single-adenoviral vector

Yumi Kanegae, Miho Terashima, Saki Kondo, 2010, Nucleic Acids Res..

In vivo correction with recombinant adenovirus of 4-hydroxyphenylpyruvic acid dioxygenase deficiencies in strain III mice.

J. Miyazaki, F. Endo, I. Matsuda, 1997, Human gene therapy.

Production of viral vectors using recombinase-mediated cassette exchange

Y. Kanegae, I. Saito, M. Ishimura, 2005, Nucleic acids research.

Genetic analysis of porcine H3N2 viruses originating in southern China.

K. Shortridge, Y. Kanegae, S. Sugita, 1995, The Journal of general virology.

[Adenovirus vectors for gene therapy].

Y. Kanegae, I. Saito, S. Kondo, 2003, Uirusu.

Reversal of Hypopigmentation in Phenylketonuria Mice by Adenovirus-Mediated Gene Transfer

Kazutoshi Takahashi, Y. Matsubara, K. Narisawa, 1999, Pediatric Research.

Adenovirus vectors lacking virus-associated RNA expression enhance shRNA activity to suppress hepatitis C virus replication

Tetsuro Suzuki, G. Shi, Y. Kanegae, 2013, Scientific Reports.

Adenovirus-Encoding Virus-Associated RNAs Suppress HDGF Gene Expression to Support Efficient Viral Replication

Kenji Yoshida, Y. Kanegae, I. Saito, 2014, PloS one.

Possible role of cytotoxic T cells in acute liver injury in hepatitis C virus cDNA transgenic mice mediated by Cre/loxP system

H. Yonekawa, Y. Hiasa, M. Koike, 2000, Journal of medical virology.

Large outbreak of swine influenza in southern Japan caused by reassortant (H1N2) influenza viruses: its epizootic background and characterization of the causative viruses.

Y. Kanegae, M. Kaji, K. Nerome, 1996, The Journal of general virology.

Alpha-catenin is essential in intestinal adenoma formation.

T. Noda, T. Akiyama, H. Shibata, 2007, Proceedings of the National Academy of Sciences of the United States of America.

Adenovirus-mediated arterial gene transfer does not require prior injury for submaximal gene expression.

A. Takeshita, H. Ueno, H. Yamamoto, 1995, Gene therapy.

Specific vulnerability of iPSC-derived motor neurons with TDP-43 gene mutation to oxidative stress

H. Okano, Y. Kanegae, H. Matsuno, 2023, Molecular Brain.

Role of hepcidin upregulation and proteolytic cleavage of ferroportin 1 in hepatitis C virus-induced iron accumulation

Hirotaka Takahashi, T. Sawasaki, Satoshi Sakai, 2023, PLoS pathogens.

Keratinocyte growth factor gene transduction ameliorates pulmonary fibrosis induced by bleomycin in mice.

K. Kurahashi, T. Goto, T. Yazawa, 2011, American journal of respiratory cell and molecular biology.

Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B‐positive structures

T. Mizushima, S. Kageyama, M. Komatsu, 2014, EMBO reports.