J. Reilly

发表

Concentrations of circulating steroids in normal prepubertal and adult male and female humans, chimpanzees, rhesus monkeys, rats, mice, and hamsters: a literature survey.

J. Overpeck, S. H. Colson, J. R. Hohmann, 1978, Journal of toxicology and environmental health.

Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: A magnetic resonance microscopy and stereologic analysis

Russell E Jacobs, F. Bloom, J. Morrison, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL).

Chunlei Zhang, Madeleine Duvic, M. Duvic, 2007, Blood.

Neuroinformatics tools for visualizing gene expression in the brain

F. Bloom, J. Morrison, J. Redwine, 2004 .

Association of Fibroblast Growth Factor Receptor 1 with the Adaptor Protein Grb14

P. Maher, J. Reilly, G. Mickey, 2000, The Journal of Biological Chemistry.

Vorinostat Inhibits Brain Metastatic Colonization in a Model of Triple-Negative Breast Cancer and Induces DNA Double-Strand Breaks

P. Meltzer, S. Steinberg, K. Camphausen, 2009, Clinical Cancer Research.

Mouse models of human neurodegenerative disorders: requirements for medication development.

F. Bloom, J. Morrison, Chi-Cheng Wu, 2005, Archives of neurology.

Safety and Efficacy of GFB-887, a TRPC5 Channel Inhibitor, in Patients With Focal Segmental Glomerulosclerosis, Treatment-Resistant Minimal Change Disease, or Diabetic Nephropathy: TRACTION-2 Trial Design

Krishnan Padmanabhan, H. Heerspink, D. Gipson, 2021, Kidney international reports.

Role of Fibroblast Growth Factor-2 in Astrogliosis

J. Reilly, 2002 .

Regulation of astrocyte GFAP expression by TGF‐β1 and FGF‐2

P. Maher, J. Reilly, V. Kumari, 1998 .

Cancer Therapy : Preclinical Vorinostat Inhibits Brain Metastatic Colonization in a Model of Triple-Negative Breast Cancer and Induces DNA Double-Strand Breaks

P. Meltzer, S. Steinberg, K. Camphausen, 2009 .

Heparan sulfate modifies the effects of basic fibroblast growth factor on glial reactivity

J. Reilly, V. Kumari, Lewis Bair, 1997, Brain Research.

Importin β–Mediated Nuclear Import of Fibroblast Growth Factor Receptor

P. Maher, J. Reilly, 2001, The Journal of Cell Biology.

Importin beta-mediated nuclear import of fibroblast growth factor receptor: role in cell proliferation.

P. Maher, J. Reilly, John F. Reilly, 2001, The Journal of cell biology.

Alterations in Fibroblast Growth Factor Receptor Expression Following Brain Injury

J. Reilly, V. Kumari, 1996, Experimental Neurology.

Abstract #1751: MK-8033, a selective c-Met / Ron inhibitor, suppresses tumor cell growth in vitro and in vivo

P. Majumder, W. Lu, K. Kunii, 2009 .

Discovery of a Potent and Selective TRPC5 Inhibitor, Efficacious in a Focal Segmental Glomerulosclerosis Model.

Maolin Yu, John F. Reilly, M. Beconi, 2019, ACS medicinal chemistry letters.

Discovery of a 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) inhibitor of c-Met kinase for the treatment of cancer.

K. Kunii, M. Altman, A. Szewczak, 2011, Journal of medicinal chemistry.

Phase II trial of vorinostat in recurrent glioblastoma multiforme: a north central cancer treatment group study.

Caterina Giannini, Jan C Buckner, B. Scheithauer, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Inhibition of tumor growth progression by antiandrogens and mTOR inhibitor in a Pten-deficient mouse model of prostate cancer.

P. Majumder, S. Kasibhatla, M. Angagaw, 2009, Cancer research.

Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model.

T. Yeatman, D. Coppola, P. Majumder, 2010, Cancer research.

Ligand dependent and independent internalization and nuclear translocation of fibroblast growth factor (FGF) receptor 1.

P. Maher, J. Reilly, E. Mizukoshi, 2004, DNA and cell biology.

A novel role for farnesyl pyrophosphate synthase in fibroblast growth factor-mediated signal transduction.

P. Maher, J. Reilly, G. Mickey, 2002, The Biochemical journal.

De novo discovery of a gamma-secretase inhibitor response signature using a novel in vivo breast tumor model.

P. Majumder, J. Watters, C. Winter, 2009, Cancer research.

A quantitative volumetric micro-computed tomography method to analyze lung tumors in genetically engineered mouse models.

Raquel S. Sevilla, B. Haines, Christopher Tong, 2009, Neoplasia.

Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes.

G. Rosner, H. Kantarjian, G. Garcia-Manero, 2008, Blood.

Constitutive activation of signal transducers and activators of transcription predicts vorinostat resistance in cutaneous T-cell lymphoma.

C. Paweletz, A. Loboda, E. Harrington, 2008, Cancer research.

MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor.

C. Paweletz, K. Kunii, I. Kariv, 2010, Cancer research.

A translational kidney organoid system bolsters human relevance of clinical development candidate

M. Emani, J. Harmange, P. Mundel, 2019, bioRxiv.

Adult mouse brain gene expression patterns bear an embryologic imprint.

Matthew A. Zapala, Carrolee Barlow, F. Bloom, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Amyloid deposition in the hippocampus and entorhinal cortex: Quantitative analysis of a transgenic mouse model

F. Bloom, J. Morrison, R. Rydel, 2003, Proceedings of the National Academy of Sciences of the United States of America.

for refractory cutaneous T-cell lymphoma (CTCL) Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA)

M. Duvic, V. Richon, J. Reilly, 2013 .

Cerebral Cortex Advance Access published March 28, 2004 High-throughput Morphometric Analysis of Individual Neurons

F. Bloom, J. Morrison, J. Reilly, 2022 .

Cutaneous T-Cell Lymphoma of Transcription Predicts Vorinostat Resistance in Constitutive Activation of Signal Transducers and Activators

C. Paweletz, A. Loboda, E. Harrington, 2008 .

Transplanted organoids empower human preclinical assessment of drug candidate for the clinic

M. Emani, J. Harmange, P. Mundel, 2022, Science advances.

Discovery of 1-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide (MK-8033): A Specific c-Met/Ron dual kinase inhibitor with preferential affinity for the activated state of c-Met.

Wei Lu, Michael D Altman, Craig Rosenstein, 2013, Journal of medicinal chemistry.

Regulation of astrocyte GFAP expression by TGF-beta1 and FGF-2.

P. Maher, J. Reilly, V. Kumari, 1998, Glia.

Activity of dalotuzumab, a selective anti-IGF1R antibody, in combination with erlotinib in unselected patients with Non-small-cell lung cancer: a phase I/II randomized trial

F. Shepherd, E. Felip, T. Fitzgerald, 2014, Experimental Hematology & Oncology.

Phase Separation in Biology and Disease; Current Perspectives and Open Questions.

Diana M. Mitrea, J. Gsponer, L. Holt, 2023, Journal of molecular biology.

Experimental Therapeutics, Molecular Targets, and Chemical Biology De novo Discovery of a γ-Secretase Inhibitor Response Signature Using a Novel In vivo Breast Tumor Model

P. Majumder, J. Watters, C. Winter, 2009 .

Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes

G. Rosner, H. Kantarjian, G. Garcia-Manero, 2008 .