G. Hsieh

发表

Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI

Jill M. Wetter, G. Fox, Chih-Liang Chin, 2008, British journal of pharmacology.

Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord

Younglim Lee, Jill-Desiree Brederson, M. Jarvis, 2011, Molecular pain.

Assessing carrageenan‐induced locomotor activity impairment in rats: Comparison with evoked endpoint of acute inflammatory pain

C. Lee, A. Bannon, L. Rueter, 2012, European journal of pain.

Pharmacological modulation of movement-evoked pain in a rat model of osteoarthritis.

M. Decker, E. Blomme, P. Chandran, 2009, European journal of pharmacology.

Pharmacological characterization of A-960656, a histamine H₃ receptor antagonist with efficacy in animal models of osteoarthritis and neuropathic pain.

Jill M. Wetter, G. Diaz, J. Brioni, 2012, European journal of pharmacology.

Nephrotoxicity studies of the immunosuppressants tacrolimus (FK506) and ascomycin in rat models.

G. Hsieh, J. Andrews, K. Mollison, 1998, Toxicology.

Discovery of less nephrotoxic FK506 analogs and determining immunophilin dependence of immunosuppressant nephrotoxicity with a novel single-dose rat cisplatin potentiation assay.

G. Hsieh, J. Andrews, K. Mollison, 1997, The Journal of pharmacology and experimental therapeutics.

Structure‐activity profiles of macrolactam immunosuppressant FK‐506 analogues

G. Carter, G. Hsieh, K. Mollison, 1993, FEBS letters.

3,5-Bis(trifluoromethyl)pyrazoles: a novel class of NFAT transcription factor regulator.

Xiaoping Zhou, U. Warrior, C. Wegner, 2000, Journal of medicinal chemistry.

A-350619: a novel activator of soluble guanylyl cyclase.

M. Nakane, J. Brioni, R. Moreland, 2003, Life sciences.

A macrolactam inhibitor of T helper type 1 and T helper type 2 cytokine biosynthesis for topical treatment of inflammatory skin diseases.

J. Trevillyan, G. Carter, K. Marsh, 1999, The Journal of investigative dermatology.

A-412997 is a selective dopamine D4 receptor agonist in rats

Jill M. Wetter, J. Brioni, R. Moreland, 2005, Pharmacology Biochemistry and Behavior.

2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist

D. Donnelly-roberts, Jill M. Wetter, M. Nakane, 2005, Neuropharmacology.

RESEARCH PAPER Peripheral and central sites of action for the non-selective cannabinoid agonist WIN 55,212-2 in a rat model of post-operative pain

M. Decker, P. Chandran, P. Honore, 2009 .

Central and peripheral sites of action for CB2 receptor mediated analgesic activity in chronic inflammatory and neuropathic pain models in rats

P. Chandran, P. Honore, M. Dart, 2011, British journal of pharmacology.

Hypothalamic-pituitary-adrenocortical axis activity and immune function after oral exposure to benzene and toluene.

R. Sharma, G. Hsieh, R. Parker, 1991, Immunopharmacology.

Synthesis and evaluation of 2-amido-3-carboxamide thiophene CB₂ receptor agonists for pain management.

P. Chandran, A. Florjancic, M. Dart, 2012, Bioorganic & medicinal chemistry letters.

Indol-3-ylcycloalkyl ketones: effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity.

P. Chandran, M. Dart, M. Pai, 2010, Journal of medicinal chemistry.

Characterization of a Cannabinoid CB2 Receptor-Selective Agonist, A-836339 [2,2,3,3-Tetramethyl-cyclopropanecarboxylic Acid [3-(2-Methoxy-ethyl)-4,5-dimethyl-3H-thiazol-(2Z)-ylidene]-amide], Using in Vitro Pharmacological Assays, in Vivo Pain Models, and Pharmacological Magnetic Resonance Imaging

G. Fox, Chih-Liang Chin, P. Chandran, 2009, Journal of Pharmacology and Experimental Therapeutics.

The Immunological and Neurochemical Toxicity of Benzene and its Interaction with Toluene in Mice

G. Hsieh, 1988 .

Cytotoxicity induced by papaverine hydrochloride in fungal cell systems.

D. Acosta, J. Davila, G. Hsieh, 1990, Toxicology letters.

Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction.

D. Donnelly-roberts, Jill M. Wetter, G. Gintant, 2006, Journal of medicinal chemistry.

Toxicity assessment of toxins T-514 and T-544 of buckthorn (Karwinskia humboldtiana) in primary skin and liver cell cultures.

D. Acosta, G. Hsieh, L. Garza-Ocañas, 1992, Toxicology.

Rotationally constrained 2,4-diamino-5,6-disubstituted pyrimidines: a new class of histamine H4 receptor antagonists with improved druglikeness and in vivo efficacy in pain and inflammation models.

Jill M. Wetter, M. McPherson, J. Sullivan, 2008, Journal of medicinal chemistry.

Structure-activity studies on a series of a 2-aminopyrimidine-containing histamine H4 receptor ligands.

Jill M. Wetter, U. Warrior, M. McPherson, 2008, Journal of medicinal chemistry.

A-740003 [N-(1-{[(Cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a Novel and Selective P2X7 Receptor Antagonist, Dose-Dependently Reduces Neuropathic Pain in the Rat

D. Donnelly-roberts, J. Sullivan, P. Chandran, 2006, Journal of Pharmacology and Experimental Therapeutics.

Antidepressant-Like Effect of D2/3 Receptor-, but not D4 Receptor-Activation in the Rat Forced Swim Test

J. Brioni, M. Decker, G. Fox, 2005, Neuropsychopharmacology.

H4 receptor antagonism exhibits anti-nociceptive effects in inflammatory and neuropathic pain models in rats

Jill M. Wetter, J. Brioni, S. Baker, 2010, Pharmacology Biochemistry and Behavior.

Localization of histamine H4 receptors in the central nervous system of human and rat

J. Brioni, R. Bitner, G. Hsieh, 2009, Brain Research.

Role of central and peripheral mGluR5 receptors in post-operative pain in rats

J. Brioni, M. Decker, R. Moreland, 2005, Pain.

Antinociceptive effects of histamine H3 receptor antagonist in the preclinical models of pain in rats and the involvement of central noradrenergic systems

Jill M. Wetter, J. Brioni, M. Decker, 2010, Brain Research.

Dithranol-induced cytotoxicity in primary cultures of rat epidermal keratinocytes. I. The role of reactive oxygen species.

D. Acosta, G. Hsieh, D Acosta, 1991, Toxicology and applied pharmacology.

Subclinical effects of groundwater contaminants

Raghubir P. Sharma, G. Hsieh, R. Parker, 1990, Archives of Toxicology.

Subclinical effects of groundwater contaminants I: Alteration of and cellular immunity by benzene in CD-1 mice

Raghubir P. Sharma, G. Hsieh, R. Parker, 1988 .

Subclinical effects of groundwater contaminants. IV. Effects of repeated oral exposure to combinations of benzene and toluene on regional brain monoamine metabolism in mice

Raghubir P. Sharma, G. Hsieh, R. Parker, 2005, Archives of Toxicology.

Improved methods for transplanting split-heart neonatal cardiac grafts into the ear pinna of mice and rats.

G. Hsieh, J. Andrews, K. Mollison, 1998, Journal of pharmacological and toxicological methods.

Diaryldiamines with dual inhibition of the histamine H(3) receptor and the norepinephrine transporter and the efficacy of 4-(3-(methylamino)-1-phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol in pain.

Jill M. Wetter, J. Brioni, P. Honore, 2010, Journal of medicinal chemistry.

Subclinical effects of groundwater contaminants. II. Alteration of regional brain monoamine neurotransmitters by benzene in CD-1 mice

Raghubir P. Sharma, G. Hsieh, R. Parker, 1988, Archives of environmental contamination and toxicology.

In vitro and in vivo characterization of A‐796260: a selective cannabinoid CB2 receptor agonist exhibiting analgesic activity in rodent pain models

P. Chandran, P. Honore, C. Zhu, 2008, British journal of pharmacology.

Activation of dopamine D4 receptors by ABT-724 induces penile erection in rats.

D. Donnelly-roberts, J. Sullivan, M. Nakane, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Immunotoxicological evaluation of toluene exposure via drinking water in mice.

G. Hsieh, R. Parker, R. Sharma, 1989, Environmental research.

Subclinical effects of groundwater contaminants. I: Alteration of humoral and cellular immunity by benzene in CD-1 mice.

G. Hsieh, R. Parker, R. Sharma, 1988, Archives of environmental contamination and toxicology.

Central oxytocinergic and dopaminergic mechanisms regulating penile erection in conscious rats

R. Moreland, R. Bitner, J. Mikusa, 2005, Pharmacology Biochemistry and Behavior.

Central Mechanisms Regulating Penile Erection in Conscious Rats: The Dopaminergic Systems Related to the Proerectile Effect of Apomorphine

D. Donnelly-roberts, J. Sullivan, J. Brioni, 2004, Journal of Pharmacology and Experimental Therapeutics.

Zotarolimus, a Novel Sirolimus Analogue With Potent Anti-proliferative Activity on Coronary Smooth Muscle Cells and Reduced Potential for Systemic Immunosuppression

Yung-wu Chen, J. Trevillyan, G. Carter, 2007, Journal of cardiovascular pharmacology.

Effects of selective dopamine receptor subtype agonists on cardiac contractility and regional haemodynamics in rats

J. Segreti, J. Brioni, R. Moreland, 2004, Clinical and experimental pharmacology & physiology.

YC-1 potentiates the nitric oxide/cyclic GMP pathway in corpus cavernosum and facilitates penile erection in rats.

J. Sullivan, J. Brioni, R. Moreland, 2003, European journal of pharmacology.

Toxicity and Environmental Health Hazards of Petroleum Products in Wells Used for Drinking Water in the Intermountain West

Raghubir P. Sharma, R. Dupont, G. Hsieh, 1989 .

cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.

Jill M. Wetter, J. Brioni, P. Chandran, 2008, Journal of medicinal chemistry.

Neointimal formation after balloon-induced vascular injury in Yucatan minipigs is reduced by oral rapamycin.

C. Wegner, G. Hsieh, S. Burke, 1999, Journal of cardiovascular pharmacology.

Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction.

D. Donnelly-roberts, J. Sullivan, M. Nakane, 2004, Journal of medicinal chemistry.

Evaluation of toluene exposure via drinking water on levels of regional brain biogenic monoamines and their metabolites in CD-1 mice.

R. Coulombe, G. Hsieh, R. Parker, 1990, Ecotoxicology and environmental safety.

Discovery and biological evaluation of novel cyanoguanidine P2X(7) antagonists with analgesic activity in a rat model of neuropathic pain.

Ying Wang, Prisca Honore, Qi Shuai, 2009, Journal of medicinal chemistry.

Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test.

J. Brioni, M. Decker, G. Fox, 2005, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

Rapamycin analogs with reduced systemic exposure.

P. Wiedeman, J. Trevillyan, G. Carter, 2005, Bioorganic & medicinal chemistry letters.

Effects of macrocyclic trichothecene mycotoxins on the murine immune system

G. Hsieh, B. Jarvis, B. Hughes, 1989, Archives of environmental contamination and toxicology.

Substituted Indazoles as Nav1.7 Blockers for the Treatment of Pain.

R. Gum, T. Neelands, M. Kort, 2016, Journal of medicinal chemistry.

Indol-3-ylcycloalkyl ketones: effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity.

P. Chandran, M. Dart, M. Pai, 2010, Journal of medicinal chemistry.

The biochemical and neurologic basis for the treatment of male erectile dysfunction.

M. Nakane, J. Brioni, R. Moreland, 2001, The Journal of pharmacology and experimental therapeutics.

Antinociceptive effects of histamine H3 receptor antagonist in the preclinical models of pain in rats and the involvement of central noradrenergic systems

Jill M. Wetter, J. Brioni, M. Decker, 2010, Brain Research.

Pharmacological characterization of A-960656, a histamine H₃ receptor antagonist with efficacy in animal models of osteoarthritis and neuropathic pain.

Jill M. Wetter, G. Diaz, J. Brioni, 2012, European journal of pharmacology.

Studies on an immunosuppressive macrolactam, ascomycin: synthesis of a C-33 hydroxyl derivative.

G. Hsieh, K. Mollison, J. Luly, 1998, Bioorganic & medicinal chemistry letters.