Jon L Collins

发表

Therapeutic opportunities for liver X receptor modulators.

J. Collins, Jon L Collins, 2004, Current opinion in drug discovery & development.

Structural disorder in the complex of human pregnane X receptor and the macrolide antibiotic rifampicin.

L. Moore, S. Kliewer, M. Lambert, 2005, Molecular endocrinology.

Crystal structure of the PXR-T1317 complex provides a scaffold to examine the potential for receptor antagonism.

Timothy M Willson, William J Zuercher, T. Willson, 2007, Bioorganic & medicinal chemistry.

Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity.

Angela Smallwood, Ping Wang, Timothy M Willson, 2008, Journal of medicinal chemistry.

Direct and Indirect Mechanisms for Regulation of Fatty Acid Synthase Gene Expression by Liver X Receptors*

Peter Tontonoz, T. Osborne, R. Walczak, 2002, The Journal of Biological Chemistry.

X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by a histidine-tryptophan switch.

Derek Parks, Shawn Williams, Timothy M Willson, 2003, The Journal of biological chemistry.

Recent advances in liver X receptor biology and chemistry.

William J Zuercher, W. Zuercher, J. Collins, 2008, Current topics in medicinal chemistry.

Discovery of tertiary sulfonamides as potent liver X receptor antagonists.

Paul R Reid, Timothy M Willson, William J Zuercher, 2010, Journal of medicinal chemistry.

Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structure.

Angela Smallwood, Ping Wang, David Haigh, 2005, Journal of medicinal chemistry.

Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines.

Timothy M Willson, L. Moore, T. Willson, 2002, Journal of medicinal chemistry.

Regulation of cholesterol homeostasis by the liver X receptors in the central nervous system.

S. Kliewer, J. Collins, M. Watson, 2002, Molecular endocrinology.