Brian A McKittrick

Discovery of melanin-concentrating hormone receptor R1 antagonists using high-throughput synthesis.

Michael Czarniecki, William J Greenlee, W. Greenlee, 2005, Bioorganic & medicinal chemistry.

Design and validation of bicyclic iminopyrimidinones as beta amyloid cleaving enzyme-1 (BACE1) inhibitors: conformational constraint to favor a bioactive conformation.

William Greenlee, Lynn Hyde, Xia Chen, 2012, Journal of medicinal chemistry.

Discovery of cyclic acylguanidines as highly potent and selective beta-site amyloid cleaving enzyme (BACE) inhibitors: Part I--inhibitor design and validation.

Lingyan Wang, Andrew Stamford, Michael Czarniecki, 2010, Journal of medicinal chemistry.

Application of fragment-based NMR screening, X-ray crystallography, structure-based design, and focused chemical library design to identify novel microM leads for the development of nM BACE-1 (beta-site APP cleaving enzyme 1) inhibitors.

Michael Czarniecki, John C Hunter, William J Greenlee, 2010, Journal of medicinal chemistry.

Discovery of an Orally Available, Brain Penetrant BACE1 Inhibitor that Affords Robust CNS Aβ Reduction.

Suresh Babu, William J Greenlee, Xia Chen, 2012, ACS medicinal chemistry letters.