V. Núñez

发表

An acidic phospholipase A₂ with antibacterial activity from Porthidium nasutum snake venom.

B. Lomonte, J. Quintana, L. Vargas, 2012, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Venoms of Micrurus coral snakes: Evolutionary trends in compositional patterns emerging from proteomic analyses.

J. Calvete, L. Sanz, J. Gutiérrez, 2016, Toxicon : official journal of the International Society on Toxinology.

A randomized, blinded, comparative trial of one pepsin-digested and two whole IgG antivenoms for Bothrops snake bites in Uraba, Colombia. The Regional Group on Antivenom Therapy Research (REGATHER).

W. Dias da Silva, V. Núñez, H. G. Higashi, 1998, The American journal of tropical medicine and hygiene.

A randomized blinded clinical trial of two antivenoms, prepared by caprylic acid or ammonium sulphate fractionation of IgG, in Bothrops and Porthidium snake bites in Colombia: correlation between safety and biochemical characteristics of antivenoms.

J. Gutiérrez, V. Núñez, L. Arenas, 1999, Toxicon : official journal of the International Society on Toxinology.

Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without beta-propiolactone, in the treatment of Bothrops asper bites in Colombia.

Juan F. Silva, J. Gutiérrez, D. Warrell, 2006, Transactions of the Royal Society of Tropical Medicine and Hygiene.

MipLAAO, a new L-amino acid oxidase from the redtail coral snake Micrurus mipartitus

B. Lomonte, V. Núñez, P. Rey-Súarez, 2018, PeerJ.

Inhibitory effects of Piper umbellatum and Piper peltatum extracts towards myotoxic phospholipases A2 from Bothrops snake venoms: isolation of 4-nerolidylcatechol as active principle.

I. Merfort, R. Murillo, B. Lomonte, 2005, Phytochemistry.

Purification of nasulysin-1: A new toxin from Porthidium nasutum snake venom that specifically induces apoptosis in leukemia cell model through caspase-3 and apoptosis-inducing factor activation.

A. Bonilla-Porras, M. Jimenez-Del-Rio, C. Velez-Pardo, 2016, Toxicon : official journal of the International Society on Toxinology.

L-amino acid oxidase isolated from Micrurus mipartitus snake venom (MipLAAO) specifically induces apoptosis in acute lymphoblastic leukemia cells mostly via oxidative stress-dependent signaling mechanism.

M. Jimenez-Del-Rio, C. Velez-Pardo, V. Núñez, 2019, International journal of biological macromolecules.

Isolation and biological characterization of Batx-I, a weak hemorrhagic and fibrinogenolytic PI metalloproteinase from Colombian Bothrops atrox venom.

J. Calvete, L. Sanz, A. Rucavado, 2010, Toxicon : official journal of the International Society on Toxinology.

Integrative characterization of the venom of the coral snake Micrurus dumerilii (Elapidae) from Colombia: Proteome, toxicity, and cross-neutralization by antivenom.

B. Lomonte, Julián Fernández, V. Núñez, 2016, Journal of proteomics.

Characterization of a Lab-Scale Process to Produce Whole IgG Antivenom Covering Scorpion Stings by Genus Tityus and Centruroides of Colombia

V. Núñez, L. Preciado, S. Estrada-Gómez, 2022, Pharmaceuticals.

Scorpion envenoming in two regions of Colombia: clinical, epidemiological and therapeutic aspects.

J. Quintana, V. Núñez, J. Barona, 2004, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Proteomic and biological characterization of the venom of the redtail coral snake, Micrurus mipartitus (Elapidae), from Colombia and Costa Rica.

J. Gutiérrez, B. Lomonte, V. Núñez, 2011, Journal of proteomics.

Neutralization of the edema-forming, defibrinating and coagulant effects of Bothrops asper venom by extracts of plants used by healers in Colombia.

J. Quintana, V. Núñez, J. Barona, 2004, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Characterization and cDNA sequence of Bothriechis schlegeliil-amino acid oxidase with antibacterial activity.

J. Calvete, L. Sanz, V. Núñez, 2014, International journal of biological macromolecules.

Neutralization of Bothrops asper venom by antibodies, natural products and synthetic drugs: contributions to understanding snakebite envenomings and their treatment.

B. Lomonte, A. Rucavado, Y. Angulo, 2009, Toxicon : official journal of the International Society on Toxinology.

Inhibition of a Snake Venom Metalloproteinase by the Flavonoid Myricetin

J. Comer, V. Núñez, P. Rey-Súarez, 2018, Molecules.

Snakebites and ethnobotany in the northwest region of Colombia. Part III: neutralization of the haemorrhagic effect of Bothrops atrox venom.

V. Núñez, J. Barona, R. Otero, 2000, Journal of ethnopharmacology.

CHARACTERIZATION OF THE MOST PROMISING FRACTION OF Swietenia macrophylla ACTIVE AGAINST MYOTOXIC PHOSPHOLIPASES A2: IDENTIFICATION OF CATECHIN AS ONE OF THE ACTIVE COMPOUNDS

V. Núñez, L. Preciado, T. Lobo-Echeverri, 2016 .

Isolation and functional characterization of a basic phospholipase A2 from Colombian Bothrops asper venom

J. C. Alarcón, J. Quintana, V. Núñez, 2014 .

Correlation of the inhibitory activity of phospholipase A2 snake venom and the antioxidant activity of Colombian plant extracts

L. Vargas, V. Núñez, T. Lobo-Echeverri, 2010 .

Biochemical and biological characterization of a PLA2 from crotoxin complex of Crotalus durissus cumanensis.

S. Huancahuire-Vega, S. Marangoni, L. Ponce-Soto, 2009, Toxicon : official journal of the International Society on Toxinology.

Heterologous Expression and Immunogenic Potential of the Most Abundant Phospholipase A2 from Coral Snake Micrurus dumerilii to Develop Antivenoms

V. Núñez, J. A. Pereañez, Sergio Pulido, 2022, Toxins.

Ontogenetic variability of Bothrops atrox and Bothrops asper snake venoms from Colombia.

J. Gutiérrez, V. Núñez, R. Otero, 2003, Toxicon : official journal of the International Society on Toxinology.

Complications of Bothrops, Porthidium, and Bothriechis snakebites in Colombia. A clinical and epidemiological study of 39 cases attended in a university hospital.

W. Cornejo, V. Núñez, R. Otero, 2002, Toxicon : official journal of the International Society on Toxinology.

INHIBITORY EFFECTS OF PLANT PHENOLIC COMPOUNDS ON ENZYMATIC AND CYTOTOXIC ACTIVITIES INDUCED BY A SNAKE VENOM PHOSPHOLIPASE A2

J. Quintana, M. Londoño, V. Núñez, 2011 .

Snakebites and ethnobotany in the northwest region of Colombia: Part II: neutralization of lethal and enzymatic effects of Bothrops atrox venom.

V. Núñez, R. Otero, A. Díaz, 2000, Journal of ethnopharmacology.

Inhibition of the Toxic Effects of Lachesis muta, Crotalus durissus cumanensis and Micrurus mipartitus Snake Venoms by Plant Extracts

J. Quintana, V. Núñez, J. Barona, 2004 .

Snakebites and ethnobotany in the northwest region of Colombia: Part I: traditional use of plants.

V. Núñez, R. Otero, A. Díaz, 2000, Journal of ethnopharmacology.

The biflavonoid morelloflavone inhibits the enzymatic and biological activities of a snake venom phospholipase A2.

E. Osorio, V. Núñez, J. A. Pereañez, 2014, Chemico-biological interactions.

Preclinical assessment of the neutralizing capacity of antivenoms produced in six Latin American countries against medically-relevant Bothrops snake venoms.

J. Gutiérrez, A. Yarlequé, I. S. Sano-Martins, 2010, Toxicon : official journal of the International Society on Toxinology.

Immunorecognition and Neutralization of Crotalus durissus cumanensis Venom by a Commercial Antivenom Produced in Colombia

V. Núñez, J. A. Pereañez, P. Rey-Suárez, 2022, Toxins.

Anti-Neurotoxins from Micrurus mipartitus in the Development of Coral Snake Antivenoms

V. Núñez, P. Rey-Suárez, Ana Cardona-Ruda, 2022, Toxins.

A randomized double-blind clinical trial of two antivenoms in patients bitten by Bothrops atrox in Colombia. The Regional Group on Antivenom Therapy Research (REGATHER).

J. Gutiérrez, V. Núñez, R. Otero, 1996, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Ability of six Latin American antivenoms to neutralize the venom of mapaná equis (Bothrops atrox) from Antioquia and Chocó (Colombia).

J. Gutiérrez, V. Núñez, R. Otero, 1995, Toxicon : official journal of the International Society on Toxinology.

Neutralizing capacity of a new monovalent anti-Bothrops atrox antivenom: comparison with two commercial antivenoms.

J. Gutiérrez, V. Núñez, R. Otero, 1997, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Snake venomics and antivenomics of Bothrops atrox venoms from Colombia and the Amazon regions of Brazil, Perú and Ecuador suggest the occurrence of geographic variation of venom phenotype by a trend towards paedomorphism.

J. Calvete, L. Sanz, J. Gutiérrez, 2009, Journal of proteomics.

Snake venomics of Lachesis muta rhombeata and genus-wide antivenomics assessment of the paraspecific immunoreactivity of two antivenoms evidence the high compositional and immunological conservation across Lachesis.

J. Calvete, L. Sanz, J. Gutiérrez, 2013, Journal of proteomics.

Snake venomics across genus Lachesis. Ontogenetic changes in the venom composition of Lachesis stenophrys and comparative proteomics of the venoms of adult Lachesis melanocephala and Lachesis acrochorda.

J. Calvete, L. Sanz, M. Flores-Díaz, 2012, Journal of proteomics.

Comparative study of the venoms of three subspecies of Lachesis muta (bushmaster) from Brazil, Colombia and Costa Rica.

J. Gutiérrez, V. Núñez, R. Otero, 1998, Toxicon : official journal of the International Society on Toxinology.

Novel three-finger toxins from Micrurus dumerilii and Micrurus mipartitus coral snake venoms: Phylogenetic relationships and characterization of Clarkitoxin-I-Mdum.

B. Lomonte, V. Núñez, M. Saldarriaga-Cordoba, 2019, Toxicon : official journal of the International Society on Toxinology.

Mipartoxin-I, a novel three-finger toxin, is the major neurotoxic component in the venom of the redtail coral snake Micrurus mipartitus (Elapidae).

B. Lomonte, R. S. Floriano, L. Rodrigues-Simioni, 2012, Toxicon.

A randomized double-blind clinical trial of two antivenoms in patients bitten by Bothrops atrox in Colombia. The Regional Group on Antivenom Therapy Research (REGATHER).

J. Gutiérrez, V. Núñez, R. Otero, 1996, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Cloning and characterization of an antibacterial L-amino acid oxidase from Crotalus durissus cumanensis venom.

J. Calvete, L. Sanz, J. Quintana, 2013, Toxicon : official journal of the International Society on Toxinology.

Inhibitory effects of Swietenia macrophylla on myotoxic phospholipases A2

V. Núñez, T. Lobo-Echeverri, J. A. Pereañez, 2013 .

Structural and functional characterization of myotoxin I, a Lys49 phospholipase A2 homologue from the venom of the snake Bothrops atrox.

J. Gutiérrez, B. Lomonte, V. Núñez, 2004, Toxicon : official journal of the International Society on Toxinology.

Glycolic acid inhibits enzymatic, hemorrhagic and edema-inducing activities of BaP1, a P-I metalloproteinase from Bothrops asper snake venom: insights from docking and molecular modeling.

A. Rucavado, V. Núñez, J. A. Pereañez, 2013, Toxicon : official journal of the International Society on Toxinology.

Inhibitory Effects of Bile Acids on Enzymatic and Pharmacological Activities of a Snake Venom Phospholipase A2 from Group IIA

V. Núñez, J. A. Pereañez, A. Patiño, 2011, The protein journal.

Isolation and Functional Characterization of an Acidic Myotoxic Phospholipase A2 from Colombian Bothrops asper Venom

M. Rojas, V. Núñez, Lucilene Delazari dos Santos, 2017, Toxins.

Antibodies against a single fraction of Micrurus dumerilii venom neutralize the lethal effect of whole venom.

B. Lomonte, V. Núñez, J. A. Pereañez, 2022, Toxicology letters.

Primary structures and partial toxicological characterization of two phospholipases A2 from Micrurus mipartitus and Micrurus dumerilii coral snake venoms.

B. Lomonte, V. Núñez, M. Saldarriaga-Cordoba, 2017, Biochimie.

Characterization and cDNA sequence of Bothriechis schlegeliil-amino acid oxidase with antibacterial activity.

J. Calvete, L. Sanz, V. Núñez, 2014, International journal of biological macromolecules.